CDC25A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cell division cycle 25A|CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 993)
External Link https://ncbi.nlm.nih.gov/gene/993
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Genes

499 genes differentially expressed following the CDC25A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MGP matrix Gla protein 0.0137695
LRRC17 leucine rich repeat containing 17 0.00957546
CFI complement factor I 0.00919595
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.009045
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00816776
KIF20A kinesin family member 20A 0.00798128
SPARCL1 SPARC-like 1 (hevin) 0.00775513
IGFBP5 insulin-like growth factor binding protein 5 0.00756398
ASPH aspartate beta-hydroxylase 0.00738929
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00737037
GPM6B glycoprotein M6B 0.00728429
S100B S100 calcium binding protein B 0.00717303
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00703251
FAM107A family with sequence similarity 107, member A 0.00694164
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.00686021
NEBL nebulette 0.00676436
DCXR dicarbonyl/L-xylulose reductase 0.00675541
CD93 CD93 molecule 0.00670821
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00670269
COL9A3 collagen, type IX, alpha 3 0.00665879
CDC42 cell division cycle 42 0.00658645
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00649086
CADM1 cell adhesion molecule 1 0.00648434
AK4 adenylate kinase 4 0.00643995
SRPX2 sushi-repeat containing protein, X-linked 2 0.00642381
MT1X metallothionein 1X 0.00641662
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0063441
MSX1 msh homeobox 1 0.00633417
ADD3 adducin 3 (gamma) 0.00621599
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00619901
GOLT1B golgi transport 1B 0.00607409
FXYD6 FXYD domain containing ion transport regulator 6 0.00607291
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00602942
ACP6 acid phosphatase 6, lysophosphatidic 0.00601751
ZIC1 Zic family member 1 0.00601706
TUBB2B tubulin, beta 2B class IIb 0.00597937
MMD monocyte to macrophage differentiation-associated 0.00596581
NPTX2 neuronal pentraxin II 0.00593595
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00590995
WWTR1 WW domain containing transcription regulator 1 0.00587076
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00586728
MAP2K6 mitogen-activated protein kinase kinase 6 0.0058658
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0058412
COQ8A coenzyme Q8A 0.00583449
METTL7A methyltransferase like 7A 0.00579992
TYRP1 tyrosinase-related protein 1 0.00575058
LGALS3 lectin, galactoside-binding, soluble, 3 0.00573686
A2M alpha-2-macroglobulin 0.00573155
PUF60 poly-U binding splicing factor 60KDa 0.00571929
CCNA2 cyclin A2 0.00571309
APOB apolipoprotein B 0.00570166
FKBP5 FK506 binding protein 5 0.00567948
PLP1 proteolipid protein 1 0.00567667
COLEC12 collectin sub-family member 12 0.0056126
MT1E metallothionein 1E 0.00561088
THBS4 thrombospondin 4 0.00558773
S100A2 S100 calcium binding protein A2 0.00556372
NRN1 neuritin 1 0.00556033
SEPP1 selenoprotein P, plasma, 1 0.00552995
FABP7 fatty acid binding protein 7, brain 0.00552632
TMEM14A transmembrane protein 14A 0.00547574
EVL Enah/Vasp-like 0.00546511
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00540036
APOLD1 apolipoprotein L domain containing 1 0.00539843
PSRC1 proline/serine-rich coiled-coil 1 0.00539438
EMP2 epithelial membrane protein 2 0.0053869
NRCAM neuronal cell adhesion molecule 0.00537425
TPX2 TPX2, microtubule-associated 0.00536974
CNN3 calponin 3, acidic 0.00535036
GPX3 glutathione peroxidase 3 0.00533566
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00524764
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00523226
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00521252
XIC X chromosome inactivation center 0.00520594
MAGEA3 melanoma antigen family A3 0.00520035
CTSZ cathepsin Z 0.00519708
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00517159
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00514755
MT1F metallothionein 1F 0.00514375
HILPDA hypoxia inducible lipid droplet-associated 0.00512534
