|Dataset||Pathway Commons Protein-Protein Interactions|
|Description||CDC42 effector protein (Rho GTPase binding) 2|CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 10435)|
|Downloads & Tools|
5 interacting proteins for CDC42EP2 from the Pathway Commons Protein-Protein Interactions dataset.