CDH3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cadherin 3, type 1, P-cadherin (placental)|This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1001)
External Link https://ncbi.nlm.nih.gov/gene/1001
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Genes

497 genes differentially expressed following the CDH3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A 0.0153579
CA2 carbonic anhydrase II 0.0146637
KRT14 keratin 14, type I 0.0118543
TFPI2 tissue factor pathway inhibitor 2 0.0113971
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0110876
VAV3 vav 3 guanine nucleotide exchange factor 0.00903694
NT5E 5'-nucleotidase, ecto (CD73) 0.00882101
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00871062
FOLR1 folate receptor 1 (adult) 0.00854369
AZU1 azurocidin 1 0.00851884
STC2 stanniocalcin 2 0.00831123
SLPI secretory leukocyte peptidase inhibitor 0.00822555
ELANE elastase, neutrophil expressed 0.00800987
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00800938
PRSS21 protease, serine, 21 (testisin) 0.00774184
SNAI2 snail family zinc finger 2 0.00759186
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0075734
S100A8 S100 calcium binding protein A8 0.00751869
RIPK2 receptor-interacting serine-threonine kinase 2 0.00724473
CRYAB crystallin, alpha B 0.00701204
CXCL8 chemokine (C-X-C motif) ligand 8 0.00695572
KYNU kynureninase 0.00686886
SCGB2A1 secretoglobin, family 2A, member 1 0.00683696
INHBA inhibin, beta A 0.00683317
PRTN3 proteinase 3 0.00680577
SOD2 superoxide dismutase 2, mitochondrial 0.00669586
SPRED2 sprouty-related, EVH1 domain containing 2 0.00664521
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00662016
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00658699
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00657949
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00655118
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00650088
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00647993
SOX9 SRY (sex determining region Y)-box 9 0.00647766
HTRA1 HtrA serine peptidase 1 0.00645634
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00641449
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00632838
RNF167 ring finger protein 167 0.00619023
IL1B interleukin 1, beta 0.00618062
TSPYL5 TSPY-like 5 0.00615081
CCL20 chemokine (C-C motif) ligand 20 0.00613582
KRT17 keratin 17, type I 0.00611597
RNASE3 ribonuclease, RNase A family, 3 0.00608318
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00595298
BASP1 brain abundant, membrane attached signal protein 1 0.00593958
S100A9 S100 calcium binding protein A9 0.00591527
ATF3 activating transcription factor 3 0.00590319
REEP5 receptor accessory protein 5 0.00588617
TXLNA taxilin alpha 0.00580136
KLK11 kallikrein-related peptidase 11 0.00578463
THBS1 thrombospondin 1 0.00576075
PERP PERP, TP53 apoptosis effector 0.00575856
RGS4 regulator of G-protein signaling 4 0.00575361
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00575338
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00570858
KLK10 kallikrein-related peptidase 10 0.0057057
TSPAN8 tetraspanin 8 0.00565907
IRS2 insulin receptor substrate 2 0.00563202
ARMCX3 armadillo repeat containing, X-linked 3 0.00561867
ZFP36 ZFP36 ring finger protein 0.00559579
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00559574
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00557819
CTSG cathepsin G 0.00556879
DEFA4 defensin, alpha 4, corticostatin 0.00555069
RGCC regulator of cell cycle 0.00553616
DMAC2L distal membrane arm assembly component 2 like 0.00551107
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.0054836
BPI bactericidal/permeability-increasing protein 0.0054612
NVL nuclear VCP-like 0.0054216
ODC1 ornithine decarboxylase 1 0.00536075
RFTN1 raftlin, lipid raft linker 1 0.00534566
CXCL5 chemokine (C-X-C motif) ligand 5 0.00533572
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00533526
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.00530237
KCTD12 potassium channel tetramerization domain containing 12 0.00528056
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00526359
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00522726
