CDK19_knockdown_164_GSE38061 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38061
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Genes

600 genes differentially expressed following the CDK19_knockdown_164_GSE38061 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
EHF ets homologous factor 4.12167
FAM3C family with sequence similarity 3, member C 3.95357
PROM1 prominin 1 3.93392
HOXB8 homeobox B8 3.65508
CD44 CD44 molecule (Indian blood group) 3.6465
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 3.52909
MFSD3 major facilitator superfamily domain containing 3 3.29957
RPL36 ribosomal protein L36 3.28097
RAB25 RAB25, member RAS oncogene family 3.27976
CRTAP cartilage associated protein 3.24906
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 3.17084
KLK10 kallikrein-related peptidase 10 3.13324
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 3.11846
DBP D site of albumin promoter (albumin D-box) binding protein 3.08631
TRIP6 thyroid hormone receptor interactor 6 3.08363
EHBP1 EH domain binding protein 1 3.06221
TNS4 tensin 4 3.03083
NR2F1 nuclear receptor subfamily 2, group F, member 1 2.96624
ARF6 ADP-ribosylation factor 6 2.95319
SECTM1 secreted and transmembrane 1 2.93164
SUSD2 sushi domain containing 2 2.91193
PHLDB2 pleckstrin homology-like domain, family B, member 2 2.899
ZBTB14 zinc finger and BTB domain containing 14 2.8693
AKAP8L A kinase (PRKA) anchor protein 8-like 2.84214
ABHD11 abhydrolase domain containing 11 2.7976
AKAP1 A kinase (PRKA) anchor protein 1 2.67891
ANO1 anoctamin 1, calcium activated chloride channel 2.66901
CNTNAP3 contactin associated protein-like 3 2.66319
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 2.57949
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.57913
DDIT4L DNA-damage-inducible transcript 4-like 2.50166
DCLK1 doublecortin-like kinase 1 2.48323
DGAT1 diacylglycerol O-acyltransferase 1 2.46617
MET MET proto-oncogene, receptor tyrosine kinase 2.45196
DPYSL2 dihydropyrimidinase-like 2 2.44769
EWSAT1 Ewing sarcoma associated transcript 1 2.41852
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.40105
GALK1 galactokinase 1 2.38787
TYMS thymidylate synthetase 2.38104
SNX17 sorting nexin 17 2.36856
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.36444
RXFP4 relaxin/insulin-like family peptide receptor 4 2.34335
ADGRF1 adhesion G protein-coupled receptor F1 2.33735
TTC19 tetratricopeptide repeat domain 19 2.33181
EVA1C eva-1 homolog C (C. elegans) 2.33129
RFC2 replication factor C (activator 1) 2, 40kDa 2.32796
IL17RD interleukin 17 receptor D 2.31429
KLK7 kallikrein-related peptidase 7 2.30332
GBP4 guanylate binding protein 4 2.30225
MCMBP minichromosome maintenance complex binding protein 2.29867
KLK6 kallikrein-related peptidase 6 2.28555
MBNL3 muscleblind-like splicing regulator 3 2.25889
SNX5 sorting nexin 5 2.25763
MRPL33 mitochondrial ribosomal protein L33 2.25585
FLOT1 flotillin 1 2.22769
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.22286
UBE2E2 ubiquitin-conjugating enzyme E2E 2 2.2186
CDC123 cell division cycle 123 2.2153
GCAT glycine C-acetyltransferase 2.21305
PLCD3 phospholipase C, delta 3 2.1771
TSPAN4 tetraspanin 4 2.17601
TINAGL1 tubulointerstitial nephritis antigen-like 1 2.17453
YBX1 Y box binding protein 1 2.17334
MAML2 mastermind-like 2 (Drosophila) 2.16221
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 2.15895
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 2.154
TGM2 transglutaminase 2 2.14482
NF2 neurofibromin 2 (merlin) 2.14054
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.13351
ETV5 ets variant 5 2.12226
ATXN10 ataxin 10 2.11809
LIX1L Lix1 homolog (chicken) like 2.11487
PITRM1 pitrilysin metallopeptidase 1 2.07522
