CDC73 Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description cell division cycle 73|This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009] (NCBI Entrez Gene Database, 79577)
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5 interacting proteins for CDC73 from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 1.01444
CTR9 CTR9, Paf1/RNA polymerase II complex component 0.9262
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.656812
WDR61 WD repeat domain 61 0.470262
EIF3C eukaryotic translation initiation factor 3, subunit C 0.131332