CDK8_knockdown_128_GSE30815 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30815
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Genes

600 genes differentially expressed following the CDK8_knockdown_128_GSE30815 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
BIRC5 baculoviral IAP repeat containing 5 3.9749
SEZ6L2 seizure related 6 homolog (mouse)-like 2 3.95174
HIST2H2AA4 histone cluster 2, H2aa4 3.89849
CIB1 calcium and integrin binding 1 (calmyrin) 3.62082
TMEM230 transmembrane protein 230 3.60525
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 3.60485
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 3.40148
HLA-E major histocompatibility complex, class I, E 3.27637
SEP15 15 kDa selenoprotein 3.21477
C16ORF95 chromosome 16 open reading frame 95 3.17111
CDK5 cyclin-dependent kinase 5 3.12659
TSPAN3 tetraspanin 3 3.04215
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 3.0181
EVA1B eva-1 homolog B (C. elegans) 2.98408
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.92021
SMYD2 SET and MYND domain containing 2 2.91695
WDR1 WD repeat domain 1 2.9162
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.90745
LXN latexin 2.89536
FAM173A family with sequence similarity 173, member A 2.89391
UBXN1 UBX domain protein 1 2.8904
SLC22A23 solute carrier family 22, member 23 2.84992
LINC00482 long intergenic non-protein coding RNA 482 2.83439
LOC100505938 uncharacterized LOC100505938 2.81995
IFITM2 interferon induced transmembrane protein 2 2.80844
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.79756
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 2.79662
GPBP1 GC-rich promoter binding protein 1 2.77803
FAM49B family with sequence similarity 49, member B 2.76795
SPIN2B spindlin family, member 2B 2.75926
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 2.75634
SKAP1 src kinase associated phosphoprotein 1 2.74701
ZNF219 zinc finger protein 219 2.74234
GSTK1 glutathione S-transferase kappa 1 2.73734
MAGEA12 melanoma antigen family A12 2.72052
ARL1 ADP-ribosylation factor-like 1 2.69838
SCAND1 SCAN domain containing 1 2.67159
RNF26 ring finger protein 26 2.65206
MAOA monoamine oxidase A 2.643
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.63622
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.62649
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 2.62401
ZDHHC7 zinc finger, DHHC-type containing 7 2.62186
C6ORF106 chromosome 6 open reading frame 106 2.61127
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.59483
FHL2 four and a half LIM domains 2 2.56201
SHISA4 shisa family member 4 2.50657
SFT2D1 SFT2 domain containing 1 2.49182
KRTCAP2 keratinocyte associated protein 2 2.47326
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 2.46793
HLA-J major histocompatibility complex, class I, J (pseudogene) 2.45911
ZNF746 zinc finger protein 746 2.45555
LAMP2 lysosomal-associated membrane protein 2 2.44503
GPC1 glypican 1 2.43663
TLR8 toll-like receptor 8 2.43596
NCKAP5L NCK-associated protein 5-like 2.38375
PUS3 pseudouridylate synthase 3 2.38239
FBRSL1 fibrosin-like 1 2.38114
DOCK1 dedicator of cytokinesis 1 2.37965
KIFAP3 kinesin-associated protein 3 2.37646
TMEM53 transmembrane protein 53 2.34434
FBXO33 F-box protein 33 2.31889
TMEM54 transmembrane protein 54 2.31855
MRPL53 mitochondrial ribosomal protein L53 2.31134
FANCE Fanconi anemia, complementation group E 2.30373
SARS2 seryl-tRNA synthetase 2, mitochondrial 2.29458
RELL2 RELT-like 2 2.2855
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 2.28505
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.27512
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.26898
FBXL19 F-box and leucine-rich repeat protein 19 2.26764
PCED1B PC-esterase domain containing 1B 2.2411
TALDO1 transaldolase 1 2.23961
ERBB2 erb-b2 receptor tyrosine kinase 2 2.22853
MAPKAP1 mitogen-activated protein kinase associated protein 1 2.22747
COL16A1 collagen, type XVI, alpha 1 2.2238
RPL34 ribosomal protein L34 2.21969
FYTTD1 forty-two-three domain containing 1 2.21915
TEAD3 TEA domain family member 3 2.21385
TP53I11 tumor protein p53 inducible protein 11 2.2114
TCEAL8 transcription elongation factor A (SII)-like 8 2.20057
ECHDC2 enoyl CoA hydratase domain containing 2 2.19123