ITGB4 integrin, beta 4 2.0703
EEF2K eukaryotic elongation factor 2 kinase 2.06836
ISYNA1 inositol-3-phosphate synthase 1 2.0629
RAB3A RAB3A, member RAS oncogene family 2.03518
PARK7 parkinson protein 7 2.03485
DAP death-associated protein 2.03369
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.032
RUNX3 runt-related transcription factor 3 2.00426
ADGRG6 adhesion G protein-coupled receptor G6 1.99732
GNG12 guanine nucleotide binding protein (G protein), gamma 12 1.99732
TRA2B transformer 2 beta homolog (Drosophila) 1.99201
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 1.9889
EMP1 epithelial membrane protein 1 1.97944
ZNF704 zinc finger protein 704 1.96924
C7ORF50 chromosome 7 open reading frame 50 1.95681
MORC4 MORC family CW-type zinc finger 4 1.94762
RPS2 ribosomal protein S2 1.94419
PRKCQ protein kinase C, theta 1.94345
HNF4A hepatocyte nuclear factor 4, alpha 1.93731
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.90405
BMP4 bone morphogenetic protein 4 1.88453
RAN RAN, member RAS oncogene family 1.87656
TRIM61 tripartite motif containing 61 1.86431
HOXB9 homeobox B9 1.85629
LCN2 lipocalin 2 1.85318
SPRED2 sprouty-related, EVH1 domain containing 2 1.83131
SLC16A6 solute carrier family 16, member 6 1.81785
GM2A GM2 ganglioside activator 1.81207
ACTN4 actinin, alpha 4 1.80326
ANKRD39 ankyrin repeat domain 39 1.79221
ZNF358 zinc finger protein 358 1.79155
CAT catalase 1.79008
SLC30A3 solute carrier family 30 (zinc transporter), member 3 1.77967
TNS2 tensin 2 1.77895
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 1.77556
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.7635
TGFB2 transforming growth factor, beta 2 1.7584
UCK2 uridine-cytidine kinase 2 1.7494
TMEM263 transmembrane protein 263 1.74777
DPY30 dpy-30 homolog (C. elegans) 1.74457
FAR2 fatty acyl CoA reductase 2 1.74429
ADGRG1 adhesion G protein-coupled receptor G1 1.74376
RPS6 ribosomal protein S6 1.72642
DCXR dicarbonyl/L-xylulose reductase 1.71753
BID BH3 interacting domain death agonist 1.71063
TMEM173 transmembrane protein 173 1.70625
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.6962
OTX1 orthodenticle homeobox 1 1.69436
TMEM45B transmembrane protein 45B 1.69201
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.68302
NPTXR neuronal pentraxin receptor 1.68289
SRPR signal recognition particle receptor (docking protein) 1.68152
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.68123
CDK4 cyclin-dependent kinase 4 1.68105
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.67314
SUMO3 small ubiquitin-like modifier 3 1.67024
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 1.66424
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1.66137
TESC tescalcin 1.65556
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.64859
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.64778
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.64345
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 1.6427
RNASEH2A ribonuclease H2, subunit A 1.64166
STXBP6 syntaxin binding protein 6 (amisyn) 1.63046
LHX6 LIM homeobox 6 1.62408
ATRAID all-trans retinoic acid-induced differentiation factor 1.60358
VSNL1 visinin-like 1 1.60017
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 1.59536
SAV1 salvador family WW domain containing protein 1 1.59495
WDR4 WD repeat domain 4 1.59472
PVRL3 poliovirus receptor-related 3 1.59062
CCNG1 cyclin G1 1.58675
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.58098
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.57995
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 1.57832
JAG1 jagged 1 1.57801
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.57103
SEPT3 septin 3 1.56849
