| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin-dependent kinase 6|The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 1021) |
| External Link | https://ncbi.nlm.nih.gov/gene/1021 |
| Similar Terms | |
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499 genes differentially expressed following the CDK6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0291914 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0226688 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0203653 |
| IFI44L | interferon-induced protein 44-like | 0.0188454 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0183156 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0169874 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0151767 |
| XIC | X chromosome inactivation center | 0.014746 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0143832 |
| ADIRF | adipogenesis regulatory factor | 0.0143239 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0136722 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0131528 |
| MX1 | MX dynamin-like GTPase 1 | 0.0126684 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0124051 |
| COG7 | component of oligomeric golgi complex 7 | 0.0123645 |
| HOPX | HOP homeobox | 0.0122563 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0121766 |
| ECM1 | extracellular matrix protein 1 | 0.0116861 |
| MX2 | MX dynamin-like GTPase 2 | 0.011675 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.011667 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.011473 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0113714 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0113664 |
| GPR137B | G protein-coupled receptor 137B | 0.0112345 |
| DEFB1 | defensin, beta 1 | 0.0112147 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0111809 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0110607 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.0110397 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0107879 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0107868 |
| KLF10 | Kruppel-like factor 10 | 0.0107469 |
| APOL1 | apolipoprotein L, 1 | 0.0107152 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0106927 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0106608 |
| BST2 | bone marrow stromal cell antigen 2 | 0.010422 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.0103869 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.0102046 |
| XAF1 | XIAP associated factor 1 | 0.0101802 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0101772 |
| IRF7 | interferon regulatory factor 7 | 0.0101107 |
| CLU | clusterin | 0.0100681 |
| IFI44 | interferon-induced protein 44 | 0.0100481 |
| CFB | complement factor B | 0.0100043 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00993856 |
| RNASET2 | ribonuclease T2 | 0.00991215 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0098463 |
| LBH | limb bud and heart development | 0.00972467 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00971023 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00970428 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00969684 |
| MT1X | metallothionein 1X | 0.00967181 |
| MT1E | metallothionein 1E | 0.00964877 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00959651 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00954662 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00954027 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00948466 |
| TARP | TCR gamma alternate reading frame protein | 0.00946911 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00946008 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.0094486 |
| CFI | complement factor I | 0.0094026 |
| ABLIM1 | actin binding LIM protein 1 | 0.00937846 |
| MXRA7 | matrix-remodelling associated 7 | 0.00929207 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00923358 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00922505 |
| MT1F | metallothionein 1F | 0.00908734 |
| RGS4 | regulator of G-protein signaling 4 | 0.00901708 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00901644 |
| IFI35 | interferon-induced protein 35 | 0.00899646 |
| IRF9 | interferon regulatory factor 9 | 0.00899087 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00884488 |
| MT1H | metallothionein 1H | 0.00882582 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00882172 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.0088038 |
| ITGAV | integrin, alpha V | 0.00878566 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00878173 |
| IL6R | interleukin 6 receptor | 0.00876954 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00873784 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0087209 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00868694 |
| LAMA5 | laminin, alpha 5 | 0.00859177 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00858825 |
| LCN2 | lipocalin 2 | 0.00858721 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00858313 |
| HTRA1 | HtrA serine peptidase 1 | 0.00857144 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00854779 |
| TRIM22 | tripartite motif containing 22 | 0.00854173 |
| NOTCH2NL | notch 2 N-terminal like | 0.00852734 |
| GPX1 | glutathione peroxidase 1 | 0.00849399 |
| TLR4 | toll-like receptor 4 | 0.00848416 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00846781 |
| CTSD | cathepsin D | 0.00845236 |
| RPS27L | ribosomal protein S27-like | 0.00843005 |
| CCN2 | cellular communication network factor 2 | 0.00832567 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00827969 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00827534 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00825303 |
