CDC25C Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cell division cycle 25C|This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 995)
External Link https://ncbi.nlm.nih.gov/gene/995
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Genes

499 genes differentially expressed following the CDC25C gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT7 keratin 7, type II 0.0141178
GRB7 growth factor receptor-bound protein 7 0.0138461
EIF5A eukaryotic translation initiation factor 5A 0.0137304
AKAP12 A kinase (PRKA) anchor protein 12 0.0133234
CLU clusterin 0.0133144
CA2 carbonic anhydrase II 0.012992
IRS2 insulin receptor substrate 2 0.0114415
CHP1 calcineurin-like EF-hand protein 1 0.0112875
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0109727
CD14 CD14 molecule 0.0105497
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0104838
NRCAM neuronal cell adhesion molecule 0.0103583
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.0102814
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0100658
PCDH9 protocadherin 9 0.00983185
COG7 component of oligomeric golgi complex 7 0.0098102
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.00956498
KLF9 Kruppel-like factor 9 0.00940504
F3 coagulation factor III (thromboplastin, tissue factor) 0.0093759
CP ceruloplasmin (ferroxidase) 0.00936374
SIK1 salt-inducible kinase 1 0.00927883
CYB5R2 cytochrome b5 reductase 2 0.00915891
XIC X chromosome inactivation center 0.00912607
PLK2 polo-like kinase 2 0.00912488
MGLL monoglyceride lipase 0.00895899
TFRC transferrin receptor 0.00895706
PLXNB2 plexin B2 0.00893899
IL17RB interleukin 17 receptor B 0.00893438
RTN2 reticulon 2 0.00890488
HSPA1A heat shock 70kDa protein 1A 0.00879767
DUSP1 dual specificity phosphatase 1 0.00876737
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.0087624
CRP C-reactive protein, pentraxin-related 0.00873654
KRT23 keratin 23, type I 0.00870604
NPTX2 neuronal pentraxin II 0.00866702
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00865621
CFH complement factor H 0.00856644
FGA fibrinogen alpha chain 0.00844458
MT1X metallothionein 1X 0.00840997
GPM6B glycoprotein M6B 0.00837168
BLNK B-cell linker 0.00835152
FN1 fibronectin 1 0.00831406
RB1 retinoblastoma 1 0.00829782
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00826299
PEG3 paternally expressed 3 0.00822269
ZNF589 zinc finger protein 589 0.00818083
SMC1A structural maintenance of chromosomes 1A 0.00811008
ARHGAP29 Rho GTPase activating protein 29 0.008046
CD36 CD36 molecule (thrombospondin receptor) 0.00802334
ASPH aspartate beta-hydroxylase 0.0079903
RND3 Rho family GTPase 3 0.00795451
AGTR1 angiotensin II receptor, type 1 0.00792794
SIRPA signal-regulatory protein alpha 0.0079062
CAST calpastatin 0.0078915
VTN vitronectin 0.00788043
CAV2 caveolin 2 0.0078711
CANX calnexin 0.00784719
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00777362
CFHR2 complement factor H-related 2 0.00772671
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00759338
MT3 metallothionein 3 0.00757827
SGK1 serum/glucocorticoid regulated kinase 1 0.00754885
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00754065
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00753989
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00753862
AHNAK AHNAK nucleoprotein 0.00753746
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00749232
S100A9 S100 calcium binding protein A9 0.00746751
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0074539
NPAS2 neuronal PAS domain protein 2 0.0074527
PERP PERP, TP53 apoptosis effector 0.00744693
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00738881
CNTN1 contactin 1 0.00738648
TSPO translocator protein (18kDa) 0.00738238
AOX1 aldehyde oxidase 1 0.00737403
GBAP1 glucosidase, beta, acid pseudogene 1 0.00735964
C5AR1 complement component 5a receptor 1 0.00734845
CDO1 cysteine dioxygenase type 1 0.00730467
SYT17 synaptotagmin XVII 0.00728314
EZR ezrin 0.00724535
PON2 paraoxonase 2 0.00722016
OAT ornithine aminotransferase 0.00719554
WEE1 WEE1 G2 checkpoint kinase 0.00710335
