CDC14A Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description cell division cycle 14A|The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8556)
External Link
Similar Terms
Downloads & Tools


12 substrates of the phosphatase CDC14A from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
INCENP inner centromere protein antigens 135/155kDa
IREB2 iron-responsive element binding protein 2
KIF23 kinesin family member 23
MAPK6 mitogen-activated protein kinase 6
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
TP53 tumor protein p53
USP6NL USP6 N-terminal like