| S100P | S100 calcium binding protein P | 0.00823798 |
| SP110 | SP110 nuclear body protein | 0.00820052 |
| FRMD4B | FERM domain containing 4B | 0.00810685 |
| FN1 | fibronectin 1 | 0.00809862 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.008087 |
| APOL2 | apolipoprotein L, 2 | 0.00807665 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00806112 |
| NRCAM | neuronal cell adhesion molecule | 0.0080583 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00805556 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.0080447 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00803208 |
| PDGFC | platelet derived growth factor C | 0.0080097 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00800486 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00799725 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0079435 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00790789 |
| MSLN | mesothelin | 0.00778497 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00772264 |
| RHOB | ras homolog family member B | 0.00770242 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00768546 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00767688 |
| USP18 | ubiquitin specific peptidase 18 | 0.00766914 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00766108 |
| SFN | stratifin | 0.00763118 |
| VCAN | versican | 0.00762211 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.0076139 |
| C2 | complement component 2 | 0.00760821 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00759716 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00748158 |
| PLAU | plasminogen activator, urokinase | 0.00747839 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00747212 |
| KRT5 | keratin 5, type II | 0.00746302 |
| MXRA5 | matrix-remodelling associated 5 | 0.00744702 |
| TUFT1 | tuftelin 1 | 0.00744098 |
| RCAN1 | regulator of calcineurin 1 | 0.00739137 |
| PALLD | palladin, cytoskeletal associated protein | 0.00737855 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00737539 |
| KRT14 | keratin 14, type I | 0.00736828 |
| MVP | major vault protein | 0.00736352 |
| ZNF264 | zinc finger protein 264 | 0.00732511 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00729911 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.0072534 |
| ASRGL1 | asparaginase like 1 | 0.00724448 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00724367 |
| TRIM8 | tripartite motif containing 8 | 0.00724043 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00723815 |
| REXO2 | RNA exonuclease 2 | 0.0072364 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00721767 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00718879 |
| HNMT | histamine N-methyltransferase | 0.00717619 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00714396 |
| EMX2 | empty spiracles homeobox 2 | 0.00712912 |
| THBS1 | thrombospondin 1 | 0.00712077 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00708442 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00708249 |
| NCALD | neurocalcin delta | 0.00707807 |
| SERINC5 | serine incorporator 5 | 0.00707751 |
| MID1 | midline 1 | 0.00704079 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | 0.00702588 |
| MT1G | metallothionein 1G | 0.00701431 |
| MNT | MAX network transcriptional repressor | 0.00699524 |
| ATP10A | ATPase, class V, type 10A | 0.00697082 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00695869 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00695686 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00695174 |
| JMJD1C | jumonji domain containing 1C | 0.006946 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00692386 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00690464 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00688666 |
| SQSTM1 | sequestosome 1 | 0.00687065 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00687043 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00686903 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 | 0.00685716 |
| EDNRA | endothelin receptor type A | 0.00684197 |
| MRTFB | myocardin related transcription factor B | 0.00682998 |
| IER5 | immediate early response 5 | 0.0068128 |
| JAG1 | jagged 1 | 0.00679764 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00677955 |
| TSKU | tsukushi, small leucine rich proteoglycan | 0.00676725 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00676018 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00674522 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.00674482 |
| S100A11 | S100 calcium binding protein A11 | 0.00674084 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00672641 |
| EFNA1 | ephrin-A1 | 0.00672389 |
| MEIS1 | Meis homeobox 1 | 0.00671726 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0067166 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00671143 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00668591 |
| ABHD2 | abhydrolase domain containing 2 | 0.00666355 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00665726 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00665607 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00665433 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00665362 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00665166 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.00664103 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00660942 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00660638 |
| RRAGC | Ras-related GTP binding C | 0.00659629 |