AKR1C3 aldo-keto reductase family 1, member C3 2.19096
NPEPL1 aminopeptidase-like 1 2.19031
TBP TATA box binding protein 2.18855
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.1877
ZG16B zymogen granule protein 16B 2.1852
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 2.18215
ERCC5 excision repair cross-complementation group 5 2.1791
AURKAIP1 aurora kinase A interacting protein 1 2.1741
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.1617
ISOC1 isochorismatase domain containing 1 2.15661
YPEL5 yippee-like 5 (Drosophila) 2.15419
ACOT4 acyl-CoA thioesterase 4 2.15387
MFSD3 major facilitator superfamily domain containing 3 2.13515
VARS2 valyl-tRNA synthetase 2, mitochondrial 2.11935
ZBTB45 zinc finger and BTB domain containing 45 2.10989
DCTN3 dynactin 3 (p22) 2.10617
MAP2K4 mitogen-activated protein kinase kinase 4 2.10178
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.1004
MAGEA6 melanoma antigen family A6 2.09878
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2.09614
THAP3 THAP domain containing, apoptosis associated protein 3 2.09228
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 2.08956
IFI27L2 interferon, alpha-inducible protein 27-like 2 2.07282
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 2.07189
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 2.06749
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.06722
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 2.06545
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 2.05708
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 2.05301
SH3GL1 SH3-domain GRB2-like 1 2.04985
ZNF821 zinc finger protein 821 2.04877
D2HGDH D-2-hydroxyglutarate dehydrogenase 2.04132
ERCC1 excision repair cross-complementation group 1 2.03497
HLA-B major histocompatibility complex, class I, B 2.03296
TPBG trophoblast glycoprotein 2.03123
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 2.02692
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 2.02556
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 2.01022
HIGD2A HIG1 hypoxia inducible domain family, member 2A 2.0077
HLA-F major histocompatibility complex, class I, F 2.00763
TOB2P1 transducer of ERBB2, 2 pseudogene 1 1.99926
PRSS2 protease, serine, 2 (trypsin 2) 1.99374
TMEM175 transmembrane protein 175 1.99154
DNASE1L1 deoxyribonuclease I-like 1 1.98971
TMPRSS13 transmembrane protease, serine 13 1.98262
MICALL2 MICAL-like 2 1.97645
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.97514
SMIM7 small integral membrane protein 7 1.967
KAT5 K(lysine) acetyltransferase 5 1.9649
RGL2 ral guanine nucleotide dissociation stimulator-like 2 1.96461
RPTOR regulatory associated protein of MTOR, complex 1 1.96434
ADCK5 aarF domain containing kinase 5 1.96418
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1.96378
HLA-DMA major histocompatibility complex, class II, DM alpha 1.94518
SGSM3 small G protein signaling modulator 3 1.94431
C19ORF73 chromosome 19 open reading frame 73 1.93693
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 1.93069
EPS8L2 EPS8-like 2 1.92531
NTN4 netrin 4 1.92249
OCIAD2 OCIA domain containing 2 1.92129
ZHX1 zinc fingers and homeoboxes 1 1.90807
CAPNS1 calpain, small subunit 1 1.8986
C9ORF16 chromosome 9 open reading frame 16 1.89758
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1.89699
ZFAT zinc finger and AT hook domain containing 1.89364
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.88903
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 1.88833
CCNL2 cyclin L2 1.88506
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.87887
OVCA2 ovarian tumor suppressor candidate 2 1.87816
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.87419
PCDHGA8 protocadherin gamma subfamily A, 8 1.87017
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.86727
GOPC golgi-associated PDZ and coiled-coil motif containing 1.854
MRPS18A mitochondrial ribosomal protein S18A 1.85165
TUSC2 tumor suppressor candidate 2 1.84803
TBC1D10B TBC1 domain family, member 10B 1.83701
CYTH1 cytohesin 1 1.8338
ELAC1 elaC ribonuclease Z 1 1.8336
RHOD ras homolog family member D 1.82755
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 1.82623
SPATA20 spermatogenesis associated 20 1.8237
UNC45A unc-45 homolog A (C. elegans) 1.81686
