CDC6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cell division cycle 6|The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 990)
External Link https://ncbi.nlm.nih.gov/gene/990
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Genes

499 genes differentially expressed following the CDC6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BMP4 bone morphogenetic protein 4 0.0151248
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0150757
TGFBI transforming growth factor, beta-induced, 68kDa 0.0129706
LTF lactotransferrin 0.0122967
LGALS1 lectin, galactoside-binding, soluble, 1 0.0109746
CXCL9 chemokine (C-X-C motif) ligand 9 0.0109159
PCP4 Purkinje cell protein 4 0.0108698
GPX3 glutathione peroxidase 3 0.010672
RHOBTB3 Rho-related BTB domain containing 3 0.00991785
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00965615
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00948342
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00947086
TGFB1 transforming growth factor, beta 1 0.00935557
RNF167 ring finger protein 167 0.00921734
CNN3 calponin 3, acidic 0.00914677
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00911804
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00896008
CFB complement factor B 0.00878594
SSBP2 single-stranded DNA binding protein 2 0.00875742
MGP matrix Gla protein 0.00866427
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00856898
PFN2 profilin 2 0.00848591
RAPSN receptor-associated protein of the synapse 0.00848232
FABP4 fatty acid binding protein 4, adipocyte 0.00839046
G6PD glucose-6-phosphate dehydrogenase 0.00838221
NPY neuropeptide Y 0.00836199
NIBAN1 niban apoptosis regulator 1 0.00833416
ACSL3 acyl-CoA synthetase long-chain family member 3 0.00822852
CHI3L2 chitinase 3-like 2 0.00794192
LYZ lysozyme 0.00791149
PLK2 polo-like kinase 2 0.00790078
FGL2 fibrinogen-like 2 0.00779067
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00777076
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00775569
PROM1 prominin 1 0.00757499
CD36 CD36 molecule (thrombospondin receptor) 0.00757282
CTSH cathepsin H 0.00749536
FN1 fibronectin 1 0.00746185
NRGN neurogranin (protein kinase C substrate, RC3) 0.00745341
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00743488
OLFML2A olfactomedin-like 2A 0.00741484
ACAT2 acetyl-CoA acetyltransferase 2 0.00737997
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00734928
IDO1 indoleamine 2,3-dioxygenase 1 0.00732415
SDC2 syndecan 2 0.00732311
TRIB2 tribbles pseudokinase 2 0.00732058
SOX9 SRY (sex determining region Y)-box 9 0.00731952
PHACTR2 phosphatase and actin regulator 2 0.00728798
SPTSSA serine palmitoyltransferase, small subunit A 0.00719702
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00705748
TM4SF1 transmembrane 4 L six family member 1 0.00698198
RAD23B RAD23 homolog B (S. cerevisiae) 0.00697941
FASN fatty acid synthase 0.00687865
H1-2 H1.2 linker histone, cluster member 0.00682038
RTN1 reticulon 1 0.00676906
KAZN kazrin, periplakin interacting protein 0.00676718
CXCL10 chemokine (C-X-C motif) ligand 10 0.00664943
PTK2 protein tyrosine kinase 2 0.00662328
METTL7A methyltransferase like 7A 0.00655986
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00654885
DYNLL1 dynein, light chain, LC8-type 1 0.00653502
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00650894
PTK2B protein tyrosine kinase 2 beta 0.00649275
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00645581
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0064434
LPAR6 lysophosphatidic acid receptor 6 0.00640825
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00637286
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00636143
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00634344
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00633547
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.00630923
CPB1 carboxypeptidase B1 (tissue) 0.00630116
SPRED2 sprouty-related, EVH1 domain containing 2 0.00629257
TNC tenascin C 0.00628539
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00628149
CXCL14 chemokine (C-X-C motif) ligand 14 0.00625796
TSPAN7 tetraspanin 7 0.00619084
