CDC7 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cell division cycle 7|This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 8317)
External Link http://www.ncbi.nlm.nih.gov/gene/8317
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Genes

43 interacting proteins for CDC7 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHAF1A chromatin assembly factor 1, subunit A (p150)
CLSPN claspin
DBF4 DBF4 zinc finger
DBF4B DBF4 zinc finger B
DIAPH1 diaphanous-related formin 1
E2F1 E2F transcription factor 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRHPR glyoxylate reductase/hydroxypyruvate reductase
ICK intestinal cell (MAK-like) kinase
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MCMBP minichromosome maintenance complex binding protein
NRF1 nuclear respiratory factor 1
ORC1 origin recognition complex, subunit 1
ORC2 origin recognition complex, subunit 2
ORC4 origin recognition complex, subunit 4
ORC5 origin recognition complex, subunit 5
ORC6 origin recognition complex, subunit 6
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PSIP1 PC4 and SFRS1 interacting protein 1
RAD18 RAD18 E3 ubiquitin protein ligase
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TOB1 transducer of ERBB2, 1
UBC ubiquitin C