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 1.80912
LRWD1 leucine-rich repeats and WD repeat domain containing 1 1.80516
RAB18 RAB18, member RAS oncogene family 1.80212
SH3BP2 SH3-domain binding protein 2 1.79627
LOC644189 acyl-CoA thioesterase 4 pseudogene 1.79011
FAM189B family with sequence similarity 189, member B 1.78442
STOML1 stomatin (EPB72)-like 1 1.78258
ZFPM1 zinc finger protein, FOG family member 1 1.77952
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.77615
STK11IP serine/threonine kinase 11 interacting protein 1.77524
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 1.77341
CHMP4A charged multivesicular body protein 4A 1.77079
CTSD cathepsin D 1.77035
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.76869
BCAS1 breast carcinoma amplified sequence 1 1.76403
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.76119
GHDC GH3 domain containing 1.75608
VEGFB vascular endothelial growth factor B 1.75554
DHRS7 dehydrogenase/reductase (SDR family) member 7 1.75537
APOE apolipoprotein E 1.75059
SUCO SUN domain containing ossification factor 1.74277
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.73684
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.73505
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.72932
MAP3K6 mitogen-activated protein kinase kinase kinase 6 1.72329
ERGIC3 ERGIC and golgi 3 1.72173
C19ORF25 chromosome 19 open reading frame 25 1.72062
POR P450 (cytochrome) oxidoreductase 1.7053
SMIM15 small integral membrane protein 15 1.69775
SCYL1 SCY1-like 1 (S. cerevisiae) 1.69237
TSC22D4 TSC22 domain family, member 4 1.69218
SCAF1 SR-related CTD-associated factor 1 1.67384
HOXB13 homeobox B13 1.67313
SMIM19 small integral membrane protein 19 1.67236
CCDC107 coiled-coil domain containing 107 1.6722
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.67013
PNKP polynucleotide kinase 3'-phosphatase 1.66619
DHRS11 dehydrogenase/reductase (SDR family) member 11 1.65728
TMEM136 transmembrane protein 136 1.65254
SNAPIN SNAP-associated protein 1.65202
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.65124
PLS3 plastin 3 1.64724
HLA-C major histocompatibility complex, class I, C 1.6469
SMAP1 small ArfGAP 1 1.63634
GLCCI1 glucocorticoid induced 1 1.63307
AHRR aryl-hydrocarbon receptor repressor 1.63154
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1.63123
SLC22A18 solute carrier family 22, member 18 1.62555
WSB1 WD repeat and SOCS box containing 1 1.62359
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.62272
ICAM2 intercellular adhesion molecule 2 1.62112
GP9 glycoprotein IX (platelet) 1.61682
ZNF575 zinc finger protein 575 1.61542
BANF1 barrier to autointegration factor 1 1.61323
CLN3 ceroid-lipofuscinosis, neuronal 3 1.6129
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 1.61237
RPL13 ribosomal protein L13 1.61219
BTBD1 BTB (POZ) domain containing 1 1.60969
IFRD2 interferon-related developmental regulator 2 1.60933
ZNF469 zinc finger protein 469 1.60761
CCDC102A coiled-coil domain containing 102A 1.60662
MDK midkine (neurite growth-promoting factor 2) 1.60402
S100A10 S100 calcium binding protein A10 1.60296
DAD1 defender against cell death 1 1.6016
MAP1S microtubule-associated protein 1S 1.60024
PPP1R35 protein phosphatase 1, regulatory subunit 35 1.59562
PXDC1 PX domain containing 1 1.5926
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 1.59258
PXMP4 peroxisomal membrane protein 4, 24kDa 1.5925
ADAT1 adenosine deaminase, tRNA-specific 1 1.59163
PRDX5 peroxiredoxin 5 1.5886
SLC44A4 solute carrier family 44, member 4 1.58675
AQP3 aquaporin 3 (Gill blood group) 1.58645
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.58435
CD79A CD79a molecule, immunoglobulin-associated alpha 1.58417
WDR11 WD repeat domain 11 1.58034
PARD6A par-6 family cell polarity regulator alpha 1.57923
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 1.57405
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.57397
NRBF2 nuclear receptor binding factor 2 1.56665
MVP major vault protein 1.56662
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 1.56487
WDR18 WD repeat domain 18 1.56045
TMEM238 transmembrane protein 238 1.55351
ZFAND6 zinc finger, AN1-type domain 6 1.54848
ITFG1 integrin alpha FG-GAP repeat containing 1 1.54751
