| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin-dependent kinase 1|The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 983) |
| External Link | https://ncbi.nlm.nih.gov/gene/983 |
| Similar Terms | |
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499 genes differentially expressed following the CDK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SFRP1 | secreted frizzled-related protein 1 | 0.0183852 |
| MT1E | metallothionein 1E | 0.0158774 |
| MT1G | metallothionein 1G | 0.01511 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0151098 |
| MT1F | metallothionein 1F | 0.0148247 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.014717 |
| MT1X | metallothionein 1X | 0.0140566 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0139497 |
| AOC1 | amine oxidase, copper containing 1 | 0.0137365 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0135581 |
| MT1H | metallothionein 1H | 0.0135414 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.01319 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0130368 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0126821 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0125293 |
| MT1M | metallothionein 1M | 0.0123861 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0120085 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.011651 |
| MX1 | MX dynamin-like GTPase 1 | 0.0115802 |
| CRYAB | crystallin, alpha B | 0.0115689 |
| GPX3 | glutathione peroxidase 3 | 0.0113878 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0113506 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0111757 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.0110366 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0109065 |
| BMP2 | bone morphogenetic protein 2 | 0.0108689 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0108507 |
| CD59 | CD59 molecule, complement regulatory protein | 0.010829 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0108276 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0107657 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0107616 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0106615 |
| GRN | granulin | 0.010289 |
| MALL | mal, T-cell differentiation protein-like | 0.010271 |
| ADD3 | adducin 3 (gamma) | 0.0101991 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0101224 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00993352 |
| TRIM22 | tripartite motif containing 22 | 0.00989292 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00976736 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00958386 |
| IFI44L | interferon-induced protein 44-like | 0.0093711 |
| FN1 | fibronectin 1 | 0.00933596 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00933567 |
| LBH | limb bud and heart development | 0.00924625 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00924485 |
| SP110 | SP110 nuclear body protein | 0.00922343 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00921887 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00901289 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00892814 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00890775 |
| PITX3 | paired-like homeodomain 3 | 0.00890546 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00886508 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0088328 |
| RBM47 | RNA binding motif protein 47 | 0.00877571 |
| CTSS | cathepsin S | 0.00875793 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00872558 |
| RGS4 | regulator of G-protein signaling 4 | 0.00869339 |
| LXN | latexin | 0.00866609 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00862443 |
| IL1B | interleukin 1, beta | 0.00862122 |
| ANXA1 | annexin A1 | 0.00860263 |
| MVP | major vault protein | 0.008602 |
| SMAD3 | SMAD family member 3 | 0.0085054 |
| SP100 | SP100 nuclear antigen | 0.00848229 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00846896 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00841913 |
| PENK | proenkephalin | 0.00840946 |
| AREG | amphiregulin | 0.00839088 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00830707 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00828053 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00826757 |
| TMEM59 | transmembrane protein 59 | 0.00825479 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00825312 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00824366 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00821791 |
| LCN2 | lipocalin 2 | 0.00810187 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0080772 |
| STC2 | stanniocalcin 2 | 0.00804507 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00803418 |
| MGP | matrix Gla protein | 0.00801375 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00799352 |
| NMRK1 | nicotinamide riboside kinase 1 | 0.00799117 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00797086 |
| OPN3 | opsin 3 | 0.00796466 |
| KRT15 | keratin 15, type I | 0.00792467 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00792073 |
| CLCA4 | chloride channel accessory 4 | 0.00789177 |
| COBL | cordon-bleu WH2 repeat protein | 0.0078866 |
| SIRPA | signal-regulatory protein alpha | 0.00787028 |
| MT2A | metallothionein 2A | 0.00779084 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00777082 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00776904 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00774244 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00773504 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00771883 |
| AK1 | adenylate kinase 1 | 0.007709 |
| CLTB | clathrin, light chain B | 0.00769895 |
