| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cell division cycle 42|The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013] (NCBI Entrez Gene Database, 998) |
| External Link | https://ncbi.nlm.nih.gov/gene/998 |
| Similar Terms | |
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499 genes differentially expressed following the CDC42 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0100945 |
| PRDX2 | peroxiredoxin 2 | 0.00772412 |
| PCNA | proliferating cell nuclear antigen | 0.00730596 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00721451 |
| MAP7 | microtubule-associated protein 7 | 0.00719159 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00705916 |
| MCOLN1 | mucolipin 1 | 0.00699606 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00681258 |
| S100A4 | S100 calcium binding protein A4 | 0.00680988 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00667437 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00661258 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00659132 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00656033 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00646752 |
| RBPMS | RNA binding protein with multiple splicing | 0.0063721 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00628498 |
| RXRA | retinoid X receptor, alpha | 0.00620745 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00613747 |
| TCTA | T-cell leukemia translocation altered | 0.00608137 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00606922 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00605982 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00600694 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00594777 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00593478 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00591634 |
| PRF1 | perforin 1 (pore forming protein) | 0.00589479 |
| DST | dystonin | 0.00587598 |
| HLA-C | major histocompatibility complex, class I, C | 0.00581998 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00580617 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0058024 |
| MMP2 | matrix metallopeptidase 2 | 0.00579191 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00577513 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00577257 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00575545 |
| TBX3 | T-box 3 | 0.00572047 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00570643 |
| SEPTIN10 | septin 10 | 0.00569703 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0056759 |
| PTK2 | protein tyrosine kinase 2 | 0.00567588 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00564207 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00563158 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00554343 |
| SIK1 | salt-inducible kinase 1 | 0.0055227 |
| PROCR | protein C receptor, endothelial | 0.00550358 |
| HMG20B | high mobility group 20B | 0.00545621 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00545073 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00543823 |
| TGM2 | transglutaminase 2 | 0.00543236 |
| DAPK1 | death-associated protein kinase 1 | 0.00541614 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00539273 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00537191 |
| NEFH | neurofilament, heavy polypeptide | 0.00536907 |
| IRS2 | insulin receptor substrate 2 | 0.00535688 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00534617 |
| PMP22 | peripheral myelin protein 22 | 0.00534361 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00533034 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00529106 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00528523 |
| CUX1 | cut-like homeobox 1 | 0.00527567 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00526518 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.0052428 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.00524087 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00522176 |
| UBE3C | ubiquitin protein ligase E3C | 0.00521917 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00519371 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00517747 |
| IFI44L | interferon-induced protein 44-like | 0.0051705 |
| DIXDC1 | DIX domain containing 1 | 0.0051296 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00512355 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00510851 |
| SMAD7 | SMAD family member 7 | 0.00509134 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00508989 |
| HLA-F | major histocompatibility complex, class I, F | 0.0050882 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00507658 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 0.00505874 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.005054 |
| HLA-G | major histocompatibility complex, class I, G | 0.00504811 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00504693 |
| CCN3 | cellular communication network factor 3 | 0.00500987 |
| BSG | basigin (Ok blood group) | 0.0049842 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 0.00497549 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00497497 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00496348 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00493859 |
| RAPSN | receptor-associated protein of the synapse | 0.00493676 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0049207 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00492028 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0049046 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00489712 |
| LUM | lumican | 0.0048915 |
| FEN1 | flap structure-specific endonuclease 1 | 0.00488933 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.0048833 |
| DCLK1 | doublecortin-like kinase 1 | 0.00487516 |
| HLA-B | major histocompatibility complex, class I, B | 0.00486761 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00484775 |
| CD320 | CD320 molecule | 0.00483573 |
| TPM2 | tropomyosin 2 (beta) | 0.00482327 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00482187 |
| NKG7 | natural killer cell granule protein 7 | 0.00481654 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00480638 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00478289 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00475151 |
| IL32 | interleukin 32 | 0.00473838 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00472944 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00472739 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.00470864 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00469801 |
| RBM26 | RNA binding motif protein 26 | 0.00468864 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00468207 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00466988 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0046406 |
| CDC37 | cell division cycle 37 | 0.0046276 |
| NOTCH2NL | notch 2 N-terminal like | 0.00462422 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00461692 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00461489 |
| FRY | furry homolog (Drosophila) | 0.00461219 |
| DMPK | dystrophia myotonica-protein kinase | 0.00460073 |