ZNF444 zinc finger protein 444 1.54399
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1.53797
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.53209
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 1.52817
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.527
GOLGA8IP golgin A8 family, member I, pseudogene 1.52297
GBA glucosidase, beta, acid 1.52164
TRPM5 transient receptor potential cation channel, subfamily M, member 5 1.52087
ZNF579 zinc finger protein 579 1.51822
NUBP1 nucleotide binding protein 1 1.51749
PYGO2 pygopus family PHD finger 2 1.50877
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 1.5085
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.50657
CFL1P1 cofilin 1 (non-muscle) pseudogene 1 1.50267
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.50144
ELMO3 engulfment and cell motility 3 1.49906
RHBDD3 rhomboid domain containing 3 1.49847
SERGEF secretion regulating guanine nucleotide exchange factor 1.49621
MRPL27 mitochondrial ribosomal protein L27 1.49425
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 1.49394
RNF14 ring finger protein 14 1.49121
MSRB1 methionine sulfoxide reductase B1 1.4907
C16ORF93 chromosome 16 open reading frame 93 1.48751
TMEM55A transmembrane protein 55A 1.47749
MED15 mediator complex subunit 15 1.47628
IL4R interleukin 4 receptor 1.47052
SPAG7 sperm associated antigen 7 1.47021
CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 1.46883
PARD3 par-3 family cell polarity regulator 1.46552
LEPROTL1 leptin receptor overlapping transcript-like 1 1.46307
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.46259
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 1.46198
ANAPC5 anaphase promoting complex subunit 5 1.46012
HLA-H major histocompatibility complex, class I, H (pseudogene) 1.45678
TMEM9B TMEM9 domain family, member B 1.45652
SUSD3 sushi domain containing 3 1.45381
CSRP1 cysteine and glycine-rich protein 1 1.45316
HDLBP high density lipoprotein binding protein 1.45277
RABL6 RAB, member RAS oncogene family-like 6 1.45243
FBXL15 F-box and leucine-rich repeat protein 15 1.44932
MTIF3 mitochondrial translational initiation factor 3 1.44747
ANKRD46 ankyrin repeat domain 46 1.44559
PARVA parvin, alpha 1.44482
ARHGAP1 Rho GTPase activating protein 1 1.44472
SMIM22 small integral membrane protein 22 1.44234
LOC400684 uncharacterized LOC400684 1.43889
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.43664
DEF8 differentially expressed in FDCP 8 homolog (mouse) 1.43583
GLA galactosidase, alpha 1.43413

decreased expression

Symbol Name Standardized Value
RPL28 ribosomal protein L28 -4.28692
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.76314
NOLC1 nucleolar and coiled-body phosphoprotein 1 -3.69706
AUNIP aurora kinase A and ninein interacting protein -3.32765
REPIN1 replication initiator 1 -3.25364
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit -3.18951
TTC27 tetratricopeptide repeat domain 27 -3.13539
NOP56 NOP56 ribonucleoprotein -3.12663
MED30 mediator complex subunit 30 -3.07949
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) -3.02961
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 -2.97956
EXOSC1 exosome component 1 -2.90559
GTPBP3 GTP binding protein 3 (mitochondrial) -2.88775
DONSON downstream neighbor of SON -2.85737
PUSL1 pseudouridylate synthase-like 1 -2.84307
HIST1H3B histone cluster 1, H3b -2.84267
KPNB1 karyopherin (importin) beta 1 -2.82961
SREBF2 sterol regulatory element binding transcription factor 2 -2.8043
FAM122B family with sequence similarity 122B -2.80179
VEGFA vascular endothelial growth factor A -2.79527
OXSR1 oxidative stress responsive 1 -2.77155
NARF nuclear prelamin A recognition factor -2.73065
LIMK2 LIM domain kinase 2 -2.7003
CDK8 cyclin-dependent kinase 8 -2.69992
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 -2.66647
THOC3 THO complex 3 -2.63489
CNOT10 CCR4-NOT transcription complex, subunit 10 -2.63441
TPD52L2 tumor protein D52-like 2 -2.49707
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -2.49181
RAD54L RAD54-like (S. cerevisiae) -2.4914
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) -2.47904
EIF4A3 eukaryotic translation initiation factor 4A3 -2.44342
MZT1 mitotic spindle organizing protein 1 -2.36286