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00610597
TSPO translocator protein (18kDa) 0.00609319
AHR aryl hydrocarbon receptor 0.00607068
CRABP2 cellular retinoic acid binding protein 2 0.00604546
PXDC1 PX domain containing 1 0.00601095
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00599465
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00597727
NPM3 nucleophosmin/nucleoplasmin 3 0.00597168
ZIC1 Zic family member 1 0.00597083
JCHAIN joining chain of multimeric IgA and IgM 0.00594978
KANK1 KN motif and ankyrin repeat domains 1 0.00591425
CPE carboxypeptidase E 0.00590461
GCLC glutamate-cysteine ligase, catalytic subunit 0.00589217
CST3 cystatin C 0.00589001
DNASE1L3 deoxyribonuclease I-like 3 0.0058621
MN1 meningioma (disrupted in balanced translocation) 1 0.00584948
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00583149
G0S2 G0/G1 switch 2 0.00581207
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00579486
CLIC4 chloride intracellular channel 4 0.00577945
PMP22 peripheral myelin protein 22 0.00576027
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00574573
MSMO1 methylsterol monooxygenase 1 0.00572361
EMP3 epithelial membrane protein 3 0.00570985
NIPSNAP2 nipsnap homolog 2 0.00569269
NDFIP1 Nedd4 family interacting protein 1 0.00568432
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00567555
CUX2 cut-like homeobox 2 0.00563871
NMU neuromedin U 0.00562835
HSPB1 heat shock 27kDa protein 1 0.00559205
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.0055826
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00558146
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00557308
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00555244
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00554116
NMB neuromedin B 0.00551831
PLBD1 phospholipase B domain containing 1 0.00550256
ENO2 enolase 2 (gamma, neuronal) 0.00548462
RHOB ras homolog family member B 0.00546547
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00545295
NRN1 neuritin 1 0.00543578
ADK adenosine kinase 0.00542499
EFNB2 ephrin-B2 0.00538841
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.00538336
CCND2 cyclin D2 0.00535589
RNASE6 ribonuclease, RNase A family, k6 0.00533109
DGKZ diacylglycerol kinase, zeta 0.00533044
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00531962
PKM pyruvate kinase, muscle 0.0053164
CCDC47 coiled-coil domain containing 47 0.00531337
GJA1 gap junction protein, alpha 1, 43kDa 0.00530691
SC5D sterol-C5-desaturase 0.00524852
DBF4 DBF4 zinc finger 0.00523834
ELOVL5 ELOVL fatty acid elongase 5 0.00523542
TMSB15A thymosin beta 15a 0.00521305
PEA15 phosphoprotein enriched in astrocytes 15 0.00521161
AMD1 adenosylmethionine decarboxylase 1 0.0051898
CHP1 calcineurin-like EF-hand protein 1 0.00518908
AUTS2 autism susceptibility candidate 2 0.00518848
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00517425
YME1L1 YME1-like 1 ATPase 0.00517364
ATP13A3 ATPase type 13A3 0.00517109
CCDC86 coiled-coil domain containing 86 0.00516941
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00515965
C1ORF54 chromosome 1 open reading frame 54 0.00515106
MAP2K1 mitogen-activated protein kinase kinase 1 0.00513977
KLF9 Kruppel-like factor 9 0.00513861
SORBS2 sorbin and SH3 domain containing 2 0.00511537
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.0051148
MAOA monoamine oxidase A 0.00510557
RPA3 replication protein A3, 14kDa 0.00510097
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00509708
FHL1 four and a half LIM domains 1 0.00509089
PLEK pleckstrin 0.0050902
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00508705
CD300A CD300a molecule 0.00508656
GLUL glutamate-ammonia ligase 0.00508501
METTL5 methyltransferase like 5 0.00507815
P3H2 prolyl 3-hydroxylase 2 0.00507623
LDB2 LIM domain binding 2 0.00506497
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00506075
BEX4 brain expressed, X-linked 4 0.00503566
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00503102
CXCL13 chemokine (C-X-C motif) ligand 13 0.00502477
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00501651
CRLF1 cytokine receptor-like factor 1 0.00501175
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00500766
