CD99 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description CD99 molecule|The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2013] (NCBI Entrez Gene Database, 4267)
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Genes

327 genes differentially expressed following the CD99 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.26641
SOST sclerostin 2.26641
ZNF726 zinc finger protein 726 2.26641
SCEL sciellin 2.26641
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.26641
CD160 CD160 molecule 2.26641
TEX11 testis expressed 11 2.26641
F11 coagulation factor XI 2.26641
CFAP74 cilia and flagella associated protein 74 2.26641
SYCP3 synaptonemal complex protein 3 2.26641
DERPC DERPC proline and glycine rich nuclear protein 2.26641
FLACC1 flagellum associated containing coiled-coil domains 1 2.26641
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.26641
MFSD6L major facilitator superfamily domain containing 6-like 2.26641
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.26641
TSPAN19 tetraspanin 19 2.26641
NPIPA8 nuclear pore complex interacting protein family, member A8 2.26641
LDLRAD2 low density lipoprotein receptor class A domain containing 2 2.26641
TMEM273 transmembrane protein 273 2.26641
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.25459
CABLES1 Cdk5 and Abl enzyme substrate 1 2.25459
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.25459
PCDHGB3 protocadherin gamma subfamily B, 3 2.25459
VSTM2A V-set and transmembrane domain containing 2A 2.25459
MFF mitochondrial fission factor 2.25459
KRT23 keratin 23, type I 2.25459
HES3 hes family bHLH transcription factor 3 2.25459
TMEM151A transmembrane protein 151A 2.25459
PRICKLE4 prickle homolog 4 (Drosophila) 2.25459
CABP4 calcium binding protein 4 2.25459
TRIM15 tripartite motif containing 15 2.25459
FUCA2 fucosidase, alpha-L- 2, plasma 2.25459
ADRB2 adrenoceptor beta 2, surface 2.25459
RXFP1 relaxin/insulin-like family peptide receptor 1 2.25459
FOXA2 forkhead box A2 2.25459
IL22RA1 interleukin 22 receptor, alpha 1 2.25459
PERM1 PPARGC1 and ESRR induced regulator, muscle 1 2.25459
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 2.25459
DLX4 distal-less homeobox 4 2.25459
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.25459
CCDC38 coiled-coil domain containing 38 2.25459
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.25459
GMNC geminin coiled-coil domain containing 2.25459
SHE Src homology 2 domain containing E 2.25459
S100A5 S100 calcium binding protein A5 2.25459
IDUA iduronidase, alpha-L- 2.25459
ICOS inducible T-cell co-stimulator 2.25459
SPNS2 spinster homolog 2 (Drosophila) 2.25459
TMEM217 transmembrane protein 217 2.25459
C9ORF152 chromosome 9 open reading frame 152 2.25459
CCL5 chemokine (C-C motif) ligand 5 2.25459
GPR25 G protein-coupled receptor 25 2.25459
MTERF4 mitochondrial transcription termination factor 4 2.25459
SLC39A5 solute carrier family 39 (zinc transporter), member 5 2.25459
HAUS2 HAUS augmin-like complex, subunit 2 2.25459
ADGB androglobin 2.25459
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 2.25459
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.25459
RPL3L ribosomal protein L3-like 2.25459
MYO16 myosin XVI 2.25459
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.25459
LY6S lymphocyte antigen 6 family member S 2.25459
LMNTD2 lamin tail domain containing 2 2.25459
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 2.25459
WDR64 WD repeat domain 64 2.25459
ASB5 ankyrin repeat and SOCS box containing 5 2.25459
FOXC1 forkhead box C1 2.25459
GPR37L1 G protein-coupled receptor 37 like 1 2.25459
GCSAM germinal center-associated, signaling and motility 2.25459
GATA4 GATA binding protein 4 2.25459
OR7D2 olfactory receptor, family 7, subfamily D, member 2 2.25459
TBC1D3B TBC1 domain family, member 3B 2.25459
MGAT4D MGAT4 family, member D 2.25459
PCDHGA9 protocadherin gamma subfamily A, 9 2.25459
LINC02268 long intergenic non-protein coding RNA 2268 2.25459
RBM33-DT RBM33 divergent transcript 2.25459
MDFIC2 MyoD family inhibitor domain containing 2 2.25459
