| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin-dependent kinase 2|This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 1017) |
| External Link | https://ncbi.nlm.nih.gov/gene/1017 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the CDK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0125085 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0108209 |
| AREG | amphiregulin | 0.0106691 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0103999 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00858678 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00806128 |
| MX1 | MX dynamin-like GTPase 1 | 0.00799017 |
| SMAD3 | SMAD family member 3 | 0.00791505 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00773347 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00768442 |
| PTHLH | parathyroid hormone-like hormone | 0.00756043 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00754904 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00753362 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00748082 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00740609 |
| IFI44L | interferon-induced protein 44-like | 0.00723491 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00701324 |
| SP110 | SP110 nuclear body protein | 0.0069527 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00676797 |
| ABLIM1 | actin binding LIM protein 1 | 0.00671112 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00667384 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0066355 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00663216 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00657538 |
| TOX3 | TOX high mobility group box family member 3 | 0.00650825 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00639226 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00623502 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00615217 |
| HMOX1 | heme oxygenase 1 | 0.00612636 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00605492 |
| ACKR3 | atypical chemokine receptor 3 | 0.00603883 |
| NEBL | nebulette | 0.00600175 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00593526 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00593433 |
| TSPAN8 | tetraspanin 8 | 0.00582269 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00581319 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00580243 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00569612 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00553798 |
| PROM1 | prominin 1 | 0.00552532 |
| GPX2 | glutathione peroxidase 2 | 0.00550969 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00550192 |
| IL17RB | interleukin 17 receptor B | 0.0054331 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00539176 |
| PEG3 | paternally expressed 3 | 0.00535374 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00528396 |
| KLF6 | Kruppel-like factor 6 | 0.00527001 |
| MX2 | MX dynamin-like GTPase 2 | 0.0052488 |
| NRCAM | neuronal cell adhesion molecule | 0.00524476 |
| IL1B | interleukin 1, beta | 0.00523231 |
| TJP2 | tight junction protein 2 | 0.00519922 |
| MVP | major vault protein | 0.00513619 |
| ANXA3 | annexin A3 | 0.0051293 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00512061 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00511687 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00511447 |
| IRF7 | interferon regulatory factor 7 | 0.00508283 |
| KLF2 | Kruppel-like factor 2 | 0.0050636 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00504111 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00503406 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00502118 |
| PLAT | plasminogen activator, tissue | 0.00501587 |
| IFI44 | interferon-induced protein 44 | 0.00501404 |
| TFF1 | trefoil factor 1 | 0.0049872 |
| ZNF91 | zinc finger protein 91 | 0.00498695 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00495005 |
| RRAGD | Ras-related GTP binding D | 0.00494062 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00493775 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00493009 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0048878 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00486372 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00485645 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00485267 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00484443 |
| LIF | leukemia inhibitory factor | 0.00483689 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00481224 |
| RHOC | ras homolog family member C | 0.00480064 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00479622 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00478991 |
| TSPAN1 | tetraspanin 1 | 0.0047704 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00476226 |
| FILIP1L | filamin A interacting protein 1-like | 0.00472817 |
| MXRA7 | matrix-remodelling associated 7 | 0.0047185 |
| CAST | calpastatin | 0.00471824 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00471085 |
| KRT23 | keratin 23, type I | 0.0047102 |
| MCAM | melanoma cell adhesion molecule | 0.00470976 |
| MT1X | metallothionein 1X | 0.004679 |
| GATA6 | GATA binding protein 6 | 0.00467256 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00467095 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00463789 |
| PALLD | palladin, cytoskeletal associated protein | 0.00463552 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0046245 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00459267 |
| FOSL2 | FOS-like antigen 2 | 0.00454673 |
| SGCE | sarcoglycan, epsilon | 0.0045405 |
| STK39 | serine threonine kinase 39 | 0.00453991 |
