CDC6 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description cell division cycle 6|The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 990)
Similar Terms
Downloads & Tools

Genes

657 genes differentially expressed following the CDC6 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
AKAP6 A kinase (PRKA) anchor protein 6 2.69346
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.69346
CORT cortistatin 2.69346
RELT RELT tumor necrosis factor receptor 2.69346
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.69346
GPR108 G protein-coupled receptor 108 2.69346
NOMO1 NODAL modulator 1 2.69346
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 2.69346
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.69346
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 2.69346
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.69346
KIFC2 kinesin family member C2 2.69346
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 2.69346
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 2.69346
WDR91 WD repeat domain 91 2.69346
PHF19 PHD finger protein 19 2.69346
CLEC4A C-type lectin domain family 4, member A 2.69346
BMP4 bone morphogenetic protein 4 2.69346
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 2.69346
NEK8 NIMA-related kinase 8 2.69346
NGB neuroglobin 2.69346
BAG3 BCL2-associated athanogene 3 2.69346
ZNF432 zinc finger protein 432 2.69346
IL12RB2 interleukin 12 receptor, beta 2 2.69346
PROKR2 prokineticin receptor 2 2.69346
EGFL8 EGF-like-domain, multiple 8 2.69346
PLIN4 perilipin 4 2.69346
TVP23A trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) 2.69346
CXCL17 chemokine (C-X-C motif) ligand 17 2.69346
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.69346
GAA glucosidase, alpha; acid 2.69346
TAC3 tachykinin 3 2.69346
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.69346
TPK1 thiamin pyrophosphokinase 1 2.69346
C19ORF47 chromosome 19 open reading frame 47 2.69346
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2.69346
UNC79 unc-79 homolog (C. elegans) 2.69346
HFE hemochromatosis 2.69346
MEIKIN meiotic kinetochore factor 2.69346
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.69346
CAPG capping protein (actin filament), gelsolin-like 2.69346
ZNF354A zinc finger protein 354A 2.69346
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 2.69346
PDE4C phosphodiesterase 4C, cAMP-specific 2.69346
ZBTB7B zinc finger and BTB domain containing 7B 2.69346
TUBGCP6 tubulin, gamma complex associated protein 6 2.69346
RUMY4 RUMY family member 4 2.57379
CD200R1L CD200 receptor 1-like 2.57379
ZFP37 ZFP37 zinc finger protein 2.57379
MADD MAP-kinase activating death domain 2.57379
ADGRE2 adhesion G protein-coupled receptor E2 2.57379
PI15 peptidase inhibitor 15 2.57379
SLC44A4 solute carrier family 44, member 4 2.57379
TREML2 triggering receptor expressed on myeloid cells-like 2 2.57379
NXPH3 neurexophilin 3 2.57379
TINAGL1 tubulointerstitial nephritis antigen-like 1 2.57379
NPIPA2 nuclear pore complex interacting protein family, member A2 2.57379
BTC betacellulin 2.57379
MRO maestro 2.57379
MAGEA3 melanoma antigen family A3 2.57379
OR2A42 olfactory receptor, family 2, subfamily A, member 42 2.57379
SLC26A3 solute carrier family 26 (anion exchanger), member 3 2.57379
ZNF491 zinc finger protein 491 2.57379
CFAP74 cilia and flagella associated protein 74 2.57379
ZNF18 zinc finger protein 18 2.57379
TSLIG1 tRNA splicing ligase complex subunit 1 2.57379
NOTO notochord homeobox 2.57379
ADTRP androgen-dependent TFPI-regulating protein 2.57379
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.57379
TXLNB taxilin beta 2.57379
MED25 mediator complex subunit 25 2.57379
ZBTB9 zinc finger and BTB domain containing 9 2.57379
HYPK huntingtin interacting protein K 2.57379
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.57379
BGLAP bone gamma-carboxyglutamate (gla) protein 2.57379
FGD3 FYVE, RhoGEF and PH domain containing 3 2.57379
RPH3AL rabphilin 3A-like (without C2 domains) 2.57379
CILP2 cartilage intermediate layer protein 2 2.57379
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 2.57379
