CDK12 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description cyclin-dependent kinase 12| (NCBI Entrez Gene Database, 51755)
External Link https://ncbi.nlm.nih.gov/gene/51755
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Genes

500 genes differentially expressed following the CDK12 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II 0.0188235
CLU clusterin 0.0185997
KRT14 keratin 14, type I 0.0165874
IFI27 interferon, alpha-inducible protein 27 0.0157326
LTF lactotransferrin 0.0147429
STOM stomatin 0.0146403
KRT5 keratin 5, type II 0.0142971
MSX1 msh homeobox 1 0.0135174
PCNA proliferating cell nuclear antigen 0.0134222
GPX3 glutathione peroxidase 3 0.0133956
JCHAIN joining chain of multimeric IgA and IgM 0.0130625
SFRP1 secreted frizzled-related protein 1 0.0126747
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0125273
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.012377
KRT15 keratin 15, type I 0.0121141
MMP9 matrix metallopeptidase 9 0.012053
PLTP phospholipid transfer protein 0.0119944
SEPP1 selenoprotein P, plasma, 1 0.0119811
CD59 CD59 molecule, complement regulatory protein 0.0119404
LITAF lipopolysaccharide-induced TNF factor 0.0118538
SLPI secretory leukocyte peptidase inhibitor 0.0116822
CSTA cystatin A (stefin A) 0.0116219
PI3 peptidase inhibitor 3, skin-derived 0.011584
DEFB1 defensin, beta 1 0.0115005
CRYAB crystallin, alpha B 0.0114298
ELL2 elongation factor, RNA polymerase II, 2 0.0113093
TFPI2 tissue factor pathway inhibitor 2 0.0111638
CXCL12 chemokine (C-X-C motif) ligand 12 0.0109857
ARG1 arginase 1 0.0107743
COL4A5 collagen, type IV, alpha 5 0.0106601
FOXF1 forkhead box F1 0.0106323
HSPB1 heat shock 27kDa protein 1 0.0106286
ADM adrenomedullin 0.0105918
NIBAN1 niban apoptosis regulator 1 0.0104712
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.0102379
KRT23 keratin 23, type I 0.0102058
CPM carboxypeptidase M 0.0101993
HIST1H2AC histone cluster 1, H2ac 0.00988207
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00988045
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00986317
IFITM1 interferon induced transmembrane protein 1 0.00982823
MT1H metallothionein 1H 0.00977867
CLC Charcot-Leyden crystal galectin 0.00977219
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00975678
KRT6B keratin 6B, type II 0.00974752
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00969835
POU2AF1 POU class 2 associating factor 1 0.00967404
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00963195
KRT17 keratin 17, type I 0.00957731
RAB13 RAB13, member RAS oncogene family 0.00956426
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00954005
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00947749
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00946275
PRDX2 peroxiredoxin 2 0.00944721
HSPA1A heat shock 70kDa protein 1A 0.00944219
HSPB8 heat shock 22kDa protein 8 0.00938131
EXT1 exostosin glycosyltransferase 1 0.00929205
KRT16 keratin 16, type I 0.00927875
PEG10 paternally expressed 10 0.00926542
CD52 CD52 molecule 0.00925114
OLFM4 olfactomedin 4 0.00923393
IL1RN interleukin 1 receptor antagonist 0.00922428
GRN granulin 0.00920295
SORBS3 sorbin and SH3 domain containing 3 0.00920029
S100A9 S100 calcium binding protein A9 0.00918954
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00911297
MIR22HG MIR22 host gene 0.00906093
CCL19 chemokine (C-C motif) ligand 19 0.00904007
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00895836
MT1HL1 metallothionein 1H-like 1 0.0089414
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00890832
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00890572
MT1E metallothionein 1E 0.00888641
PERP PERP, TP53 apoptosis effector 0.00886605
SPRR1B small proline-rich protein 1B 0.00879336
MT1F metallothionein 1F 0.00878452
PSAP prosaposin 0.00878427
KRT6A keratin 6A, type II 0.00875031
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00874363
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00872033
ZNHIT1 zinc finger, HIT-type containing 1 0.00871027
PTGES prostaglandin E synthase 0.00867878
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0086196
RTN2 reticulon 2 0.00857313