SORBS1 sorbin and SH3 domain containing 1 0.00510103
SSR1 signal sequence receptor, alpha 0.00509572
CRIP2 cysteine-rich protein 2 0.00508839
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00505921
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00505376
PLK1 polo-like kinase 1 0.00505166
FCGBP Fc fragment of IgG binding protein 0.00504253
FOXG1 forkhead box G1 0.0050191
PCYOX1L prenylcysteine oxidase 1 like 0.00501133
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00499635
LINC00623 long intergenic non-protein coding RNA 623 0.00498162
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00493145
TMSB15A thymosin beta 15a 0.00491528
MT1H metallothionein 1H 0.00490203
EPHB2 EPH receptor B2 0.00489817
DENND2D DENN/MADD domain containing 2D 0.0048809
BIRC5 baculoviral IAP repeat containing 5 0.00487955
CAPZB capping protein (actin filament) muscle Z-line, beta 0.00486421
OSTF1 osteoclast stimulating factor 1 0.00478332
DMAC2L distal membrane arm assembly component 2 like 0.0047821
SFRP1 secreted frizzled-related protein 1 0.00476983
LRRN3 leucine rich repeat neuronal 3 0.00476123
PPT1 palmitoyl-protein thioesterase 1 0.00474981
SRPX sushi-repeat containing protein, X-linked 0.00471468
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00470459
CFH complement factor H 0.00468199
GGPS1 geranylgeranyl diphosphate synthase 1 0.00468064
CRELD2 cysteine-rich with EGF-like domains 2 0.00465737
LTBP2 latent transforming growth factor beta binding protein 2 0.00463129
RBM34 RNA binding motif protein 34 0.00460067
CTSK cathepsin K 0.00459629
RNASEH2A ribonuclease H2, subunit A 0.00457118
APOC2 apolipoprotein C-II 0.00456538
ATP11B ATPase, class VI, type 11B 0.0045502
CD59 CD59 molecule, complement regulatory protein 0.00454362
PRAME preferentially expressed antigen in melanoma 0.00453278
THBD thrombomodulin 0.0044892
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00447487
MPPED2 metallophosphoesterase domain containing 2 0.00446535
PIR pirin (iron-binding nuclear protein) 0.00445938
GPC3 glypican 3 0.0044576
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00445319
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.00445209
LRP4 low density lipoprotein receptor-related protein 4 0.00440955
GLUL glutamate-ammonia ligase 0.00439002
CXCL12 chemokine (C-X-C motif) ligand 12 0.00438201
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00437913
TRMT5 tRNA methyltransferase 5 0.00436896
CRIP1 cysteine-rich protein 1 (intestinal) 0.0043658
RNASE6 ribonuclease, RNase A family, k6 0.00433293
IL17RB interleukin 17 receptor B 0.00432667
GPM6A glycoprotein M6A 0.00432521
PDIA3 protein disulfide isomerase family A, member 3 0.0043188
PFKL phosphofructokinase, liver 0.00431598
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.0043133
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00430446
MT1HL1 metallothionein 1H-like 1 0.00426351
CLU clusterin 0.0042631
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00425467
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00425346
PGAM1 phosphoglycerate mutase 1 (brain) 0.00422324
NES nestin 0.00422279
MT1G metallothionein 1G 0.00422035
APOA1 apolipoprotein A-I 0.00421743
MAB21L2 mab-21-like 2 (C. elegans) 0.00421474
HOXB6 homeobox B6 0.0042069
MECOM MDS1 and EVI1 complex locus 0.00420367
CDC45 cell division cycle 45 0.00419446
CST3 cystatin C 0.00419417
PTTG1 pituitary tumor-transforming 1 0.00417717
RBBP4 retinoblastoma binding protein 4 0.00416641
COL1A2 collagen, type I, alpha 2 0.00416457
VSIG4 V-set and immunoglobulin domain containing 4 0.00416065
NREP neuronal regeneration related protein 0.0041604
BGN biglycan 0.00415856
TWIST1 twist family bHLH transcription factor 1 0.00414622
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00413499
DCHS1 dachsous cadherin-related 1 0.00412559
CPE carboxypeptidase E 0.00412203
HMGB2 high mobility group box 2 0.00409449
TCEAL2 transcription elongation factor A (SII)-like 2 0.00409126
ECI2 enoyl-CoA delta isomerase 2 0.00408871
GPSM2 G-protein signaling modulator 2 0.00408593
CLEC11A C-type lectin domain family 11, member A 0.00408299
IFI6 interferon, alpha-inducible protein 6 0.0040509