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.57379
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.57379
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.57379
TMEM240 transmembrane protein 240 2.57379
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.57379
OLIG1 oligodendrocyte transcription factor 1 2.57379
COL8A2 collagen, type VIII, alpha 2 2.57379
CD164L2 CD164 sialomucin-like 2 2.57379
PER2 period circadian clock 2 2.57379
EFNA3 ephrin-A3 2.57379
ORAI1 ORAI calcium release-activated calcium modulator 1 2.57379
ZNF611 zinc finger protein 611 2.57379
ZSCAN25 zinc finger and SCAN domain containing 25 2.57379
FAM194C family with sequence similarity 149 member C 2.57379
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 2.57379
SNX5 sorting nexin 5 2.57379
CA4 carbonic anhydrase IV 2.57379
SFXN3 sideroflexin 3 2.57379
FBLN5 fibulin 5 2.57379
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.57379
ARSD arylsulfatase D 2.57379
TRIL TLR4 interactor with leucine-rich repeats 2.57379
ARHGAP33 Rho GTPase activating protein 33 2.57379
ARRDC4 arrestin domain containing 4 2.57379
LYST lysosomal trafficking regulator 2.57379
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.57379
TMEM151A transmembrane protein 151A 2.57379
PDLIM4 PDZ and LIM domain 4 2.57379
PNMA2 paraneoplastic Ma antigen 2 2.57379
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 2.57379
PKD1L3 polycystic kidney disease 1-like 3 2.57379
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.57379
RASA4B RAS p21 protein activator 4B 2.57379
CR2 complement component (3d/Epstein Barr virus) receptor 2 2.57379
SLC25A45 solute carrier family 25, member 45 2.57379
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.57379
GSTM4 glutathione S-transferase mu 4 2.57379
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 2.57379
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 2.57379
CUBN cubilin (intrinsic factor-cobalamin receptor) 2.57379
HEPH hephaestin 2.57379
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2.57379
TRIM38 tripartite motif containing 38 2.57379
TNNC1 troponin C type 1 (slow) 2.57379
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.57379
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 2.57379
CLDN15 claudin 15 2.57379
FKBP9 FK506 binding protein 9, 63 kDa 2.57379
OTOA otoancorin 2.57379
OTOG otogelin 2.57379
RIPOR1 RHO family interacting cell polarization regulator 1 2.57379
MIX23 mitochondrial matrix import factor 23 2.57379
HTRA2 HtrA serine peptidase 2 2.57379
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.57379
ELOVL2 ELOVL fatty acid elongase 2 2.57379
NEURL2 neuralized E3 ubiquitin protein ligase 2 2.57379
PROX1 prospero homeobox 1 2.57379
TFF3 trefoil factor 3 (intestinal) 2.57379
LMNTD2 lamin tail domain containing 2 2.57379
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2.57379
FMO3 flavin containing monooxygenase 3 2.57379
SRGN serglycin 2.57379
KRT86 keratin 86, type II 2.57379
MNMIP1 manchette microtubule inner protein 1 2.57379
ODAD1 outer dynein arm docking complex subunit 1 2.57379
SEPTIN4 septin 4 2.57379
TEKTIP1 tektin bundle interacting protein 1 2.57379
GARIN1B golgi associated RAB2 interactor 1B 2.57379
TAFA1 TAFA chemokine like family member 1 2.57379
SHISAL2A shisa like 2A 2.57379
C10ORF143 chromosome 10 open reading frame 143 2.57379
MSANTD7 Myb/SANT DNA binding domain containing 7 2.57379
IL6ST-DT IL6ST divergent transcript 2.57379
EPCIP exosomal polycystin 1 interacting protein 2.57379
SPMIP2 sperm microtubule inner protein 2 2.57379
CFAP100 cilia and flagella associated protein 100 2.57379
TRMT9B tRNA methyltransferase 9B (putative) 2.57379
CCDC191 coiled-coil domain containing 191 2.57379
TSPOAP1 TSPO associated protein 1 2.57379
TEPSIN TEPSIN adaptor related protein complex 4 accessory protein 2.57379
SMIM36 small integral membrane protein 36 2.57379
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 2.57379
STUM stum, mechanosensory transduction mediator homolog 2.57379
BBOF1 basal body orientation factor 1 2.57379
LRATD1 LRAT domain containing 1 2.57379
