CDH3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description cadherin 3, type 1, P-cadherin (placental)|This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1001)
Similar Terms
Downloads & Tools

Genes

312 genes differentially expressed following the CDH3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
DNAAF19 dynein axonemal assembly factor 19 2.8103
IRX1 iroquois homeobox 1 2.8103
SBK3 SH3 domain binding kinase family, member 3 2.8103
C17ORF107 chromosome 17 open reading frame 107 2.8103
ZNF467 zinc finger protein 467 2.8103
TXLNB taxilin beta 2.8103
PRR4 proline rich 4 (lacrimal) 2.8103
BICC1 BicC family RNA binding protein 1 2.8103
SCG2 secretogranin II 2.8103
PRPH peripherin 2.8103
COL17A1 collagen, type XVII, alpha 1 2.8103
SYCP2 synaptonemal complex protein 2 2.8103
MSX2 msh homeobox 2 2.8103
CLDN34 claudin 34 2.8103
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.8103
PCDHA3 protocadherin alpha 3 2.8103
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.8103
ZFP57 ZFP57 zinc finger protein 2.8103
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.8103
CHRD chordin 2.8103
TBX22 T-box 22 2.8103
GPR149 G protein-coupled receptor 149 2.8103
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.755
CCDC116 coiled-coil domain containing 116 2.755
NANOS3 nanos homolog 3 (Drosophila) 2.755
GPR6 G protein-coupled receptor 6 2.755
PI16 peptidase inhibitor 16 2.755
MUC20 mucin 20, cell surface associated 2.755
RGS9BP regulator of G protein signaling 9 binding protein 2.755
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.755
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.755
PRSS41 protease, serine, 41 2.755
ADGB androglobin 2.755
STRA8 stimulated by retinoic acid 8 2.755
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.755
C1ORF146 chromosome 1 open reading frame 146 2.755
OR1L8 olfactory receptor, family 1, subfamily L, member 8 2.755
C1GALT1C1L C1GALT1-specific chaperone 1 like 2.755
IL2RA interleukin 2 receptor, alpha 2.755
TAS2R19 taste receptor, type 2, member 19 2.755
MPL MPL proto-oncogene, thrombopoietin receptor 2.755
UNC45B unc-45 homolog B (C. elegans) 2.755
SLC9C2 solute carrier family 9, member C2 (putative) 2.755
PCDHB1 protocadherin beta 1 2.755
XCL1 chemokine (C motif) ligand 1 2.755
GLYAT glycine-N-acyltransferase 2.755
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.755
PAX2 paired box 2 2.755
OLIG3 oligodendrocyte transcription factor 3 2.755
ASB12 ankyrin repeat and SOCS box containing 12 2.755
PECAM1 platelet/endothelial cell adhesion molecule 1 2.755
TRIM74 tripartite motif containing 74 2.755
MYO16 myosin XVI 2.755
THSD8 thrombospondin type 1 domain containing 8 2.755
CLXN calaxin 2.755
CBLIF cobalamin binding intrinsic factor 2.755
TLE7 TLE family member 7 2.755
RUSF1 RUS family member 1 2.755
GBP1 guanylate binding protein 1, interferon-inducible 2.755
NCKIPSD NCK interacting protein with SH3 domain 2.755
OR56B2 olfactory receptor family 56 subfamily B member 2 2.755
CXCL13 chemokine (C-X-C motif) ligand 13 2.755
CBY2 chibby family member 2 2.755
GSTT4 glutathione S-transferase theta 4 2.755
WASL-DT WASL divergent transcript 2.755
LINC02268 long intergenic non-protein coding RNA 2268 2.755
CPNE8-AS1 CPNE8 antisense RNA 1 2.755
NOTCH2NLB notch 2 N-terminal like B 2.755
H2BK1 H2B.K variant histone 1 2.755
SMIM35 small integral membrane protein 35 2.755
AKAIN1 A-kinase anchor inhibitor 1 2.755
AKR1C8 aldo-keto reductase family 1 member C8 2.755
STMN4 stathmin-like 4 2.755
PDF peptide deformylase (mitochondrial) 2.755
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.755
SPDYC speedy/RINGO cell cycle regulator family member C 2.755
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.755
C1QTNF8 C1q and tumor necrosis factor related protein 8 2.755
