CDK2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description cyclin-dependent kinase 2|This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 1017)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_CDK2
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Genes

71 co-expressed genes for CDK2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
AFG3L2 AFG3-like AAA ATPase 2
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ATXN2L ataxin 2-like
BUB3 BUB3 mitotic checkpoint protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDK2 cyclin-dependent kinase 2
CLTC clathrin, heavy chain (Hc)
COPS6 COP9 signalosome subunit 6
CS citrate synthase
CTDNEP1 CTD nuclear envelope phosphatase 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DEK DEK proto-oncogene
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DOCK3 dedicator of cytokinesis 3
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EBP emopamil binding protein (sterol isomerase)
EIF3I eukaryotic translation initiation factor 3, subunit I
ESYT1 extended synaptotagmin-like protein 1
ETF1 eukaryotic translation termination factor 1
FUS FUS RNA binding protein
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GTF2A2 general transcription factor IIA, 2, 12kDa
H2AFZ H2A histone family, member Z
HDAC2 histone deacetylase 2
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
ILF2 interleukin enhancer binding factor 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LRPPRC leucine-rich pentatricopeptide repeat containing
MCM2 minichromosome maintenance complex component 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NONO non-POU domain containing, octamer-binding
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP188 nucleoporin 188kDa
NUP62 nucleoporin 62kDa
PABPN1 poly(A) binding protein, nuclear 1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF8 pre-mRNA processing factor 8
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PWP1 PWP1 homolog (S. cerevisiae)
RPA2 replication protein A2, 32kDa
RUVBL2 RuvB-like AAA ATPase 2
SCARB1 scavenger receptor class B, member 1
SEPT7 septin 7
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SRRM1 serine/arginine repetitive matrix 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSRP1 structure specific recognition protein 1
STARD7 StAR-related lipid transfer (START) domain containing 7
SUMO2 small ubiquitin-like modifier 2
TCEA1 transcription elongation factor A (SII), 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEX261 testis expressed 261
U2AF1 U2 small nuclear RNA auxiliary factor 1
XPO6 exportin 6
XPO7 exportin 7
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZNF131 zinc finger protein 131