| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CDC42 binding protein kinase alpha (DMPK-like)|The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8476) |
| External Link | https://ncbi.nlm.nih.gov/gene/8476 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CDC42BPA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | 0.0172023 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0157287 |
| MAP7 | microtubule-associated protein 7 | 0.0154936 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0132624 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0117218 |
| PDGFC | platelet derived growth factor C | 0.0114809 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0109386 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0108628 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0108151 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0106619 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0103731 |
| FN1 | fibronectin 1 | 0.0102847 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00988719 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00975732 |
| CLU | clusterin | 0.00952376 |
| RGS1 | regulator of G-protein signaling 1 | 0.00920814 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00918473 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00915458 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00906406 |
| THBS1 | thrombospondin 1 | 0.00898613 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00888062 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00870274 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00868669 |
| EHF | ets homologous factor | 0.00860081 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00855336 |
| RIN2 | Ras and Rab interactor 2 | 0.00846184 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00837351 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00836501 |
| JAG1 | jagged 1 | 0.00831762 |
| S100P | S100 calcium binding protein P | 0.00819897 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00800298 |
| TNS3 | tensin 3 | 0.00795559 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.007798 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00779624 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00777745 |
| TMEM106B | transmembrane protein 106B | 0.00776419 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00775568 |
| CHKB | choline kinase beta | 0.00769392 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00769078 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00768584 |
| IL18 | interleukin 18 | 0.00764277 |
| PON2 | paraoxonase 2 | 0.00762034 |
| HTRA1 | HtrA serine peptidase 1 | 0.00757676 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00752243 |
| TARP | TCR gamma alternate reading frame protein | 0.00751964 |
| TFEC | transcription factor EC | 0.00745335 |
| SIK1 | salt-inducible kinase 1 | 0.00742465 |
| ANOS1 | anosmin 1 | 0.00737241 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00735284 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00731567 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00730737 |
| MSR1 | macrophage scavenger receptor 1 | 0.00728916 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0072739 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00727126 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.00723455 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.00719391 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00713859 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.0071188 |
| ADIRF | adipogenesis regulatory factor | 0.00709036 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00708337 |
| TOX3 | TOX high mobility group box family member 3 | 0.00706354 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00705829 |
| GPX1 | glutathione peroxidase 1 | 0.00705565 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.0069685 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 0.00692962 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00690081 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00688729 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00687328 |
| SNAI2 | snail family zinc finger 2 | 0.0068729 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.00683153 |
| LXN | latexin | 0.00682378 |
| RPA3 | replication protein A3, 14kDa | 0.0067824 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00676202 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00672873 |
| TSPAN13 | tetraspanin 13 | 0.00671899 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00670811 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00667868 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0066775 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00667011 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00662895 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00661788 |
| CLGN | calmegin | 0.00659949 |
| PFN2 | profilin 2 | 0.00655294 |
| MSMB | microseminoprotein, beta- | 0.00654466 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00653369 |
| INTS6 | integrator complex subunit 6 | 0.00653294 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.00651598 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00650452 |
| KRT7 | keratin 7, type II | 0.00648062 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00646954 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.00646456 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00646052 |