SOX9 SRY (sex determining region Y)-box 9 0.00709335
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00708249
MNDA myeloid cell nuclear differentiation antigen 0.00704758
KIAA0100 KIAA0100 0.00703693
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.00703419
CSRP2 cysteine and glycine-rich protein 2 0.00701996
ATF3 activating transcription factor 3 0.00700742
PUF60 poly-U binding splicing factor 60KDa 0.00694171
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00693245
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00690575
IGSF3 immunoglobulin superfamily, member 3 0.00684992
LYPD3 LY6/PLAUR domain containing 3 0.0068376
NUDC nudC nuclear distribution protein 0.00682328
SGCE sarcoglycan, epsilon 0.00680191
ZIC1 Zic family member 1 0.00679362
HHEX hematopoietically expressed homeobox 0.00678478
PDZD2 PDZ domain containing 2 0.00678342
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0067762
APLP1 amyloid beta (A4) precursor-like protein 1 0.00677414
MT1G metallothionein 1G 0.00674975
ALB albumin 0.00673706
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.00673639
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00672924
GSTA1 glutathione S-transferase alpha 1 0.00672566
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.0067234
FOXC1 forkhead box C1 0.00672227
MT1H metallothionein 1H 0.00670287
DMXL2 Dmx-like 2 0.00669282
TRIM29 tripartite motif containing 29 0.00665803
MAOB monoamine oxidase B 0.00665538
EMP1 epithelial membrane protein 1 0.00664734
SCAND1 SCAN domain containing 1 0.00662747
C14ORF132 chromosome 14 open reading frame 132 0.00661295
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00660563
FXYD6 FXYD domain containing ion transport regulator 6 0.00656442
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00656015
BAALC brain and acute leukemia, cytoplasmic 0.00654882
BTG1 B-cell translocation gene 1, anti-proliferative 0.00654049
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00653172
BICC1 BicC family RNA binding protein 1 0.00649343
GLUD2 glutamate dehydrogenase 2 0.00647918
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00645078
GPX1 glutathione peroxidase 1 0.00641898
ANGPT1 angiopoietin 1 0.0064085
PLP1 proteolipid protein 1 0.00639194
FGL1 fibrinogen-like 1 0.00638161
MT2A metallothionein 2A 0.0063587
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00635069
LOX lysyl oxidase 0.00633508
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00633192
PSCA prostate stem cell antigen 0.00632613
CRIP2 cysteine-rich protein 2 0.00632109
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.00631235
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00628424
THBS1 thrombospondin 1 0.00627382
C3 complement component 3 0.00625854
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.00624966
NCALD neurocalcin delta 0.00624882
MPST mercaptopyruvate sulfurtransferase 0.00623406
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.0061918
MCM2 minichromosome maintenance complex component 2 0.00617585
KYNU kynureninase 0.00616761
PXDN peroxidasin 0.00615903
TUBB2A tubulin, beta 2A class IIa 0.0061571
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.00612748
RPL10 ribosomal protein L10 0.00612539
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.00611659
CAPRIN2 caprin family member 2 0.00611283
SCPEP1 serine carboxypeptidase 1 0.00611068
HILPDA hypoxia inducible lipid droplet-associated 0.00611008
L1CAM L1 cell adhesion molecule 0.00610346
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00609393
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00607503
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00607342
DMD dystrophin 0.006069
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.00606617
MT1HL1 metallothionein 1H-like 1 0.00603451
HOXB2 homeobox B2 0.00603402
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00602356
HOMER3 homer scaffolding protein 3 0.00600438
PRNP prion protein 0.00599597
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.00599383
SLC38A2 solute carrier family 38, member 2 0.00597927