TSPAN13 tetraspanin 13 0.00499739
DHCR7 7-dehydrocholesterol reductase 0.00498664
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0049857
CCNC cyclin C 0.00498183
CPVL carboxypeptidase, vitellogenic-like 0.00497453
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00496516
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00494264
APOC1 apolipoprotein C-I 0.00493969
HTRA1 HtrA serine peptidase 1 0.00492184
NAMPT nicotinamide phosphoribosyltransferase 0.00491516
RIDA reactive intermediate imine deaminase A homolog 0.00488197
A2M alpha-2-macroglobulin 0.00487822
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.00486867
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00485536
LRRC17 leucine rich repeat containing 17 0.00484582
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.0048144
KIF20A kinesin family member 20A 0.00480969
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00479676
PEG10 paternally expressed 10 0.00479419
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00478508
CD302 CD302 molecule 0.0047778
CP ceruloplasmin (ferroxidase) 0.00476567
NOTCH1 notch 1 0.00475138
KLHDC3 kelch domain containing 3 0.00474935
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00474758
ENG endoglin 0.0047464
NNAT neuronatin 0.00473863
RAP1A RAP1A, member of RAS oncogene family 0.00472785
BIN2 bridging integrator 2 0.00470218
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.00469223
SNX10 sorting nexin 10 0.00469043
FAM172A family with sequence similarity 172, member A 0.00468974
CEP70 centrosomal protein 70kDa 0.00468497
HLA-C major histocompatibility complex, class I, C 0.00468119
SQLE squalene epoxidase 0.00467281
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.00466676
ANKMY2 ankyrin repeat and MYND domain containing 2 0.00466432
CLEC10A C-type lectin domain family 10, member A 0.00464961
ADAM9 ADAM metallopeptidase domain 9 0.00464877
HOXB2 homeobox B2 0.0046312
ZNF395 zinc finger protein 395 0.00462982
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00462819
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.00462663
HIRA histone cell cycle regulator 0.0046234
EYA1 EYA transcriptional coactivator and phosphatase 1 0.00456746
CLEC2B C-type lectin domain family 2, member B 0.00455701
DACH1 dachshund family transcription factor 1 0.00455112
ING3 inhibitor of growth family, member 3 0.00454771
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00454334
EXPH5 exophilin 5 0.00453979
PDE4A phosphodiesterase 4A, cAMP-specific 0.0045292
FZD4 frizzled class receptor 4 0.00452415
APMAP adipocyte plasma membrane associated protein 0.00452305
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00451379
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.00451204
PDE8B phosphodiesterase 8B 0.00450429
FAM234B family with sequence similarity 234 member B 0.00450397
OLFM4 olfactomedin 4 0.00449691
DCK deoxycytidine kinase 0.00448763
PGF placental growth factor 0.00446416
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.00446114
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00445723
PTPA protein phosphatase 2 phosphatase activator 0.00444846
EFHD2 EF-hand domain family, member D2 0.00444602
CBX6 chromobox homolog 6 0.0044422
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.00443686
ZEB1 zinc finger E-box binding homeobox 1 0.00443415
TAC1 tachykinin, precursor 1 0.00442309
NPTN neuroplastin 0.0044152
IGSF6 immunoglobulin superfamily, member 6 0.00439947
SPARCL1 SPARC-like 1 (hevin) 0.00439822
PGC progastricsin (pepsinogen C) 0.00439231
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00438775
CA11 carbonic anhydrase XI 0.0043856
TGM2 transglutaminase 2 0.00438423
H1-0 H1.0 linker histone 0.00437015
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.00436172
FRY furry homolog (Drosophila) 0.00435878
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00435458
UBP1 upstream binding protein 1 (LBP-1a) 0.00435136
PLPP3 phospholipid phosphatase 3 0.0043455
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.00433533
ANPEP alanyl (membrane) aminopeptidase 0.00432265
STAG2 stromal antigen 2 0.00432105
H2AX H2A.X variant histone 0.00430472