| C1S | complement component 1, s subcomponent | 0.00459572 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00455821 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0045466 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | 0.00452292 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00452203 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00451592 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.00451203 |
| KRT7 | keratin 7, type II | 0.00450774 |
| MAGED1 | melanoma antigen family D1 | 0.00449011 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00448029 |
| BIN1 | bridging integrator 1 | 0.00446014 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00445683 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00444015 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00443588 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00443116 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00442786 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00441003 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00439709 |
| CDC34 | cell division cycle 34 | 0.00439468 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00438745 |
| RIN2 | Ras and Rab interactor 2 | 0.00437105 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00436822 |
| COPS7A | COP9 signalosome subunit 7A | 0.0043593 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00435637 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00434568 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | 0.00431367 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00428711 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | 0.00428698 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00427573 |
| PCLAF | PCNA clamp associated factor | 0.00425108 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00424957 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00424772 |
| ACTN4 | actinin, alpha 4 | 0.00424571 |
| ITGA7 | integrin, alpha 7 | 0.00424213 |
| ATG4B | autophagy related 4B, cysteine peptidase | 0.00424141 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00423622 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00423342 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00421549 |
| PPL | periplakin | 0.00421536 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.00421425 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00420722 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0042046 |
| IGF2R | insulin-like growth factor 2 receptor | 0.00420327 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | 0.00420252 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0041947 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00418837 |
| TOX3 | TOX high mobility group box family member 3 | 0.004182 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00417981 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00417406 |
| MX2 | MX dynamin-like GTPase 2 | 0.00417288 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00416856 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00415861 |
| MEST | mesoderm specific transcript | 0.00415099 |
| STK25 | serine/threonine kinase 25 | 0.00414073 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0041291 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00412789 |
| APOD | apolipoprotein D | 0.00411145 |
| BCHE | butyrylcholinesterase | 0.00408507 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00408357 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00408091 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.00407604 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00405716 |
| IL18 | interleukin 18 | 0.00405383 |
| AXL | AXL receptor tyrosine kinase | 0.00405368 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00404897 |
| DSTN | destrin (actin depolymerizing factor) | 0.00404854 |
| KIAA0930 | KIAA0930 | 0.00404686 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00404622 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00404601 |
| IRF9 | interferon regulatory factor 9 | 0.004028 |
| TSKU | tsukushi, small leucine rich proteoglycan | 0.00402179 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00401866 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00401584 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.0040103 |
| RHOB | ras homolog family member B | 0.00401005 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.00400889 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00399941 |
| RPL10 | ribosomal protein L10 | 0.00399882 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00399378 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0039885 |
| BAG1 | BCL2-associated athanogene | 0.00398797 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00398198 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.0039787 |
| RBM6 | RNA binding motif protein 6 | 0.00397838 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00397802 |
| GNLY | granulysin | 0.00397627 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00397414 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00397013 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.00396424 |
| KRT17 | keratin 17, type I | 0.00396315 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00396159 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00395123 |
| IL2RB | interleukin 2 receptor, beta | 0.00395052 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.00394388 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa | 0.00393573 |
| GRAMD4 | GRAM domain containing 4 | 0.00393323 |
| NUCB1 | nucleobindin 1 | 0.00392559 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00392433 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00392169 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00391966 |
| RTN2 | reticulon 2 | 0.00391209 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00391113 |
| TYMS | thymidylate synthetase | 0.00390703 |
| HDC | histidine decarboxylase | 0.00390693 |
| PRKCZ | protein kinase C, zeta | 0.0038959 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00389528 |
| DENND4C | DENN/MADD domain containing 4C | 0.00388948 |
| TSPAN13 | tetraspanin 13 | 0.00388103 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00387563 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00387263 |
| COMP | cartilage oligomeric matrix protein | 0.00386625 |
| AIM2 | absent in melanoma 2 | 0.00386389 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00386182 |
| NDNF | neuron-derived neurotrophic factor | 0.00385509 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 0.00385424 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00385368 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00385196 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00384976 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00384269 |
| SFTPC | surfactant protein C | 0.00384133 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00383954 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00383752 |
| NIT1 | nitrilase 1 | 0.0038302 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.00382906 |
