CDK11B Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cyclin-dependent kinase 11B|This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 984)
External Link http://www.ncbi.nlm.nih.gov/gene/984
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Genes

205 interacting proteins for CDK11B from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
AKAP9 A kinase (PRKA) anchor protein 9
ALMS1 Alstrom syndrome protein 1
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
AUTS2 autism susceptibility candidate 2
BCAS2 breast carcinoma amplified sequence 2
BCR breakpoint cluster region
BRD2 bromodomain containing 2
C11ORF57 chromosome 11 open reading frame 57
C18ORF25 chromosome 18 open reading frame 25
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC59 coiled-coil domain containing 59
CCND3 cyclin D3
CCNL1 cyclin L1
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CDC37 cell division cycle 37
CDC5L cell division cycle 5-like
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK4 cyclin-dependent kinase 4
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK7 cyclin-dependent kinase 7
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CENPJ centromere protein J
CEP135 centrosomal protein 135kDa
CEP152 centrosomal protein 152kDa
CEP164 centrosomal protein 164kDa
CEP192 centrosomal protein 192kDa
CEP250 centrosomal protein 250kDa
CEP290 centrosomal protein 290kDa
CEP41 centrosomal protein 41kDa
CEP57 centrosomal protein 57kDa
CEP63 centrosomal protein 63kDa
CEP70 centrosomal protein 70kDa
CEP72 centrosomal protein 72kDa
CEP76 centrosomal protein 76kDa
CEP78 centrosomal protein 78kDa
CETN2 centrin, EF-hand protein, 2
CHUK conserved helix-loop-helix ubiquitous kinase
CKAP5 cytoskeleton associated protein 5
CLASP1 cytoplasmic linker associated protein 1
CLK3 CDC-like kinase 3
CNTRL centriolin
COIL coilin
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTTN cortactin
DCAF7 DDB1 and CUL4 associated factor 7
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DDR1 discoidin domain receptor tyrosine kinase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DEK DEK proto-oncogene
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
EFCAB14 EF-hand calcium binding domain 14
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3J eukaryotic translation initiation factor 3, subunit J
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FBRS fibrosin
FBRSL1 fibrosin-like 1
FGFR1OP FGFR1 oncogene partner
GPATCH2 G patch domain containing 2
GPC4 glypican 4
GTPBP4 GTP binding protein 4
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAGHL hydroxyacylglutathione hydrolase-like
HAUS2 HAUS augmin-like complex, subunit 2
HIRIP3 HIRA interacting protein 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
KAT7 K(lysine) acetyltransferase 7
KMT2A lysine (K)-specific methyltransferase 2A
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MED1 mediator complex subunit 1
MED11 mediator complex subunit 11
MED12 mediator complex subunit 12
MED13 mediator complex subunit 13
MED13L mediator complex subunit 13-like
MED14 mediator complex subunit 14
MED15 mediator complex subunit 15
MED16 mediator complex subunit 16
MED17 mediator complex subunit 17
MED18 mediator complex subunit 18
MED19 mediator complex subunit 19
MED20 mediator complex subunit 20
MED21 mediator complex subunit 21
MED22 mediator complex subunit 22
MED23 mediator complex subunit 23
MED24 mediator complex subunit 24
MED25 mediator complex subunit 25
MED26 mediator complex subunit 26
MED28 mediator complex subunit 28
MED29 mediator complex subunit 29
MED30 mediator complex subunit 30
MED31 mediator complex subunit 31
MED4 mediator complex subunit 4
MED6 mediator complex subunit 6
MED7 mediator complex subunit 7
MED8 mediator complex subunit 8
MED9 mediator complex subunit 9
MEPCE methylphosphate capping enzyme
MSN moesin
NDE1 nudE neurodevelopment protein 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK2 NIMA-related kinase 2
NINL ninein-like
NKAP NFKB activating protein
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRP1 neuropilin 1
ODF2 outer dense fiber of sperm tails 2
OFD1 oral-facial-digital syndrome 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCGF3 polycomb group ring finger 3
PCGF5 polycomb group ring finger 5
PCM1 pericentriolar material 1
PCNT pericentrin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
PLRG1 pleiotropic regulator 1
PNKP polynucleotide kinase 3'-phosphatase
PNN pinin, desmosome associated protein
POU2F1 POU class 2 homeobox 1
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRMT1 protein arginine methyltransferase 1
PRPF19 pre-mRNA processing factor 19
PRRC2C proline-rich coiled-coil 2C
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP9 RAN binding protein 9
RAP1A RAP1A, member of RAS oncogene family
RBM25 RNA binding motif protein 25
RING1 ring finger protein 1
RNF111 ring finger protein 111
RNF2 ring finger protein 2
RNPS1 RNA binding protein S1, serine-rich domain
RPS2 ribosomal protein S2
RPS27A ribosomal protein S27a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRP1B ribosomal RNA processing 1B
RYBP RING1 and YY1 binding protein
SAP18 Sin3A-associated protein, 18kDa
SAP30BP SAP30 binding protein
SDAD1 SDA1 domain containing 1
SDC2 syndecan 2
SDCCAG8 serologically defined colon cancer antigen 8
SQSTM1 sequestosome 1
SRRM1 serine/arginine repetitive matrix 1
SSNA1 Sjogren syndrome nuclear autoantigen 1
SUMO2 small ubiquitin-like modifier 2
TCEA2 transcription elongation factor A (SII), 2
TCOF1 Treacher Collins-Franceschetti syndrome 1
TH tyrosine hydroxylase
THRAP3 thyroid hormone receptor associated protein 3
TPPP tubulin polymerization promoting protein
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TUBG1 tubulin, gamma 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
URM1 ubiquitin related modifier 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR5 WD repeat domain 5
YAF2 YY1 associated factor 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H18 zinc finger CCCH-type containing 18
ZNF687 zinc finger protein 687