| RPS5 | ribosomal protein S5 | 0.00643075 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00638403 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00637386 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00636941 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.00635754 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.00633582 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00633016 |
| TIPRL | TOR signaling pathway regulator | 0.00632951 |
| SORT1 | sortilin 1 | 0.00632336 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00630602 |
| MRTFB | myocardin related transcription factor B | 0.00630336 |
| COMMD3 | COMM domain containing 3 | 0.0062891 |
| PRDX4 | peroxiredoxin 4 | 0.00627099 |
| DMXL2 | Dmx-like 2 | 0.00625486 |
| MAGEA3 | melanoma antigen family A3 | 0.00624799 |
| TSPAN7 | tetraspanin 7 | 0.00624773 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00624233 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00622409 |
| APOC1 | apolipoprotein C-I | 0.00621649 |
| ZNF512B | zinc finger protein 512B | 0.00620723 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00616568 |
| RAD51C | RAD51 paralog C | 0.00615847 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00611036 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00609345 |
| PCTP | phosphatidylcholine transfer protein | 0.00608811 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00607581 |
| CD86 | CD86 molecule | 0.00607067 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0060527 |
| LYPLA1 | lysophospholipase I | 0.0060519 |
| VCL | vinculin | 0.00603761 |
| EVI2A | ecotropic viral integration site 2A | 0.00602597 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.0060173 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00601189 |
| SHTN1 | shootin 1 | 0.0060071 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.00599914 |
| COG7 | component of oligomeric golgi complex 7 | 0.00599469 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00598743 |
| COMMD10 | COMM domain containing 10 | 0.00595471 |
| PTK2 | protein tyrosine kinase 2 | 0.00594795 |
| CST7 | cystatin F (leukocystatin) | 0.0059462 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00594096 |
| EGR2 | early growth response 2 | 0.00589004 |
| GPR65 | G protein-coupled receptor 65 | 0.00587626 |
| CLEC4A | C-type lectin domain family 4, member A | 0.00586478 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00585474 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00584966 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00584465 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00584391 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00582541 |
| NUP43 | nucleoporin 43kDa | 0.00580849 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00579655 |
| BCL2A1 | BCL2-related protein A1 | 0.00577121 |
| STAB1 | stabilin 1 | 0.00575988 |
| SEC24A | SEC24 family member A | 0.00575807 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00575085 |
| HLTF | helicase-like transcription factor | 0.00574501 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00574404 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00574267 |
| AHR | aryl hydrocarbon receptor | 0.00573967 |
| TMEM50B | transmembrane protein 50B | 0.00573937 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00567949 |
| LOXL1 | lysyl oxidase-like 1 | 0.00566898 |
| CTSK | cathepsin K | 0.00565057 |
| EPHA4 | EPH receptor A4 | 0.00564315 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00563746 |
| PRKCZ | protein kinase C, zeta | 0.00563521 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00559538 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00556198 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.0055581 |
| PEX11B | peroxisomal biogenesis factor 11 beta | 0.00549918 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00549373 |
| KIFAP3 | kinesin-associated protein 3 | 0.00548664 |
| RFK | riboflavin kinase | 0.00547286 |
| SLA | Src-like-adaptor | 0.00546976 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00546467 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00546387 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00545668 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00545215 |
| CCNA2 | cyclin A2 | 0.00544518 |
| FYB1 | FYN binding protein 1 | 0.00542264 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0054209 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00541422 |
| BTBD1 | BTB (POZ) domain containing 1 | 0.005413 |
| LRRC15 | leucine rich repeat containing 15 | 0.00540325 |
| POGK | pogo transposable element with KRAB domain | 0.00538372 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00535319 |
| COPS4 | COP9 signalosome subunit 4 | 0.00533229 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00532829 |
| AVPI1 | arginine vasopressin-induced 1 | 0.00532083 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.00531281 |
| FPR1 | formyl peptide receptor 1 | 0.0053079 |
| NGRN | neugrin, neurite outgrowth associated | 0.00529529 |
| C5AR1 | complement component 5a receptor 1 | 0.00529326 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0052827 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00526088 |
| LTF | lactotransferrin | 0.00524652 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00524195 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.00523903 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00523878 |
| REEP5 | receptor accessory protein 5 | 0.00523425 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.00522723 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00522626 |
| SMAD6 | SMAD family member 6 | 0.0052154 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00521523 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00520872 |