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00429495

decreased expression

Symbol Name Standardized Value
WASHC4 WASH complex subunit 4 -0.0168759
HOXC6 homeobox C6 -0.0119763
BHLHE41 basic helix-loop-helix family, member e41 -0.0118591
SCGB1D2 secretoglobin, family 1D, member 2 -0.0113585
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0113047
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0111656
IFI27 interferon, alpha-inducible protein 27 -0.010659
SCGB2A2 secretoglobin, family 2A, member 2 -0.0101549
MAGEA3 melanoma antigen family A3 -0.0100027
SCGB2A1 secretoglobin, family 2A, member 1 -0.00992533
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00955518
GUCY2C guanylate cyclase 2C -0.00952368
TFF1 trefoil factor 1 -0.00923998
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00919855
HOXB7 homeobox B7 -0.00901199
GATA6 GATA binding protein 6 -0.00882689
TSPAN8 tetraspanin 8 -0.00881988
HAL histidine ammonia-lyase -0.0087949
TFF3 trefoil factor 3 (intestinal) -0.00879475
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00866689
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00853804
S100A7 S100 calcium binding protein A7 -0.00845992
EGR1 early growth response 1 -0.00815446
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00811126
ISG20 interferon stimulated exonuclease gene 20kDa -0.00804299
INSR insulin receptor -0.00798996
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00787109
IFI6 interferon, alpha-inducible protein 6 -0.00783558
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00776682
DEFB1 defensin, beta 1 -0.00772101
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00771859
MYRF myelin regulatory factor -0.00770717
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00763992
EGR3 early growth response 3 -0.00756787
SPRR2B small proline-rich protein 2B -0.00753859
TM4SF4 transmembrane 4 L six family member 4 -0.00748362
CRIP1 cysteine-rich protein 1 (intestinal) -0.00745161
KRT81 keratin 81, type II -0.00744865
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00744021
MME membrane metallo-endopeptidase -0.00740541
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00734729
MAGEA12 melanoma antigen family A12 -0.00731014
MFAP3L microfibrillar-associated protein 3-like -0.00730698
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00729865
GAS1 growth arrest-specific 1 -0.00721906
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00709847
KLF6 Kruppel-like factor 6 -0.00708869
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00706887
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00696894
RHOF ras homolog family member F (in filopodia) -0.00694881
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.00692329
SLPI secretory leukocyte peptidase inhibitor -0.00687012
MAGEA1 melanoma antigen family A1 -0.00684035
COL14A1 collagen, type XIV, alpha 1 -0.00680732
KLK10 kallikrein-related peptidase 10 -0.00680522
HOXB6 homeobox B6 -0.00662233
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00653613
ISG15 ISG15 ubiquitin-like modifier -0.00652924
HMOX1 heme oxygenase 1 -0.00652715
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00650972
PI3 peptidase inhibitor 3, skin-derived -0.00646157
MAMLD1 mastermind-like domain containing 1 -0.00645747
FGFR1 fibroblast growth factor receptor 1 -0.00642915
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00640863
CLEC11A C-type lectin domain family 11, member A -0.00638201
CCNA2 cyclin A2 -0.0063451
POPDC3 popeye domain containing 3 -0.00631414
LY6D lymphocyte antigen 6 complex, locus D -0.00629976
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00625758
IER2 immediate early response 2 -0.0062566
COL15A1 collagen, type XV, alpha 1 -0.0062526
VNN1 vanin 1 -0.00622253
EGR2 early growth response 2 -0.00620103
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00619777
COL10A1 collagen, type X, alpha 1 -0.00617258
NVL nuclear VCP-like -0.00616244
RBBP4 retinoblastoma binding protein 4 -0.00613797
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00609077
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00604688
PLCB4 phospholipase C, beta 4 -0.00604494