LCN2 lipocalin 2 0.0052208
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.00521759
GRAMD2B GRAM domain containing 2B 0.00519498
KRT15 keratin 15, type I 0.00517958
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.0051505
KLF9 Kruppel-like factor 9 0.00513975
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.00513685
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00513066
TM4SF1 transmembrane 4 L six family member 1 0.00510748
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.00509571
KRT5 keratin 5, type II 0.00509365
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00508677
LITAF lipopolysaccharide-induced TNF factor 0.00508486
JUNB jun B proto-oncogene 0.00507495
FRS2 fibroblast growth factor receptor substrate 2 0.0050451
DEFB1 defensin, beta 1 0.00503198
AQP3 aquaporin 3 (Gill blood group) 0.00503118
OLFML2A olfactomedin-like 2A 0.00502725
CALCA calcitonin-related polypeptide alpha 0.00501666
SGK1 serum/glucocorticoid regulated kinase 1 0.00500659
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.00500579
SPRY2 sprouty homolog 2 (Drosophila) 0.00500532
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00499264
TENT5A terminal nucleotidyltransferase 5A 0.00496867
JAG1 jagged 1 0.0049657
PER1 period circadian clock 1 0.00495764
BCL2A1 BCL2-related protein A1 0.00494393
BMP2 bone morphogenetic protein 2 0.0049217
SOCS2 suppressor of cytokine signaling 2 0.00490384
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00490169
CAB39 calcium binding protein 39 0.00489566
NDRG2 NDRG family member 2 0.00486976
LAMB3 laminin, beta 3 0.00485611
FGF1 fibroblast growth factor 1 (acidic) 0.00485563
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00485356
HIST1H2BD histone cluster 1, H2bd 0.00480579
MARCHF6 membrane associated ring-CH-type finger 6 0.00479561
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00477399
PITX3 paired-like homeodomain 3 0.00477251
HMOX1 heme oxygenase 1 0.00476905
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00476877
MXRA8 matrix-remodelling associated 8 0.00475293
TIMP3 TIMP metallopeptidase inhibitor 3 0.00473267
PTGES prostaglandin E synthase 0.00470481
MMP8 matrix metallopeptidase 8 0.00469612
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00468199
CYBB cytochrome b-245, beta polypeptide 0.00467787
PARP8 poly (ADP-ribose) polymerase family, member 8 0.00467231
ARMCX6 armadillo repeat containing, X-linked 6 0.00466785
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0046624
TUBA4A tubulin, alpha 4a 0.00465742
IER5 immediate early response 5 0.00465097
NEO1 neogenin 1 0.00463526
IL1RN interleukin 1 receptor antagonist 0.0046332
CDK14 cyclin-dependent kinase 14 0.00463016
DSP desmoplakin 0.00462448
TESC tescalcin 0.00462202
CAPN1 calpain 1, (mu/I) large subunit 0.00461591
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00461501
PI3 peptidase inhibitor 3, skin-derived 0.00459788
CPE carboxypeptidase E 0.00459458
ZNF281 zinc finger protein 281 0.00459355
TBXA2R thromboxane A2 receptor 0.00459328
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00458558
CLEC11A C-type lectin domain family 11, member A 0.00457146
PTK2B protein tyrosine kinase 2 beta 0.00456679
MFAP3L microfibrillar-associated protein 3-like 0.00456552
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00456343
PLEK pleckstrin 0.00456303
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00455916
COCH cochlin 0.00453841
NFE2L2 nuclear factor, erythroid 2-like 2 0.0045352
SLC38A2 solute carrier family 38, member 2 0.00452551
JMJD6 jumonji domain containing 6 0.00452304
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00452231
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00449922
IVNS1ABP influenza virus NS1A binding protein 0.00449634
FAM107A family with sequence similarity 107, member A 0.0044864
HIST1H2AC histone cluster 1, H2ac 0.00447999
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00446635
AOC1 amine oxidase, copper containing 1 0.00446183
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00445672
DNM1L dynamin 1-like 0.0044407
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00443412
PMP2 peripheral myelin protein 2 0.00442504
