CDC14B Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description cell division cycle 14B|The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8555)
External Link http://www.koehn.embl.de/depod/showp.php?gene=CDC14B
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Genes

9 substrates of the phosphatase CDC14B from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
MAPK6 mitogen-activated protein kinase 6
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TP53 tumor protein p53