CDC42EP4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CDC42 effector protein (Rho GTPase binding) 4|The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23580)
External Link http://www.ncbi.nlm.nih.gov/gene/23580
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13 interacting proteins for CDC42EP4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
CDC42 cell division cycle 42
ELAVL1 ELAV like RNA binding protein 1
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
NRF1 nuclear respiratory factor 1
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
RHOQ ras homolog family member Q
SRPK1 SRSF protein kinase 1
SRPK2 SRSF protein kinase 2
TGFBR1 transforming growth factor, beta receptor 1
UBC ubiquitin C
VCP valosin containing protein
WDR6 WD repeat domain 6