ARMH1 armadillo like helical domain containing 1 2.25459
ARMH2 armadillo like helical domain containing 2 2.25459
MINAR2 membrane integral NOTCH2 associated receptor 2 2.25459
SMIM38 small integral membrane protein 38 2.25459
MYOCOS myocilin opposite strand 2.25459
GMCL2 germ cell-less 2, spermatogenesis associated 2.25459
LEKR1 leucine, glutamate and lysine rich 1 2.25459
MLANA melan-A 2.25459
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.25459
TMEM229A transmembrane protein 229A 2.25459
ZNF98 zinc finger protein 98 2.25459
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.25459
HLF hepatic leukemia factor 2.25459
TLR7 toll-like receptor 7 2.25459
ZACN zinc activated ligand-gated ion channel 2.25459
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2.25459
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.25459
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.25459
PCDHA7 protocadherin alpha 7 2.25459
LTBP2 latent transforming growth factor beta binding protein 2 2.25459
EDAR ectodysplasin A receptor 2.25459
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 2.25459
ABHD15 abhydrolase domain containing 15 2.25459
PGLYRP2 peptidoglycan recognition protein 2 2.25459
TMEM179 transmembrane protein 179 2.25459
PRR4 proline rich 4 (lacrimal) 2.25459
MIP major intrinsic protein of lens fiber 2.25459
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 2.25459
MEOX2 mesenchyme homeobox 2 2.25459
OR2J1 olfactory receptor, family 2, subfamily J, member 1 (gene/pseudogene) 2.25459
JTB jumping translocation breakpoint 2.25459
LGALS2 lectin, galactoside-binding, soluble, 2 2.25459
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.25459
CLIC5 chloride intracellular channel 5 2.25459
SHOX2 short stature homeobox 2 2.25459
EDN3 endothelin 3 2.25459
EFCAB9 EF-hand calcium binding domain 9 2.25459
CXCR5 chemokine (C-X-C motif) receptor 5 2.25459
CTAGE9 CTAGE family, member 9 2.25459
KLF4 Kruppel-like factor 4 (gut) 2.25459
TLL1 tolloid-like 1 2.25459
ADAM8 ADAM metallopeptidase domain 8 2.25459
SECISBP2L SECIS binding protein 2-like 2.25459
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.25459
FNDC1 fibronectin type III domain containing 1 2.25459
CYBB cytochrome b-245, beta polypeptide 2.25459
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.25459
NBPF9 neuroblastoma breakpoint family, member 9 2.25459
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.25459
PMP2 peripheral myelin protein 2 2.25459
PRF1 perforin 1 (pore forming protein) 2.25459
GSDMA gasdermin A 2.25459
PCDHGB2 protocadherin gamma subfamily B, 2 2.25459
CCDC158 coiled-coil domain containing 158 2.25459
C11ORF16 chromosome 11 open reading frame 16 2.25459
APOC4 apolipoprotein C-IV 2.25459
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.25459
ZNF512 zinc finger protein 512 2.25459
KLC2 kinesin light chain 2 2.25459
DLX3 distal-less homeobox 3 2.25459
OTOP2 otopetrin 2 2.25459
UBXN10 UBX domain protein 10 2.25459
MYLK2 myosin light chain kinase 2 2.25459
GPC1 glypican 1 2.25459
FBXO15 F-box protein 15 2.25459
GOLGA8M golgin A8 family, member M 2.25459
NTN5 netrin 5 2.25459
GSTA1 glutathione S-transferase alpha 1 2.25459
MORN5 MORN repeat containing 5 2.25459
DRD2 dopamine receptor D2 2.25459
VWA3A von Willebrand factor A domain containing 3A 2.25459
RGCC regulator of cell cycle 2.25459
ZNF366 zinc finger protein 366 2.25459
COL6A5 collagen, type VI, alpha 5 2.25459
PCDHA13 protocadherin alpha 13 2.25459
LRRC18 leucine rich repeat containing 18 2.25459
FGR FGR proto-oncogene, Src family tyrosine kinase 2.25459
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.25459
GOLGA8R golgin A8 family, member R 2.25459
TOPAZ1 testis and ovary specific PAZ domain containing 1 2.25459
TSHZ1 teashirt zinc finger homeobox 1 2.25459
POPDC2 popeye domain containing 2 2.25459
FOXB2 forkhead box B2 2.25459
NLRP8 NLR family, pyrin domain containing 8 2.25459
TMEM215 transmembrane protein 215 2.25459
KCNK18 potassium channel, two pore domain subfamily K, member 18 2.25459