MREG melanoregulin 0.00597768
PCNA proliferating cell nuclear antigen 0.00596993
COMT catechol-O-methyltransferase 0.00594761
TCTA T-cell leukemia translocation altered 0.00593784
MT1E metallothionein 1E 0.00593613
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00589956
EHD3 EH-domain containing 3 0.00588924
INA internexin neuronal intermediate filament protein, alpha 0.00588544
PROM1 prominin 1 0.00587592
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00587164
MVP major vault protein 0.0058522
HAL histidine ammonia-lyase 0.00584902
TM4SF4 transmembrane 4 L six family member 4 0.00584546
KLF6 Kruppel-like factor 6 0.00584163
DCN decorin 0.00583877
ITGB4 integrin, beta 4 0.00583004
MIR22HG MIR22 host gene 0.00581308
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00580551
EPHA2 EPH receptor A2 0.00579886
A2M alpha-2-macroglobulin 0.00578026
GPI glucose-6-phosphate isomerase 0.00575553
PEG10 paternally expressed 10 0.00575446
SRPX2 sushi-repeat containing protein, X-linked 2 0.00575314
FOXD1 forkhead box D1 0.00575309
APCS amyloid P component, serum 0.00574687
ASGR2 asialoglycoprotein receptor 2 0.00572938
MYO1B myosin IB 0.00571952
LRRN3 leucine rich repeat neuronal 3 0.00570982
VSIG4 V-set and immunoglobulin domain containing 4 0.00570854
RELN reelin 0.00570467
GPC1 glypican 1 0.00570106
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.00569296
ATF4 activating transcription factor 4 0.00569058
FKBP5 FK506 binding protein 5 0.0056805
SOD2 superoxide dismutase 2, mitochondrial 0.00567965
NEFH neurofilament, heavy polypeptide 0.00567128
KLK6 kallikrein-related peptidase 6 0.00566191
CD58 CD58 molecule 0.00564243
ANXA10 annexin A10 0.00563153
PLSCR4 phospholipid scramblase 4 0.00563139
IL13RA1 interleukin 13 receptor, alpha 1 0.00561952
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.00561868
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.00561527
BEX1 brain expressed, X-linked 1 0.00561411
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.00560914
ARHGAP12 Rho GTPase activating protein 12 0.00560396
PAH phenylalanine hydroxylase 0.00559593
H1-0 H1.0 linker histone 0.00557226
PDAP1 PDGFA associated protein 1 0.00557104
AKR1C2 aldo-keto reductase family 1, member C2 0.0055607
SLC43A3 solute carrier family 43, member 3 0.00555928
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00555422
BID BH3 interacting domain death agonist 0.00554222
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00553439
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00551938
IL17RA interleukin 17 receptor A 0.00549782
TLR5 toll-like receptor 5 0.00547581
GAS7 growth arrest-specific 7 0.00545711
C7 complement component 7 0.00545281
ORM1 orosomucoid 1 0.00544756
MAT1A methionine adenosyltransferase I, alpha 0.00544701
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.00544364
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00544036
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00543713
WDR13 WD repeat domain 13 0.00543028
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00542258
SIX2 SIX homeobox 2 0.00540755
NDRG2 NDRG family member 2 0.00540507
EREG epiregulin 0.00540387
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.0053949
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00538924
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00538455
TAGLN2 transgelin 2 0.00536656
GLA galactosidase, alpha 0.00536246
NRIP3 nuclear receptor interacting protein 3 0.00536159
LOXL2 lysyl oxidase-like 2 0.00533918
AKAP9 A kinase (PRKA) anchor protein 9 0.00532998
FAM107A family with sequence similarity 107, member A 0.00532816
EIF6 eukaryotic translation initiation factor 6 0.00532295
INHBB inhibin, beta B 0.00532271
ZNF331 zinc finger protein 331 0.00532222
CES1 carboxylesterase 1 0.00531745
SOX11 SRY (sex determining region Y)-box 11 0.00530827
MEOX2 mesenchyme homeobox 2 0.0053019

decreased expression

Symbol Name Standardized Value
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0203691
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0183038
OLFM4 olfactomedin 4 -0.0182918
