CDC14B Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cell division cycle 14B|The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8555)
External Link http://www.ncbi.nlm.nih.gov/gene/8555
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13 interacting proteins for CDC14B from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CASKIN1 CASK interacting protein 1
CENPF centromere protein F, 350/400kDa
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GRB7 growth factor receptor-bound protein 7
NCAPG non-SMC condensin I complex, subunit G
NUMA1 nuclear mitotic apparatus protein 1
NUP98 nucleoporin 98kDa
PPID peptidylprolyl isomerase D
SH3GL3 SH3-domain GRB2-like 3
SIRT2 sirtuin 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
TP53 tumor protein p53