STX10 syntaxin 10 -2.35731
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 -2.35668
CHEK1 checkpoint kinase 1 -2.33895
PCNA proliferating cell nuclear antigen -2.33157
HIST1H1E histone cluster 1, H1e -2.32789
PAPOLA poly(A) polymerase alpha -2.29317
TRIM29 tripartite motif containing 29 -2.24694
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.23447
TMEM201 transmembrane protein 201 -2.22794
AK2 adenylate kinase 2 -2.2205
ALYREF Aly/REF export factor -2.19693
PARP2 poly (ADP-ribose) polymerase 2 -2.19446
CHML choroideremia-like (Rab escort protein 2) -2.18577
PPA1 pyrophosphatase (inorganic) 1 -2.18573
TESC tescalcin -2.17741
PPIA peptidylprolyl isomerase A (cyclophilin A) -2.17185
BUD31 BUD31 homolog (S. cerevisiae) -2.17023
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.16053
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.16021
CYR61 cysteine-rich, angiogenic inducer, 61 -2.13951
NOL7 nucleolar protein 7, 27kDa -2.12649
CMC2 C-x(9)-C motif containing 2 -2.12459
MRPL47 mitochondrial ribosomal protein L47 -2.1222
ASMTL acetylserotonin O-methyltransferase-like -2.11438
ENO1 enolase 1, (alpha) -2.10532
VRK2 vaccinia related kinase 2 -2.10194
ZCCHC10 zinc finger, CCHC domain containing 10 -2.10141
PTTG2 pituitary tumor-transforming 2 -2.10102
UBE2S ubiquitin-conjugating enzyme E2S -2.09434
AK4 adenylate kinase 4 -2.09253
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -2.07242
CDC45 cell division cycle 45 -2.07196
C1QBP complement component 1, q subcomponent binding protein -2.06852
CBX8 chromobox homolog 8 -2.06621
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.06233
LARP1B La ribonucleoprotein domain family, member 1B -2.05539
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.03994
GTF2A2 general transcription factor IIA, 2, 12kDa -2.03739
GCSHP3 glycine cleavage system protein H (aminomethyl carrier) pseudogene 3 -2.03666
TPM3 tropomyosin 3 -2.03195
FUNDC2P2 FUN14 domain containing 2 pseudogene 2 -2.02723
RNASEH2B ribonuclease H2, subunit B -2.02549
CENPW centromere protein W -2.01626
AATF apoptosis antagonizing transcription factor -2.01409
GLRX glutaredoxin (thioltransferase) -2.00909
CHEK2 checkpoint kinase 2 -2.0018
CENPN centromere protein N -2.00083
WRN Werner syndrome, RecQ helicase-like -1.99993
EIF3K eukaryotic translation initiation factor 3, subunit K -1.98986
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -1.98819
KIF15 kinesin family member 15 -1.9859
CDV3 CDV3 homolog (mouse) -1.98161
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -1.96898
MKNK1 MAP kinase interacting serine/threonine kinase 1 -1.96225
RXRA retinoid X receptor, alpha -1.94197
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -1.93553
METTL1 methyltransferase like 1 -1.92836
ZWILCH zwilch kinetochore protein -1.92764
AK6 adenylate kinase 6 -1.92741
MRPL42 mitochondrial ribosomal protein L42 -1.92383
GAS2 growth arrest-specific 2 -1.92093
MRPL52 mitochondrial ribosomal protein L52 -1.9147
C2CD2L C2CD2-like -1.91293
SNRPF small nuclear ribonucleoprotein polypeptide F -1.90606
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.90354
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -1.90316
COPS8 COP9 signalosome subunit 8 -1.89654
CENPE centromere protein E, 312kDa -1.89329
PBK PDZ binding kinase -1.88623
LINC00691 long intergenic non-protein coding RNA 691 -1.88314
TACC3 transforming, acidic coiled-coil containing protein 3 -1.8824
RSL1D1 ribosomal L1 domain containing 1 -1.88211
NAE1 NEDD8 activating enzyme E1 subunit 1 -1.87021
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -1.86998
GLRX5 glutaredoxin 5 -1.86463
LEAP2 liver expressed antimicrobial peptide 2 -1.86056
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -1.85388
CCDC50 coiled-coil domain containing 50 -1.84431
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 -1.83927
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -1.83882
HAUS1 HAUS augmin-like complex, subunit 1 -1.81401
MAP6D1 MAP6 domain containing 1 -1.81175
NUP155 nucleoporin 155kDa -1.81165
RTN3 reticulon 3 -1.80813
FAM86B2 family with sequence similarity 86, member B2 -1.79565
FAM86FP family with sequence similarity 86, member A pseudogene -1.79543
TMEM39A transmembrane protein 39A -1.79396