| TSPAN1 | tetraspanin 1 | 0.00769725 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00768013 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00767621 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00760257 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00759566 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0075871 |
| OPHN1 | oligophrenin 1 | 0.00756215 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00755017 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00754689 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00752984 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00749813 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00749245 |
| TNS3 | tensin 3 | 0.00747642 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00743867 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00742935 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00741667 |
| ECM1 | extracellular matrix protein 1 | 0.00737781 |
| IL7R | interleukin 7 receptor | 0.00737533 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00737138 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00734936 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.00734182 |
| GM2A | GM2 ganglioside activator | 0.00731618 |
| MYO1C | myosin IC | 0.00730784 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00730767 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0072931 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00724219 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00723221 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00723009 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00720963 |
| TSPAN3 | tetraspanin 3 | 0.00720593 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0071986 |
| TSPAN8 | tetraspanin 8 | 0.00718552 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00717422 |
| KLK10 | kallikrein-related peptidase 10 | 0.00717233 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0071238 |
| SP140L | SP140 nuclear body protein-like | 0.00711688 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.0070901 |
| EPCAM | epithelial cell adhesion molecule | 0.00708418 |
| SERINC3 | serine incorporator 3 | 0.00707867 |
| RCAN1 | regulator of calcineurin 1 | 0.00706248 |
| CCNB2 | cyclin B2 | 0.00705752 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00705221 |
| IL6 | interleukin 6 | 0.00704787 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00703913 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00701496 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00698225 |
| EPS8L2 | EPS8-like 2 | 0.00697757 |
| FABP1 | fatty acid binding protein 1, liver | 0.00697446 |
| MAL | mal, T-cell differentiation protein | 0.00696061 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00695341 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.0069042 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00690135 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00686563 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00686219 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 0.00685759 |
| MYBPC1 | myosin binding protein C, slow type | 0.00680784 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00680371 |
| LPIN1 | lipin 1 | 0.0067869 |
| CTSB | cathepsin B | 0.00677221 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.00677041 |
| KLK11 | kallikrein-related peptidase 11 | 0.00676239 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.0067551 |
| CENPE | centromere protein E, 312kDa | 0.00675338 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00674304 |
| CFI | complement factor I | 0.00673942 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00671717 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00671157 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00669221 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00668655 |
| ITM2C | integral membrane protein 2C | 0.00668469 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00668294 |
| MYOF | myoferlin | 0.00667238 |
| ITGA6 | integrin, alpha 6 | 0.00664917 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00664727 |
| CD9 | CD9 molecule | 0.00664224 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00663505 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00662546 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00660744 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00659885 |
| LEPROT | leptin receptor overlapping transcript | 0.0065833 |
| MX2 | MX dynamin-like GTPase 2 | 0.00658182 |
| EMP1 | epithelial membrane protein 1 | 0.00657862 |
| S100A10 | S100 calcium binding protein A10 | 0.00656773 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00656744 |
| COL9A3 | collagen, type IX, alpha 3 | 0.0065409 |
| HLA-B | major histocompatibility complex, class I, B | 0.00651778 |
| CD44 | CD44 molecule (Indian blood group) | 0.0065128 |
| CLIC5 | chloride intracellular channel 5 | 0.00651077 |
| PXDN | peroxidasin | 0.00648962 |
| ATF3 | activating transcription factor 3 | 0.00647274 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00643308 |
| THBS1 | thrombospondin 1 | 0.00642814 |
| TDRD7 | tudor domain containing 7 | 0.00641192 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00640419 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00639245 |
| SLC16A4 | solute carrier family 16, member 4 | 0.00638968 |
| ATP9A | ATPase, class II, type 9A | 0.00638494 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00638402 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00637851 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00637776 |