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.25459
TMPRSS13 transmembrane protease, serine 13 2.25459
MAGEA10 melanoma antigen family A10 2.25459
LRRC31 leucine rich repeat containing 31 2.25459
ASCL5 achaete-scute family bHLH transcription factor 5 2.25459
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2.25459
ETV2 ets variant 2 2.25459
CRYAA crystallin, alpha A 2.25459
OIT3 oncoprotein induced transcript 3 2.25459
HIRIP3 HIRA interacting protein 3 2.25459
KRTAP5-2 keratin associated protein 5-2 2.25459
MYL7 myosin, light chain 7, regulatory 2.25459
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.25459
ZC2HC1B zinc finger, C2HC-type containing 1B 2.25459
APOA5 apolipoprotein A-V 2.25459
RTN4RL1 reticulon 4 receptor-like 1 2.25459
AMER2 APC membrane recruitment protein 2 2.25459
PLGLB1 plasminogen-like B1 2.25459
CARD6 caspase recruitment domain family, member 6 2.25459
LPAR5 lysophosphatidic acid receptor 5 2.25459
MT1M metallothionein 1M 2.25459
NPAS4 neuronal PAS domain protein 4 2.25459
SLFN12L schlafen family member 12-like 2.25459
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.25459
TMIGD2 transmembrane and immunoglobulin domain containing 2 2.25459
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.25459
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.25459
DMAC2L distal membrane arm assembly component 2 like 2.24491
ZNF114 zinc finger protein 114 2.24392
VTI1B vesicle transport through interaction with t-SNAREs 1B 2.23645
NTNG2 netrin G2 2.23518
KLHL10 kelch-like family member 10 2.23518
SCLY selenocysteine lyase 2.21672
MCPH1 microcephalin 1 2.21121
KLHL2 kelch-like family member 2 2.2107
H1-1 H1.1 linker histone, cluster member 2.18688
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.18232
CBR1 carbonyl reductase 1 2.15109
ZBTB44 zinc finger and BTB domain containing 44 2.13598
QKI QKI, KH domain containing, RNA binding 2.12976
CDK1 cyclin-dependent kinase 1 2.12255
COL17A1 collagen, type XVII, alpha 1 2.10863
CNTD1 cyclin N-terminal domain containing 1 2.10863
HPS4 Hermansky-Pudlak syndrome 4 2.10526
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 2.10526
CDK20 cyclin-dependent kinase 20 2.10526
SPNS1 spinster homolog 1 (Drosophila) 2.10526
B9D2 B9 protein domain 2 2.10526
PAQR6 progestin and adipoQ receptor family member VI 2.10526
SARM1 sterile alpha and TIR motif containing 1 2.08865
GCLC glutamate-cysteine ligase, catalytic subunit 2.08865
FAAP100 FA core complex associated protein 100 2.07995
USP54 ubiquitin specific peptidase 54 2.07745
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 2.07715
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 2.07351
RIOX1 ribosomal oxygenase 1 2.07351
FAM110B family with sequence similarity 110, member B 2.04208
AMOT angiomotin 2.04166
LAGE3 L antigen family, member 3 2.04166
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.04166
HYAL2 hyaluronoglucosaminidase 2 2.04166
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.03293
ZDHHC1 zinc finger, DHHC-type containing 1 2.03293

decreased expression

Symbol Name Standardized Value
CD99 CD99 molecule -2.26641
VWC2 von Willebrand factor C domain containing 2 -2.26641
INHBE inhibin, beta E -2.26641
BHLHE41 basic helix-loop-helix family, member e41 -2.26641
CLEC4A C-type lectin domain family 4, member A -2.26641
NOS2 nitric oxide synthase 2, inducible -2.26641
ANAPC2 anaphase promoting complex subunit 2 -2.26641
CCDC63 coiled-coil domain containing 63 -2.26641
TUBA8 tubulin, alpha 8 -2.26641
SPATA32 spermatogenesis associated 32 -2.26641
THAP6 THAP domain containing 6 -2.25459
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -2.25459
KMT2E lysine (K)-specific methyltransferase 2E -2.25459
DTX3L deltex 3 like, E3 ubiquitin ligase -2.25459
MCM6 minichromosome maintenance complex component 6 -2.25459
FAM221B family with sequence similarity 221, member B -2.25459
ELL3 elongation factor RNA polymerase II-like 3 -2.25459
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.25459
PCDHGA12 protocadherin gamma subfamily A, 12 -2.25459
