CDH5 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description cadherin 5, type 2 (vascular endothelium)|This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1003)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GCM_CDH5
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Genes

35 co-expressed genes for CDH5 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGER advanced glycosylation end product-specific receptor
APOC3 apolipoprotein C-III
AVPR1B arginine vasopressin receptor 1B
CALCRL calcitonin receptor-like
CCR9 chemokine (C-C motif) receptor 9
CD8B CD8b molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CHIC1 cysteine-rich hydrophobic domain 1
COL14A1 collagen, type XIV, alpha 1
CSN3 casein kappa
CTLA4 cytotoxic T-lymphocyte-associated protein 4
FANCC Fanconi anemia, complementation group C
FEV FEV (ETS oncogene family)
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GH2 growth hormone 2
HCG8 HLA complex group 8
HMGA2 high mobility group AT-hook 2
IFNA21 interferon, alpha 21
ITSN1 intersectin 1 (SH3 domain protein)
KRT32 keratin 32, type I
LYST lysosomal trafficking regulator
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MVK mevalonate kinase
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PTPRU protein tyrosine phosphatase, receptor type, U
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
ZNF8 zinc finger protein 8