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 2.57379
DNAI4 dynein axonemal intermediate chain 4 2.57379
KRABD3 KRAB domain containing 3 2.57379
COL4A4 collagen, type IV, alpha 4 2.57379
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) 2.57379
TRIM69 tripartite motif containing 69 2.57379
PPP1R42 protein phosphatase 1, regulatory subunit 42 2.57379
TSGA10IP testis specific, 10 interacting protein 2.57379
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 2.57379
BBS2 Bardet-Biedl syndrome 2 2.57379
PRADC1 protease-associated domain containing 1 2.57379
MFSD2B major facilitator superfamily domain containing 2B 2.57379
C3ORF80 chromosome 3 open reading frame 80 2.57379
TUBA3D tubulin, alpha 3d 2.57379
TSSC4 tumor suppressing subtransferable candidate 4 2.57379
MTNR1A melatonin receptor 1A 2.57379
MEI4 meiosis-specific 4 homolog (S. cerevisiae) 2.57379
GJA9 gap junction protein, alpha 9, 59kDa 2.57379
TAS2R4 taste receptor, type 2, member 4 2.57379
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2.57379
C1ORF216 chromosome 1 open reading frame 216 2.57379
KLF11 Kruppel-like factor 11 2.57379
CPNE5 copine V 2.57379
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.57379
SYNJ1 synaptojanin 1 2.57379
POMZP3 POM121 and ZP3 fusion 2.57379
CTU1 cytosolic thiouridylase subunit 1 2.57379
ZNF350 zinc finger protein 350 2.57379
POU2F3 POU class 2 homeobox 3 2.57379
ZBTB22 zinc finger and BTB domain containing 22 2.57379
KIFAP3 kinesin-associated protein 3 2.57379
SYT15 synaptotagmin XV 2.57379
LAMA4 laminin, alpha 4 2.57379
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.57379
TBX10 T-box 10 2.57379
XKR5 XK, Kell blood group complex subunit-related family, member 5 2.57379
ASIC4 acid sensing (proton gated) ion channel family member 4 2.57379
CASKIN1 CASK interacting protein 1 2.57379
SBSN suprabasin 2.57379
CXCL14 chemokine (C-X-C motif) ligand 14 2.57379
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.57379
ZNF578 zinc finger protein 578 2.57379
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.57379
TFEB transcription factor EB 2.57379
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 2.57379
LZTS1 leucine zipper, putative tumor suppressor 1 2.57379
FAM186B family with sequence similarity 186, member B 2.57379
DLC1 DLC1 Rho GTPase activating protein 2.57379
TMEM265 transmembrane protein 265 2.57379
LIME1 Lck interacting transmembrane adaptor 1 2.57379
KDM4D lysine (K)-specific demethylase 4D 2.57379
ZNF549 zinc finger protein 549 2.57379
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.57379
ZNF782 zinc finger protein 782 2.57379
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 2.57379
DCLK2 doublecortin-like kinase 2 2.57379
CXCR4 chemokine (C-X-C motif) receptor 4 2.57379
CRYBB3 crystallin, beta B3 2.57379
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.57379
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.57379
NIPAL3 NIPA-like domain containing 3 2.57379
IL18 interleukin 18 2.57379
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.57379
CCDC183 coiled-coil domain containing 183 2.57379
CRHR2 corticotropin releasing hormone receptor 2 2.57379
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.57379
CCDC22 coiled-coil domain containing 22 2.57379
CBX4 chromobox homolog 4 2.57379
CREG2 cellular repressor of E1A-stimulated genes 2 2.57379
PABPC4L poly(A) binding protein, cytoplasmic 4-like 2.57379
NUTM1 NUT midline carcinoma, family member 1 2.57379
UBQLN4 ubiquilin 4 2.57379
FRS3 fibroblast growth factor receptor substrate 3 2.57379
VMAC vimentin-type intermediate filament associated coiled-coil protein 2.57379
TMEM54 transmembrane protein 54 2.57379
WDR72 WD repeat domain 72 2.57379
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.57379
C3ORF49 chromosome 3 open reading frame 49 2.57379
F2R coagulation factor II (thrombin) receptor 2.57379
FZD8 frizzled class receptor 8 2.57379
MFSD6L major facilitator superfamily domain containing 6-like 2.57379
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.57379
SKAP1 src kinase associated phosphoprotein 1 2.57379