LAMP5 lysosomal-associated membrane protein family, member 5 0.00403857
CPVL carboxypeptidase, vitellogenic-like 0.00403413
IL1R1 interleukin 1 receptor, type I 0.00400518
BCHE butyrylcholinesterase 0.00400408
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0039838
H1-10 H1.10 linker histone 0.00397433
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00397186
SOX17 SRY (sex determining region Y)-box 17 0.00397174
NSG1 neuron specific gene family member 1 0.00396615
TNNC1 troponin C type 1 (slow) 0.00395766
C7 complement component 7 0.00394464
PMP2 peripheral myelin protein 2 0.0039336
PLLP plasmolipin 0.00393262
ERG28 ergosterol biosynthesis 28 homolog 0.00393048
AK2 adenylate kinase 2 0.00392837
LMNB1 lamin B1 0.0039272
FGFR3 fibroblast growth factor receptor 3 0.003914
REG3A regenerating islet-derived 3 alpha 0.00391035
HOXB7 homeobox B7 0.00390234
ALB albumin 0.00389643
DCT dopachrome tautomerase 0.00389625
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00388834
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00387104
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00386808
GNAS GNAS complex locus 0.00386214
PPAP2A phosphatidic acid phosphatase type 2A 0.00386146
RGS5 regulator of G-protein signaling 5 0.00385654
QKI QKI, KH domain containing, RNA binding 0.00385423
PBX3 pre-B-cell leukemia homeobox 3 0.00385177
ADI1 acireductone dioxygenase 1 0.00384928
HPF1 histone PARylation factor 1 0.00384317
B3GNT1 0.00384171
TMEM204 transmembrane protein 204 0.00383985
TNS3 tensin 3 0.00383173
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00382609
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00382382
SYBU syntabulin (syntaxin-interacting) 0.00382049
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00380126
NCAM1 neural cell adhesion molecule 1 0.00379356
MIA melanoma inhibitory activity 0.0037874
DAD1 defender against cell death 1 0.00378707
SYNM synemin, intermediate filament protein 0.00378357
ACSF2 acyl-CoA synthetase family member 2 0.00377933
GRB14 growth factor receptor-bound protein 14 0.00377167
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00376907
PEX2 peroxisomal biogenesis factor 2 0.00376749
AQP4 aquaporin 4 0.00376482
PLN phospholamban 0.0037604
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00376001
MATN2 matrilin 2 0.00375854
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00375782
REG1A regenerating islet-derived 1 alpha 0.00375746
SPC25 SPC25, NDC80 kinetochore complex component 0.00374191
DCPS decapping enzyme, scavenger 0.00372727
DACH1 dachshund family transcription factor 1 0.00371946
PMEL premelanosome protein 0.00371737
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.00371045
GMDS GDP-mannose 4,6-dehydratase 0.0037102
NCAPD2 non-SMC condensin I complex, subunit D2 0.00370345
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00370242
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.00369373
MAPK1 mitogen-activated protein kinase 1 0.0036857
PDZRN3 PDZ domain containing ring finger 3 0.00368207
LZTS1 leucine zipper, putative tumor suppressor 1 0.00367986
NUSAP1 nucleolar and spindle associated protein 1 0.00367907
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.00366792
SCRG1 stimulator of chondrogenesis 1 0.00366301
C21ORF33 chromosome 21 open reading frame 33 0.0036519
SORD sorbitol dehydrogenase 0.00364747
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00364372
RNASET2 ribonuclease T2 0.00364269
CHEK1 checkpoint kinase 1 0.00364175
F8 coagulation factor VIII, procoagulant component 0.00364141
ENG endoglin 0.00363739
SRP9 signal recognition particle 9kDa 0.0036363
PCOLCE procollagen C-endopeptidase enhancer 0.00363371
CYTL1 cytokine-like 1 0.00363276
CCNB1 cyclin B1 0.00362831
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00362614
FMOD fibromodulin 0.00361814
FTO fat mass and obesity associated 0.00361794
APOC3 apolipoprotein C-III 0.00361668
ADIRF adipogenesis regulatory factor 0.00361118
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 0.00360679

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0159809
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00918163
CDC25A cell division cycle 25A -0.00864226
SIK1 salt-inducible kinase 1 -0.00792913