SLAMF6 SLAM family member 6 2.755
AWAT2 acyl-CoA wax alcohol acyltransferase 2 2.755
DNASE2B deoxyribonuclease II beta 2.755
GOLGA7B golgin A7 family, member B 2.755
MAG myelin associated glycoprotein 2.755
NPFF neuropeptide FF-amide peptide precursor 2.755
HNF1A HNF1 homeobox A 2.755
ADRB3 adrenoceptor beta 3 2.755
PAPOLB poly(A) polymerase beta (testis specific) 2.755
TREX2 three prime repair exonuclease 2 2.755
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.755
DOK2 docking protein 2, 56kDa 2.755
FCMR Fc fragment of IgM receptor 2.755
TSPAN1 tetraspanin 1 2.755
DYNLRB2 dynein, light chain, roadblock-type 2 2.755
REG4 regenerating islet-derived family, member 4 2.755
MKRN3 makorin ring finger protein 3 2.755
FIGLA folliculogenesis specific basic helix-loop-helix 2.755
MAB21L2 mab-21-like 2 (C. elegans) 2.755
PRSS55 protease, serine, 55 2.755
AICDA activation-induced cytidine deaminase 2.755
OR13A1 olfactory receptor, family 13, subfamily A, member 1 2.755
ZC3H12D zinc finger CCCH-type containing 12D 2.755
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.755
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.755
C9ORF50 chromosome 9 open reading frame 50 2.755
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.755
SIGLEC15 sialic acid binding Ig-like lectin 15 2.755
CARNS1 carnosine synthase 1 2.755
CDH17 cadherin 17, LI cadherin (liver-intestine) 2.755
SPEF1 sperm flagellar 1 2.755
MAGEB17 melanoma antigen family B17 2.755
CST4 cystatin S 2.755
CSTA cystatin A (stefin A) 2.755
HOXD3 homeobox D3 2.755
APOC4 apolipoprotein C-IV 2.755
TCEA3 transcription elongation factor A (SII), 3 2.755
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 2.755
EVPLL envoplakin-like 2.755
DSC1 desmocollin 1 2.755
FBXO39 F-box protein 39 2.755
ZP1 zona pellucida glycoprotein 1 (sperm receptor) 2.755
KRT15 keratin 15, type I 2.755
TEKT1 tektin 1 2.755
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.755
GCM2 glial cells missing homolog 2 (Drosophila) 2.755
DCT dopachrome tautomerase 2.755
TTC24 tetratricopeptide repeat domain 24 2.755
TSSK1B testis-specific serine kinase 1B 2.755
DRC7 dynein regulatory complex subunit 7 2.755
SYT5 synaptotagmin V 2.755
RBP3 retinol binding protein 3, interstitial 2.755
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.755
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.755
ZNF831 zinc finger protein 831 2.755
ERAP2 endoplasmic reticulum aminopeptidase 2 2.755
BHLHA15 basic helix-loop-helix family, member a15 2.755
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.755
GP1BB glycoprotein Ib (platelet), beta polypeptide 2.755
DMRTC1 DMRT-like family C1 2.755
CLEC2A C-type lectin domain family 2, member A 2.755
WNT10B wingless-type MMTV integration site family, member 10B 2.755
OXER1 oxoeicosanoid (OXE) receptor 1 2.755
GRAP2 GRB2-related adaptor protein 2 2.755
CTSS cathepsin S 2.755
RNF148 ring finger protein 148 2.755
PGR progesterone receptor 2.755
CTRB1 chymotrypsinogen B1 2.755
AMDHD1 amidohydrolase domain containing 1 2.755
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.755
BHMT betaine--homocysteine S-methyltransferase 2.755
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.755
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.755
PGPEP1L pyroglutamyl-peptidase I-like 2.755
CELF3 CUGBP, Elav-like family member 3 2.755
IFFO2 intermediate filament family orphan 2 2.71568
LYG2 lysozyme G-like 2 2.66594
GOLGA6C golgin A6 family, member C 2.66594
DPF3 D4, zinc and double PHD fingers, family 3 2.66594
APP amyloid beta (A4) precursor protein 2.60927
MAX MYC associated factor X 2.56991
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.54996
DSE dermatan sulfate epimerase 2.49722
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.46562