RHOU ras homolog family member U 1.56653
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.56328
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 1.56187
ACOT7 acyl-CoA thioesterase 7 1.55872
EPHX3 epoxide hydrolase 3 1.55662
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.54775
GLB1L2 galactosidase, beta 1-like 2 1.54771
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.54419
ZDHHC12 zinc finger, DHHC-type containing 12 1.54393
CREB5 cAMP responsive element binding protein 5 1.54258
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.54166
INF2 inverted formin, FH2 and WH2 domain containing 1.5415
NBN nibrin 1.53848
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.53779
ARHGAP18 Rho GTPase activating protein 18 1.53199
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 1.52644
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.52399
BMP8B bone morphogenetic protein 8b 1.52233
SORD sorbitol dehydrogenase 1.51997
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 1.51868
CD40 CD40 molecule, TNF receptor superfamily member 5 1.51762
SRSF7 serine/arginine-rich splicing factor 7 1.51631
GJA3 gap junction protein, alpha 3, 46kDa 1.51578
C1ORF21 chromosome 1 open reading frame 21 1.51505
KIAA0040 KIAA0040 1.50994
MRPL23 mitochondrial ribosomal protein L23 1.50784
ANXA3 annexin A3 1.50716
SPTBN1 spectrin, beta, non-erythrocytic 1 1.50571
PDE9A phosphodiesterase 9A 1.50552
CFAP97 cilia and flagella associated protein 97 1.50465
SETMAR SET domain and mariner transposase fusion gene 1.50287
ASCL4 achaete-scute family bHLH transcription factor 4 1.50269
PKP2 plakophilin 2 1.50181
F3 coagulation factor III (thromboplastin, tissue factor) 1.49705
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.49554
MECOM MDS1 and EVI1 complex locus 1.48912
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 1.48797
SPEN spen family transcriptional repressor 1.48738
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 1.48684
ENKD1 enkurin domain containing 1 1.48671
MYOF myoferlin 1.48544
PREB prolactin regulatory element binding 1.48484
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.48449
CRLF1 cytokine receptor-like factor 1 1.48
ACAD9 acyl-CoA dehydrogenase family, member 9 1.47821
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.47308
IFRD2 interferon-related developmental regulator 2 1.47246
CAMK1D calcium/calmodulin-dependent protein kinase ID 1.46831
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 1.46145
FGF9 fibroblast growth factor 9 1.45874
EPCAM epithelial cell adhesion molecule 1.45671
HES1 hes family bHLH transcription factor 1 1.45574
PLAUR plasminogen activator, urokinase receptor 1.45565
CEMIP cell migration inducing protein, hyaluronan binding 1.45493
PDLIM1 PDZ and LIM domain 1 1.45235
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 1.4523
VDAC3 voltage-dependent anion channel 3 1.45153
LOXL4 lysyl oxidase-like 4 1.45127
HIST1H1E histone cluster 1, H1e 1.45073
GSTP1 glutathione S-transferase pi 1 1.44699
NEK7 NIMA-related kinase 7 1.44638
ANXA11 annexin A11 1.44477
ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 1.44186
DCTPP1 dCTP pyrophosphatase 1 1.43852
GINS2 GINS complex subunit 2 (Psf2 homolog) 1.43486
FARSB phenylalanyl-tRNA synthetase, beta subunit 1.42804
FAM120AOS family with sequence similarity 120A opposite strand 1.42665
RUNX2 runt-related transcription factor 2 1.42153
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.41823
DUSP4 dual specificity phosphatase 4 1.41478
APP amyloid beta (A4) precursor protein 1.41239
NOLC1 nucleolar and coiled-body phosphoprotein 1 1.40302
CPPED1 calcineurin-like phosphoesterase domain containing 1 1.40182