TRIB2 tribbles pseudokinase 2 -2.25459
NWD2 NACHT and WD repeat domain containing 2 -2.25459
TENM1 teneurin transmembrane protein 1 -2.25459
CA7 carbonic anhydrase VII -2.25459
UBE2F ubiquitin-conjugating enzyme E2F (putative) -2.25459
SGK2 serum/glucocorticoid regulated kinase 2 -2.25459
LURAP1L leucine rich adaptor protein 1-like -2.25459
NOPCHAP1 NOP protein chaperone 1 -2.25459
H2AJ H2A.J histone -2.25459
NRDC nardilysin convertase -2.25459
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -2.25459
BST1 bone marrow stromal cell antigen 1 -2.25459
NGEF neuronal guanine nucleotide exchange factor -2.25459
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -2.25459
CLDN23 claudin 23 -2.25459
MTSS1 metastasis suppressor 1 -2.25459
CREBZF CREB/ATF bZIP transcription factor -2.25459
LEF1 lymphoid enhancer-binding factor 1 -2.25459
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.25459
LDHAL6A lactate dehydrogenase A-like 6A -2.25459
SNRPG small nuclear ribonucleoprotein polypeptide G -2.25459
KLHL32 kelch-like family member 32 -2.25459
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -2.25459
POFUT3 protein O-fucosyltransferase 3 -2.25459
NPIPB12 nuclear pore complex interacting protein family member B12 -2.25459
NLRP12 NLR family, pyrin domain containing 12 -2.25459
EBP emopamil binding protein (sterol isomerase) -2.25459
CD177 CD177 molecule -2.25459
ACADVL acyl-CoA dehydrogenase, very long chain -2.25459
COL28A1 collagen, type XXVIII, alpha 1 -2.25459
EBF4 early B-cell factor 4 -2.25459
STON2 stonin 2 -2.25459
GRK7 G protein-coupled receptor kinase 7 -2.25459
PIH1D2 PIH1 domain containing 2 -2.25459
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -2.25459
ERICH6B glutamate-rich 6B -2.25459
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -2.25459
PTDSS2 phosphatidylserine synthase 2 -2.25459
SVOP SV2 related protein homolog (rat) -2.25459
PXYLP1 2-phosphoxylose phosphatase 1 -2.25459
IGSF10 immunoglobulin superfamily, member 10 -2.25459
EFCAB12 EF-hand calcium binding domain 12 -2.25459
HLA-G major histocompatibility complex, class I, G -2.25459
LIME1 Lck interacting transmembrane adaptor 1 -2.25459
PIAS2 protein inhibitor of activated STAT, 2 -2.25459
TGM2 transglutaminase 2 -2.25459
POU5F2 POU domain class 5, transcription factor 2 -2.25459
AGBL2 ATP/GTP binding protein-like 2 -2.25459
SHISA3 shisa family member 3 -2.25459
TNMD tenomodulin -2.25459
GABPB1 GA binding protein transcription factor, beta subunit 1 -2.25459
GPR179 G protein-coupled receptor 179 -2.25459
PSORS1C2 psoriasis susceptibility 1 candidate 2 -2.25459
CFAP221 cilia and flagella associated protein 221 -2.25459
ADCY4 adenylate cyclase 4 -2.25459
JHY junctional cadherin complex regulator -2.23518
ARLN allregulin -2.23518
HMCN1 hemicentin 1 -2.22865
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 -2.22724
HIKESHI heat shock protein nuclear import factor hikeshi -2.21544
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) -2.21001
PRXL2A peroxiredoxin like 2A -2.19515
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.16447
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.13302
APLP1 amyloid beta (A4) precursor-like protein 1 -2.12823
EPC1 enhancer of polycomb homolog 1 (Drosophila) -2.11993
WDR33 WD repeat domain 33 -2.10526
TENT5B terminal nucleotidyltransferase 5B -2.07745
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -2.07351
CCK cholecystokinin -2.07265
CFAP53 cilia and flagella associated protein 53 -2.07265
C10ORF95 chromosome 10 open reading frame 95 -2.07046
HROB homologous recombination factor with OB-fold -2.06721
PDCD2 programmed cell death 2 -2.06505
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 -2.05253
GAR1 GAR1 ribonucleoprotein -2.0495
SLC25A44 solute carrier family 25, member 44 -2.04166
PGAP1 post-GPI attachment to proteins 1 -2.02716
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase -2.02637
VRTN vertebrae development associated -2.01397
GNPAT glyceronephosphate O-acyltransferase -2.01264
IQANK1 IQ motif and ankyrin repeat containing 1 -2.0021