PLIN1 perilipin 1 0.00854815
CD36 CD36 molecule (thrombospondin receptor) 0.00854801
TUBA4A tubulin, alpha 4a 0.00852893
CNTN1 contactin 1 0.00852139
ATF3 activating transcription factor 3 0.00851528
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.0084966
AQP3 aquaporin 3 (Gill blood group) 0.00849119
ZNF395 zinc finger protein 395 0.00847672
SDC4 syndecan 4 0.00844969
DEFA4 defensin, alpha 4, corticostatin 0.00841276
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00841186
MVP major vault protein 0.00837795
MGLL monoglyceride lipase 0.00835142
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.0083407
SPRR1A small proline-rich protein 1A 0.00833572
DSP desmoplakin 0.00833224
TACSTD2 tumor-associated calcium signal transducer 2 0.00832535
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00831696
MT1X metallothionein 1X 0.00827541
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00826264
C1S complement component 1, s subcomponent 0.00825493
MT2A metallothionein 2A 0.00821748
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00817551
BMP2 bone morphogenetic protein 2 0.00815279
MT1G metallothionein 1G 0.00812504
MXI1 MAX interactor 1, dimerization protein 0.00810504
CRCT1 cysteine-rich C-terminal 1 0.00800394
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00797118
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00788534
ADAMDEC1 ADAM-like, decysin 1 0.00787278
CXCL14 chemokine (C-X-C motif) ligand 14 0.00786741
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00785139
SGK1 serum/glucocorticoid regulated kinase 1 0.00784155
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00782349
TBX3 T-box 3 0.00781175
TXNIP thioredoxin interacting protein 0.0077801
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00777698
ANXA3 annexin A3 0.0077252
FOXC1 forkhead box C1 0.0077158
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.0077079
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 0.00769194
RBPMS RNA binding protein with multiple splicing 0.00765296
SOWAHC sosondowah ankyrin repeat domain family member C 0.00758796
G0S2 G0/G1 switch 2 0.00758291
SCGB2A2 secretoglobin, family 2A, member 2 0.00755824
SOX9 SRY (sex determining region Y)-box 9 0.0075576
FKBP11 FK506 binding protein 11, 19 kDa 0.00755703
DDIT3 DNA-damage-inducible transcript 3 0.00752852
GSTK1 glutathione S-transferase kappa 1 0.00751447
DUSP5 dual specificity phosphatase 5 0.00749506
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00747608
STC2 stanniocalcin 2 0.00746653
PITX1 paired-like homeodomain 1 0.0074641
IL7R interleukin 7 receptor 0.0074373
HIST1H2BD histone cluster 1, H2bd 0.00739864
CDC42 cell division cycle 42 0.00739306
TUFT1 tuftelin 1 0.00729662
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.00729594
GZMK granzyme K (granzyme 3; tryptase II) 0.00727844
CXCL13 chemokine (C-X-C motif) ligand 13 0.00724395
SDC2 syndecan 2 0.00720594
FCGBP Fc fragment of IgG binding protein 0.00720298
CD14 CD14 molecule 0.00720292
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00720173
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00717913
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00717818
LYPD3 LY6/PLAUR domain containing 3 0.00716518
GM2A GM2 ganglioside activator 0.00714552
SALL1 spalt-like transcription factor 1 0.00713183
MITF microphthalmia-associated transcription factor 0.00712147
CES1 carboxylesterase 1 0.00711805
STK17A serine/threonine kinase 17a 0.00711095
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00706635
AHNAK AHNAK nucleoprotein 0.00705844
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00705322
AVPI1 arginine vasopressin-induced 1 0.00704195
CLCA2 chloride channel accessory 2 0.00703909
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00703461
ACTN1 actinin, alpha 1 0.00703438
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00700486
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0069983
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00696774
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0069197
UROD uroporphyrinogen decarboxylase 0.00691765
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00691141