| SLTM | SAFB-like, transcription modulator | 0.00382734 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.0038244 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00382342 |
| SNX1 | sorting nexin 1 | 0.00381921 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0038156 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00381485 |
| KMT5B | lysine methyltransferase 5B | 0.00380935 |
| TSPAN9 | tetraspanin 9 | 0.00378894 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC42 | cell division cycle 42 | -0.0114122 |
| PITX3 | paired-like homeodomain 3 | -0.0111783 |
| PEG3 | paternally expressed 3 | -0.0111305 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0105367 |
| ADD3 | adducin 3 (gamma) | -0.00926571 |
| S100A7 | S100 calcium binding protein A7 | -0.00912583 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00893645 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00861798 |
| AK4 | adenylate kinase 4 | -0.00851338 |
| PEG10 | paternally expressed 10 | -0.00815801 |
| TSPYL5 | TSPY-like 5 | -0.00775533 |
| MLF1 | myeloid leukemia factor 1 | -0.00751851 |
| GLOD4 | glyoxalase domain containing 4 | -0.00736141 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00727013 |
| LCN2 | lipocalin 2 | -0.00723009 |
| FCGBP | Fc fragment of IgG binding protein | -0.00722528 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00715788 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00711441 |
| CA12 | carbonic anhydrase XII | -0.00707932 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00687407 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00681369 |
| GPM6B | glycoprotein M6B | -0.00681081 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00670532 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0066951 |
| DAXX | death-domain associated protein | -0.00668748 |
| CD200 | CD200 molecule | -0.00662118 |
| SGCE | sarcoglycan, epsilon | -0.00660459 |
| HTRA1 | HtrA serine peptidase 1 | -0.00656828 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00655515 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00655096 |
| ANXA1 | annexin A1 | -0.00644799 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00644554 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00643886 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.006433 |
| RRAGD | Ras-related GTP binding D | -0.00642306 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00628545 |
| HOMER1 | homer scaffolding protein 1 | -0.00621677 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0061854 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.00617341 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -0.00615272 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00611516 |
| DEFB1 | defensin, beta 1 | -0.00610138 |
| GMFG | glia maturation factor, gamma | -0.00609557 |
| AZIN1 | antizyme inhibitor 1 | -0.00605209 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0060255 |
| STK10 | serine/threonine kinase 10 | -0.00597621 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00597493 |
| CLDN8 | claudin 8 | -0.00594847 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00588744 |
| UMOD | uromodulin | -0.00588214 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00584722 |
| MAL | mal, T-cell differentiation protein | -0.00583939 |
| RGS4 | regulator of G-protein signaling 4 | -0.00579724 |
| FABP7 | fatty acid binding protein 7, brain | -0.00576708 |
| CALB1 | calbindin 1, 28kDa | -0.00569395 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00568821 |
| CAST | calpastatin | -0.00566483 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -0.00563055 |
| FGFR4 | fibroblast growth factor receptor 4 | -0.00562178 |
| AREG | amphiregulin | -0.00561614 |
| PLPBP | pyridoxal phosphate binding protein | -0.00561529 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00560371 |
| RPL26L1 | ribosomal protein L26-like 1 | -0.00556688 |
| THBS1 | thrombospondin 1 | -0.00556597 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00556359 |
| LYPLA1 | lysophospholipase I | -0.00555733 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00555667 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -0.00554596 |
| KRT23 | keratin 23, type I | -0.00554434 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00553895 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00552242 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00550487 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00548834 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00545412 |
| H1-10 | H1.10 linker histone | -0.00540418 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00538174 |
| SRPRB | signal recognition particle receptor, B subunit | -0.00536335 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00535707 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00534419 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00532986 |
| CLDN10 | claudin 10 | -0.0053289 |
| ANK2 | ankyrin 2, neuronal | -0.00527184 |
| CTSG | cathepsin G | -0.00526579 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00526485 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0052637 |
| AHCY | adenosylhomocysteinase | -0.00525158 |
| IFT52 | intraflagellar transport 52 | -0.00522292 |
| FAM107A | family with sequence similarity 107, member A | -0.00520736 |
| MT1H | metallothionein 1H | -0.00517096 |
| CD52 | CD52 molecule | -0.00516702 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00513893 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00513576 |
| C7 | complement component 7 | -0.00511568 |
| MT1F | metallothionein 1F | -0.00510751 |
| DPEP1 | dipeptidase 1 (renal) | -0.00510636 |
| KRT5 | keratin 5, type II | -0.00510283 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | -0.00503626 |
| CHPT1 | choline phosphotransferase 1 | -0.00501708 |
| LXN | latexin | -0.00496878 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00496867 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00496146 |
| ALB | albumin | -0.00494708 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0049298 |
| TYRP1 | tyrosinase-related protein 1 | -0.00490933 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00490587 |
| GCH1 | GTP cyclohydrolase 1 | -0.0048839 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00483306 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00481223 |
| BCAS2 | breast carcinoma amplified sequence 2 | -0.00480387 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00474989 |
| SORT1 | sortilin 1 | -0.00473623 |
| ASRGL1 | asparaginase like 1 | -0.00471999 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00471743 |
| MT2A | metallothionein 2A | -0.00469735 |
| SELL | selectin L | -0.00469612 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00469226 |
| LEFTY1 | left-right determination factor 1 | -0.00468831 |
| KRT19 | keratin 19, type I | -0.00467077 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0046466 |
| EFHD1 | EF-hand domain family, member D1 | -0.00464249 |
| SST | somatostatin | -0.00463287 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00463278 |
| COLEC11 | collectin sub-family member 11 | -0.00462372 |