SNTA1 syntrophin, alpha 1 2.57379
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 2.57379
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.57379
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.57379
ZNF2 zinc finger protein 2 2.57379
APOM apolipoprotein M 2.57379
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.57379
RAI1 retinoic acid induced 1 2.57379
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.57379
CER1 cerberus 1, DAN family BMP antagonist 2.57379
UPK1B uroplakin 1B 2.57379
ZNF415 zinc finger protein 415 2.57379
TSPAN15 tetraspanin 15 2.57379
KLHL10 kelch-like family member 10 2.57379
HPCA hippocalcin 2.57379
GPC1 glypican 1 2.57379
PAH phenylalanine hydroxylase 2.57379
CSDC2 cold shock domain containing C2, RNA binding 2.57379
RGS2 regulator of G-protein signaling 2 2.57379
SPATA16 spermatogenesis associated 16 2.57379
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.57379
BCL3 B-cell CLL/lymphoma 3 2.57379
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.57379
SNAP91 synaptosomal-associated protein, 91kDa 2.57379
TEX22 testis expressed 22 2.57379
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 2.57379
CPN1 carboxypeptidase N, polypeptide 1 2.57379
TBKBP1 TBK1 binding protein 1 2.57379
MEIS2 Meis homeobox 2 2.57379
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.57379
FAT2 FAT atypical cadherin 2 2.57379
PLCD1 phospholipase C, delta 1 2.57379
NCOA3 nuclear receptor coactivator 3 2.57379
ART3 ADP-ribosyltransferase 3 2.57379
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 2.57379
CTXN2 cortexin 2 2.57379
LRP2 low density lipoprotein receptor-related protein 2 2.57379
AARD alanine and arginine rich domain containing protein 2.57379
TRAPPC2 trafficking protein particle complex 2 2.57379
CEMIP cell migration inducing protein, hyaluronan binding 2.57379
KLK13 kallikrein-related peptidase 13 2.57379
SLC4A3 solute carrier family 4 (anion exchanger), member 3 2.57379
CRYBA4 crystallin, beta A4 2.57379
TF transferrin 2.57379
IP6K2 inositol hexakisphosphate kinase 2 2.57379
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 2.57379
PRPH2 peripherin 2 (retinal degeneration, slow) 2.57379
RNF208 ring finger protein 208 2.57379
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 2.57379
PLD6 phospholipase D family, member 6 2.57379
PLD1 phospholipase D1, phosphatidylcholine-specific 2.57379
EPHA3 EPH receptor A3 2.57379
SCARF1 scavenger receptor class F, member 1 2.57379
EIF1AD eukaryotic translation initiation factor 1A domain containing 2.57379
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.57379
RUMY1 regulator of UNG2 and MKLN1 interacting yippee protein 1 2.57379
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.57379
RBP5 retinol binding protein 5, cellular 2.57379
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.57379
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.57379
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.57379
DBP D site of albumin promoter (albumin D-box) binding protein 2.57379
OTX1 orthodenticle homeobox 1 2.57379
ICAM5 intercellular adhesion molecule 5, telencephalin 2.57379
NLRP5 NLR family, pyrin domain containing 5 2.57379
WNT5A wingless-type MMTV integration site family, member 5A 2.57379
SETD1B SET domain containing 1B 2.57379
WNT9A wingless-type MMTV integration site family, member 9A 2.57379
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.57379
MMP11 matrix metallopeptidase 11 2.57379
ANXA9 annexin A9 2.57379
LRTM1 leucine-rich repeats and transmembrane domains 1 2.57379
CYSRT1 cysteine-rich tail protein 1 2.57379
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2.57379
CHD1L chromodomain helicase DNA binding protein 1-like 2.57379
ASGR2 asialoglycoprotein receptor 2 2.57379
TMC2 transmembrane channel-like 2 2.57379
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.57379
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.57379
PLXNA3 plexin A3 2.57379
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.57379
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.57379
OIT3 oncoprotein induced transcript 3 2.57379