FSTL1 follistatin-like 1 0.00690815
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00690101
BHMT2 betaine--homocysteine S-methyltransferase 2 0.00688877
S100A11 S100 calcium binding protein A11 0.00688831
TMEM45A transmembrane protein 45A 0.00687851
S100A7 S100 calcium binding protein A7 0.0068736
NFIL3 nuclear factor, interleukin 3 regulated 0.0068596
ZMYND8 zinc finger, MYND-type containing 8 0.00683672
TMEM140 transmembrane protein 140 0.00683258
ATP5MF ATP synthase membrane subunit f 0.00680526
CTSG cathepsin G 0.00679576
RND3 Rho family GTPase 3 0.00679398
CDA cytidine deaminase 0.00678542
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00677828
RELN reelin 0.00676774
CA12 carbonic anhydrase XII 0.00675178
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00673709
CLCA4 chloride channel accessory 4 0.00673454
GRAMD2B GRAM domain containing 2B 0.00672779
FAM46C family with sequence similarity 46, member C 0.00669033
NPC1 Niemann-Pick disease, type C1 0.00668146
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00667654
TMEM59 transmembrane protein 59 0.00667068
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00664703
PURA purine-rich element binding protein A 0.0066449
LIMA1 LIM domain and actin binding 1 0.00663852
SPRR2B small proline-rich protein 2B 0.00659043
PGF placental growth factor 0.00655626
BPGM 2,3-bisphosphoglycerate mutase 0.00654515
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00653466
F3 coagulation factor III (thromboplastin, tissue factor) 0.00646785
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.0064662
CLTB clathrin, light chain B 0.00644517
MAP3K7CL MAP3K7 C-terminal like 0.00644113
S100A8 S100 calcium binding protein A8 0.0064385
BAG3 BCL2-associated athanogene 3 0.00642253
IFI6 interferon, alpha-inducible protein 6 0.00641013
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0063948
EMC3 ER membrane protein complex subunit 3 0.00638341
NDEL1 nudE neurodevelopment protein 1-like 1 0.00637953
CYTL1 cytokine-like 1 0.00637742
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00636491
NCOA4 nuclear receptor coactivator 4 0.0063605
SOD2 superoxide dismutase 2, mitochondrial 0.00635702
MPO myeloperoxidase 0.00635027
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 0.0063311
RRAGC Ras-related GTP binding C 0.00631503
CREM cAMP responsive element modulator 0.00631325
OGA O-GlcNAcase 0.00630299
JUND jun D proto-oncogene 0.00630276
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.00629782
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00628608
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00628568
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.00628309
FABP4 fatty acid binding protein 4, adipocyte 0.00627996
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00627752
CD63 CD63 molecule 0.00627161
HECA headcase homolog (Drosophila) 0.00626536
XIC X chromosome inactivation center 0.00625949
GSTT1 glutathione S-transferase theta 1 0.00625703
MYO6 myosin VI 0.00624056
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00623878
EZR ezrin 0.00621492
IVNS1ABP influenza virus NS1A binding protein 0.00618816
CALML3 calmodulin-like 3 0.00615353
SERF2 small EDRK-rich factor 2 0.00615313
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00614713
PLAUR plasminogen activator, urokinase receptor 0.00614375
KLF6 Kruppel-like factor 6 0.00613734
HBP1 HMG-box transcription factor 1 0.00611976
TFG TRK-fused gene 0.00609722
EGR1 early growth response 1 0.00609618
PEBP1 phosphatidylethanolamine binding protein 1 0.00609072
ACKR3 atypical chemokine receptor 3 0.00609022
ABHD4 abhydrolase domain containing 4 0.0060848
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00606188
ZNF394 zinc finger protein 394 0.00605222
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.0060439
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00600843
MAL mal, T-cell differentiation protein 0.00599807
AHNAK2 AHNAK nucleoprotein 2 0.0059964

decreased expression

Symbol Name Standardized Value
BGN biglycan -0.0160017
WT1 Wilms tumor 1 -0.0155942
TBC1D31 TBC1 domain family, member 31 -0.0153674
PLN phospholamban -0.0147921