TELO2 telomere maintenance 2 1.40017
GREM1 gremlin 1, DAN family BMP antagonist 1.39477
RHPN2 rhophilin, Rho GTPase binding protein 2 1.39251
PARVA parvin, alpha 1.38924
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 1.38547
SRM spermidine synthase 1.38514
TTC7A tetratricopeptide repeat domain 7A 1.3827
IVNS1ABP influenza virus NS1A binding protein 1.37826
MAMLD1 mastermind-like domain containing 1 1.37634
MB21D2 Mab-21 domain containing 2 1.37354
KRTAP23-1 keratin associated protein 23-1 1.37248
PHB2 prohibitin 2 1.36765
MIS18A MIS18 kinetochore protein A 1.36468
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.36044
TRIB2 tribbles pseudokinase 2 1.35953
ZFP36L2 ZFP36 ring finger protein-like 2 1.35894
NELL2 NEL-like 2 (chicken) 1.35555
ITGA10 integrin, alpha 10 1.35526
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.35469
THSD4 thrombospondin, type I, domain containing 4 1.35437
PHB prohibitin 1.35126
PPAT phosphoribosyl pyrophosphate amidotransferase 1.34546
RGCC regulator of cell cycle 1.34477
NTSR2 neurotensin receptor 2 1.34091
PPARD peroxisome proliferator-activated receptor delta 1.34078
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.33304
ALOX5 arachidonate 5-lipoxygenase 1.33288
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.32843
ORC3 origin recognition complex, subunit 3 1.32788
SYPL2 synaptophysin-like 2 1.32739
EFNB1 ephrin-B1 1.32392
ZNF548 zinc finger protein 548 1.3229
NTHL1 nth endonuclease III-like 1 (E. coli) 1.32095
C19ORF70 chromosome 19 open reading frame 70 1.31942
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 1.31893
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.31858
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.31669
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 1.31343
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.3126
KRT18 keratin 18, type I 1.31212
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 1.30979
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.30755
DEDD2 death effector domain containing 2 1.30545
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.30329
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 1.30059
GRSF1 G-rich RNA sequence binding factor 1 1.29912
PACS2 phosphofurin acidic cluster sorting protein 2 1.29739
AES amino-terminal enhancer of split 1.29678
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 1.29509
RAB38 RAB38, member RAS oncogene family 1.28428
STRADB STE20-related kinase adaptor beta 1.27916
DPYSL3 dihydropyrimidinase-like 3 1.27764
DHRS3 dehydrogenase/reductase (SDR family) member 3 1.27725
KRT8 keratin 8, type II 1.26491
CTSH cathepsin H 1.26274
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 1.26028
NUP210 nucleoporin 210kDa 1.25886
CCNJL cyclin J-like 1.2588
ABHD10 abhydrolase domain containing 10 1.25864
AKAP4 A kinase (PRKA) anchor protein 4 1.2559
ENOSF1 enolase superfamily member 1 1.25146
NOV nephroblastoma overexpressed 1.25097
HEBP1 heme binding protein 1 1.2499
ARRB2 arrestin, beta 2 1.2483
CYB5A cytochrome b5 type A (microsomal) 1.24759
PWP1 PWP1 homolog (S. cerevisiae) 1.24666
TRAPPC2L trafficking protein particle complex 2-like 1.24479
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.24335
KLF11 Kruppel-like factor 11 1.24228
KRT23 keratin 23, type I 1.2407
RNF31 ring finger protein 31 1.23511
BANF1 barrier to autointegration factor 1 1.23416
FGF6 fibroblast growth factor 6 1.23368
RAB1A RAB1A, member RAS oncogene family 1.23214
TXNIP thioredoxin interacting protein 1.23088

decreased expression

Symbol Name Standardized Value
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -4.48341
PARD6B par-6 family cell polarity regulator beta -4.07499
GTPBP2 GTP binding protein 2 -3.77914