| SYT1 | synaptotagmin I | 0.00659258 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00657039 |
| TPP1 | tripeptidyl peptidase I | 0.00655014 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00654169 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00653669 |
| MED13L | mediator complex subunit 13-like | 0.00652751 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00652417 |
| CD93 | CD93 molecule | 0.00652346 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00650619 |
| FMO1 | flavin containing monooxygenase 1 | 0.00649362 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00648809 |
| TOX3 | TOX high mobility group box family member 3 | 0.00647153 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00646451 |
| GGT1 | gamma-glutamyltransferase 1 | 0.00646378 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00646353 |
| DUSP3 | dual specificity phosphatase 3 | 0.00645015 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | 0.00644496 |
| SEC24A | SEC24 family member A | 0.00644065 |
| S100A2 | S100 calcium binding protein A2 | 0.00642555 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00641966 |
| SPRR2B | small proline-rich protein 2B | 0.00639956 |
| BGN | biglycan | 0.00639948 |
| LXN | latexin | 0.00639781 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00638822 |
| SPATA20 | spermatogenesis associated 20 | 0.0063863 |
| CTSL | cathepsin L | 0.00638568 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.0063852 |
| MAL | mal, T-cell differentiation protein | 0.00636734 |
| C5ORF15 | chromosome 5 open reading frame 15 | 0.00636601 |
| KLK10 | kallikrein-related peptidase 10 | 0.00636402 |
| TSPAN1 | tetraspanin 1 | 0.00636124 |
| S100A4 | S100 calcium binding protein A4 | 0.00635437 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00634853 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00634315 |
| PLK2 | polo-like kinase 2 | 0.00633167 |
| RETREG3 | reticulophagy regulator family member 3 | 0.00632144 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00631733 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0063171 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00631397 |
| SFXN3 | sideroflexin 3 | 0.00631262 |
| FAM107A | family with sequence similarity 107, member A | 0.00630892 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00630864 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00629907 |
| KMT5B | lysine methyltransferase 5B | 0.00629495 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00629148 |
| ZNF586 | zinc finger protein 586 | 0.00628787 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00628746 |
| TBX3 | T-box 3 | 0.00626526 |
| RHOF | ras homolog family member F (in filopodia) | 0.00626509 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00626261 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00623762 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00621107 |
| TRIM38 | tripartite motif containing 38 | 0.00620427 |
| ESR1 | estrogen receptor 1 | 0.00620427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0158215 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0135401 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0133033 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0126864 |
| ORC1 | origin recognition complex, subunit 1 | -0.0124389 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0123132 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.0121829 |
| OLFM4 | olfactomedin 4 | -0.0116225 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.011331 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0107148 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0103673 |
| HMGB2 | high mobility group box 2 | -0.0103079 |
| RAD51AP1 | RAD51 associated protein 1 | -0.0102924 |
| TFRC | transferrin receptor | -0.0100988 |
| OIP5 | Opa interacting protein 5 | -0.00988169 |
| CDCA3 | cell division cycle associated 3 | -0.00987117 |
| LMNB1 | lamin B1 | -0.00966811 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00961862 |
| FOXM1 | forkhead box M1 | -0.00953916 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00951405 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00949759 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00944444 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00923826 |
| LTF | lactotransferrin | -0.00910417 |
| MCM5 | minichromosome maintenance complex component 5 | -0.00899674 |
| FABP7 | fatty acid binding protein 7, brain | -0.00893731 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00891396 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00881868 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00880656 |
| RTN1 | reticulon 1 | -0.00880232 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00871208 |
| DEPDC1 | DEP domain containing 1 | -0.00870065 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00867624 |
| ACTB | actin, beta | -0.00850135 |
| CA2 | carbonic anhydrase II | -0.00849756 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00848822 |
| PHB2 | prohibitin 2 | -0.00847753 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00845463 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00845192 |
| SNX13 | sorting nexin 13 | -0.00843162 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00841707 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0084007 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00834633 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00824007 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00822115 |
| SHOX2 | short stature homeobox 2 | -0.00821629 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00820324 |