| AOC1 | amine oxidase, copper containing 1 | 0.00453216 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00451774 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00449424 |
| XIC | X chromosome inactivation center | 0.00449408 |
| MT2A | metallothionein 2A | 0.00449142 |
| KRT14 | keratin 14, type I | 0.00447867 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00447578 |
| COQ8A | coenzyme Q8A | 0.004475 |
| ATF3 | activating transcription factor 3 | 0.00447458 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00444627 |
| PPIF | peptidylprolyl isomerase F | 0.00444598 |
| VWF | von Willebrand factor | 0.00444377 |
| SP100 | SP100 nuclear antigen | 0.004439 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00442279 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 0.00442048 |
| FHL1 | four and a half LIM domains 1 | 0.00441477 |
| TUBB2B | tubulin, beta 2B class IIb | 0.0044123 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00441064 |
| LAMC2 | laminin, gamma 2 | 0.00434577 |
| CHGB | chromogranin B | 0.00434336 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00434032 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00433881 |
| LIPG | lipase, endothelial | 0.00432763 |
| CRYAB | crystallin, alpha B | 0.00432077 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00430642 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00430512 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0043037 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0042975 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00428487 |
| GNAS | GNAS complex locus | 0.00427853 |
| FERMT1 | fermitin family member 1 | 0.00427692 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00426495 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00425082 |
| EGR1 | early growth response 1 | 0.00422653 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00422177 |
| DAXX | death-domain associated protein | 0.00422127 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00421825 |
| IL32 | interleukin 32 | 0.00420881 |
| TUFT1 | tuftelin 1 | 0.00416986 |
| RGS5 | regulator of G-protein signaling 5 | 0.00413145 |
| LAMA3 | laminin, alpha 3 | 0.00412428 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00412118 |
| RAB29 | RAB29, member RAS oncogene family | 0.00411854 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00410203 |
| CCNA2 | cyclin A2 | 0.00409508 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00407439 |
| MLF1 | myeloid leukemia factor 1 | 0.0040742 |
| TOX | thymocyte selection-associated high mobility group box | 0.00407312 |
| CORO1A | coronin, actin binding protein, 1A | 0.00406755 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00405979 |
| CLTB | clathrin, light chain B | 0.00403343 |
| ECM1 | extracellular matrix protein 1 | 0.00401671 |
| MAGED2 | melanoma antigen family D2 | 0.00401592 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00401541 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00401537 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.004015 |
| PEG10 | paternally expressed 10 | 0.0040138 |
| TSPAN3 | tetraspanin 3 | 0.00400475 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00399933 |
| TRIM16 | tripartite motif containing 16 | 0.00397887 |
| JAM2 | junctional adhesion molecule 2 | 0.0039752 |
| OGN | osteoglycin | 0.00397501 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00396477 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00396272 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00395412 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0039449 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00393655 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00393449 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00392405 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.0039112 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00390144 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00388416 |
| PLCE1 | phospholipase C, epsilon 1 | 0.00388232 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00388218 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00388056 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00387234 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.0038652 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00385111 |
| RND3 | Rho family GTPase 3 | 0.00384652 |
| RRAD | Ras-related associated with diabetes | 0.00384462 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.00384319 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00383875 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00383136 |
| MCL1 | myeloid cell leukemia 1 | 0.00381598 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00380491 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0037878 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.003775 |
| IER3 | immediate early response 3 | 0.00377422 |
| S100A14 | S100 calcium binding protein A14 | 0.00376879 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.0037471 |
| CERS6 | ceramide synthase 6 | 0.00374586 |
| PITX3 | paired-like homeodomain 3 | 0.00374283 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00373745 |
| RGS4 | regulator of G-protein signaling 4 | 0.00373556 |
| CCN2 | cellular communication network factor 2 | 0.00373429 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00373396 |
| EDN3 | endothelin 3 | 0.00373109 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.00372769 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0037271 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00372609 |
