CDK1 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description cyclin-dependent kinase 1|The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 983)
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Genes

100 substrates of the kinase CDK1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
IRS4 insulin receptor substrate 4
USP24 ubiquitin specific peptidase 24
FMNL1 formin-like 1
EPN1 epsin 1
ZCCHC8 zinc finger, CCHC domain containing 8
RBM15 RNA binding motif protein 15
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
DNM3 dynamin 3
COL7A1 collagen, type VII, alpha 1
FOXL2 forkhead box L2
MAP3K6 mitogen-activated protein kinase kinase kinase 6
INPPL1 inositol polyphosphate phosphatase-like 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
MAP7D2 MAP7 domain containing 2
UBE2S ubiquitin-conjugating enzyme E2S
CRY2 cryptochrome circadian clock 2
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
KMT2B lysine (K)-specific methyltransferase 2B
PLCH1 phospholipase C, eta 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
EHBP1 EH domain binding protein 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
TAOK2 TAO kinase 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
SNAPIN SNAP-associated protein
ZMYM3 zinc finger, MYM-type 3
ADD3 adducin 3 (gamma)
ADD2 adducin 2 (beta)
STMN1 stathmin 1
PDS5B PDS5 cohesin associated factor B
RSBN1L round spermatid basic protein 1-like
SEC62 SEC62 homolog (S. cerevisiae)
VGLL4 vestigial-like family member 4
CNOT10 CCR4-NOT transcription complex, subunit 10
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
E2F4 E2F transcription factor 4, p107/p130-binding
NKX2-4 NK2 homeobox 4
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
FAM178B family with sequence similarity 178, member B
VASH1 vasohibin 1
CCDC97 coiled-coil domain containing 97
GAREM GRB2 associated, regulator of MAPK1
PRR11 proline rich 11
LENG8 leukocyte receptor cluster (LRC) member 8
PHIP pleckstrin homology domain interacting protein
ILF3 interleukin enhancer binding factor 3, 90kDa
ZNF335 zinc finger protein 335
KIAA1217 KIAA1217
EMILIN1 elastin microfibril interfacer 1
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
BCOR BCL6 corepressor
KRI1 KRI1 homolog (S. cerevisiae)
PROSER3 proline and serine rich 3
NIPBL Nipped-B homolog (Drosophila)
BUD13 BUD13 homolog (S. cerevisiae)
RB1 retinoblastoma 1
MAP4 microtubule-associated protein 4
DNLZ DNL-type zinc finger
PTHLH parathyroid hormone-like hormone
MGA MGA, MAX dimerization protein
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
KIAA1522 KIAA1522
HIST1H1E histone cluster 1, H1e
NCOA2 nuclear receptor coactivator 2
USP6NL USP6 N-terminal like
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTA3 glutathione S-transferase alpha 3
RSL1D1 ribosomal L1 domain containing 1
SRRM2 serine/arginine repetitive matrix 2
THEMIS thymocyte selection associated
FNDC3A fibronectin type III domain containing 3A
BEGAIN brain-enriched guanylate kinase-associated
NOP9 NOP9 nucleolar protein
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
SPEG SPEG complex locus
UBE2I ubiquitin-conjugating enzyme E2I
PELP1 proline, glutamate and leucine rich protein 1
PKN3 protein kinase N3
CIC capicua transcriptional repressor
DMWD dystrophia myotonica, WD repeat containing
BRAF B-Raf proto-oncogene, serine/threonine kinase
PPP1R12C protein phosphatase 1, regulatory subunit 12C
RSBN1 round spermatid basic protein 1
COIL coilin
MBOAT7 membrane bound O-acyltransferase domain containing 7
CASS4 Cas scaffolding protein family member 4
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
HDLBP high density lipoprotein binding protein
ZNF385A zinc finger protein 385A
TNRC18 trinucleotide repeat containing 18
PPP1R3D protein phosphatase 1, regulatory subunit 3D
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
MKI67 marker of proliferation Ki-67