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.57379
CFAP54 cilia and flagella associated 54 2.57379
ZNF804A zinc finger protein 804A 2.57379
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.57379
ANKRD45 ankyrin repeat domain 45 2.57379
DNAH2 dynein, axonemal, heavy chain 2 2.57379
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.57379
NLRX1 NLR family member X1 2.57379
PADI2 peptidyl arginine deiminase, type II 2.57379
TGM5 transglutaminase 5 2.57379
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.57379
APOL1 apolipoprotein L, 1 2.57379
GPATCH11 G patch domain containing 11 2.57379
GATAD2B GATA zinc finger domain containing 2B 2.57379
TESK1 testis-specific kinase 1 2.57379
VWC2 von Willebrand factor C domain containing 2 2.57379
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 2.57379
SLC51B solute carrier family 51, beta subunit 2.57379
UBOX5 U-box domain containing 5 2.57379
FSTL5 follistatin-like 5 2.57379
C17ORF100 chromosome 17 open reading frame 100 2.57379
PNMT phenylethanolamine N-methyltransferase 2.57379
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.57379
WBP2NL WBP2 N-terminal like 2.57379
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 2.57379
PURA purine-rich element binding protein A 2.57379
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.57379
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.55398
FKBP5 FK506 binding protein 5 2.52144
FNDC10 fibronectin type III domain containing 10 2.47253
BEX1 brain expressed, X-linked 1 2.47174
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.46387
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 2.45152
TMEM114 transmembrane protein 114 2.40484
REC8 REC8 meiotic recombination protein 2.40484
CCNJL cyclin J-like 2.40426
PDE5A phosphodiesterase 5A, cGMP-specific 2.37449
MARCKSL1 MARCKS-like 1 2.37355
CYB5R3 cytochrome b5 reductase 3 2.36644
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.3351
PYCR1 pyrroline-5-carboxylate reductase 1 2.33138
EME1 essential meiotic structure-specific endonuclease 1 2.32317
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.32112
FYN FYN proto-oncogene, Src family tyrosine kinase 2.31248
TMEM108 transmembrane protein 108 2.30479
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.30382
UNC119 unc-119 homolog (C. elegans) 2.26553
GAB1 GRB2-associated binding protein 1 2.26358
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.23373
NTS neurotensin 2.23272
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 2.22752
GMDS GDP-mannose 4,6-dehydratase 2.22565
CSNK2A2 casein kinase 2, alpha prime polypeptide 2.19753
XYLT1 xylosyltransferase I 2.19753
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.18676
ACSS3 acyl-CoA synthetase short-chain family member 3 2.18374
ZFP41 ZFP41 zinc finger protein 2.16908
KIAA2013 KIAA2013 2.16908
CA14 carbonic anhydrase XIV 2.16181
ZNF250 zinc finger protein 250 2.16134
NOTCH2NLC notch 2 N-terminal like C 2.16134
NPM2 nucleophosmin/nucleoplasmin 2 2.16134
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.16134
ZNF79 zinc finger protein 79 2.16134
HDAC10 histone deacetylase 10 2.16134
ZNF419 zinc finger protein 419 2.16134
MVK mevalonate kinase 2.16134
FAM151B family with sequence similarity 151, member B 2.16134
NR2E3 nuclear receptor subfamily 2, group E, member 3 2.16134
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.16134
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.16134
UBE2L5 ubiquitin conjugating enzyme E2 L5 2.16134
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.16134
EPS8L1 EPS8-like 1 2.16134
ZFP36 ZFP36 ring finger protein 2.16134
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 2.16134
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.16134
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.16134
FAAP20 FA core complex associated protein 20 2.15452
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 2.14469
FBXO3 F-box protein 3 2.13815
LPCAT2 lysophosphatidylcholine acyltransferase 2 2.13815
ZNF182 zinc finger protein 182 2.12183
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2.12183