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 2.46341
PECR peroxisomal trans-2-enoyl-CoA reductase 2.46341
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 2.46341
XPOT exportin, tRNA 2.42814
GFRA1 GDNF family receptor alpha 1 2.42519
TGFA transforming growth factor, alpha 2.40564
SHISA3 shisa family member 3 2.3877
TNNI3K TNNI3 interacting kinase 2.38256
MCTP2 multiple C2 domains, transmembrane 2 2.36956
VAV2 vav 2 guanine nucleotide exchange factor 2.36079
EYA2 EYA transcriptional coactivator and phosphatase 2 2.36079
ARSL arylsulfatase L 2.35474
DSCAML1 Down syndrome cell adhesion molecule like 1 2.33023
NKAIN2 Na+/K+ transporting ATPase interacting 2 2.32443
SNX33 sorting nexin 33 2.32371
PPP1R3F protein phosphatase 1, regulatory subunit 3F 2.32121
ZNF91 zinc finger protein 91 2.30831
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.3081
PKDCC protein kinase domain containing, cytoplasmic 2.26568
TPBG trophoblast glycoprotein 2.25852
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.25413
FXYD7 FXYD domain containing ion transport regulator 7 2.22901
RPN1 ribophorin I 2.22599
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.18866
MISP3 MISP family member 3 2.17189
EXOC7 exocyst complex component 7 2.17164
ITGB5 integrin, beta 5 2.15211
FANCD2OS FANCD2 opposite strand 2.12154
TUBGCP5 tubulin, gamma complex associated protein 5 2.12151
DCAF8 DDB1 and CUL4 associated factor 8 2.09482
FOXK1 forkhead box K1 2.09103
FMC1 formation of mitochondrial complex V assembly factor 1 homolog 2.07817
TUFM Tu translation elongation factor, mitochondrial 2.07385
TSHZ2 teashirt zinc finger homeobox 2 2.07219
IARS1 isoleucyl-tRNA synthetase 1 2.06152
FER1L5 fer-1-like family member 5 2.04375
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2.04375
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.03725
DNAAF4 dynein axonemal assembly factor 4 2.03196
WWP1 WW domain containing E3 ubiquitin protein ligase 1 2.02757
USP9X ubiquitin specific peptidase 9, X-linked 2.01536
ZSWIM1 zinc finger, SWIM-type containing 1 2.01133
FAM3A family with sequence similarity 3, member A 2.01133

decreased expression

Symbol Name Standardized Value
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.8103
SNPH syntaphilin -2.8103
ZNF324 zinc finger protein 324 -2.8103
MSC musculin -2.755
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 -2.755
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -2.755
POSTN periostin, osteoblast specific factor -2.755
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 -2.755
TDO2 tryptophan 2,3-dioxygenase -2.755
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.755
CD22 CD22 molecule -2.755
ACADL acyl-CoA dehydrogenase, long chain -2.755
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -2.755
KIF12 kinesin family member 12 -2.755
PGM5 phosphoglucomutase 5 -2.755
LAMP3 lysosomal-associated membrane protein 3 -2.755
RPLP1 ribosomal protein, large, P1 -2.755
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -2.755
LOC112694756 uncharaterized LOC112694756 -2.755
HASPIN histone H3 associated protein kinase -2.755
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -2.755
DLEU7 deleted in lymphocytic leukemia, 7 -2.755
FIMP1 fertilization-influencing membrane protein 1 -2.755
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H -2.755
FAM240C family with sequence similarity 240 member C -2.755
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 -2.755
FAM186A family with sequence similarity 186, member A -2.755
MIP major intrinsic protein of lens fiber -2.755
ZNF439 zinc finger protein 439 -2.755
TSSK6 testis-specific serine kinase 6 -2.755
AACS acetoacetyl-CoA synthetase -2.755
SPINK5 serine peptidase inhibitor, Kazal type 5 -2.755