| IL1A | interleukin 1, alpha | 0.00372467 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0037239 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00371643 |
| SPATA20 | spermatogenesis associated 20 | 0.00371584 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00371266 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00371205 |
| EFNB2 | ephrin-B2 | 0.00370725 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00370628 |
| IL6 | interleukin 6 | 0.00370406 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0037029 |
| RNASET2 | ribonuclease T2 | 0.00369858 |
| ITGB4 | integrin, beta 4 | 0.00369577 |
| FAM107A | family with sequence similarity 107, member A | 0.00369169 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00368283 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00368252 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00366536 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0036586 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00364948 |
| RBM34 | RNA binding motif protein 34 | 0.00364793 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00364769 |
| ANK2 | ankyrin 2, neuronal | 0.00363431 |
| GSK3B | glycogen synthase kinase 3 beta | 0.00363319 |
| POPDC3 | popeye domain containing 3 | 0.00362499 |
| COG7 | component of oligomeric golgi complex 7 | 0.00362113 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.0036063 |
| MT1H | metallothionein 1H | 0.00360265 |
| TGFA | transforming growth factor, alpha | 0.00360069 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00359634 |
| AOX1 | aldehyde oxidase 1 | 0.00359222 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00359144 |
| CH25H | cholesterol 25-hydroxylase | 0.00358842 |
| IRF1 | interferon regulatory factor 1 | 0.00358292 |
| ZYX | zyxin | 0.00357946 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00357808 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00357763 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00357083 |
| LIMK2 | LIM domain kinase 2 | 0.0035704 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00356893 |
| PRSS3 | protease, serine, 3 | 0.00356513 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00356168 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00355379 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0035529 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00354734 |
| F2R | coagulation factor II (thrombin) receptor | 0.00354241 |
| WLS | wntless Wnt ligand secretion mediator | 0.00353625 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00353449 |
| FCGBP | Fc fragment of IgG binding protein | 0.00353413 |
| APOL2 | apolipoprotein L, 2 | 0.0035337 |
| FLNB | filamin B, beta | 0.00352694 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00352628 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00352594 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00352423 |
| NCALD | neurocalcin delta | 0.0035205 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KIF20A | kinesin family member 20A | -0.015138 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00952581 |
| PLK1 | polo-like kinase 1 | -0.00919947 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0091368 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0088666 |
| NEK2 | NIMA-related kinase 2 | -0.00883034 |
| KIF14 | kinesin family member 14 | -0.0082805 |
| CDC20 | cell division cycle 20 | -0.0082567 |
| CENPF | centromere protein F, 350/400kDa | -0.00756822 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00747493 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00746044 |
| CDK2 | cyclin-dependent kinase 2 | -0.00723191 |
| LUM | lumican | -0.00697239 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00694441 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00675691 |
| NDC80 | NDC80 kinetochore complex component | -0.006728 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00667653 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00649611 |
| FAM3C | family with sequence similarity 3, member C | -0.00641457 |
| PTTG1 | pituitary tumor-transforming 1 | -0.00632745 |
| NELL2 | NEL-like 2 (chicken) | -0.00630845 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.00629019 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00617136 |
| LTF | lactotransferrin | -0.00615571 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00614762 |
| OIP5 | Opa interacting protein 5 | -0.00611854 |
| AURKA | aurora kinase A | -0.00611113 |
| DEPDC1 | DEP domain containing 1 | -0.00609706 |
| CDCA3 | cell division cycle associated 3 | -0.0060552 |
| CCNB2 | cyclin B2 | -0.00604954 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00601522 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00599789 |
| HMGB3 | high mobility group box 3 | -0.00598981 |
| FOXM1 | forkhead box M1 | -0.00598839 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00589838 |
| CENPE | centromere protein E, 312kDa | -0.00586827 |
| HMGB2 | high mobility group box 2 | -0.00579567 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00576813 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00567101 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00566534 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00565667 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.00561726 |
| ATF1 | activating transcription factor 1 | -0.00558248 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00557907 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00557683 |
| KIF11 | kinesin family member 11 | -0.00554188 |
| NTS | neurotensin | -0.00552831 |
| TROAP | trophinin associated protein | -0.00549552 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00544715 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00542494 |