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0079032
S100P S100 calcium binding protein P -0.00751979
DUSP5 dual specificity phosphatase 5 -0.00731666
SLC38A1 solute carrier family 38, member 1 -0.00700338
BASP1 brain abundant, membrane attached signal protein 1 -0.00699729
NRIP1 nuclear receptor interacting protein 1 -0.00694875
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00693147
KRT7 keratin 7, type II -0.00685061
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00673217
TOX3 TOX high mobility group box family member 3 -0.00668691
MSMB microseminoprotein, beta- -0.00667427
MAP7 microtubule-associated protein 7 -0.00664067
MIR22HG MIR22 host gene -0.00662309
MFAP5 microfibrillar associated protein 5 -0.00658691
RAB9A RAB9A, member RAS oncogene family -0.00656341
IRS2 insulin receptor substrate 2 -0.00649192
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00649021
HOXD1 homeobox D1 -0.00643816
GREM1 gremlin 1, DAN family BMP antagonist -0.00628624
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00619487
CA12 carbonic anhydrase XII -0.00601597
NVL nuclear VCP-like -0.00601553
MUC4 mucin 4, cell surface associated -0.00599287
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00592197
AKAP8 A kinase (PRKA) anchor protein 8 -0.00592026
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00589663
DCLK1 doublecortin-like kinase 1 -0.00588384
TFPI2 tissue factor pathway inhibitor 2 -0.00580425
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00576057
LCN2 lipocalin 2 -0.00573369
ZC3H12A zinc finger CCCH-type containing 12A -0.00565303
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00564204
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.00561864
RBPMS RNA binding protein with multiple splicing -0.00558986
OXSR1 oxidative stress responsive 1 -0.0055879
IER5 immediate early response 5 -0.0055484
BAG3 BCL2-associated athanogene 3 -0.00554304
CRISP3 cysteine-rich secretory protein 3 -0.00553316
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00551054
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00550414
DSE dermatan sulfate epimerase -0.00549548
PDZK1IP1 PDZK1 interacting protein 1 -0.00548409
FTH1 ferritin, heavy polypeptide 1 -0.00546158
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00543056
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00540977
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0053749
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00533433
PPIF peptidylprolyl isomerase F -0.00529032
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00522012
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.0052152
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00516385
S100A12 S100 calcium binding protein A12 -0.0051108
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00510877
OPTN optineurin -0.0050624
MSLN mesothelin -0.00505666
LTF lactotransferrin -0.00504035
NUP58 nucleoporin 58 -0.00503581
BMP2K BMP2 inducible kinase -0.00503007
BPIFA1 BPI fold containing family A, member 1 -0.00502708
OSBPL10 oxysterol binding protein-like 10 -0.00502535
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00499836
INAVA innate immunity activator -0.00498569
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00498341
RAB21 RAB21, member RAS oncogene family -0.00494938
PTGES prostaglandin E synthase -0.00494048
DUSP10 dual specificity phosphatase 10 -0.00493567
ZNF331 zinc finger protein 331 -0.00492826
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00490952
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00490612
SOCS1 suppressor of cytokine signaling 1 -0.00481892
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.004816
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00479693
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00479124
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00478195
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00476966
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00475704
WT1 Wilms tumor 1 -0.00473784
ARMCX3 armadillo repeat containing, X-linked 3 -0.00470883
PERP PERP, TP53 apoptosis effector -0.00470806
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00467645