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -3.69907
FAM168B family with sequence similarity 168, member B -3.46845
SQSTM1 sequestosome 1 -3.41019
ROPN1L rhophilin associated tail protein 1-like -3.40957
SFPQ splicing factor proline/glutamine-rich -3.305
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -3.29769
IER3 immediate early response 3 -3.23655
SQLE squalene epoxidase -3.03762
DKK1 dickkopf WNT signaling pathway inhibitor 1 -3.00952
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -2.95559
ATF6 activating transcription factor 6 -2.92414
TRAFD1 TRAF-type zinc finger domain containing 1 -2.8403
TIMP1 TIMP metallopeptidase inhibitor 1 -2.83755
DHCR24 24-dehydrocholesterol reductase -2.7834
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) -2.7586
NUCB1 nucleobindin 1 -2.75733
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.72788
IFT88 intraflagellar transport 88 -2.66929
AKAP12 A kinase (PRKA) anchor protein 12 -2.55421
CARD8 caspase recruitment domain family, member 8 -2.55334
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.52827
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.48256
CCDC65 coiled-coil domain containing 65 -2.47756
PRRC2C proline-rich coiled-coil 2C -2.40745
SRSF11 serine/arginine-rich splicing factor 11 -2.40025
FADS1 fatty acid desaturase 1 -2.38876
FUBP1 far upstream element (FUSE) binding protein 1 -2.3637
ADAM17 ADAM metallopeptidase domain 17 -2.36192
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -2.34553
VWA7 von Willebrand factor A domain containing 7 -2.33582
MLEC malectin -2.33498
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) -2.32881
WNT16 wingless-type MMTV integration site family, member 16 -2.32246
CLDN4 claudin 4 -2.31213
LYPLA2 lysophospholipase II -2.30164
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain -2.29776
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -2.29639
TST thiosulfate sulfurtransferase (rhodanese) -2.27199
AARS alanyl-tRNA synthetase -2.26977
LDLR low density lipoprotein receptor -2.20816
SNORD57 small nucleolar RNA, C/D box 57 -2.20184
RYBP RING1 and YY1 binding protein -2.18544
SON SON DNA binding protein -2.18356
EAF1 ELL associated factor 1 -2.1802
TMEM184C transmembrane protein 184C -2.17296
EMC10 ER membrane protein complex subunit 10 -2.15461
CYSTM1 cysteine-rich transmembrane module containing 1 -2.14528
DOT1L DOT1-like histone H3K79 methyltransferase -2.14407
CDC73 cell division cycle 73 -2.13985
MAGEF1 melanoma antigen family F1 -2.13728
ZNF234 zinc finger protein 234 -2.13516
TRRAP transformation/transcription domain-associated protein -2.13301
CERS6 ceramide synthase 6 -2.11595
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.11557
ARHGAP17 Rho GTPase activating protein 17 -2.10618
GLA galactosidase, alpha -2.10234
PTTG1IP pituitary tumor-transforming 1 interacting protein -2.08448
IFNLR1 interferon, lambda receptor 1 -2.07451
JAGN1 jagunal homolog 1 (Drosophila) -2.06467
RSPH3 radial spoke 3 homolog (Chlamydomonas) -2.06296
GDF15 growth differentiation factor 15 -2.05651
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -2.05426
C10ORF67 chromosome 10 open reading frame 67 -2.05131
CLIP1 CAP-GLY domain containing linker protein 1 -2.04581
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.04398
TMEM115 transmembrane protein 115 -2.04164
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -2.03505
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.0065
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -2.00403
SREBF1 sterol regulatory element binding transcription factor 1 -1.9969
KLC2 kinesin light chain 2 -1.99365
MPZL3 myelin protein zero-like 3 -1.98421