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.013371
SFRP4 secreted frizzled-related protein 4 -0.0130948
DPYSL3 dihydropyrimidinase-like 3 -0.0127553
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0126361
PCP4 Purkinje cell protein 4 -0.0124385
ZFPM2 zinc finger protein, FOG family member 2 -0.0122383
C3ORF14 chromosome 3 open reading frame 14 -0.0122365
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0120246
COL10A1 collagen, type X, alpha 1 -0.0118809
ALCAM activated leukocyte cell adhesion molecule -0.0118605
TXNDC9 thioredoxin domain containing 9 -0.0117682
CCN2 cellular communication network factor 2 -0.0117209
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0115883
TSPAN7 tetraspanin 7 -0.0113357
MYH11 myosin, heavy chain 11, smooth muscle -0.0113291
PTGIS prostaglandin I2 (prostacyclin) synthase -0.0113
COL11A1 collagen, type XI, alpha 1 -0.0112264
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.0111052
FBXO21 F-box protein 21 -0.0108898
ASPN asporin -0.0102038
NDNF neuron-derived neurotrophic factor -0.0101683
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0100703
MYO5C myosin VC -0.0100561
WDR61 WD repeat domain 61 -0.00996518
AKR1C3 aldo-keto reductase family 1, member C3 -0.00987907
GAS1 growth arrest-specific 1 -0.00974075
AEBP1 AE binding protein 1 -0.00973406
COMP cartilage oligomeric matrix protein -0.0096252
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.0095744
SULF1 sulfatase 1 -0.00950641
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00948173
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00932089
POSTN periostin, osteoblast specific factor -0.0092912
RAB15 RAB15, member RAS oncogene family -0.00927633
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00916322
NEBL nebulette -0.0091531
CD200 CD200 molecule -0.00908432
MSLN mesothelin -0.00907131
TSPAN8 tetraspanin 8 -0.00906406
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00888302
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.0086896
GSTA4 glutathione S-transferase alpha 4 -0.00868545
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00855786
HMGB3 high mobility group box 3 -0.00854103
CDC45 cell division cycle 45 -0.0085255
TRIP13 thyroid hormone receptor interactor 13 -0.00850697
CADM1 cell adhesion molecule 1 -0.00845335
FBP1 fructose-1,6-bisphosphatase 1 -0.00844566
C9ORF3 chromosome 9 open reading frame 3 -0.00838087
LTBP2 latent transforming growth factor beta binding protein 2 -0.00832424
MGP matrix Gla protein -0.00832379
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00831559
PLS3 plastin 3 -0.00827376
CD38 CD38 molecule -0.00827359
TAGLN transgelin -0.00810943
ABHD2 abhydrolase domain containing 2 -0.0080569
THY1 Thy-1 cell surface antigen -0.00801331
CADPS2 Ca++-dependent secretion activator 2 -0.00800351
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00797122
PRIM1 primase, DNA, polypeptide 1 (49kDa) -0.00793802
C11ORF71 chromosome 11 open reading frame 71 -0.00792717
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00791956
RHOBTB3 Rho-related BTB domain containing 3 -0.00787057
ZW10 zw10 kinetochore protein -0.00786577
CLIC5 chloride intracellular channel 5 -0.0078408
CEMIP cell migration inducing protein, hyaluronan binding -0.00782628
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00781236
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00780917
ENOPH1 enolase-phosphatase 1 -0.00777012
SMYD3 SET and MYND domain containing 3 -0.00773666
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.00773481
CDC7 cell division cycle 7 -0.0077329
MACF1 microtubule-actin crosslinking factor 1 -0.00763351
ATP10B ATPase, class V, type 10B -0.00762583
ADGRF5 adhesion G protein-coupled receptor F5 -0.00759735
FZD6 frizzled class receptor 6 -0.00759393
TARDBP TAR DNA binding protein -0.0075889
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00755779
FRY furry homolog (Drosophila) -0.00753131
EMX2 empty spiracles homeobox 2 -0.00752431
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.00751218
QPCT glutaminyl-peptide cyclotransferase -0.00748458
CEP55 centrosomal protein 55kDa -0.00747519
DSCC1 DNA replication and sister chromatid cohesion 1 -0.0074504
