CDC42BPA Gene Set

Dataset KEA Substrates of Kinases
Category physical interactions
Type kinase
Description CDC42 binding protein kinase alpha (DMPK-like)|The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8476)
External Link http://www.ncbi.nlm.nih.gov/gene/8476
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Genes

12 substrates of the kinase CDC42BPA from the curated KEA Substrates of Kinases dataset.

Symbol Name
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CDC25B cell division cycle 25B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CIITA class II, major histocompatibility complex, transactivator
IL1R1 interleukin 1 receptor, type I
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL9 myosin, light chain 9, regulatory
PPP1R12C protein phosphatase 1, regulatory subunit 12C
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM2 serine/arginine repetitive matrix 2