CDK19 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cyclin-dependent kinase 19|This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 23097)
External Link http://www.ncbi.nlm.nih.gov/gene/23097
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Genes

370 interacting proteins for CDK19 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
AFG3L2 AFG3-like AAA ATPase 2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AGPS alkylglycerone phosphate synthase
AHCTF1 AT hook containing transcription factor 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANAPC1 anaphase promoting complex subunit 1
ANAPC2 anaphase promoting complex subunit 2
ANAPC5 anaphase promoting complex subunit 5
APMAP adipocyte plasma membrane associated protein
APOD apolipoprotein D
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARL8B ADP-ribosylation factor-like 8B
ATAD3A ATPase family, AAA domain containing 3A
ATAD3B ATPase family, AAA domain containing 3B
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATR ATR serine/threonine kinase
AUP1 ancient ubiquitous protein 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT1
BAG2 BCL2-associated athanogene 2
BCAP31 B-cell receptor-associated protein 31
BCL6 B-cell CLL/lymphoma 6
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CANX calnexin
CAPRIN1 cell cycle associated protein 1
CCAR1 cell division cycle and apoptosis regulator 1
CCNC cyclin C
CCNT1 cyclin T1
CCNT2 cyclin T2
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDC23 cell division cycle 23
CDK7 cyclin-dependent kinase 7
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CERS1 ceramide synthase 1
CHD9 chromodomain helicase DNA binding protein 9
CLCC1 chloride channel CLIC-like 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLU clusterin
CMSS1 cms1 ribosomal small subunit homolog (yeast)
COMMD4 COMM domain containing 4
COMT catechol-O-methyltransferase
COPA coatomer protein complex, subunit alpha
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTCF CCCTC-binding factor (zinc finger protein)
CUTA cutA divalent cation tolerance homolog (E. coli)
CYB5R3 cytochrome b5 reductase 3
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DCD dermcidin
DDB1 damage-specific DNA binding protein 1, 127kDa
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DHCR7 7-dehydrocholesterol reductase
DHRS7 dehydrogenase/reductase (SDR family) member 7
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DICER1 dicer 1, ribonuclease type III
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNALI1 dynein, axonemal, light intermediate chain 1
DNM2 dynamin 2
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EAF1 ELL associated factor 1
EAF2 ELL associated factor 2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF4A1 eukaryotic translation initiation factor 4A1
ELL elongation factor RNA polymerase II
ELL2 elongation factor, RNA polymerase II, 2
ELL3 elongation factor RNA polymerase II-like 3
EMD emerin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERC1 ELKS/RAB6-interacting/CAST family member 1
ESYT1 extended synaptotagmin-like protein 1
ESYT2 extended synaptotagmin-like protein 2
EXOC4 exocyst complex component 4
FAF2 Fas associated factor family member 2
FANCD2 Fanconi anemia, complementation group D2
FAR1 fatty acyl CoA reductase 1
FBL fibrillarin
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FKBP15 FK506 binding protein 15, 133kDa
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GLUD1 glutamate dehydrogenase 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNPAT glyceronephosphate O-acyltransferase
GOLGA2 golgin A2
GPN1 GPN-loop GTPase 1
GPN3 GPN-loop GTPase 3
HACD3 3-hydroxyacyl-CoA dehydratase 3
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HAUS7 HAUS augmin-like complex, subunit 7
HAX1 HCLS1 associated protein X-1
HCFC1 host cell factor C1
HDAC6 histone deacetylase 6
HEATR1 HEAT repeat containing 1
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HLA-C major histocompatibility complex, class I, C
HM13 histocompatibility (minor) 13
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IPO4 importin 4
IPO7 importin 7
IPO8 importin 8
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA1524 KIAA1524
KLHDC2 kelch domain containing 2
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA4 karyopherin alpha 4 (importin alpha 3)
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LMAN2 lectin, mannose-binding 2
LMBR1 limb development membrane protein 1
LMNA lamin A/C
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC59 leucine rich repeat containing 59
LUC7L3 LUC7-like 3 (S. cerevisiae)
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MDN1 MDN1, midasin homolog (yeast)
MED1 mediator complex subunit 1
MED10 mediator complex subunit 10
MED11 mediator complex subunit 11
MED12 mediator complex subunit 12
MED13 mediator complex subunit 13
MED13L mediator complex subunit 13-like
MED14 mediator complex subunit 14
MED15 mediator complex subunit 15
MED16 mediator complex subunit 16
MED17 mediator complex subunit 17
MED18 mediator complex subunit 18
MED19 mediator complex subunit 19
MED20 mediator complex subunit 20