SGPP1 sphingosine-1-phosphate phosphatase 1 0.004407
ELF4 E74-like factor 4 (ets domain transcription factor) 0.0044055
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00438352
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.0043833
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00436867
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.00436131
PDE4B phosphodiesterase 4B, cAMP-specific 0.00434712
SORT1 sortilin 1 0.00433979
ABHD6 abhydrolase domain containing 6 0.00433897
PFDN6 prefoldin subunit 6 0.00433165
GADD45B growth arrest and DNA-damage-inducible, beta 0.00430439
SATB2 SATB homeobox 2 0.00430344
DIPK1A divergent protein kinase domain 1A 0.00430311
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00430041
BEX4 brain expressed, X-linked 4 0.00429744
XBP1 X-box binding protein 1 0.00425692
ZC3H12A zinc finger CCCH-type containing 12A 0.00425346
MYO1B myosin IB 0.0042454
BAX BCL2-associated X protein 0.00424114
RGS16 regulator of G-protein signaling 16 0.00422521
FOXC1 forkhead box C1 0.00420182
MMP9 matrix metallopeptidase 9 0.00419442
WWC1 WW and C2 domain containing 1 0.00418323
CST7 cystatin F (leukocystatin) 0.00417718
RGS1 regulator of G-protein signaling 1 0.00417563
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00416939
MPC1 mitochondrial pyruvate carrier 1 0.00416008
RAB29 RAB29, member RAS oncogene family 0.00415279
PTPRK protein tyrosine phosphatase, receptor type, K 0.00414727
RIPK4 receptor-interacting serine-threonine kinase 4 0.00413568
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 0.00413327
ASS1 argininosuccinate synthase 1 0.00413064
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00412636
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.00412323
LYRM2 LYR motif containing 2 0.00412231
CRLF1 cytokine receptor-like factor 1 0.00411747
ADD3 adducin 3 (gamma) 0.00411695
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.00411399
TSPO translocator protein (18kDa) 0.00410668
MXI1 MAX interactor 1, dimerization protein 0.00410294
RPL26L1 ribosomal protein L26-like 1 0.00410136
EHF ets homologous factor 0.00409888
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00409015
CHKA choline kinase alpha 0.00408823
EGR1 early growth response 1 0.004088
FN1 fibronectin 1 0.00408775
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00406556
ACOT9 acyl-CoA thioesterase 9 0.0040634
SS18 synovial sarcoma translocation, chromosome 18 0.00405234
TP53BP2 tumor protein p53 binding protein 2 0.00405045
CAPN3 calpain 3, (p94) 0.00404321
ALCAM activated leukocyte cell adhesion molecule 0.00404078
OSTF1 osteoclast stimulating factor 1 0.00403531
PILRB paired immunoglobin-like type 2 receptor beta 0.00402583
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.00401546
KRT16 keratin 16, type I 0.00400549
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00399435
ATP5PB ATP synthase peripheral stalk-membrane subunit b 0.00399131
ADM adrenomedullin 0.00398852
THBD thrombomodulin 0.00398445
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00397234
LIF leukemia inhibitory factor 0.00396423
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00394213
KLHL21 kelch-like family member 21 0.00393676
AK2 adenylate kinase 2 0.00392034
SCP2 sterol carrier protein 2 0.00392012
NCF1C neutrophil cytosolic factor 1C pseudogene 0.00391428
RTCA RNA 3'-terminal phosphate cyclase 0.00391324
PTPRE protein tyrosine phosphatase, receptor type, E 0.00391274
GOLT1B golgi transport 1B 0.00390909
ASCL1 achaete-scute family bHLH transcription factor 1 0.00390224
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00390018
ADK adenosine kinase 0.00387453
RNFT1 ring finger protein, transmembrane 1 0.00386208
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00385874
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.00385504
CHD7 chromodomain helicase DNA binding protein 7 0.00384779
TGFA transforming growth factor, alpha 0.00384734
RGS2 regulator of G-protein signaling 2 0.00384058
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00383697
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.00383433
CRISP3 cysteine-rich secretory protein 3 0.00382791
MMP7 matrix metallopeptidase 7 0.00382538