| LIF | leukemia inhibitory factor | 0.00634721 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00633485 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00632758 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00632473 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00631393 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00629784 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00629436 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00627889 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.00627834 |
| LPXN | leupaxin | 0.00624774 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00623237 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00621935 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00621392 |
| BMP7 | bone morphogenetic protein 7 | 0.00619935 |
| BEX1 | brain expressed, X-linked 1 | 0.00616884 |
| IFI44 | interferon-induced protein 44 | 0.0061606 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00615284 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00615092 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00614106 |
| KIF14 | kinesin family member 14 | 0.00613718 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00613603 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00612835 |
| GPER1 | G protein-coupled estrogen receptor 1 | 0.00612657 |
| TRIM38 | tripartite motif containing 38 | 0.00611383 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00610311 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00608798 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.0060672 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00606707 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0060642 |
| LY75 | lymphocyte antigen 75 | 0.00605496 |
| FGF13 | fibroblast growth factor 13 | 0.00603116 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00601832 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00601271 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00600409 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00600293 |
| DGKA | diacylglycerol kinase, alpha 80kDa | 0.0060006 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00599861 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.00599838 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.0059982 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00598694 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00596668 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00596556 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00595926 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00595861 |
| PRSS23 | protease, serine, 23 | 0.00595472 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00594312 |
| INAVA | innate immunity activator | 0.00594236 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00594118 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00593758 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00593176 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.00592883 |
| CHRDL1 | chordin-like 1 | 0.00591132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDK1 | cyclin-dependent kinase 1 | -0.0178645 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0163315 |
| CDCA4 | cell division cycle associated 4 | -0.0150853 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0119097 |
| GAS1 | growth arrest-specific 1 | -0.0111908 |
| ZWINT | ZW10 interacting kinetochore protein | -0.0105771 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.0104933 |
| DACH1 | dachshund family transcription factor 1 | -0.00983807 |
| CCNE2 | cyclin E2 | -0.00980575 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00971372 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00951435 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00923782 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00903694 |
| EMX2 | empty spiracles homeobox 2 | -0.00899055 |
| H2AZ1 | H2A.Z variant histone 1 | -0.00874715 |
| MAP7 | microtubule-associated protein 7 | -0.00868482 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00862129 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.0084324 |
| RRM2 | ribonucleotide reductase M2 | -0.00842299 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00832983 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00832799 |
| THAP12 | THAP domain containing 12 | -0.0082941 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00824421 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00815228 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00808559 |
| RFC4 | replication factor C (activator 1) 4, 37kDa | -0.00808 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0080702 |
| FEN1 | flap structure-specific endonuclease 1 | -0.0079428 |
| COL10A1 | collagen, type X, alpha 1 | -0.00790729 |
| DICER1 | dicer 1, ribonuclease type III | -0.00785255 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.00778862 |
| USP1 | ubiquitin specific peptidase 1 | -0.00778507 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.0077124 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00767667 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.00767358 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00767058 |
| WT1 | Wilms tumor 1 | -0.0076165 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | -0.00761612 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0075987 |
| RAP2C | RAP2C, member of RAS oncogene family | -0.0075058 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00748919 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0074669 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00741821 |
| AURKB | aurora kinase B | -0.00740465 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00734761 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00733544 |
| SFN | stratifin | -0.00731916 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00730696 |