| GAL | galanin/GMAP prepropeptide | -0.00818606 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00812483 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00809168 |
| APOB | apolipoprotein B | -0.00804224 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00803384 |
| CDC45 | cell division cycle 45 | -0.00797655 |
| CHEK1 | checkpoint kinase 1 | -0.00794592 |
| PITX1 | paired-like homeodomain 1 | -0.00787631 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00785105 |
| MSH2 | mutS homolog 2 | -0.00783852 |
| EREG | epiregulin | -0.0078326 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00777745 |
| CCNA2 | cyclin A2 | -0.00766789 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00764449 |
| H1-10 | H1.10 linker histone | -0.00759581 |
| TNC | tenascin C | -0.00758336 |
| KIF20A | kinesin family member 20A | -0.00754473 |
| HMGN1 | high mobility group nucleosome binding domain 1 | -0.00749105 |
| CDC6 | cell division cycle 6 | -0.00743565 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00735812 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0073539 |
| KIF23 | kinesin family member 23 | -0.0073066 |
| PKP2 | plakophilin 2 | -0.00729522 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00729371 |
| TRMT5 | tRNA methyltransferase 5 | -0.00727573 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00727432 |
| KIF18A | kinesin family member 18A | -0.00726229 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.00723316 |
| KIF15 | kinesin family member 15 | -0.00722493 |
| MCM10 | minichromosome maintenance complex component 10 | -0.0071966 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00718734 |
| LUM | lumican | -0.007181 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.00714658 |
| DTWD1 | DTW domain containing 1 | -0.00710182 |
| LOX | lysyl oxidase | -0.00702193 |
| TMSB15A | thymosin beta 15a | -0.0069933 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00698293 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.0069745 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | -0.00694028 |
| INSM1 | insulinoma-associated 1 | -0.00692731 |
| YBX3 | Y box binding protein 3 | -0.00691813 |
| ART3 | ADP-ribosyltransferase 3 | -0.00687755 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00687293 |
| FBXO5 | F-box protein 5 | -0.00685271 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.00684767 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00683557 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00682612 |
| NCAPH | non-SMC condensin I complex, subunit H | -0.0068213 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00681143 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00680187 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.00678839 |
| APMAP | adipocyte plasma membrane associated protein | -0.00678695 |
| NDC80 | NDC80 kinetochore complex component | -0.00677409 |
| FOXD1 | forkhead box D1 | -0.00677045 |
| RPL10 | ribosomal protein L10 | -0.00676708 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00675748 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00675622 |
| NIT1 | nitrilase 1 | -0.00673605 |
| HHEX | hematopoietically expressed homeobox | -0.00672442 |
| EXO1 | exonuclease 1 | -0.00671856 |
| CALB2 | calbindin 2 | -0.00671574 |
| TMEM38B | transmembrane protein 38B | -0.00670317 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -0.00669301 |
| ZNF232 | zinc finger protein 232 | -0.00667221 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00666266 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00664776 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | -0.00663956 |
| DUT | deoxyuridine triphosphatase | -0.00662169 |
| TRIB3 | tribbles pseudokinase 3 | -0.00659716 |
| SET | SET nuclear proto-oncogene | -0.00656283 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa | -0.00655163 |
| SDC2 | syndecan 2 | -0.00653512 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.00653369 |
| IL7 | interleukin 7 | -0.00651648 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.00649823 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00649221 |
| YEATS4 | YEATS domain containing 4 | -0.00648709 |
| IPO5 | importin 5 | -0.00647895 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00647552 |
| EXOC5 | exocyst complex component 5 | -0.00647141 |
| DBF4 | DBF4 zinc finger | -0.00645213 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00643725 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00643424 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.00642911 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.00639881 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00638034 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00633673 |
| PCBP2 | poly(rC) binding protein 2 | -0.00632475 |
| NEK2 | NIMA-related kinase 2 | -0.00631917 |
| H2AX | H2A.X variant histone | -0.00629547 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00628042 |
| ADORA2B | adenosine A2b receptor | -0.00626274 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00624008 |
| PARPBP | PARP1 binding protein | -0.00622262 |
| E2F8 | E2F transcription factor 8 | -0.0062159 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00621523 |
| CDT1 | chromatin licensing and DNA replication factor 1 | -0.00621397 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.00621109 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00620225 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00619583 |
| PRR15L | proline rich 15-like | -0.00617232 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00616809 |