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.12183
GOLGA8A golgin A8 family, member A 2.12183
GPM6A glycoprotein M6A 2.12183
CDX4 caudal type homeobox 4 2.12183
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.12183
ZNF783 zinc finger family member 783 2.12183
NEFL neurofilament, light polypeptide 2.12183
ZNF154 zinc finger protein 154 2.12183
PLPPR3 phospholipid phosphatase related 3 2.12183
NPR2 natriuretic peptide receptor 2 2.12183
LHFPL1 lipoma HMGIC fusion partner-like 1 2.12183
FGF8 fibroblast growth factor 8 (androgen-induced) 2.12183
C12ORF57 chromosome 12 open reading frame 57 2.12183
CEP89 centrosomal protein 89kDa 2.12183
PDE4A phosphodiesterase 4A, cAMP-specific 2.12183
CD109 CD109 molecule 2.12183
PLEKHA5 pleckstrin homology domain containing, family A member 5 2.12183
DGKQ diacylglycerol kinase, theta 110kDa 2.12183
FAM13C family with sequence similarity 13, member C 2.12183
CFAP69 cilia and flagella associated protein 69 2.12183
RARA retinoic acid receptor, alpha 2.12183
MCFD2 multiple coagulation factor deficiency 2 2.10322
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.07463
NPTN neuroplastin 2.07384
RNF114 ring finger protein 114 2.07384
MRPS6 mitochondrial ribosomal protein S6 2.07384
USP15 ubiquitin specific peptidase 15 2.07163
GSK3B glycogen synthase kinase 3 beta 2.0502
ANKRD13C ankyrin repeat domain 13C 2.04774
PDE3A phosphodiesterase 3A, cGMP-inhibited 2.005
PARL presenilin associated, rhomboid-like 2.00311

decreased expression

Symbol Name Standardized Value
EFNB2 ephrin-B2 -2.69346
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -2.69346
TTLL12 tubulin tyrosine ligase-like family member 12 -2.69346
MYO1C myosin IC -2.69346
ANO2 anoctamin 2, calcium activated chloride channel -2.69346
HPDL 4-hydroxyphenylpyruvate dioxygenase-like -2.69346
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -2.69346
GSK3A glycogen synthase kinase 3 alpha -2.69346
TMEM218 transmembrane protein 218 -2.69346
CIBAR1 CBY1 interacting BAR domain containing 1 -2.69346
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 -2.57379
ZFYVE1 zinc finger, FYVE domain containing 1 -2.57379
TRIM36 tripartite motif containing 36 -2.57379
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.57379
CEP95 centrosomal protein 95kDa -2.57379
ZNF667 zinc finger protein 667 -2.57379
GRIK3 glutamate receptor, ionotropic, kainate 3 -2.57379
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase -2.57379
ZNF473 zinc finger protein 473 -2.57379
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -2.57379
CELA2B chymotrypsin-like elastase family, member 2B -2.57379
HYI hydroxypyruvate isomerase (putative) -2.57379
ZNF584 zinc finger protein 584 -2.57379
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.57379
MUTYH mutY homolog -2.57379
MPST mercaptopyruvate sulfurtransferase -2.57379
TMEM150C transmembrane protein 150C -2.57379
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.57379
ZNF669 zinc finger protein 669 -2.57379
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -2.57379
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -2.57379
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.57379
DIO2 deiodinase, iodothyronine, type II -2.57379
ZFYVE27 zinc finger, FYVE domain containing 27 -2.57379
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -2.57379
SUSD4 sushi domain containing 4 -2.57379
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -2.57379
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.57379
GLIS2 GLIS family zinc finger 2 -2.57379
OLFM2 olfactomedin 2 -2.57379
DRAM1 DNA-damage regulated autophagy modulator 1 -2.57379
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -2.57379
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -2.57379
SESN1 sestrin 1 -2.57379
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -2.57379
FDXR ferredoxin reductase -2.57379
OLFML2A olfactomedin-like 2A -2.57379
SSH3 slingshot protein phosphatase 3 -2.57379
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -2.57379
ZNF45 zinc finger protein 45 -2.57379
MRRF mitochondrial ribosome recycling factor -2.57379