| DAPK1 | death-associated protein kinase 1 | 0.00519308 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00518217 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00517969 |
| OAZ3 | ornithine decarboxylase antizyme 3 | 0.00517201 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00515741 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | 0.00515034 |
| TMEM165 | transmembrane protein 165 | 0.00514439 |
| ANXA10 | annexin A10 | 0.00512561 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00512115 |
| TMEM230 | transmembrane protein 230 | 0.00512072 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.00511741 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00511078 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00510143 |
| HHEX | hematopoietically expressed homeobox | 0.00509658 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.005096 |
| SGCE | sarcoglycan, epsilon | 0.00508998 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00508913 |
| KIAA1109 | KIAA1109 | 0.00508912 |
| RDX | radixin | 0.00508854 |
| FAM46C | family with sequence similarity 46, member C | 0.00508628 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.00507796 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00506495 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00506288 |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 | 0.00506124 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00505496 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00504957 |
| LRRC17 | leucine rich repeat containing 17 | 0.00504752 |
| SELE | selectin E | 0.00503907 |
| LAGE3 | L antigen family, member 3 | 0.0050365 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00503547 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00503523 |
| COG5 | component of oligomeric golgi complex 5 | 0.00502959 |
| VEGFC | vascular endothelial growth factor C | 0.00502461 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00501706 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.0050136 |
| HOPX | HOP homeobox | 0.0050114 |
| ODC1 | ornithine decarboxylase 1 | 0.00500955 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00500908 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 0.00500088 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0049997 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00499361 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00498968 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.00498883 |
| USP48 | ubiquitin specific peptidase 48 | 0.00498028 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00497866 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0049785 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00497602 |
| C1RL | complement component 1, r subcomponent-like | 0.00497354 |
| PLXNC1 | plexin C1 | 0.00497251 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.00496133 |
| IQCG | IQ motif containing G | 0.00495019 |
| CREBL2 | cAMP responsive element binding protein-like 2 | 0.00495018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MX1 | MX dynamin-like GTPase 1 | -0.0208099 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0162224 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0140972 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0139662 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0127964 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0115517 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0115291 |
| IFI44L | interferon-induced protein 44-like | -0.0114636 |
| IFI44 | interferon-induced protein 44 | -0.0113261 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0112128 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0110637 |
| HOXC6 | homeobox C6 | -0.0107675 |
| CLTB | clathrin, light chain B | -0.010421 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0104079 |
| CA12 | carbonic anhydrase XII | -0.0103519 |
| MX2 | MX dynamin-like GTPase 2 | -0.0103514 |
| RTN2 | reticulon 2 | -0.0102347 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00997398 |
| STC1 | stanniocalcin 1 | -0.00979237 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0097693 |
| CRYAB | crystallin, alpha B | -0.00967622 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00959868 |
| REG1A | regenerating islet-derived 1 alpha | -0.00949961 |
| MGLL | monoglyceride lipase | -0.00936228 |
| TFF1 | trefoil factor 1 | -0.00931345 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00922127 |
| OLFML3 | olfactomedin-like 3 | -0.00915635 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00911826 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00906944 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00898243 |
| APOD | apolipoprotein D | -0.00895645 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00883771 |
| AOC1 | amine oxidase, copper containing 1 | -0.00882025 |
| BEX1 | brain expressed, X-linked 1 | -0.00877391 |
| ASS1 | argininosuccinate synthase 1 | -0.00875866 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00858821 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00855039 |
| XAF1 | XIAP associated factor 1 | -0.00855037 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00846928 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00825534 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00824016 |
| USP18 | ubiquitin specific peptidase 18 | -0.0082154 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00819333 |
| KLK11 | kallikrein-related peptidase 11 | -0.00816248 |
| KLK10 | kallikrein-related peptidase 10 | -0.00815591 |
| MT1X | metallothionein 1X | -0.00814849 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0081473 |