MED21 mediator complex subunit 21
MED22 mediator complex subunit 22
MED23 mediator complex subunit 23
MED24 mediator complex subunit 24
MED25 mediator complex subunit 25
MED26 mediator complex subunit 26
MED27 mediator complex subunit 27
MED28 mediator complex subunit 28
MED29 mediator complex subunit 29
MED30 mediator complex subunit 30
MED31 mediator complex subunit 31
MED4 mediator complex subunit 4
MED6 mediator complex subunit 6
MED7 mediator complex subunit 7
MED8 mediator complex subunit 8
MED9 mediator complex subunit 9
MOGS mannosyl-oligosaccharide glucosidase
MON2 MON2 homolog (S. cerevisiae)
MSH6 mutS homolog 6
MTDH metadherin
MTX1 metaxin 1
MYBBP1A MYB binding protein (P160) 1a
MYCBPAP MYCBP associated protein
MYEF2 myelin expression factor 2
NCLN nicalin
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLRX1 NLR family member X1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOL8 nucleolar protein 8
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOMO1 NODAL modulator 1
NONO non-POU domain containing, octamer-binding
NOP56 NOP56 ribonucleoprotein
NOP58 NOP58 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRF1 nuclear respiratory factor 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUMA1 nuclear mitotic apparatus protein 1
NUP205 nucleoporin 205kDa
NUP210 nucleoporin 210kDa
NUP93 nucleoporin 93kDa
OSBPL8 oxysterol binding protein-like 8
P3H1 prolyl 3-hydroxylase 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PGAM5 phosphoglycerate mutase family member 5
PGRMC1 progesterone receptor membrane component 1
PGRMC2 progesterone receptor membrane component 2
PHGDH phosphoglycerate dehydrogenase
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP prolactin-induced protein
PNN pinin, desmosome associated protein
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPP6C protein phosphatase 6, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF19 pre-mRNA processing factor 19
PRPF4B pre-mRNA processing factor 4B
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PTBP1 polypyrimidine tract binding protein 1
PTGES2 prostaglandin E synthase 2
PTOV1 prostate tumor overexpressed 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RAB11A RAB11A, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RAI14 retinoic acid induced 14
RANGAP1 Ran GTPase activating protein 1
RB1CC1 RB1-inducible coiled-coil 1
RBM39 RNA binding motif protein 39
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RECQL5 RecQ protein-like 5
RFC3 replication factor C (activator 1) 3, 38kDa
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RNPS1 RNA binding protein S1, serine-rich domain
RPAP2 RNA polymerase II associated protein 2
RPL14 ribosomal protein L14
RPL3 ribosomal protein L3
RPN1 ribophorin I
RSL1D1 ribosomal L1 domain containing 1
RTN4 reticulon 4
RUVBL1 RuvB-like AAA ATPase 1
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCAMP3 secretory carrier membrane protein 3
SCCPDH saccharopine dehydrogenase (putative)
SCFD1 sec1 family domain containing 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SMN2 survival of motor neuron 2, centromeric
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SPAG5 sperm associated antigen 5
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRP68 signal recognition particle 68kDa
SRP72 signal recognition particle 72kDa
SRPRB signal recognition particle receptor, B subunit
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TARDBP TAR DNA binding protein
TBC1D15 TBC1 domain family, member 15
TBCD tubulin folding cofactor D
TBP TATA box binding protein
TCOF1 Treacher Collins-Franceschetti syndrome 1
TFRC transferrin receptor
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM9SF4 transmembrane 9 superfamily protein member 4
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM161A transmembrane protein 161A
TMLHE trimethyllysine hydroxylase, epsilon
TMPO thymopoietin
TMX1 thioredoxin-related transmembrane protein 1
TNPO1 transportin 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOR1AIP1 torsin A interacting protein 1
TRAFD1 TRAF-type zinc finger domain containing 1
TRAP1 TNF receptor-associated protein 1
TRIM28 tripartite motif containing 28
TRIP13 thyroid hormone receptor interactor 13
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TTI1 TELO2 interacting protein 1
TTN titin
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBB4B tubulin, beta 4B class IVb
TUFM Tu translation elongation factor, mitochondrial
U2SURP U2 snRNP-associated SURP domain containing
UBB ubiquitin B
UBE3C ubiquitin protein ligase E3C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBTF upstream binding transcription factor, RNA polymerase I
UNC45A unc-45 homolog A (C. elegans)
VAC14 Vac14 homolog (S. cerevisiae)
VAT1 vesicle amine transport 1
VCP valosin containing protein
WRNIP1 Werner helicase interacting protein 1
XPO1 exportin 1
XPO5 exportin 5
YME1L1 YME1-like 1 ATPase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB9 zinc finger and BTB domain containing 9
ZC3H13 zinc finger CCCH-type containing 13
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF281 zinc finger protein 281