MOGAT1 monoacylglycerol O-acyltransferase 1 -2.57379
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -2.57379
ZNF223 zinc finger protein 223 -2.57379
RDM1 RAD52 motif containing 1 -2.57379
FAM219B family with sequence similarity 219, member B -2.57379
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -2.57379
RNF170 ring finger protein 170 -2.57379
RIOX2 ribosomal oxygenase 2 -2.57379
CCDC181 coiled-coil domain containing 181 -2.57379
STAC2 SH3 and cysteine rich domain 2 -2.57379
COASY CoA synthase -2.57379
TPRG1L tumor protein p63 regulated 1-like -2.57379
FBXO41 F-box protein 41 -2.57379
FAM241A family with sequence similarity 241 member A -2.57379
POGK pogo transposable element with KRAB domain -2.57379
TEP1 telomerase-associated protein 1 -2.57379
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.57379
ERCC6 excision repair cross-complementation group 6 -2.57379
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -2.57379
UBALD1 UBA-like domain containing 1 -2.57379
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -2.57379
VGLL3 vestigial-like family member 3 -2.57379
RNASET2 ribonuclease T2 -2.57379
STYX serine/threonine/tyrosine interacting protein -2.57379
SLC33A2 solute carrier family 33 member 2 -2.57379
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -2.57379
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.57379
MTMR7 myotubularin related protein 7 -2.57379
GLA galactosidase, alpha -2.57379
CPEB1 cytoplasmic polyadenylation element binding protein 1 -2.57379
ING4 inhibitor of growth family, member 4 -2.57379
YAF2 YY1 associated factor 2 -2.57379
DOC2A double C2-like domains, alpha -2.57379
RGS20 regulator of G-protein signaling 20 -2.57379
RIPOR3 RIPOR family member 3 -2.57379
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.57379
WDR47 WD repeat domain 47 -2.57379
LARGE1 LARGE xylosyl- and glucuronyltransferase 1 -2.57379
JAK3 Janus kinase 3 -2.57379
ZNF785 zinc finger protein 785 -2.57379
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.56069
SLAIN2 SLAIN motif family, member 2 -2.55181
TRIM26 tripartite motif containing 26 -2.55155
MECR mitochondrial trans-2-enoyl-CoA reductase -2.55155
PEMT phosphatidylethanolamine N-methyltransferase -2.55155
PPP1R12A protein phosphatase 1, regulatory subunit 12A -2.55155
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.55155
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -2.55155
PDLIM1 PDZ and LIM domain 1 -2.54536
PCLAF PCNA clamp associated factor -2.53777
LAS1L LAS1-like (S. cerevisiae) -2.49562
PRDM5 PR domain containing 5 -2.48403
ZYG11B zyg-11 family member B, cell cycle regulator -2.47853
ZDHHC18 zinc finger, DHHC-type containing 18 -2.45152
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.45152
WIPF2 WAS/WASL interacting protein family, member 2 -2.45152
HEATR4 HEAT repeat containing 4 -2.45152
FOXA3 forkhead box A3 -2.45152
SP110 SP110 nuclear body protein -2.45152
USP43 ubiquitin specific peptidase 43 -2.45152
PLXNB2 plexin B2 -2.45152
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 -2.45152
SMTN smoothelin -2.45152
TYSND1 trypsin domain containing 1 -2.45152
FAM227A family with sequence similarity 227, member A -2.45152
GPC5 glypican 5 -2.45152
MSL3 male-specific lethal 3 homolog (Drosophila) -2.45152
CSK c-src tyrosine kinase -2.45152
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) -2.45152
CENPT centromere protein T -2.45152
EIF4A3 eukaryotic translation initiation factor 4A3 -2.41253
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -2.40635
AMBRA1 autophagy/beclin-1 regulator 1 -2.38893
ECPAS Ecm29 proteasome adaptor and scaffold -2.35081
EIF4E3 eukaryotic translation initiation factor 4E family member 3 -2.31569
EID2 EP300 interacting inhibitor of differentiation 2 -2.31569
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -2.3079
EFTUD2 elongation factor Tu GTP binding domain containing 2 -2.27823
TOX3 TOX high mobility group box family member 3 -2.25962
PYM1 PYM homolog 1, exon junction complex associated factor -2.23452
ZNF41 zinc finger protein 41 -2.23431
CYB5R2 cytochrome b5 reductase 2 -2.23431