ESR1 estrogen receptor 1 -0.0146521
NELL2 NEL-like 2 (chicken) -0.0139363
JCHAIN joining chain of multimeric IgA and IgM -0.0137589
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0135459
IFITM1 interferon induced transmembrane protein 1 -0.0125421
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.0123949
ABHD4 abhydrolase domain containing 4 -0.0117453
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0115297
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0114368
AOC1 amine oxidase, copper containing 1 -0.0112363
TFF1 trefoil factor 1 -0.0109892
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0109698
TFF3 trefoil factor 3 (intestinal) -0.0109311
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.010142
CLCA1 chloride channel accessory 1 -0.00996835
DMBT1 deleted in malignant brain tumors 1 -0.00983863
TXNDC9 thioredoxin domain containing 9 -0.00950142
TLCD3A TLC domain containing 3A -0.00916876
STC1 stanniocalcin 1 -0.00907931
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00887266
THAP12 THAP domain containing 12 -0.00884848
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00874248
CTSZ cathepsin Z -0.00873784
MATN2 matrilin 2 -0.00860821
LAPTM4B lysosomal protein transmembrane 4 beta -0.00860806
SFRP1 secreted frizzled-related protein 1 -0.00839842
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00838719
ATP10B ATPase, class V, type 10B -0.0083483
PDZK1IP1 PDZK1 interacting protein 1 -0.00834735
MMP7 matrix metallopeptidase 7 -0.00833685
CCL5 chemokine (C-C motif) ligand 5 -0.00829177
RPS5 ribosomal protein S5 -0.0082761
NDNF neuron-derived neurotrophic factor -0.00824236
KDM5D lysine (K)-specific demethylase 5D -0.00822072
LEFTY1 left-right determination factor 1 -0.00821801
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00811862
DPYSL3 dihydropyrimidinase-like 3 -0.00811358
DUOX2 dual oxidase 2 -0.00809219
KRCC1 lysine-rich coiled-coil 1 -0.00803902
MSX1 msh homeobox 1 -0.00802982
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.0080121
NDUFA4 NDUFA4, mitochondrial complex associated -0.00800437
GNAS GNAS complex locus -0.00795442
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00790591
GPA33 glycoprotein A33 (transmembrane) -0.00785485
NMU neuromedin U -0.00780163
SVIL supervillin -0.00778852
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00772384
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00772085
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.00766642
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00762662
CD48 CD48 molecule -0.00758228
GREB1 growth regulation by estrogen in breast cancer 1 -0.00757038
CD96 CD96 molecule -0.00757
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00754903
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00744733
PPA2 pyrophosphatase (inorganic) 2 -0.00741974
NKX2-1 NK2 homeobox 1 -0.00736771
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.0073656
GCH1 GTP cyclohydrolase 1 -0.00735834
ATP5F1E ATP synthase F1 subunit epsilon -0.00729132
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00728038
CCDC92 coiled-coil domain containing 92 -0.00727516
FAM46C family with sequence similarity 46, member C -0.0072722
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00719032
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00718779
LMNB1 lamin B1 -0.00717681
AKAP7 A kinase (PRKA) anchor protein 7 -0.00712908
GNLY granulysin -0.00710413
SYNJ2 synaptojanin 2 -0.00709796
CKAP2 cytoskeleton associated protein 2 -0.00704441
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00703685
PLN phospholamban -0.00699996
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00698721
DCK deoxycytidine kinase -0.00698655
S100A2 S100 calcium binding protein A2 -0.00694533
CHKB choline kinase beta -0.00692306
RETREG1 reticulophagy regulator 1 -0.00688491
CD38 CD38 molecule -0.00682935
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00682657
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.00680557
CLEC2B C-type lectin domain family 2, member B -0.00679236