| CEP55 | centrosomal protein 55kDa | -0.00536574 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -0.00533813 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00528442 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00527697 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00523254 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00522646 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00521899 |
| MDFIC | MyoD family inhibitor domain containing | -0.00519421 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00517482 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00513791 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00505913 |
| SMC4 | structural maintenance of chromosomes 4 | -0.00502541 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00496879 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00494647 |
| TMPO | thymopoietin | -0.00489123 |
| KIF4A | kinesin family member 4A | -0.0048744 |
| LMNB2 | lamin B2 | -0.00486739 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00484694 |
| LBR | lamin B receptor | -0.00481937 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.00481679 |
| PIMREG | PICALM interacting mitotic regulator | -0.00480623 |
| MMP9 | matrix metallopeptidase 9 | -0.00480509 |
| SPP1 | secreted phosphoprotein 1 | -0.00476571 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00475487 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00472115 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00466044 |
| KIF23 | kinesin family member 23 | -0.0046303 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -0.0046116 |
| CDC25B | cell division cycle 25B | -0.00460541 |
| NEMP1 | nuclear envelope integral membrane protein 1 | -0.00460431 |
| RESF1 | retroelement silencing factor 1 | -0.00459263 |
| METTL7A | methyltransferase like 7A | -0.00458132 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00458085 |
| PBK | PDZ binding kinase | -0.00454644 |
| UBE2N | ubiquitin-conjugating enzyme E2N | -0.00453417 |
| HBD | hemoglobin, delta | -0.00452684 |
| ANGEL2 | angel homolog 2 (Drosophila) | -0.00449047 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00447584 |
| TWF1 | twinfilin actin binding protein 1 | -0.00447218 |
| DCT | dopachrome tautomerase | -0.00446371 |
| CDCA8 | cell division cycle associated 8 | -0.00445804 |
| AZF1 | azoospermia factor 1 | -0.00444208 |
| CDK19 | cyclin-dependent kinase 19 | -0.0044406 |
| CLC | Charcot-Leyden crystal galectin | -0.00439785 |
| CBX5 | chromobox homolog 5 | -0.00437787 |
| KIF18A | kinesin family member 18A | -0.00437377 |
| H2AX | H2A.X variant histone | -0.00436368 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00435691 |
| ANO3 | anoctamin 3 | -0.0043381 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -0.00432164 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0043128 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.0043058 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00428365 |
| SHROOM2 | shroom family member 2 | -0.00427728 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00427142 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00426901 |
| PLXNC1 | plexin C1 | -0.00425712 |
| PDGFC | platelet derived growth factor C | -0.00425657 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.00424514 |
| HMGB1 | high mobility group box 1 | -0.00424296 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.00423999 |
| CDK1 | cyclin-dependent kinase 1 | -0.00421838 |
| PMEL | premelanosome protein | -0.00419682 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | -0.00419439 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00418861 |
| TTK | TTK protein kinase | -0.00418065 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.0041803 |
| ASF1A | anti-silencing function 1A histone chaperone | -0.00417217 |
| UBL3 | ubiquitin-like 3 | -0.00416176 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00415675 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00415047 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.0041498 |
| COL1A2 | collagen, type I, alpha 2 | -0.00414134 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.0041373 |
| TPX2 | TPX2, microtubule-associated | -0.00413253 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00412747 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00412442 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | -0.00412346 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00408013 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.00407746 |
| TRAPPC8 | trafficking protein particle complex 8 | -0.00402582 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00398574 |
| WASHC4 | WASH complex subunit 4 | -0.00398156 |
| WTAP | Wilms tumor 1 associated protein | -0.00397562 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00397097 |
| FBXO5 | F-box protein 5 | -0.00396222 |
| NUP50 | nucleoporin 50kDa | -0.00395812 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | -0.00395613 |
| ZNF586 | zinc finger protein 586 | -0.00395174 |
| PARPBP | PARP1 binding protein | -0.00393802 |
| HJURP | Holliday junction recognition protein | -0.00393537 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene | -0.00392753 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.00389592 |
| KIF18B | kinesin family member 18B | -0.00389587 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00389383 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.00388742 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00387382 |
| FBLN1 | fibulin 1 | -0.00386637 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00386529 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00386276 |