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00466405
KRT14 keratin 14, type I -0.00465474
UBE3C ubiquitin protein ligase E3C -0.00464846
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00464611
HBEGF heparin-binding EGF-like growth factor -0.00463954
SFTPB surfactant protein B -0.00463444
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00463043
PROM1 prominin 1 -0.00462267
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00461944
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -0.00461474
RNF6 ring finger protein (C3H2C3 type) 6 -0.00460429
C3ORF52 chromosome 3 open reading frame 52 -0.00457766
KCTD5 potassium channel tetramerization domain containing 5 -0.00455795
PFKM phosphofructokinase, muscle -0.00453653
TUFT1 tuftelin 1 -0.00453477
NOTCH1 notch 1 -0.00452684
TSC22D2 TSC22 domain family, member 2 -0.00451848
DAPK1 death-associated protein kinase 1 -0.00451553
RUNX3 runt-related transcription factor 3 -0.00451525
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00450668
SLC44A4 solute carrier family 44, member 4 -0.00449678
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00448848
LRPPRC leucine-rich pentatricopeptide repeat containing -0.00445977
SUB1 SUB1 homolog (S. cerevisiae) -0.00445826
CCP110 centriolar coiled coil protein 110kDa -0.00444725
CLGN calmegin -0.00444212
MAPK6 mitogen-activated protein kinase 6 -0.00443407
RPS27L ribosomal protein S27-like -0.00441059
ATF3 activating transcription factor 3 -0.00437761
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.0043737
PAWR PRKC, apoptosis, WT1, regulator -0.00437115
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00435411
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.00434776
RAP2C RAP2C, member of RAS oncogene family -0.00434191
RNF19B ring finger protein 19B -0.00433547
PKP1 plakophilin 1 -0.0043339
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00432514
KRT34 keratin 34, type I -0.00430584
ODC1 ornithine decarboxylase 1 -0.00429898
SMAD7 SMAD family member 7 -0.00429442
OXTR oxytocin receptor -0.0042893
THBS1 thrombospondin 1 -0.0042868
CSTA cystatin A (stefin A) -0.00424625
KRT6A keratin 6A, type II -0.004242
BRPF1 bromodomain and PHD finger containing, 1 -0.00424065
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -0.00422188
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.0042213
XK X-linked Kx blood group -0.00420846
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -0.00418281
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00417602
IRF1 interferon regulatory factor 1 -0.00417525
SFTPA2 surfactant protein A2 -0.00417378
MICB MHC class I polypeptide-related sequence B -0.00417218
EGR2 early growth response 2 -0.00416606
ATP5MF ATP synthase membrane subunit f -0.00416314
DPYSL2 dihydropyrimidinase-like 2 -0.00416052
MED13L mediator complex subunit 13-like -0.00415429
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00415093
PLK2 polo-like kinase 2 -0.00414086
NT5E 5'-nucleotidase, ecto (CD73) -0.00413131
TSPYL5 TSPY-like 5 -0.00412809
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00412234
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -0.00411563
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -0.00410056
MCOLN1 mucolipin 1 -0.00409821
SFN stratifin -0.00409637
HSPA4L heat shock 70kDa protein 4-like -0.00409337
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00408832
STC1 stanniocalcin 1 -0.00408472
TGFA transforming growth factor, alpha -0.00408028
NCOA3 nuclear receptor coactivator 3 -0.00406819
MTCL1 microtubule crosslinking factor 1 -0.0040662
ELANE elastase, neutrophil expressed -0.00405194
NOP10 NOP10 ribonucleoprotein -0.00405016
CLDN4 claudin 4 -0.00403927
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.0040379
SIRT1 sirtuin 1 -0.00403527
PRKCI protein kinase C, iota -0.00402986
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00401273
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00400843
HBD hemoglobin, delta -0.00399607
CORO2A coronin, actin binding protein, 2A -0.0039828
JMJD6 jumonji domain containing 6 -0.00397358
CFB complement factor B -0.00396631
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00396435