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -1.97895
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -1.97855
ANKRD13A ankyrin repeat domain 13A -1.96712
PDIA4 protein disulfide isomerase family A, member 4 -1.94959
C7ORF43 chromosome 7 open reading frame 43 -1.94955
VCAN versican -1.94646
SERINC3 serine incorporator 3 -1.942
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa -1.9409
AFF1 AF4/FMR2 family, member 1 -1.9405
AREG amphiregulin -1.93784
ALOXE3 arachidonate lipoxygenase 3 -1.91592
FAF2 Fas associated factor family member 2 -1.91126
SF3B4 splicing factor 3b, subunit 4, 49kDa -1.89822
KCTD13 potassium channel tetramerization domain containing 13 -1.88846
ZFAND3 zinc finger, AN1-type domain 3 -1.86941
HYOU1 hypoxia up-regulated 1 -1.86856
GPR22 G protein-coupled receptor 22 -1.86823
EXOSC10 exosome component 10 -1.86776
FAM127B family with sequence similarity 127, member B -1.85694
IST1 increased sodium tolerance 1 homolog (yeast) -1.85461
AHI1 Abelson helper integration site 1 -1.8529
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -1.84799
CSN1S2AP casein alpha s2-like A, pseudogene -1.84626
DGKD diacylglycerol kinase, delta 130kDa -1.83472
CD276 CD276 molecule -1.83196
SCARNA7 small Cajal body-specific RNA 7 -1.81175
ANXA10 annexin A10 -1.80632
DRAM1 DNA-damage regulated autophagy modulator 1 -1.79399
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -1.78924
IL27RA interleukin 27 receptor, alpha -1.77362
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -1.77227
MFSD2A major facilitator superfamily domain containing 2A -1.75308
TGOLN2 trans-golgi network protein 2 -1.74714
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -1.7457
ZNF789 zinc finger protein 789 -1.74496
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -1.73569
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -1.73544
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -1.73017
SPINT1 serine peptidase inhibitor, Kunitz type 1 -1.72949
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -1.72379
SPAG1 sperm associated antigen 1 -1.72191
BAZ2A bromodomain adjacent to zinc finger domain, 2A -1.72059
MFGE8 milk fat globule-EGF factor 8 protein -1.71531
CASC3 cancer susceptibility candidate 3 -1.709
PHC2 polyhomeotic homolog 2 (Drosophila) -1.7054
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa -1.68617
NDRG3 NDRG family member 3 -1.68222
ERP44 endoplasmic reticulum protein 44 -1.67895
MLXIPL MLX interacting protein-like -1.66645
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -1.66487
MIA2 melanoma inhibitory activity 2 -1.66407
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.6586
SUN1 Sad1 and UNC84 domain containing 1 -1.65432
MR1 major histocompatibility complex, class I-related -1.64603
AUP1 ancient ubiquitous protein 1 -1.64008
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -1.63861
GSE1 Gse1 coiled-coil protein -1.63816
UBA2 ubiquitin-like modifier activating enzyme 2 -1.63229
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -1.62631
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.62612
HOXA9 homeobox A9 -1.62431
C1ORF210 chromosome 1 open reading frame 210 -1.62154
TAAR1 trace amine associated receptor 1 -1.6149
SGCE sarcoglycan, epsilon -1.61321
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -1.60783
CRELD2 cysteine-rich with EGF-like domains 2 -1.60541
EVI5 ecotropic viral integration site 5 -1.60484
UBE2S ubiquitin-conjugating enzyme E2S -1.60446
TP53INP2 tumor protein p53 inducible nuclear protein 2 -1.60055
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 -1.58943
C16ORF45 chromosome 16 open reading frame 45 -1.58848
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -1.58538