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00742978
TRIB2 tribbles pseudokinase 2 -0.00738293
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.0073726
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00736907
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -0.0073661
PDLIM3 PDZ and LIM domain 3 -0.00733862
LMNB2 lamin B2 -0.00732971
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00732164
TSPYL5 TSPY-like 5 -0.00731409
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00728889
LACTB2 lactamase, beta 2 -0.00724658
TMSB15A thymosin beta 15a -0.00724294
MEF2C myocyte enhancer factor 2C -0.0072351
RXYLT1 ribitol xylosyltransferase 1 -0.00723218
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00721253
STK26 serine/threonine protein kinase 26 -0.00721068
TDO2 tryptophan 2,3-dioxygenase -0.00720102
HOXC6 homeobox C6 -0.00719097
TBX2 T-box 2 -0.00715113
SPON1 spondin 1, extracellular matrix protein -0.00713302
SLC2A4RG SLC2A4 regulator -0.00710173
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -0.00709837
ATAD2 ATPase family, AAA domain containing 2 -0.00708284
CALB1 calbindin 1, 28kDa -0.00708119
PRMT3 protein arginine methyltransferase 3 -0.00705344
MICU2 mitochondrial calcium uptake 2 -0.00702804
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00699244
HEPH hephaestin -0.00698982
LY86 lymphocyte antigen 86 -0.00697979
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00695833
NKX2-1 NK2 homeobox 1 -0.00695791
C2CD5 C2 calcium-dependent domain containing 5 -0.00695624
GPX2 glutathione peroxidase 2 -0.00694239
FABP6 fatty acid binding protein 6, ileal -0.00691416
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00688008
CEL carboxyl ester lipase -0.00685294
GATA6 GATA binding protein 6 -0.00683778
BPIFA1 BPI fold containing family A, member 1 -0.00683194
DOK5 docking protein 5 -0.00681356
FGG fibrinogen gamma chain -0.00680995
CCR2 chemokine (C-C motif) receptor 2 -0.00676484
SLC38A1 solute carrier family 38, member 1 -0.00675351
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00674809
FAR2 fatty acyl CoA reductase 2 -0.00671706
TOX3 TOX high mobility group box family member 3 -0.00670725
GLB1L2 galactosidase, beta 1-like 2 -0.00670409
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00666188
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00665127
GGCT gamma-glutamylcyclotransferase -0.00664499
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00661805
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.0065986
RGCC regulator of cell cycle -0.00659094
AGR2 anterior gradient 2 -0.00658251
SYT1 synaptotagmin I -0.00657426
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00657333
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00656834
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00651197
SFTPB surfactant protein B -0.00649039
RNF43 ring finger protein 43 -0.00648691
PDGFRL platelet-derived growth factor receptor-like -0.0064794
RADX RPA1 related single stranded DNA binding protein, X-linked -0.00647186
TEAD4 TEA domain family member 4 -0.00644516
PIMREG PICALM interacting mitotic regulator -0.00643686
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00642076
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00638924
FAM3C family with sequence similarity 3, member C -0.00638598
CDKN3 cyclin-dependent kinase inhibitor 3 -0.006385
TNNC1 troponin C type 1 (slow) -0.00636053
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00635255
SQLE squalene epoxidase -0.00633528
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00633052
SMAD3 SMAD family member 3 -0.00632977
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00631842
OIP5 Opa interacting protein 5 -0.00631784
ECT2 epithelial cell transforming 2 -0.00630916
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.00629624
UGT8 UDP glycosyltransferase 8 -0.00627828
CD93 CD93 molecule -0.00627758
MAPK9 mitogen-activated protein kinase 9 -0.00626789
EMP2 epithelial membrane protein 2 -0.00625077
CKAP2 cytoskeleton associated protein 2 -0.00623424
RNF144A ring finger protein 144A -0.00622805
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.006222