| CDC45 | cell division cycle 45 | -0.00729509 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00726296 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00718701 |
| ISOC1 | isochorismatase domain containing 1 | -0.00712001 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00710608 |
| H2AX | H2A.X variant histone | -0.00706835 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00706055 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00703875 |
| CHKB | choline kinase beta | -0.00702016 |
| TEX30 | testis expressed 30 | -0.00700909 |
| FBL | fibrillarin | -0.00699043 |
| DCHS1 | dachsous cadherin-related 1 | -0.00694337 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.0069125 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00691181 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0068612 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00685659 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | -0.00684578 |
| NUP54 | nucleoporin 54kDa | -0.00683834 |
| SLBP | stem-loop binding protein | -0.00679032 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | -0.00678644 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.0067644 |
| ESR1 | estrogen receptor 1 | -0.00674665 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0067286 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00671859 |
| TFAM | transcription factor A, mitochondrial | -0.0066802 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00667895 |
| ASPN | asporin | -0.00667047 |
| HOXC6 | homeobox C6 | -0.00666128 |
| PDLIM3 | PDZ and LIM domain 3 | -0.0066585 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00663723 |
| TRIB3 | tribbles pseudokinase 3 | -0.00663708 |
| GGCT | gamma-glutamylcyclotransferase | -0.00661321 |
| MCM3 | minichromosome maintenance complex component 3 | -0.00660212 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0065893 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00657224 |
| BCHE | butyrylcholinesterase | -0.00656794 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00655077 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00652215 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00651395 |
| PRDX2 | peroxiredoxin 2 | -0.00651117 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00650952 |
| TMPO | thymopoietin | -0.00647441 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00646439 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00645723 |
| PCNA | proliferating cell nuclear antigen | -0.00643344 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00641897 |
| EPHX3 | epoxide hydrolase 3 | -0.00641611 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00641394 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00639094 |
| TYMS | thymidylate synthetase | -0.00637124 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00635957 |
| RAD9A | RAD9 homolog A (S. pombe) | -0.00634663 |
| STK26 | serine/threonine protein kinase 26 | -0.00633689 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00633491 |
| REEP1 | receptor accessory protein 1 | -0.00632734 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00631678 |
| TRIM13 | tripartite motif containing 13 | -0.00630218 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00627543 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00627343 |
| PLXNC1 | plexin C1 | -0.00624677 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00624358 |
| ABHD17A | abhydrolase domain containing 17A | -0.00623115 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00622032 |
| TMEM126B | transmembrane protein 126B | -0.00620244 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.00619258 |
| CDC7 | cell division cycle 7 | -0.00618324 |
| IPO5 | importin 5 | -0.00616379 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0061462 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00614459 |
| NUP107 | nucleoporin 107kDa | -0.0061269 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00612319 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.00607696 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00604882 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00603223 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | -0.00600555 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00599699 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | -0.00598831 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00598277 |
| EDNRA | endothelin receptor type A | -0.00597974 |
| PFN1 | profilin 1 | -0.00596446 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -0.00596117 |
| CCNF | cyclin F | -0.00595758 |
| DCLK1 | doublecortin-like kinase 1 | -0.00594658 |
| ARGLU1 | arginine and glutamate rich 1 | -0.00594615 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00592043 |
| TPM4 | tropomyosin 4 | -0.00589045 |
| FASN | fatty acid synthase | -0.00588173 |
| RPIA | ribose 5-phosphate isomerase A | -0.00588079 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.0058617 |
| ENOPH1 | enolase-phosphatase 1 | -0.0058485 |
| S100A2 | S100 calcium binding protein A2 | -0.00583204 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -0.00581294 |
| DUT | deoxyuridine triphosphatase | -0.0058051 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00577378 |
| RPL10 | ribosomal protein L10 | -0.00574145 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00573913 |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | -0.00573871 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.00573448 |
| TARDBP | TAR DNA binding protein | -0.00572966 |
| DUSP2 | dual specificity phosphatase 2 | -0.00571836 |
| CRY1 | cryptochrome circadian clock 1 | -0.00571421 |
| HHEX | hematopoietically expressed homeobox | -0.00569488 |