TMEM50A transmembrane protein 50A -1.58399
CD37 CD37 molecule -1.57615
KCTD2 potassium channel tetramerization domain containing 2 -1.57363
FGF19 fibroblast growth factor 19 -1.57322
AXDND1 axonemal dynein light chain domain containing 1 -1.57091
DSE dermatan sulfate epimerase -1.5668
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -1.55976
CRABP2 cellular retinoic acid binding protein 2 -1.55719
GEM GTP binding protein overexpressed in skeletal muscle -1.54943
PRAF2 PRA1 domain family, member 2 -1.54139
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -1.54063
MIR29A microRNA 29a -1.54001
MED13L mediator complex subunit 13-like -1.53876
TMEM248 transmembrane protein 248 -1.53559
LIMA1 LIM domain and actin binding 1 -1.53302
STRN3 striatin, calmodulin binding protein 3 -1.53296
DCTN2 dynactin 2 (p50) -1.52814
TMED4 transmembrane emp24 protein transport domain containing 4 -1.52534
POLR1E polymerase (RNA) I polypeptide E, 53kDa -1.52474
TMEM180 transmembrane protein 180 -1.51886
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -1.51635
LAMB1 laminin, beta 1 -1.51587
CHIC2 cysteine-rich hydrophobic domain 2 -1.50295
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -1.49795
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.49794
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -1.49332
WIPI1 WD repeat domain, phosphoinositide interacting 1 -1.48923
LPAR5 lysophosphatidic acid receptor 5 -1.48193
PPP1R18 protein phosphatase 1, regulatory subunit 18 -1.47995
ERN1 endoplasmic reticulum to nucleus signaling 1 -1.47561
CDC26 cell division cycle 26 -1.47139
TRAM2 translocation associated membrane protein 2 -1.46964
INSIG1 insulin induced gene 1 -1.46486
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -1.46446
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -1.46305
NFE2L1 nuclear factor, erythroid 2-like 1 -1.45257
CRAT carnitine O-acetyltransferase -1.44808
CUL9 cullin 9 -1.44652
SCAMP2 secretory carrier membrane protein 2 -1.43982
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.439
CIAO1 cytosolic iron-sulfur assembly component 1 -1.43804
CTXN1 cortexin 1 -1.43782
DCBLD2 discoidin, CUB and LCCL domain containing 2 -1.43301
GOLM1 golgi membrane protein 1 -1.43108
NCOA3 nuclear receptor coactivator 3 -1.42904
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -1.4208
RHOF ras homolog family member F (in filopodia) -1.42059
MRPS27 mitochondrial ribosomal protein S27 -1.42032
MAN2B2 mannosidase, alpha, class 2B, member 2 -1.41965
SNORD79 small nucleolar RNA, C/D box 79 -1.41214
WBP1L WW domain binding protein 1-like -1.40684
ZNF865 zinc finger protein 865 -1.40388
FASN fatty acid synthase -1.4019
FN1 fibronectin 1 -1.39884
R3HDM4 R3H domain containing 4 -1.39599
ERMN ermin, ERM-like protein -1.39577
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -1.39465
BEX2 brain expressed X-linked 2 -1.39039
BMI1 BMI1 proto-oncogene, polycomb ring finger -1.3892
LOC440173 uncharacterized LOC440173 -1.38557
PHF21A PHD finger protein 21A -1.3828
TMED9 transmembrane emp24 protein transport domain containing 9 -1.38258
SLC26A11 solute carrier family 26 (anion exchanger), member 11 -1.38258
TFRC transferrin receptor -1.3799
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -1.37904
STK38L serine/threonine kinase 38 like -1.37791
SKAP2 src kinase associated phosphoprotein 2 -1.37647
KLF12 Kruppel-like factor 12 -1.37536
FAM117B family with sequence similarity 117, member B -1.37354
SDC3 syndecan 3 -1.37343
TULP3 tubby like protein 3 -1.3713
SMIM14 small integral membrane protein 14 -1.3712
SURF4 surfeit 4 -1.36884
BPTF bromodomain PHD finger transcription factor -1.36467
CLEC16A C-type lectin domain family 16, member A -1.3606