MFAP5 microfibrillar associated protein 5 -0.00602845
LAMA2 laminin, alpha 2 -0.00599929
DSP desmoplakin -0.00598478
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00594154
SYT1 synaptotagmin I -0.00592011
GREB1 growth regulation by estrogen in breast cancer 1 -0.00591325
RNASET2 ribonuclease T2 -0.00590092
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00587765
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00587623
MX2 MX dynamin-like GTPase 2 -0.00587367
DCN decorin -0.00585736
LDB3 LIM domain binding 3 -0.00585457
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00585342
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00583981
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00583738
RPS26 ribosomal protein S26 -0.00581663
CRCT1 cysteine-rich C-terminal 1 -0.0057879
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00578736
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00578642
ARL14 ADP-ribosylation factor-like 14 -0.00578362
HEPH hephaestin -0.00578089
ATP10B ATPase, class V, type 10B -0.00576486
CD81 CD81 molecule -0.00575605
PDZK1IP1 PDZK1 interacting protein 1 -0.00572881
OSR2 odd-skipped related transciption factor 2 -0.00571696
ALDOB aldolase B, fructose-bisphosphate -0.00571591
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00569976
VPREB1 pre-B lymphocyte 1 -0.00568504
THBS2 thrombospondin 2 -0.0056779
COQ8A coenzyme Q8A -0.00565081
MX1 MX dynamin-like GTPase 1 -0.00563441
ZDHHC11 zinc finger, DHHC-type containing 11 -0.0056157
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0056122
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00555973
C7 complement component 7 -0.00550604
TST thiosulfate sulfurtransferase (rhodanese) -0.005497
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00546066
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00545518
PTK6 protein tyrosine kinase 6 -0.00544978
WISP1 WNT1 inducible signaling pathway protein 1 -0.00544831
SSPN sarcospan -0.00539037
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.00538507
SPRR1A small proline-rich protein 1A -0.00538439
FBLN5 fibulin 5 -0.0053696
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.00534597
FA2H fatty acid 2-hydroxylase -0.00534442
ANK2 ankyrin 2, neuronal -0.00533498
CHGB chromogranin B -0.00532332
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00532234
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00527356
CFD complement factor D (adipsin) -0.00525212
SLC22A18 solute carrier family 22, member 18 -0.00523081
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00522766
KRT14 keratin 14, type I -0.00519866
SPRR1B small proline-rich protein 1B -0.00519075
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00517958
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00517139
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.00515821
BRCA1 breast cancer 1, early onset -0.00512913
ASS1 argininosuccinate synthase 1 -0.00511376
DSG1 desmoglein 1 -0.00510852
TTC39A tetratricopeptide repeat domain 39A -0.00510797
THBS1 thrombospondin 1 -0.00510063
RHCG Rh family, C glycoprotein -0.00508807
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -0.00508742
CD79B CD79b molecule, immunoglobulin-associated beta -0.00508407
IL36G interleukin 36, gamma -0.00507875
TRIM36 tripartite motif containing 36 -0.00507855
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00503325
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00503034
KRT1 keratin 1, type II -0.00502849
TMEM176B transmembrane protein 176B -0.00502494
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00501826
NAV3 neuron navigator 3 -0.00501364
CLDN10 claudin 10 -0.00501017
BTG1 B-cell translocation gene 1, anti-proliferative -0.00500201
LINC00623 long intergenic non-protein coding RNA 623 -0.00499209
MMP19 matrix metallopeptidase 19 -0.00496153
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.0049499
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.00493162
KLK13 kallikrein-related peptidase 13 -0.00492594
LEFTY1 left-right determination factor 1 -0.00490299
CALML5 calmodulin-like 5 -0.00489742
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00489315
OPTN optineurin -0.0048838