CLCA2 chloride channel accessory 2 -0.00396326
HK2 hexokinase 2 -0.00396266
KLC2 kinesin light chain 2 -0.00396059
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.00395849
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -0.00395218
SIX2 SIX homeobox 2 -0.00395096
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00394634
PIGA phosphatidylinositol glycan anchor biosynthesis, class A -0.00394315
CDCP1 CUB domain containing protein 1 -0.00394307
DTX4 deltex 4, E3 ubiquitin ligase -0.00393505
TCTA T-cell leukemia translocation altered -0.00393137
SPAG1 sperm associated antigen 1 -0.0039302
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00392679
PTER phosphotriesterase related -0.00391068
EMC3 ER membrane protein complex subunit 3 -0.00390941
POU2AF1 POU class 2 associating factor 1 -0.00390932
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00390713
RBM38 RNA binding motif protein 38 -0.00388883
COL11A1 collagen, type XI, alpha 1 -0.00388784
TMPRSS2 transmembrane protease, serine 2 -0.00387568
ADCY9 adenylate cyclase 9 -0.00387322
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00387308
HSPA1A heat shock 70kDa protein 1A -0.00387164
TUBB6 tubulin, beta 6 class V -0.00386625
CYB5R2 cytochrome b5 reductase 2 -0.00386232
PFDN4 prefoldin subunit 4 -0.00384825
GRB7 growth factor receptor-bound protein 7 -0.00384264
SGK1 serum/glucocorticoid regulated kinase 1 -0.00383773
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00383571
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -0.00383439
NPAS2 neuronal PAS domain protein 2 -0.00383285
ISG20 interferon stimulated exonuclease gene 20kDa -0.00382497
ZCCHC2 zinc finger, CCHC domain containing 2 -0.0038092
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.0037976
SPAG6 sperm associated antigen 6 -0.00379107
CHD1 chromodomain helicase DNA binding protein 1 -0.00378842
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00376852
S100A8 S100 calcium binding protein A8 -0.00376766
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00376765
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00376748
COL10A1 collagen, type X, alpha 1 -0.00375226
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00374747
GSE1 Gse1 coiled-coil protein -0.00374697
ATXN7 ataxin 7 -0.00374258
CYBA cytochrome b-245, alpha polypeptide -0.00374243
FEM1B fem-1 homolog b (C. elegans) -0.00373493
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00373331
ZNF217 zinc finger protein 217 -0.00372586
ASS1 argininosuccinate synthase 1 -0.00370375
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00370319
TSC22D1 TSC22 domain family, member 1 -0.00370052
IL11 interleukin 11 -0.00368842
RRAGC Ras-related GTP binding C -0.00367988
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.00367918
CLCA4 chloride channel accessory 4 -0.00367108
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00366422
PAEP progestagen-associated endometrial protein -0.00365703
PCF11 PCF11 cleavage and polyadenylation factor subunit -0.00365316
YBX3 Y box binding protein 3 -0.00364994
PHACTR2 phosphatase and actin regulator 2 -0.00364379
ZBTB43 zinc finger and BTB domain containing 43 -0.00363827
RND3 Rho family GTPase 3 -0.00363492
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -0.00363488
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00363435
SETD5 SET domain containing 5 -0.00362194
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0036097
RREB1 ras responsive element binding protein 1 -0.00360927
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0036075
LBH limb bud and heart development -0.00359789
S100A9 S100 calcium binding protein A9 -0.00359679
EPHA2 EPH receptor A2 -0.00359261
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00359119
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00359093
SLC25A38 solute carrier family 25, member 38 -0.00358991
HAUS3 HAUS augmin-like complex, subunit 3 -0.00358748
IL32 interleukin 32 -0.00358716
SECISBP2L SECIS binding protein 2-like -0.00358432
CDC34 cell division cycle 34 -0.0035758
IL18 interleukin 18 -0.00357216
AKAP10 A kinase (PRKA) anchor protein 10 -0.00357164
OSBPL3 oxysterol binding protein-like 3 -0.00356752