| TFRC | transferrin receptor | -0.00462339 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00461418 |
| NPTX2 | neuronal pentraxin II | -0.00460897 |
| IL6ST | interleukin 6 signal transducer | -0.00460701 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00459326 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00458778 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0045799 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00456914 |
| DOK5 | docking protein 5 | -0.00455513 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 | -0.00454788 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00451874 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00450613 |
| FZD6 | frizzled class receptor 6 | -0.00450248 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00449843 |
| TSNAX | translin-associated factor X | -0.00449387 |
| TCF21 | transcription factor 21 | -0.00448405 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00447375 |
| RGCC | regulator of cell cycle | -0.00446882 |
| PROM1 | prominin 1 | -0.00446086 |
| RPA3 | replication protein A3, 14kDa | -0.00445517 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00444672 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00443454 |
| MPO | myeloperoxidase | -0.00442998 |
| MPC1 | mitochondrial pyruvate carrier 1 | -0.00442932 |
| ANGPT2 | angiopoietin 2 | -0.00442412 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00441322 |
| EAPP | E2F-associated phosphoprotein | -0.00441299 |
| FOXG1 | forkhead box G1 | -0.0044083 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.00440392 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -0.00439733 |
| BTG3 | BTG family, member 3 | -0.00438657 |
| RCAN1 | regulator of calcineurin 1 | -0.00438225 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00438135 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.00436745 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00436502 |
| MRPL19 | mitochondrial ribosomal protein L19 | -0.00435983 |
| ATF3 | activating transcription factor 3 | -0.0043569 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00435505 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0043486 |
| KLF2 | Kruppel-like factor 2 | -0.00432614 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00432103 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.0043182 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -0.00431608 |
| RGS10 | regulator of G-protein signaling 10 | -0.00431478 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | -0.00431053 |
| KRT81 | keratin 81, type II | -0.00430856 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | -0.00429981 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00429536 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00428771 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 | -0.00428639 |
| CLTB | clathrin, light chain B | -0.00428353 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0042816 |
| NUP93 | nucleoporin 93kDa | -0.00427491 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00426073 |
| CLDN7 | claudin 7 | -0.00425787 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00425179 |
| PRKCA | protein kinase C, alpha | -0.00424949 |
| SET | SET nuclear proto-oncogene | -0.00424565 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00424555 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00423881 |
| BPI | bactericidal/permeability-increasing protein | -0.00423788 |
| PLLP | plasmolipin | -0.00423377 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00423362 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00422489 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00421831 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00421328 |
| PLK1 | polo-like kinase 1 | -0.00420764 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00420622 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.0042013 |
| EVI2A | ecotropic viral integration site 2A | -0.00420037 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00418619 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00418333 |
| LY75 | lymphocyte antigen 75 | -0.00417432 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00416139 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00415817 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00415625 |
| MGP | matrix Gla protein | -0.00415211 |
| PRKCQ | protein kinase C, theta | -0.00414737 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00413522 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00413273 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | -0.00412709 |
| ZFAND1 | zinc finger, AN1-type domain 1 | -0.00411977 |
| TMEM38B | transmembrane protein 38B | -0.00411927 |
| PMP2 | peripheral myelin protein 2 | -0.0041144 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00411408 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.00411238 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00410666 |
| KLK10 | kallikrein-related peptidase 10 | -0.00409256 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00408019 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00407914 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00407687 |
| CCNI | cyclin I | -0.00406276 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.0040555 |
| BCL10 | B-cell CLL/lymphoma 10 | -0.00405398 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00404449 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00402293 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00402288 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00402172 |
| LCMT1 | leucine carboxyl methyltransferase 1 | -0.00400774 |
| PODXL | podocalyxin-like | -0.00400236 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00400135 |
| DPH5 | diphthamide biosynthesis 5 | -0.00398957 |
| PLAT | plasminogen activator, tissue | -0.00397286 |
| KRT15 | keratin 15, type I | -0.00396772 |
| RIOX2 | ribosomal oxygenase 2 | -0.00396607 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00394981 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00394858 |
| NGRN | neugrin, neurite outgrowth associated | -0.00394744 |
| ATG3 | autophagy related 3 | -0.00394643 |
| SLC22A8 | solute carrier family 22 (organic anion transporter), member 8 | -0.00394369 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00392824 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00392551 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00391867 |
| ANXA6 | annexin A6 | -0.00391855 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00391616 |
| PARL | presenilin associated, rhomboid-like | -0.00391168 |
| MT1G | metallothionein 1G | -0.00390878 |
| RIMBP2 | RIMS binding protein 2 | -0.00390629 |
| ADM | adrenomedullin | -0.00390201 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00389428 |
| CLC | Charcot-Leyden crystal galectin | -0.00389212 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00389089 |
| CCNH | cyclin H | -0.0038888 |
| OLFML3 | olfactomedin-like 3 | -0.00388528 |
| LYRM1 | LYR motif containing 1 | -0.00388412 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00387348 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00386164 |