PEG10 paternally expressed 10 0.00382503
HAS1 hyaluronan synthase 1 0.00382461
NDC1 NDC1 transmembrane nucleoporin 0.0038237

decreased expression

Symbol Name Standardized Value
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0119268
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0113873
BMP4 bone morphogenetic protein 4 -0.00965392
PBX1 pre-B-cell leukemia homeobox 1 -0.00960607
HOXB2 homeobox B2 -0.00825774
AGR2 anterior gradient 2 -0.00794414
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0077761
SEPP1 selenoprotein P, plasma, 1 -0.00776392
FGFR1 fibroblast growth factor receptor 1 -0.00770667
C8ORF4 chromosome 8 open reading frame 4 -0.00755121
MYO5C myosin VC -0.00732796
GPX2 glutathione peroxidase 2 -0.00718194
SUB1 SUB1 homolog (S. cerevisiae) -0.00707014
GSTA4 glutathione S-transferase alpha 4 -0.00704443
VWF von Willebrand factor -0.006862
CRIP1 cysteine-rich protein 1 (intestinal) -0.00685923
TMSB15A thymosin beta 15a -0.00681295
CPA3 carboxypeptidase A3 (mast cell) -0.00671954
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0067058
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00668992
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00667633
DDHD2 DDHD domain containing 2 -0.0065601
IFITM1 interferon induced transmembrane protein 1 -0.00653146
LEF1 lymphoid enhancer-binding factor 1 -0.0064906
NEBL nebulette -0.00647442
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00645766
CDCA4 cell division cycle associated 4 -0.00638477
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00632583
HEATR1 HEAT repeat containing 1 -0.00628233
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00622126
DACH1 dachshund family transcription factor 1 -0.00617263
SFRP1 secreted frizzled-related protein 1 -0.00614833
CETN2 centrin, EF-hand protein, 2 -0.00614583
AKR1C3 aldo-keto reductase family 1, member C3 -0.00614128
PCNA proliferating cell nuclear antigen -0.00612585
LYZ lysozyme -0.00606903
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00605175
MDFIC MyoD family inhibitor domain containing -0.00603081
MAN1C1 mannosidase, alpha, class 1C, member 1 -0.00596831
BAMBI BMP and activin membrane-bound inhibitor -0.00596134
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00594364
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00592065
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00589567
TFF1 trefoil factor 1 -0.00588214
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00587504
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00586359
PCGF2 polycomb group ring finger 2 -0.0058499
MTCL1 microtubule crosslinking factor 1 -0.00580531
SELL selectin L -0.00580361
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00575228
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -0.00574626
RAB15 RAB15, member RAS oncogene family -0.00574433
CLU clusterin -0.00572913
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00570498
AQP1 aquaporin 1 (Colton blood group) -0.00568708
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00567023
HOXB6 homeobox B6 -0.00566617
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00563634
CHRDL1 chordin-like 1 -0.00563471
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0056033
NTS neurotensin -0.00560115
TST thiosulfate sulfurtransferase (rhodanese) -0.00557474
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00554554
NANOG Nanog homeobox -0.00553406
MMP2 matrix metallopeptidase 2 -0.00553169
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00551785
IL13RA2 interleukin 13 receptor, alpha 2 -0.00548399
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0054716
IL7R interleukin 7 receptor -0.00545729
CFI complement factor I -0.00544877
SFTPC surfactant protein C -0.00544269
MICU2 mitochondrial calcium uptake 2 -0.00543848
DLK1 delta-like 1 homolog (Drosophila) -0.00542235
ACACA acetyl-CoA carboxylase alpha -0.00540948
MX1 MX dynamin-like GTPase 1 -0.00538836
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.0053777
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00536733
TSPAN13 tetraspanin 13 -0.00535709
CCR2 chemokine (C-C motif) receptor 2 -0.00527167
ECI2 enoyl-CoA delta isomerase 2 -0.00526422
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00526367