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00678258
SCG5 secretogranin V -0.0067699
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00669204
RPIA ribose 5-phosphate isomerase A -0.0066755
SUB1 SUB1 homolog (S. cerevisiae) -0.00665873
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00664973
DACH1 dachshund family transcription factor 1 -0.00664553
IL13RA2 interleukin 13 receptor, alpha 2 -0.0065755
SMAD7 SMAD family member 7 -0.00655864
MMP12 matrix metallopeptidase 12 -0.00653843
XCL1 chemokine (C motif) ligand 1 -0.00651359
PCP4 Purkinje cell protein 4 -0.00649481
CCNI cyclin I -0.00646891
SELENBP1 selenium binding protein 1 -0.00645828
SLAMF7 SLAM family member 7 -0.00643201
MBIP MAP3K12 binding inhibitory protein 1 -0.00640994
FABP1 fatty acid binding protein 1, liver -0.00638753
PODXL podocalyxin-like -0.00637898
STAT4 signal transducer and activator of transcription 4 -0.00633724
TMEM126B transmembrane protein 126B -0.00632918
ITK IL2-inducible T-cell kinase -0.00632184
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -0.0063028
IL27RA interleukin 27 receptor, alpha -0.00630245
GSTM3 glutathione S-transferase mu 3 (brain) -0.00629785
HOXA11 homeobox A11 -0.00628304
ACE2 angiotensin I converting enzyme 2 -0.00627936
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00626916
FBP1 fructose-1,6-bisphosphatase 1 -0.00625277
PLS1 plastin 1 -0.00624952
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00624583
TRH thyrotropin-releasing hormone -0.00624449
PITX3 paired-like homeodomain 3 -0.00622287
PRR5L proline rich 5 like -0.00620063
HOXA10 homeobox A10 -0.00616416
CRYBG1 crystallin beta-gamma domain containing 1 -0.00615258
AGR2 anterior gradient 2 -0.00614922
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00614684
PPAP2A phosphatidic acid phosphatase type 2A -0.00612091
VBP1 von Hippel-Lindau binding protein 1 -0.00609273
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00607315
THYN1 thymocyte nuclear protein 1 -0.00603337
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00601448
GATA6 GATA binding protein 6 -0.00600908
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00598915
FRZB frizzled-related protein -0.00594064
ODC1 ornithine decarboxylase 1 -0.00592414
ZNF140 zinc finger protein 140 -0.00592139
RPH3AL rabphilin 3A-like (without C2 domains) -0.00590837
NDC80 NDC80 kinetochore complex component -0.00590793
TPSAB1 tryptase alpha/beta 1 -0.00590241
AQP3 aquaporin 3 (Gill blood group) -0.00590085
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00589713
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.00589282
CA12 carbonic anhydrase XII -0.0058927
GATA2 GATA binding protein 2 -0.00587976
MAGEA3 melanoma antigen family A3 -0.00586617
CD2 CD2 molecule -0.00585548
REG3A regenerating islet-derived 3 alpha -0.0058498
MUC4 mucin 4, cell surface associated -0.00584047
DLX5 distal-less homeobox 5 -0.00582631
LMNB2 lamin B2 -0.00581836
COL6A2 collagen, type VI, alpha 2 -0.00578465
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -0.00578126
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00578086
SPOP speckle-type POZ protein -0.00575259
TMEM14B transmembrane protein 14B -0.00574583
SLC44A4 solute carrier family 44, member 4 -0.00569855
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -0.00569483
PFDN4 prefoldin subunit 4 -0.00569133
MRPL48 mitochondrial ribosomal protein L48 -0.005688
NKG7 natural killer cell granule protein 7 -0.00568554
CCDC88C coiled-coil domain containing 88C -0.00567893
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00566406
TMEM38B transmembrane protein 38B -0.00565128
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00564529
XK X-linked Kx blood group -0.0056355
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00563327
NSG1 neuron specific gene family member 1 -0.00562403
HOXD11 homeobox D11 -0.00562318
TRAT1 T cell receptor associated transmembrane adaptor 1 -0.00560229
CYTIP cytohesin 1 interacting protein -0.00557711
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -0.00557081
SAR1B secretion associated, Ras related GTPase 1B -0.00553347