EFTUD2 elongation factor Tu GTP binding domain containing 2 -1.3561
IP6K2 inositol hexakisphosphate kinase 2 -1.35486
AMOTL1 angiomotin like 1 -1.35376
ANKRD40 ankyrin repeat domain 40 -1.35201
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -1.34928
TMED2 transmembrane emp24 domain trafficking protein 2 -1.34899
TBC1D20 TBC1 domain family, member 20 -1.34687
CPM carboxypeptidase M -1.34392
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -1.34184
FADS3 fatty acid desaturase 3 -1.33935
C7ORF72 chromosome 7 open reading frame 72 -1.33916
TUBB4A tubulin, beta 4A class IVa -1.33857
YIPF3 Yip1 domain family, member 3 -1.33784
AHDC1 AT hook, DNA binding motif, containing 1 -1.33718
SATB1 SATB homeobox 1 -1.33289
ADPRHL1 ADP-ribosylhydrolase like 1 -1.33093
UBE2W ubiquitin-conjugating enzyme E2W (putative) -1.33008
NPC1 Niemann-Pick disease, type C1 -1.32938
PHLDB1 pleckstrin homology-like domain, family B, member 1 -1.32869
SELT selenoprotein T -1.32855
TSPYL4 TSPY-like 4 -1.3248
FAM214B family with sequence similarity 214, member B -1.32429
MYH15 myosin, heavy chain 15 -1.32195
ELOVL6 ELOVL fatty acid elongase 6 -1.32177
FADS2 fatty acid desaturase 2 -1.32173
NAGK N-acetylglucosamine kinase -1.32074
LMO7 LIM domain 7 -1.31855
ZSCAN16 zinc finger and SCAN domain containing 16 -1.31635
STAC3 SH3 and cysteine rich domain 3 -1.31372
KIAA1217 KIAA1217 -1.31306
BSDC1 BSD domain containing 1 -1.31061
MGC57346 ADP-ribosylation factor pseudogene -1.30814
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -1.3069
ULBP1 UL16 binding protein 1 -1.30375
LOC100133091 uncharacterized LOC100133091 -1.30224
TRIM62 tripartite motif containing 62 -1.30111
YME1L1 YME1-like 1 ATPase -1.30022
FOXJ2 forkhead box J2 -1.2966
AGA aspartylglucosaminidase -1.29554
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -1.29401
SGSH N-sulfoglucosamine sulfohydrolase -1.2936
ERCC3 excision repair cross-complementation group 3 -1.29353
TBC1D19 TBC1 domain family, member 19 -1.29261
PSENEN presenilin enhancer gamma secretase subunit -1.28982
CDCP1 CUB domain containing protein 1 -1.2861
GLG1 golgi glycoprotein 1 -1.28213
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -1.28193
FHDC1 FH2 domain containing 1 -1.27825
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -1.27667
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -1.27628
ZNF354A zinc finger protein 354A -1.26917
S100A10 S100 calcium binding protein A10 -1.26587
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -1.26514
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -1.26343
ELMOD3 ELMO/CED-12 domain containing 3 -1.25072
LRP10 low density lipoprotein receptor-related protein 10 -1.24935
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -1.24392
CEP350 centrosomal protein 350kDa -1.23956
FNBP4 formin binding protein 4 -1.23258
KPNB1 karyopherin (importin) beta 1 -1.23031
WSB2 WD repeat and SOCS box containing 2 -1.23
GRN granulin -1.22874
OLFM2 olfactomedin 2 -1.22529
ABHD13 abhydrolase domain containing 13 -1.22088
MAOB monoamine oxidase B -1.21945
CLDN7 claudin 7 -1.2165
MIR221 microRNA 221 -1.21205
BHLHE40 basic helix-loop-helix family, member e40 -1.21204
NEU1 sialidase 1 (lysosomal sialidase) -1.21101
TP53INP1 tumor protein p53 inducible nuclear protein 1 -1.20856
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.20781
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -1.20684
ZNF595 zinc finger protein 595 -1.20392
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.20373
NUP188 nucleoporin 188kDa -1.20348
NRARP NOTCH-regulated ankyrin repeat protein -1.2031
CHD5 chromodomain helicase DNA binding protein 5 -1.20264
ELMO2 engulfment and cell motility 2 -1.20143
Funding