CDH3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cadherin 3, type 1, P-cadherin (placental)|This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1001)
External Link http://www.ncbi.nlm.nih.gov/gene/1001
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Genes

60 interacting proteins for CDH3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAK1 AP2 associated kinase 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APH1B APH1B gamma secretase subunit
BCR breakpoint cluster region
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTNND2 catenin (cadherin-associated protein), delta 2
EGFR epidermal growth factor receptor
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
FCHO2 FCH domain only 2
FER fer (fps/fes related) tyrosine kinase
FYN FYN proto-oncogene, Src family tyrosine kinase
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
IGF1R insulin-like growth factor 1 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
JUP junction plakoglobin
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MEA1 male-enhanced antigen 1
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP20 matrix metallopeptidase 20
MMP21 matrix metallopeptidase 21
MMP23B matrix metallopeptidase 23B
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MMP27 matrix metallopeptidase 27
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
NCSTN nicastrin
NECAP2 NECAP endocytosis associated 2
NUMB numb homolog (Drosophila)
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTPN1 protein tyrosine phosphatase, non-receptor type 1
REPS1 RALBP1 associated Eps domain containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
UBC ubiquitin C
YAP1 Yes-associated protein 1