| DBF4 | DBF4 zinc finger | -0.0038566 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.00385613 |
| SETD1B | SET domain containing 1B | -0.00384922 |
| C4BPA | complement component 4 binding protein, alpha | -0.00384362 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00384175 |
| SPAG5 | sperm associated antigen 5 | -0.00383284 |
| PRKCB | protein kinase C, beta | -0.00381557 |
| TMX1 | thioredoxin-related transmembrane protein 1 | -0.00380287 |
| RAD21 | RAD21 homolog (S. pombe) | -0.00380273 |
| LARP4 | La ribonucleoprotein domain family, member 4 | -0.0038018 |
| H2AFV | H2A histone family, member V | -0.003794 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | -0.00377871 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00375806 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00375763 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00375607 |
| CDC25C | cell division cycle 25C | -0.00375114 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00374213 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00373666 |
| EMP3 | epithelial membrane protein 3 | -0.00373444 |
| FGA | fibrinogen alpha chain | -0.00371189 |
| RXRA | retinoid X receptor, alpha | -0.00370872 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00370092 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00367531 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.00366595 |
| AURKB | aurora kinase B | -0.00363967 |
| CP | ceruloplasmin (ferroxidase) | -0.00363852 |
| CALR | calreticulin | -0.00363354 |
| FBXW2 | F-box and WD repeat domain containing 2 | -0.00363328 |
| HP | haptoglobin | -0.00361568 |
| INSIG1 | insulin induced gene 1 | -0.00360697 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.00360651 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00360399 |
| FZD2 | frizzled class receptor 2 | -0.00358316 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00358046 |
| TARDBP | TAR DNA binding protein | -0.00357417 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.00357219 |
| HOXB2 | homeobox B2 | -0.00356192 |
| CENPA | centromere protein A | -0.00355886 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.00355156 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.003544 |
| CD48 | CD48 molecule | -0.00353392 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00352988 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00352834 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.003517 |
| LTA4H | leukotriene A4 hydrolase | -0.00351398 |
| ATMIN | ATM interactor | -0.00350906 |
| CA12 | carbonic anhydrase XII | -0.00350776 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0035035 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00350086 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00349489 |
| KIF15 | kinesin family member 15 | -0.00349325 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.00349308 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00349121 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00348914 |
| ACTR6 | ARP6 actin-related protein 6 homolog (yeast) | -0.0034814 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B | -0.00347585 |
| PRUNE1 | prune exopolyphosphatase 1 | -0.00347407 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00347148 |
| TRMT5 | tRNA methyltransferase 5 | -0.00347074 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N | -0.00346706 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00346363 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00345533 |
| YME1L1 | YME1-like 1 ATPase | -0.0034497 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00344508 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00344341 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.003438 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00342824 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00342108 |
| FOXF2 | forkhead box F2 | -0.00342097 |
| ESR1 | estrogen receptor 1 | -0.00341748 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00341673 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00340618 |
| NID2 | nidogen 2 (osteonidogen) | -0.00340373 |
| LIN28A | lin-28 homolog A (C. elegans) | -0.00340269 |
| UNC50 | unc-50 homolog (C. elegans) | -0.00340146 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00340059 |
| FBXL14 | F-box and leucine-rich repeat protein 14 | -0.00339156 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00336812 |
| SEPHS1 | selenophosphate synthetase 1 | -0.0033563 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00335349 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00334321 |
| PFDN5 | prefoldin subunit 5 | -0.00332364 |
| TSFM | Ts translation elongation factor, mitochondrial | -0.0033187 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00331512 |
| SIRT3 | sirtuin 3 | -0.00330755 |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa | -0.00330711 |
| TIMELESS | timeless circadian clock | -0.00330547 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | -0.00329981 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00329553 |
| ANXA4 | annexin A4 | -0.00329227 |
| KIF20B | kinesin family member 20B | -0.00329136 |
| TDG | thymine-DNA glycosylase | -0.00329098 |
| PANK3 | pantothenate kinase 3 | -0.00329081 |
| SSBP3 | single stranded DNA binding protein 3 | -0.00328427 |
| DCP2 | decapping mRNA 2 | -0.00328118 |
| BTBD2 | BTB (POZ) domain containing 2 | -0.00327618 |
| CRYM | crystallin, mu | -0.00325044 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00324955 |
| SEH1L | SEH1-like (S. cerevisiae) | -0.00324197 |
