CDC42BPA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CDC42 binding protein kinase alpha (DMPK-like)|The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8476)
External Link http://www.ncbi.nlm.nih.gov/gene/8476
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Genes

59 interacting proteins for CDC42BPA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
AURKA aurora kinase A
AURKB aurora kinase B
BMP2K BMP2 inducible kinase
BRD3 bromodomain containing 3
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDC42 cell division cycle 42
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDK2 cyclin-dependent kinase 2
CDK9 cyclin-dependent kinase 9
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
EPHA7 EPH receptor A7
FER fer (fps/fes related) tyrosine kinase
GAK cyclin G associated kinase
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HCK HCK proto-oncogene, Src family tyrosine kinase
IGF1R insulin-like growth factor 1 receptor
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INSR insulin receptor
JAK1 Janus kinase 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL9 myosin, light chain 9, regulatory
MYO18A myosin XVIIIA
NEK9 NIMA-related kinase 9
PDPK1 3-phosphoinositide dependent protein kinase 1
PLK4 polo-like kinase 4
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTK2 protein tyrosine kinase 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RHOQ ras homolog family member Q
SIK3 SIK family kinase 3
SNAPIN SNAP-associated protein
SPEG SPEG complex locus
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK16 serine/threonine kinase 16
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBK1 TANK-binding kinase 1
TEC tec protein tyrosine kinase
TNK1 tyrosine kinase, non-receptor, 1
TYK2 tyrosine kinase 2
UBC ubiquitin C
ULK3 unc-51 like kinase 3
WEE1 WEE1 G2 checkpoint kinase
YES1 YES proto-oncogene 1, Src family tyrosine kinase