CDK5 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description cyclin-dependent kinase 5|This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] (NCBI Entrez Gene Database, 1020)
Similar Terms
Downloads & Tools

Genes

100 substrates of the kinase CDK5 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
KMT2B lysine (K)-specific methyltransferase 2B
KMT2D lysine (K)-specific methyltransferase 2D
ZCCHC8 zinc finger, CCHC domain containing 8
ARID3A AT rich interactive domain 3A (BRIGHT-like)
NECAB2 N-terminal EF-hand calcium binding protein 2
BBC3 BCL2 binding component 3
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
FOXL2 forkhead box L2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
USP24 ubiquitin specific peptidase 24
INPPL1 inositol polyphosphate phosphatase-like 1
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
AFAP1 actin filament associated protein 1
PERM1 PPARGC1 and ESRR induced regulator, muscle 1
EP400 E1A binding protein p400
BICC1 BicC family RNA binding protein 1
MAP7D2 MAP7 domain containing 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
WTIP Wilms tumor 1 interacting protein
EPS8L2 EPS8-like 2
ENTHD2 ENTH domain containing 2
E2F4 E2F transcription factor 4, p107/p130-binding
NKX2-4 NK2 homeobox 4
ZNF608 zinc finger protein 608
ZMYM3 zinc finger, MYM-type 3
ADD2 adducin 2 (beta)
CCDC137 coiled-coil domain containing 137
STMN2 stathmin 2
RBL1 retinoblastoma-like 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
SEC62 SEC62 homolog (S. cerevisiae)
PHIP pleckstrin homology domain interacting protein
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
CNOT10 CCR4-NOT transcription complex, subunit 10
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
APC2 adenomatosis polyposis coli 2
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
SH3PXD2B SH3 and PX domains 2B
FAM178B family with sequence similarity 178, member B
CCDC97 coiled-coil domain containing 97
RABEPK Rab9 effector protein with kelch motifs
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PRR11 proline rich 11
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
BEST3 bestrophin 3
KIF13B kinesin family member 13B
MAP1A microtubule-associated protein 1A
KIAA1217 KIAA1217
EMILIN1 elastin microfibril interfacer 1
BCOR BCL6 corepressor
PROSER3 proline and serine rich 3
NIPBL Nipped-B homolog (Drosophila)
RB1 retinoblastoma 1
ZFPL1 zinc finger protein-like 1
MZT2B mitotic spindle organizing protein 2B
ZC3H13 zinc finger CCCH-type containing 13
AKIRIN1 akirin 1
ZNF335 zinc finger protein 335
ZNF592 zinc finger protein 592
DNLZ DNL-type zinc finger
GAS2L1 growth arrest-specific 2 like 1
TBKBP1 TBK1 binding protein 1
FBF1 Fas (TNFRSF6) binding factor 1
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
KIAA1522 KIAA1522
NCOA2 nuclear receptor coactivator 2
MTX1 metaxin 1
WNK3 WNK lysine deficient protein kinase 3
COL9A2 collagen, type IX, alpha 2
UHRF1BP1L UHRF1 binding protein 1-like
LIG3 ligase III, DNA, ATP-dependent
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
C19ORF57 chromosome 19 open reading frame 57
BEGAIN brain-enriched guanylate kinase-associated
NOP9 NOP9 nucleolar protein
TMC8 transmembrane channel-like 8
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
SPEG SPEG complex locus
PKN3 protein kinase N3
CIC capicua transcriptional repressor
MKI67 marker of proliferation Ki-67
CRY2 cryptochrome circadian clock 2
TPR translocated promoter region, nuclear basket protein
MED9 mediator complex subunit 9
IQSEC1 IQ motif and Sec7 domain 1
HDLBP high density lipoprotein binding protein
FOXO1 forkhead box O1
ZNF532 zinc finger protein 532
MSL3 male-specific lethal 3 homolog (Drosophila)
SVIL supervillin
PPP1R3D protein phosphatase 1, regulatory subunit 3D
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
RIOK3 RIO kinase 3
SCNM1 sodium channel modifier 1
KIF1C kinesin family member 1C
ANKRD34B ankyrin repeat domain 34B