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00521657
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00519993
COL14A1 collagen, type XIV, alpha 1 -0.0051907
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00518328
SFTPA2 surfactant protein A2 -0.00517068
HYOU1 hypoxia up-regulated 1 -0.00515222
NPTX2 neuronal pentraxin II -0.00513062
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00512937
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00512661
AMPH amphiphysin -0.00512292
COL1A2 collagen, type I, alpha 2 -0.00508805
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.005087
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0050786
SPON1 spondin 1, extracellular matrix protein -0.00506261
CTSH cathepsin H -0.00506208
CCL19 chemokine (C-C motif) ligand 19 -0.00505546
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00505529
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00505122
SDC1 syndecan 1 -0.00504419
PDGFA platelet-derived growth factor alpha polypeptide -0.00504056
UNG uracil-DNA glycosylase -0.00502873
UFM1 ubiquitin-fold modifier 1 -0.0050127
NID1 nidogen 1 -0.00500265
EVL Enah/Vasp-like -0.00496806
KDM5D lysine (K)-specific demethylase 5D -0.00496528
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00495176
GIMAP4 GTPase, IMAP family member 4 -0.00494034
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00493548
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00493289
TRIM14 tripartite motif containing 14 -0.00491003
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00490481
MERTK MER proto-oncogene, tyrosine kinase -0.00488911
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00487987
FGF9 fibroblast growth factor 9 -0.00486606
IL33 interleukin 33 -0.00486116
DPYSL3 dihydropyrimidinase-like 3 -0.00485588
LAMA4 laminin, alpha 4 -0.00483817
CD36 CD36 molecule (thrombospondin receptor) -0.00483376
AZF1 azoospermia factor 1 -0.00482803
C7 complement component 7 -0.00482027
TPBG trophoblast glycoprotein -0.00481458
FLI1 Fli-1 proto-oncogene, ETS transcription factor -0.00481287
GATA2 GATA binding protein 2 -0.00480139
PRR5 proline rich 5 (renal) -0.00479793
EPHB2 EPH receptor B2 -0.00479665
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00479068
DCPS decapping enzyme, scavenger -0.00477361
ENO2 enolase 2 (gamma, neuronal) -0.00477173
CHN2 chimerin 2 -0.00475495
REG3A regenerating islet-derived 3 alpha -0.0047538
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00474774
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00473607
NDN necdin, melanoma antigen (MAGE) family member -0.00473529
TYMS thymidylate synthetase -0.00472556
CDC20 cell division cycle 20 -0.00471648
GIMAP6 GTPase, IMAP family member 6 -0.00471583
CRIP2 cysteine-rich protein 2 -0.00468802
CNR1 cannabinoid receptor 1 (brain) -0.00468093
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.0046795
GPR171 G protein-coupled receptor 171 -0.0046533
CFH complement factor H -0.00464944
ACD adrenocortical dysplasia homolog (mouse) -0.00463806
RNF144A ring finger protein 144A -0.00463318
PON2 paraoxonase 2 -0.00463122
ITK IL2-inducible T-cell kinase -0.00460855
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.0045922
AKR1C1 aldo-keto reductase family 1, member C1 -0.0045863
CLSTN1 calsyntenin 1 -0.00458194
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00458051
DSTN destrin (actin depolymerizing factor) -0.00457936
FANCL Fanconi anemia, complementation group L -0.0045576
NDNF neuron-derived neurotrophic factor -0.00450509
FOXG1 forkhead box G1 -0.00449987
ARMT1 acidic residue methyltransferase 1 -0.00448818
DST dystonin -0.004488
MRPS30 mitochondrial ribosomal protein S30 -0.00448305
TNNT1 troponin T type 1 (skeletal, slow) -0.00447807
WDR61 WD repeat domain 61 -0.00447652
AOC3 amine oxidase, copper containing 3 -0.0044755
CEP170 centrosomal protein 170kDa -0.00446737
SAP18 Sin3A-associated protein, 18kDa -0.00446647
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00444727
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00444098
SETMAR SET domain and mariner transposase fusion gene -0.00443328
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00443256