MAMDC2 MAM domain containing 2 -2.23431
FNBP1L formin binding protein 1-like -2.23351
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -2.23351
MAP2K1 mitogen-activated protein kinase kinase 1 -2.20429
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -2.20429
PRR5L proline rich 5 like -2.20429
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.20411
SART3 squamous cell carcinoma antigen recognized by T cells 3 -2.18911
DAZL deleted in azoospermia-like -2.17372
UNC50 unc-50 homolog (C. elegans) -2.17372
RNH1 ribonuclease/angiogenin inhibitor 1 -2.16134
RUFY2 RUN and FYVE domain containing 2 -2.15919
ZMYND8 zinc finger, MYND-type containing 8 -2.12183
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -2.12032
FKBP15 FK506 binding protein 15, 133kDa -2.07384
ENTREP2 endosomal transmembrane epsin interactor 2 -2.07384
ARHGAP18 Rho GTPase activating protein 18 -2.07384
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -2.07384
CEP131 centrosomal protein 131kDa -2.07384
TSKU tsukushi, small leucine rich proteoglycan -2.07384
CFAP96 cilia and flagella associated protein 96 -2.07384
CALCOCO1 calcium binding and coiled-coil domain 1 -2.07384
CLVS1 clavesin 1 -2.07384
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -2.07384
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.07384
COMMD8 COMM domain containing 8 -2.07384
RNF122 ring finger protein 122 -2.07384
GIPC2 GIPC PDZ domain containing family, member 2 -2.07384
ZBTB18 zinc finger and BTB domain containing 18 -2.07384
WDR17 WD repeat domain 17 -2.07384
PLA2G3 phospholipase A2, group III -2.07384
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 -2.07384
KLC4 kinesin light chain 4 -2.07384
CR1L complement component (3b/4b) receptor 1-like -2.07384
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 -2.07384
RPUSD1 RNA pseudouridylate synthase domain containing 1 -2.07384
USP21 ubiquitin specific peptidase 21 -2.07384
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 -2.07384
SMG8 SMG8 nonsense mediated mRNA decay factor -2.07384
HOMEZ homeobox and leucine zipper encoding -2.07384
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -2.07384
POLG polymerase (DNA directed), gamma -2.07384
IER5 immediate early response 5 -2.07384
LEMD1 LEM domain containing 1 -2.07384
NF2 neurofibromin 2 (merlin) -2.07384
AFP alpha-fetoprotein -2.07384
SMIM10L2B small integral membrane protein 10 like 2B -2.07384
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -2.07384
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -2.07384
INTS8 integrator complex subunit 8 -2.07384
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -2.07384
ZNF500 zinc finger protein 500 -2.07384
SCPEP1 serine carboxypeptidase 1 -2.07384
CDK5 cyclin-dependent kinase 5 -2.07384
EFHC2 EF-hand domain (C-terminal) containing 2 -2.07384
CCDC157 coiled-coil domain containing 157 -2.07384
CLIP3 CAP-GLY domain containing linker protein 3 -2.07384
FNTB farnesyltransferase, CAAX box, beta -2.07384
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -2.07384
TRIM61 tripartite motif containing 61 -2.07384
NBPF3 neuroblastoma breakpoint family, member 3 -2.07384
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.07384
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.07384
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.07384
ANKRD13B ankyrin repeat domain 13B -2.07384
RANBP2 RAN binding protein 2 -2.07194
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.06117
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -2.05926
APELA apelin receptor early endogenous ligand -2.05863
MAGT1 magnesium transporter 1 -2.05607
ARHGAP32 Rho GTPase activating protein 32 -2.04435
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -2.03935
FHIP1A FHF complex subunit HOOK interacting protein 1A -2.03585
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -2.03492
DENND1A DENN/MADD domain containing 1A -2.03116
WDR3 WD repeat domain 3 -2.03088
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.02285
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -2.02283
STOML2 stomatin (EPB72)-like 2 -2.00964