| POSTN | periostin, osteoblast specific factor | -0.00806955 |
| NES | nestin | -0.0080256 |
| LCN2 | lipocalin 2 | -0.00802007 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00801063 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00799742 |
| VSNL1 | visinin-like 1 | -0.00794915 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00788352 |
| CALB1 | calbindin 1, 28kDa | -0.00783046 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00777373 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00777244 |
| SPON2 | spondin 2, extracellular matrix protein | -0.0077415 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00770277 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00767475 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.007667 |
| HLA-B | major histocompatibility complex, class I, B | -0.00764598 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00763321 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00763181 |
| FADS3 | fatty acid desaturase 3 | -0.00762398 |
| RHCG | Rh family, C glycoprotein | -0.00761552 |
| DPEP1 | dipeptidase 1 (renal) | -0.00760692 |
| S100A7 | S100 calcium binding protein A7 | -0.00758112 |
| CHGB | chromogranin B | -0.0075682 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0075604 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00755152 |
| SDC2 | syndecan 2 | -0.00751299 |
| MGP | matrix Gla protein | -0.00748703 |
| DSG3 | desmoglein 3 | -0.00748383 |
| NTS | neurotensin | -0.00739532 |
| OPHN1 | oligophrenin 1 | -0.00739492 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00736285 |
| JUND | jun D proto-oncogene | -0.00732409 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00731092 |
| INSR | insulin receptor | -0.0073108 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00729723 |
| TPBG | trophoblast glycoprotein | -0.00729361 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00727003 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.0072601 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00722847 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00718888 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00718189 |
| PDZK1 | PDZ domain containing 1 | -0.00713548 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00712303 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00710755 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00710209 |
| TCTN2 | tectonic family member 2 | -0.00707728 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00707017 |
| XIC | X chromosome inactivation center | -0.00704492 |
| TMEM176B | transmembrane protein 176B | -0.0070341 |
| HOMER2 | homer scaffolding protein 2 | -0.00701711 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0069951 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00697957 |
| CALML3 | calmodulin-like 3 | -0.00695441 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0069399 |
| WNT4 | wingless-type MMTV integration site family, member 4 | -0.00693595 |
| PLK1 | polo-like kinase 1 | -0.0069164 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00686126 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0068569 |
| GPC3 | glypican 3 | -0.00679508 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00678838 |
| SPRR2B | small proline-rich protein 2B | -0.00676894 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00675223 |
| ANXA9 | annexin A9 | -0.00674246 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0067424 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00672664 |
| SPRR1A | small proline-rich protein 1A | -0.00672545 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00672315 |
| HLA-C | major histocompatibility complex, class I, C | -0.00669275 |
| KLK13 | kallikrein-related peptidase 13 | -0.00666135 |
| DES | desmin | -0.00666113 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00664722 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00662704 |
| EDN3 | endothelin 3 | -0.00657682 |
| EPHX3 | epoxide hydrolase 3 | -0.00655394 |
| MT1H | metallothionein 1H | -0.0065456 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00653667 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.0064768 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00647544 |
| PENK | proenkephalin | -0.00647216 |
| REG3A | regenerating islet-derived 3 alpha | -0.00641865 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0064039 |
| CFI | complement factor I | -0.00638408 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00637212 |
| TMEM176A | transmembrane protein 176A | -0.00637059 |
| EDNRB | endothelin receptor type B | -0.00636543 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00635529 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00633173 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00631107 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00631055 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00630679 |
| ANGPTL4 | angiopoietin-like 4 | -0.00630366 |
| MAB21L1 | mab-21-like 1 (C. elegans) | -0.00629468 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00625687 |
| DUOX2 | dual oxidase 2 | -0.00625052 |
| AACS | acetoacetyl-CoA synthetase | -0.00625032 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00624822 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00623952 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00622123 |
| CHRDL1 | chordin-like 1 | -0.00621314 |
| STMN2 | stathmin 2 | -0.00620367 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00620149 |
| HLA-F | major histocompatibility complex, class I, F | -0.0061691 |
| ALB | albumin | -0.00612976 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00612715 |