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.00441263
USP48 ubiquitin specific peptidase 48 -0.0044119
IFT81 intraflagellar transport 81 -0.00437478
MDK midkine (neurite growth-promoting factor 2) -0.00437458
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -0.00437288
MAMLD1 mastermind-like domain containing 1 -0.00437159
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00436624
SPAG16 sperm associated antigen 16 -0.00436541
LACTB2 lactamase, beta 2 -0.00436407
RGS5 regulator of G-protein signaling 5 -0.00434876
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00434348
CADPS2 Ca++-dependent secretion activator 2 -0.00433843
PLAT plasminogen activator, tissue -0.00433711
CPQ carboxypeptidase Q -0.00433049
CERK ceramide kinase -0.00432807
RBPMS RNA binding protein with multiple splicing -0.0043279
L1TD1 LINE-1 type transposase domain containing 1 -0.00432722
SFTPD surfactant protein D -0.00432334
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.00431767
FBP1 fructose-1,6-bisphosphatase 1 -0.00430765
DNTT DNA nucleotidylexotransferase -0.00430431
MRTFB myocardin related transcription factor B -0.00430421
FKBP11 FK506 binding protein 11, 19 kDa -0.00428153
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00427243
FBL fibrillarin -0.00426046
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00425497
COL5A2 collagen, type V, alpha 2 -0.00424717
CCNB2 cyclin B2 -0.00424566
FBXL7 F-box and leucine-rich repeat protein 7 -0.00424405
H2AX H2A.X variant histone -0.00423838
CAVIN2 caveolae associated protein 2 -0.00423315
JAM3 junctional adhesion molecule 3 -0.00422869
RHOT1 ras homolog family member T1 -0.00421563
RAB11A RAB11A, member RAS oncogene family -0.00421439
IRF2 interferon regulatory factor 2 -0.00420917
CRYBG1 crystallin beta-gamma domain containing 1 -0.00419746
TPD52 tumor protein D52 -0.00419301
CDO1 cysteine dioxygenase type 1 -0.00418951
CTSK cathepsin K -0.004189
COTL1 coactosin-like F-actin binding protein 1 -0.00418549
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00418483
NPM3 nucleophosmin/nucleoplasmin 3 -0.00418454
DGLUCY D-glutamate cyclase -0.00417443
CPVL carboxypeptidase, vitellogenic-like -0.00417327
PGD phosphogluconate dehydrogenase -0.00416027
COPS7A COP9 signalosome subunit 7A -0.00415595
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00414843
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -0.00413665
NT5DC2 5'-nucleotidase domain containing 2 -0.00413218
POR P450 (cytochrome) oxidoreductase -0.00413206
THY1 Thy-1 cell surface antigen -0.00413006
KDM3A lysine (K)-specific demethylase 3A -0.00412328
ACSF2 acyl-CoA synthetase family member 2 -0.00412167
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00412154
SACS sacsin molecular chaperone -0.00411832
C1ORF115 chromosome 1 open reading frame 115 -0.00411763
BGN biglycan -0.00410366
WNK1 WNK lysine deficient protein kinase 1 -0.00409552
HOPX HOP homeobox -0.00409529
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00409138
SORD sorbitol dehydrogenase -0.00409133
ITGA8 integrin, alpha 8 -0.00408153
DSE dermatan sulfate epimerase -0.00407791
FXYD3 FXYD domain containing ion transport regulator 3 -0.00406901
KMT2A lysine (K)-specific methyltransferase 2A -0.00406855
NMT2 N-myristoyltransferase 2 -0.00406781
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00406564
DIO2 deiodinase, iodothyronine, type II -0.00406351
F5 coagulation factor V (proaccelerin, labile factor) -0.00405846
TRIP13 thyroid hormone receptor interactor 13 -0.00405373
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00405308
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00403928
EDN3 endothelin 3 -0.00403647
MAST2 microtubule associated serine/threonine kinase 2 -0.00402375
MYH10 myosin, heavy chain 10, non-muscle -0.00402325
MEOX2 mesenchyme homeobox 2 -0.00402019
PADI3 peptidyl arginine deiminase, type III -0.00401854
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00400973
ASPH aspartate beta-hydroxylase -0.00399349
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00398773
NIPSNAP2 nipsnap homolog 2 -0.00397315
AKR1C2 aldo-keto reductase family 1, member C2 -0.00396041
KRT18 keratin 18, type I -0.00394525