OSGIN1 oxidative stress induced growth inhibitor 1 -2.755
DNAAF6 dynein axonemal assembly factor 6 -2.755
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 -2.755
ADRA2A adrenoceptor alpha 2A -2.755
GJC1 gap junction protein, gamma 1, 45kDa -2.755
FAM209A family with sequence similarity 209, member A -2.755
C2CD4D C2 calcium-dependent domain containing 4D -2.755
NT5DC4 5'-nucleotidase domain containing 4 -2.755
SORCS3 sortilin-related VPS10 domain containing receptor 3 -2.755
OMD osteomodulin -2.755
HMGB4 high mobility group box 4 -2.755
OR56A3 olfactory receptor, family 56, subfamily A, member 3 -2.755
TMIGD2 transmembrane and immunoglobulin domain containing 2 -2.755
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 -2.755
FBXL20 F-box and leucine-rich repeat protein 20 -2.755
NBN nibrin -2.755
F12 coagulation factor XII (Hageman factor) -2.74169
HNRNPA1L3 heterogeneous nuclear ribonucleoprotein A1 like 3 -2.71777
MOB3C MOB kinase activator 3C -2.71568
ASIP agouti signaling protein -2.71568
SCN2A sodium channel, voltage gated, type II alpha subunit -2.71568
ZNF396 zinc finger protein 396 -2.71568
SRRM1 serine/arginine repetitive matrix 1 -2.69301
CDH3 cadherin 3, type 1, P-cadherin (placental) -2.60543
GOLGA1 golgin A1 -2.60387
MYB v-myb avian myeloblastosis viral oncogene homolog -2.60387
HSF5 heat shock transcription factor family member 5 -2.57942
GUCA1A guanylate cyclase activator 1A (retina) -2.56991
RUFY2 RUN and FYVE domain containing 2 -2.56991
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.56991
IFT20 intraflagellar transport 20 -2.54128
RHOU ras homolog family member U -2.50554
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.49272
TLN2 talin 2 -2.45686
MAMLD1 mastermind-like domain containing 1 -2.44723
TDRP testis development related protein -2.38256
SCOC short coiled-coil protein -2.36946
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -2.34845
CERS2 ceramide synthase 2 -2.34153
TMEM250 transmembrane protein 250 -2.31469
PZP pregnancy-zone protein -2.30451
LRRC36 leucine rich repeat containing 36 -2.30451
SCAMP2 secretory carrier membrane protein 2 -2.30451
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 -2.29505
TMEM236 transmembrane protein 236 -2.27652
YPEL1 yippee-like 1 (Drosophila) -2.26914
ARCN1 archain 1 -2.25752
RPL37A ribosomal protein L37a -2.24033
THEM6 thioesterase superfamily member 6 -2.21853
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -2.18866
SNCAIP synuclein, alpha interacting protein -2.18864
FKBP6 FK506 binding protein 6, 36kDa -2.18589
PDGFA platelet-derived growth factor alpha polypeptide -2.17164
KAT6B K(lysine) acetyltransferase 6B -2.15102
PCGF6 polycomb group ring finger 6 -2.15102
ZSWIM7 zinc finger, SWIM-type containing 7 -2.10553
TOR1AIP1 torsin A interacting protein 1 -2.10147
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.09683
DHPS deoxyhypusine synthase -2.09113
DOCK5 dedicator of cytokinesis 5 -2.08168
AQP5 aquaporin 5 -2.07844
GDF5 growth differentiation factor 5 -2.07844
RAE1 ribonucleic acid export 1 -2.07817
CHMP2B charged multivesicular body protein 2B -2.0685
MCM6 minichromosome maintenance complex component 6 -2.04594
LHCGR luteinizing hormone/choriogonadotropin receptor -2.03452
OR14A16 olfactory receptor, family 14, subfamily A, member 16 -2.03283
CARM1 coactivator-associated arginine methyltransferase 1 -2.02955
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.02757
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -2.02757
MAST3 microtubule associated serine/threonine kinase 3 -2.02325
MYO9B myosin IXB -2.02325
NCAPH2 non-SMC condensin II complex, subunit H2 -2.01703
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.01536
ESRP1 epithelial splicing regulatory protein 1 -2.00809