DPEP1 dipeptidase 1 (renal) -0.00621203
ST18 suppression of tumorigenicity 18, zinc finger -0.00620275
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00619896
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00618932
ANOS1 anosmin 1 -0.00618438
LRRC8B leucine rich repeat containing 8 family, member B -0.00617954
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00617384
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00616565
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.00615678
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00615469
XYLT1 xylosyltransferase I -0.00614826
CCP110 centriolar coiled coil protein 110kDa -0.00614338
KDM5D lysine (K)-specific demethylase 5D -0.00614327
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00613916
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00613598
EPYC epiphycan -0.00612285
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00611991
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00609984
PBX1 pre-B-cell leukemia homeobox 1 -0.00609741
SFTPC surfactant protein C -0.00608376
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00607272
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -0.00607269
EAF2 ELL associated factor 2 -0.00606055
CALCA calcitonin-related polypeptide alpha -0.00604703
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00604609
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00604025
EMC9 ER membrane protein complex subunit 9 -0.00603346
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -0.00603241
ADGRG2 adhesion G protein-coupled receptor G2 -0.00602444
SLF2 SMC5-SMC6 complex localization factor 2 -0.00602057
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00601654
PDE10A phosphodiesterase 10A -0.00599327
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00599157
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00598818
FLI1 Fli-1 proto-oncogene, ETS transcription factor -0.00598006
ACYP1 acylphosphatase 1, erythrocyte (common) type -0.00596598
ZFAND1 zinc finger, AN1-type domain 1 -0.00595408
ABHD11 abhydrolase domain containing 11 -0.00594185
LRRC15 leucine rich repeat containing 15 -0.00593912
PRUNE2 prune homolog 2 (Drosophila) -0.00592203
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.00591953
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.00591315
CCNB1 cyclin B1 -0.00591184
TCTA T-cell leukemia translocation altered -0.00590082
ACAD8 acyl-CoA dehydrogenase family, member 8 -0.00590028
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00589952
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00588851
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00588731
TPSAB1 tryptase alpha/beta 1 -0.00588293
PDGFC platelet derived growth factor C -0.0058784
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00587786
OGN osteoglycin -0.00585304
TTC19 tetratricopeptide repeat domain 19 -0.00581135
LIPT1 lipoyltransferase 1 -0.00580864
NEK2 NIMA-related kinase 2 -0.00578292
APIP APAF1 interacting protein -0.0057738
ANKRD36 ankyrin repeat domain 36 -0.00576158
DGKD diacylglycerol kinase, delta 130kDa -0.00573743
ESD esterase D -0.00572953
DPYSL2 dihydropyrimidinase-like 2 -0.00572893
RAD51AP1 RAD51 associated protein 1 -0.00572375
NGLY1 N-glycanase 1 -0.00572318
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00571867
CIT citron rho-interacting serine/threonine kinase -0.0057045
OXA1L oxidase (cytochrome c) assembly 1-like -0.00569407
MB myoglobin -0.00569383
NIT1 nitrilase 1 -0.0056901
MACROD1 MACRO domain containing 1 -0.00567624
RMI1 RecQ mediated genome instability 1 -0.00566544
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00566057
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00565088
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.00564943
CPE carboxypeptidase E -0.00564145
JCAD junctional cadherin 5 associated -0.00564101
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.00563274
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.00563165
WISP1 WNT1 inducible signaling pathway protein 1 -0.00561363
CYC1 cytochrome c-1 -0.00561361
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.00560863