TRIM38 tripartite motif containing 38 -0.0048685
AATF apoptosis antagonizing transcription factor -0.00486584
TRIM16 tripartite motif containing 16 -0.0048343
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00482214
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00482155
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00481916
FBXO11 F-box protein 11 -0.00481459
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -0.00480565
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00478943
DSC1 desmocollin 1 -0.0047757
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00475587
SCEL sciellin -0.00473004
HEATR1 HEAT repeat containing 1 -0.00472064
CYB5R2 cytochrome b5 reductase 2 -0.00471501
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.00470474
LRRN3 leucine rich repeat neuronal 3 -0.00469875
ALPP alkaline phosphatase, placental -0.00467643
AMDHD2 amidohydrolase domain containing 2 -0.00466795
MLXIP MLX interacting protein -0.00466001
SOX4 SRY (sex determining region Y)-box 4 -0.00465855
WDTC1 WD and tetratricopeptide repeats 1 -0.00463228
MEG3 maternally expressed 3 (non-protein coding) -0.00462001
TYRP1 tyrosinase-related protein 1 -0.00460975
PAWR PRKC, apoptosis, WT1, regulator -0.00460592
NPTX2 neuronal pentraxin II -0.00459799
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.0045974
TM4SF20 transmembrane 4 L six family member 20 -0.0045935
WT1 Wilms tumor 1 -0.00458783
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.00458048
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00457666
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00457666
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00457448
DSG3 desmoglein 3 -0.0045701
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00456765
BIRC3 baculoviral IAP repeat containing 3 -0.00455732
XPO7 exportin 7 -0.00455027
LMCD1 LIM and cysteine-rich domains 1 -0.00454504
PRKD1 protein kinase D1 -0.00454245
JADE2 jade family PHD finger 2 -0.00453961
ANKRD11 ankyrin repeat domain 11 -0.00453838
UPP1 uridine phosphorylase 1 -0.00453635
EPHX3 epoxide hydrolase 3 -0.00453252
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00453144
ZFP36 ZFP36 ring finger protein -0.00452389
PEBP1 phosphatidylethanolamine binding protein 1 -0.0045156
SCCPDH saccharopine dehydrogenase (putative) -0.00451485
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -0.00451261
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00451012
CNTN1 contactin 1 -0.00449079
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00448707
PLPP2 phospholipid phosphatase 2 -0.00447932
UGT8 UDP glycosyltransferase 8 -0.00447821
FOXL2 forkhead box L2 -0.00447656
PRSS21 protease, serine, 21 (testisin) -0.00445883
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00445201
PCDH9 protocadherin 9 -0.00444652
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00444408
MUC4 mucin 4, cell surface associated -0.00443335
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00442852
PSAT1 phosphoserine aminotransferase 1 -0.00442371
TKTL1 transketolase-like 1 -0.00441925
STATH statherin -0.00441915
FMO1 flavin containing monooxygenase 1 -0.00441698
BPGM 2,3-bisphosphoglycerate mutase -0.00441201
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00440292
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00438985
OAZ1 ornithine decarboxylase antizyme 1 -0.00438904
OLFML3 olfactomedin-like 3 -0.00438574
ELANE elastase, neutrophil expressed -0.00438503
PUF60 poly-U binding splicing factor 60KDa -0.00437952
TP53I3 tumor protein p53 inducible protein 3 -0.0043633
LAMC2 laminin, gamma 2 -0.00435249
FERMT1 fermitin family member 1 -0.00434093
MISP mitotic spindle positioning -0.00432351
PODXL podocalyxin-like -0.00431368
SAMD9 sterile alpha motif domain containing 9 -0.00431303
EPPK1 epiplakin 1 -0.00430814
AIM2 absent in melanoma 2 -0.00430339
BCAS1 breast carcinoma amplified sequence 1 -0.00429861
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.0042948
ANXA9 annexin A9 -0.00429059
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00428777
RRAD Ras-related associated with diabetes -0.00427798
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00427719