BAG2 BCL2-associated athanogene 2 -0.00552781
AMPD1 adenosine monophosphate deaminase 1 -0.00551773
MSRB2 methionine sulfoxide reductase B2 -0.00549498
SMYD3 SET and MYND domain containing 3 -0.00548519
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00548115
SI sucrase-isomaltase (alpha-glucosidase) -0.00547081
RPL35 ribosomal protein L35 -0.00546741
CCNC cyclin C -0.00545983
CASP4 caspase 4, apoptosis-related cysteine peptidase -0.00544727
FECH ferrochelatase -0.00544556
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.00544498
ACP3 acid phosphatase 3 -0.00544421
POMZP3 POM121 and ZP3 fusion -0.00543767
WT1 Wilms tumor 1 -0.00543576
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00543104
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00540203
CLIC5 chloride intracellular channel 5 -0.00539291
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00539066
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00536354
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.00536145
F8 coagulation factor VIII, procoagulant component -0.0053598
BCL2L14 BCL2-like 14 (apoptosis facilitator) -0.00535653
BIN1 bridging integrator 1 -0.00535006
CLIC3 chloride intracellular channel 3 -0.00534073
WFDC2 WAP four-disulfide core domain 2 -0.00533602
AAMDC adipogenesis associated, Mth938 domain containing -0.00530749
PSIP1 PC4 and SFRS1 interacting protein 1 -0.00530729
DIPK1A divergent protein kinase domain 1A -0.00530038
MGP matrix Gla protein -0.00529424
MYH11 myosin, heavy chain 11, smooth muscle -0.00528973
SORD sorbitol dehydrogenase -0.00527596
NVL nuclear VCP-like -0.00527359
DES desmin -0.00527315
TXN thioredoxin -0.00527108
ARMT1 acidic residue methyltransferase 1 -0.00525255
RPS26 ribosomal protein S26 -0.00524761
CCNG1 cyclin G1 -0.00524195
AVL9 AVL9 homolog (S. cerevisiase) -0.00523891
GEM GTP binding protein overexpressed in skeletal muscle -0.00521884
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00521751
APOL2 apolipoprotein L, 2 -0.00516504
CTSW cathepsin W -0.00516418
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -0.00515418
TPRKB TP53RK binding protein -0.00515199
FAM162A family with sequence similarity 162, member A -0.00514683
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.00513623
PAEP progestagen-associated endometrial protein -0.00513416
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00513051
RNF144A ring finger protein 144A -0.00512541
LRRC19 leucine rich repeat containing 19 -0.00512027
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00511917
TMEM106C transmembrane protein 106C -0.00511737
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -0.00511442
MMP11 matrix metallopeptidase 11 -0.00511021
IL2RG interleukin 2 receptor, gamma -0.00510616
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00509947
THOC7 THO complex 7 -0.00508711
AMD1 adenosylmethionine decarboxylase 1 -0.00508392
ATRAID all-trans retinoic acid-induced differentiation factor -0.0050797
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0050684
SOCS1 suppressor of cytokine signaling 1 -0.00505599
MEP1A meprin A, alpha (PABA peptide hydrolase) -0.00504856
ESD esterase D -0.00504293
RPL35A ribosomal protein L35a -0.00502966
STXBP6 syntaxin binding protein 6 (amisyn) -0.00502576
SIRT3 sirtuin 3 -0.00501893
OVGP1 oviductal glycoprotein 1, 120kDa -0.00501158
SOX17 SRY (sex determining region Y)-box 17 -0.00500453
KLK11 kallikrein-related peptidase 11 -0.00500269
SET SET nuclear proto-oncogene -0.00500194
FASTKD3 FAST kinase domains 3 -0.0050009
ASF1A anti-silencing function 1A histone chaperone -0.00499727
CLIC2 chloride intracellular channel 2 -0.00499119
NOX1 NADPH oxidase 1 -0.00498799
RAB6A RAB6A, member RAS oncogene family -0.00496575
UGT8 UDP glycosyltransferase 8 -0.00496446
IGFBP5 insulin-like growth factor binding protein 5 -0.00496351
HOXB13 homeobox B13 -0.00495474
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.00494991
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00494348
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00494277