| TAOK3 | TAO kinase 3 | -0.00612103 |
| BCL7A | B-cell CLL/lymphoma 7A | -0.006117 |
| RET | ret proto-oncogene | -0.00611661 |
| CALB2 | calbindin 2 | -0.00609824 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.00608703 |
| VPREB3 | pre-B lymphocyte 3 | -0.00608613 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0060759 |
| KRT15 | keratin 15, type I | -0.00604573 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00602544 |
| IRF9 | interferon regulatory factor 9 | -0.00602242 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00602068 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00601926 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00601186 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00596753 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00595658 |
| SPRR1B | small proline-rich protein 1B | -0.00595569 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0059528 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00593343 |
| REG1B | regenerating islet-derived 1 beta | -0.00591547 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00591517 |
| SMAGP | small cell adhesion glycoprotein | -0.00589405 |
| DSG1 | desmoglein 1 | -0.0058907 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00588776 |
| NEFM | neurofilament, medium polypeptide | -0.0058761 |
| KRT1 | keratin 1, type II | -0.00586273 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00584925 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -0.00582324 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00581944 |
| ERP29 | endoplasmic reticulum protein 29 | -0.00579975 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00579975 |
| IRF7 | interferon regulatory factor 7 | -0.0057527 |
| THBS4 | thrombospondin 4 | -0.00574559 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00574499 |
| MVP | major vault protein | -0.00573958 |
| EPS8L1 | EPS8-like 1 | -0.00569823 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00569643 |
| YBX3 | Y box binding protein 3 | -0.00569591 |
| ADM | adrenomedullin | -0.00568847 |
| GAB2 | GRB2-associated binding protein 2 | -0.00568505 |
| TAC1 | tachykinin, precursor 1 | -0.00567739 |
| INAVA | innate immunity activator | -0.00567611 |
| S100A10 | S100 calcium binding protein A10 | -0.00566779 |
| NDRG1 | N-myc downstream regulated 1 | -0.00566747 |
| MEN1 | multiple endocrine neoplasia I | -0.00566706 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00564851 |
| MMP3 | matrix metallopeptidase 3 | -0.00561349 |
| TWF2 | twinfilin actin binding protein 2 | -0.00561204 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00560971 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00559049 |
| SLC35G2 | solute carrier family 35, member G2 | -0.00557862 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00557491 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | -0.00557229 |
| FAM102A | family with sequence similarity 102, member A | -0.00556273 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00554986 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00553795 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.00553192 |
| NREP | neuronal regeneration related protein | -0.00552949 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00551484 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0055116 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00549907 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00549764 |
| DEFB4A | defensin, beta 4A | -0.00545165 |
| MT1E | metallothionein 1E | -0.00543929 |
| MATN2 | matrilin 2 | -0.0054268 |
| TLCD3A | TLC domain containing 3A | -0.00541758 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00541213 |
| KRT2 | keratin 2, type II | -0.00540839 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00540157 |
| COL1A2 | collagen, type I, alpha 2 | -0.0054013 |
| SSBP3 | single stranded DNA binding protein 3 | -0.00539116 |
| JADE2 | jade family PHD finger 2 | -0.00538315 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00536525 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.00535187 |
| WIF1 | WNT inhibitory factor 1 | -0.00533964 |
| TMPRSS11D | transmembrane protease, serine 11D | -0.00533808 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00532735 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00532211 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00531428 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00530871 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00530021 |
| LAMA4 | laminin, alpha 4 | -0.0052928 |
| CD1E | CD1e molecule | -0.00528978 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | -0.00528151 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00527498 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00527194 |
| FGF9 | fibroblast growth factor 9 | -0.00525936 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00525564 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.00525216 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00524706 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00522539 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00521779 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00520439 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00520247 |
| RELN | reelin | -0.00518521 |
| CALR | calreticulin | -0.00518436 |
| TMEM132A | transmembrane protein 132A | -0.00517145 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00516504 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00515799 |
| RETREG1 | reticulophagy regulator 1 | -0.00515083 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00515061 |