| EXOSC8 | exosome component 8 | -0.00569484 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00568876 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00568003 |
| COPS4 | COP9 signalosome subunit 4 | -0.00567986 |
| PLXDC1 | plexin domain containing 1 | -0.00564387 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00564102 |
| SNAI2 | snail family zinc finger 2 | -0.00563254 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | -0.00562794 |
| PMM2 | phosphomannomutase 2 | -0.00562299 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.00562054 |
| HLTF | helicase-like transcription factor | -0.00561664 |
| NVL | nuclear VCP-like | -0.00556861 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00555886 |
| SHOX2 | short stature homeobox 2 | -0.00555501 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00555478 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00554816 |
| FBXO5 | F-box protein 5 | -0.0055279 |
| FASTKD3 | FAST kinase domains 3 | -0.00550955 |
| DGKZ | diacylglycerol kinase, zeta | -0.00549999 |
| ESD | esterase D | -0.00549859 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | -0.00548413 |
| LMNB2 | lamin B2 | -0.00547923 |
| PCLAF | PCNA clamp associated factor | -0.00547812 |
| TTI1 | TELO2 interacting protein 1 | -0.00546665 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.00546462 |
| ZNF239 | zinc finger protein 239 | -0.00546382 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00546086 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00545739 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0054416 |
| NYNRIN | NYN domain and retroviral integrase containing | -0.00543745 |
| RAF1 | Raf-1 proto-oncogene, serine/threonine kinase | -0.0054332 |
| HSPA14 | heat shock 70kDa protein 14 | -0.00542601 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00541493 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00541306 |
| TRIM28 | tripartite motif containing 28 | -0.00541154 |
| NREP | neuronal regeneration related protein | -0.00539823 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -0.0053912 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | -0.00538451 |
| HOPX | HOP homeobox | -0.00536988 |
| THAP7 | THAP domain containing 7 | -0.00536936 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.0053681 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | -0.00536492 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00536411 |
| RANBP1 | RAN binding protein 1 | -0.00535084 |
| MCMBP | minichromosome maintenance complex binding protein | -0.00533831 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00533806 |
| PRMT1 | protein arginine methyltransferase 1 | -0.0053281 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | -0.0053196 |
| DEK | DEK proto-oncogene | -0.00531482 |
| MRPL9 | mitochondrial ribosomal protein L9 | -0.00531393 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00530304 |
| EXPH5 | exophilin 5 | -0.00529345 |
| HIC2 | hypermethylated in cancer 2 | -0.00528551 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00528407 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.0052603 |
| PMF1 | polyamine-modulated factor 1 | -0.00525377 |
| MRPS12 | mitochondrial ribosomal protein S12 | -0.00525161 |
| DAZAP1 | DAZ associated protein 1 | -0.00522093 |
| SGMS1 | sphingomyelin synthase 1 | -0.00521944 |
| KLF3-AS1 | KLF3 antisense RNA 1 | -0.00521657 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00521618 |
| MCM5 | minichromosome maintenance complex component 5 | -0.00519741 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | -0.00519231 |
| TUBG1 | tubulin, gamma 1 | -0.00519155 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -0.005184 |
| PHGDH | phosphoglycerate dehydrogenase | -0.00517185 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00517028 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | -0.00516857 |
| NOL11 | nucleolar protein 11 | -0.00516782 |
| DGCR8 | DGCR8 microprocessor complex subunit | -0.00515005 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00514614 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00513527 |
| LRRC40 | leucine rich repeat containing 40 | -0.00512763 |
| ENTR1 | endosome associated trafficking regulator 1 | -0.00512731 |
| DCN | decorin | -0.00512651 |
| ATMIN | ATM interactor | -0.00511393 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | -0.00510472 |
| BRD2 | bromodomain containing 2 | -0.00509843 |
| RBBP8 | retinoblastoma binding protein 8 | -0.0050973 |
| RCAN2 | regulator of calcineurin 2 | -0.00509383 |
| GCH1 | GTP cyclohydrolase 1 | -0.00508685 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00508398 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.0050836 |
| TUBA3D | tubulin, alpha 3d | -0.00508276 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00507964 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | -0.00507858 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00507052 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | -0.00505246 |
| YEATS4 | YEATS domain containing 4 | -0.00504902 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00504442 |
| ACTL6A | actin-like 6A | -0.00503888 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00502808 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00502672 |
| TRMT5 | tRNA methyltransferase 5 | -0.00502185 |
| ANKRD49 | ankyrin repeat domain 49 | -0.00502155 |
| FRZB | frizzled-related protein | -0.00501276 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00500786 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.00500577 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00500292 |
| RTL8A | retrotransposon Gag like 8A | -0.00500287 |