| SMC2 | structural maintenance of chromosomes 2 | -0.00615951 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.0061497 |
| HMGB1 | high mobility group box 1 | -0.00614726 |
| TXNL4B | thioredoxin-like 4B | -0.00613854 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -0.00613715 |
| FBXO11 | F-box protein 11 | -0.00612452 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0061225 |
| PON3 | paraoxonase 3 | -0.00611611 |
| CANX | calnexin | -0.00611557 |
| CA3 | carbonic anhydrase III | -0.00611187 |
| CENPE | centromere protein E, 312kDa | -0.00609614 |
| ISL1 | ISL LIM homeobox 1 | -0.00609341 |
| PMCH | pro-melanin-concentrating hormone | -0.00609329 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00609272 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00608603 |
| FOXE1 | forkhead box E1 | -0.00608102 |
| PIMREG | PICALM interacting mitotic regulator | -0.00608018 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00607237 |
| SPAG6 | sperm associated antigen 6 | -0.00605116 |
| E2F2 | E2F transcription factor 2 | -0.00604051 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0060369 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.00602761 |
| ACTL6A | actin-like 6A | -0.00602428 |
| C1ORF112 | chromosome 1 open reading frame 112 | -0.0060024 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | -0.00598732 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00598365 |
| CDC25C | cell division cycle 25C | -0.00597467 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00594645 |
| C17ORF75 | chromosome 17 open reading frame 75 | -0.00591984 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.00591594 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00590833 |
| MTAP | methylthioadenosine phosphorylase | -0.00590626 |
| TK1 | thymidine kinase 1, soluble | -0.00589625 |
| MEOX2 | mesenchyme homeobox 2 | -0.00588953 |
| FANCG | Fanconi anemia, complementation group G | -0.0058794 |
| MRPL9 | mitochondrial ribosomal protein L9 | -0.00586749 |
| MAGEA4 | melanoma antigen family A4 | -0.00586496 |
| DEK | DEK proto-oncogene | -0.00585941 |
| MNS1 | meiosis-specific nuclear structural 1 | -0.00584555 |
| SRP9 | signal recognition particle 9kDa | -0.00584325 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00583781 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00583215 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.00583195 |
| MKI67 | marker of proliferation Ki-67 | -0.0058288 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.00582688 |
| TPD52L1 | tumor protein D52-like 1 | -0.00582182 |
| HYOU1 | hypoxia up-regulated 1 | -0.00581965 |
| CD1E | CD1e molecule | -0.00580698 |
| TTK | TTK protein kinase | -0.0058036 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00580262 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -0.00580112 |
| DKC1 | dyskeratosis congenita 1, dyskerin | -0.00578572 |
| BORA | bora, aurora kinase A activator | -0.00578292 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00577952 |
| MEIS2 | Meis homeobox 2 | -0.00577603 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00577481 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00576498 |
| STMN2 | stathmin 2 | -0.00576206 |
| RAD21 | RAD21 homolog (S. pombe) | -0.00576019 |
| PLK4 | polo-like kinase 4 | -0.0057579 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.00575744 |
| ODAM | odontogenic, ameloblast asssociated | -0.00575658 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00575514 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00573437 |
| CDCA8 | cell division cycle associated 8 | -0.00573432 |
| CPOX | coproporphyrinogen oxidase | -0.0057312 |
| NUP160 | nucleoporin 160kDa | -0.00572788 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0057243 |
| CD164 | CD164 molecule, sialomucin | -0.00572297 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00572042 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -0.0057113 |
| CALCA | calcitonin-related polypeptide alpha | -0.0057092 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | -0.00570713 |
| TEAD4 | TEA domain family member 4 | -0.00569639 |
| PRKD3 | protein kinase D3 | -0.00569545 |
| ZNF804A | zinc finger protein 804A | -0.00568503 |
| MED28 | mediator complex subunit 28 | -0.00568106 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0056809 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00567626 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00567431 |
| CENPA | centromere protein A | -0.00567026 |
| L1CAM | L1 cell adhesion molecule | -0.00564802 |
| CENPU | centromere protein U | -0.00564711 |
| MYH1 | myosin, heavy chain 1, skeletal muscle, adult | -0.00564677 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0056457 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00563862 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.00562768 |
| KIF18B | kinesin family member 18B | -0.00562131 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00562119 |
| TRDN | triadin | -0.00562074 |
| THAP9-AS1 | THAP9 antisense RNA 1 | -0.00561958 |
| MAT2A | methionine adenosyltransferase II, alpha | -0.00561502 |
| MRPL36 | mitochondrial ribosomal protein L36 | -0.00560984 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00560856 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.00559577 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00557048 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00555679 |
| CENPQ | centromere protein Q | -0.00554547 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.00554246 |
| THOC1 | THO complex 1 | -0.00554083 |
| HIRA | histone cell cycle regulator | -0.00553315 |