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.79169
CENPA centromere protein A -1.7874
HIST1H4E histone cluster 1, H4e -1.76654
KNSTRN kinetochore-localized astrin/SPAG5 binding protein -1.76583
F2 coagulation factor II (thrombin) -1.76204
SPRYD7 SPRY domain containing 7 -1.76118
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -1.75833
ING5 inhibitor of growth family, member 5 -1.75744
LRRC75B leucine rich repeat containing 75B -1.75475
AGO2 argonaute RISC catalytic component 2 -1.75458
JAGN1 jagunal homolog 1 (Drosophila) -1.74858
BARD1 BRCA1 associated RING domain 1 -1.74759
HAUS7 HAUS augmin-like complex, subunit 7 -1.73965
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -1.73899
ZNF324 zinc finger protein 324 -1.73824
FGFR1OP2 FGFR1 oncogene partner 2 -1.72376
FAM86EP family with sequence similarity 86, member A pseudogene -1.71858
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -1.71835
COX5A cytochrome c oxidase subunit Va -1.71511
TMEM97 transmembrane protein 97 -1.71428
C18ORF21 chromosome 18 open reading frame 21 -1.71178
HSPA4 heat shock 70kDa protein 4 -1.69021
SRSF11 serine/arginine-rich splicing factor 11 -1.68477
GMNN geminin, DNA replication inhibitor -1.68312
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -1.67733
LOC100133920 uncharacterized LOC100133920 -1.67732
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -1.67534
SELK selenoprotein K -1.67253
CHAF1A chromatin assembly factor 1, subunit A (p150) -1.66778
HYPK huntingtin interacting protein K -1.66763
ARHGAP11A Rho GTPase activating protein 11A -1.66376
REXO2 RNA exonuclease 2 -1.66334
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B -1.6623
ATRIP ATR interacting protein -1.66147
WDR3 WD repeat domain 3 -1.65457
TPM4 tropomyosin 4 -1.64448
TTC4 tetratricopeptide repeat domain 4 -1.64075
KIAA0020 KIAA0020 -1.63592
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -1.63564
TSN translin -1.63506
C12ORF45 chromosome 12 open reading frame 45 -1.63487
TOR1AIP1 torsin A interacting protein 1 -1.62548
DHODH dihydroorotate dehydrogenase (quinone) -1.6215
EZR ezrin -1.61714
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -1.61301
LYAR Ly1 antibody reactive -1.61204
EAF2 ELL associated factor 2 -1.61136
ZPR1 ZPR1 zinc finger -1.60853
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -1.60749
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 -1.607
IQCB1 IQ motif containing B1 -1.59874
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -1.59376
GRPEL2 GrpE-like 2, mitochondrial (E. coli) -1.59315
ZDHHC16 zinc finger, DHHC-type containing 16 -1.59238
TOB2 transducer of ERBB2, 2 -1.58441
PPARA peroxisome proliferator-activated receptor alpha -1.58138
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -1.57127
ZNF271P zinc finger protein 271, pseudogene -1.5705
RPS27 ribosomal protein S27 -1.5678
PPP4R2 protein phosphatase 4, regulatory subunit 2 -1.5641
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.56284
MYO5B myosin VB -1.55598
CENPO centromere protein O -1.55181
NASP nuclear autoantigenic sperm protein (histone-binding) -1.55084
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -1.54784
BTF3P11 basic transcription factor 3 pseudogene 11 -1.54531
ZSCAN20 zinc finger and SCAN domain containing 20 -1.54488
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.54334
KIFC1 kinesin family member C1 -1.54291
CLNS1A chloride channel, nucleotide-sensitive, 1A -1.5388
CCNA2 cyclin A2 -1.53764
PC pyruvate carboxylase -1.53709
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 -1.53656
MUC8 mucin 8 -1.53602
CCDC58 coiled-coil domain containing 58 -1.5356
PLSCR1 phospholipid scramblase 1 -1.5244
MED27 mediator complex subunit 27 -1.51335
WDR75 WD repeat domain 75 -1.50899
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -1.50766
MRPL14 mitochondrial ribosomal protein L14 -1.50357
MRPL12 mitochondrial ribosomal protein L12 -1.50084
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) -1.49804
SMC3 structural maintenance of chromosomes 3 -1.49711
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -1.49337
DHRS4 dehydrogenase/reductase (SDR family) member 4 -1.49275
POC1B POC1 centriolar protein B -1.49235
PTMA prothymosin, alpha -1.49048
ANAPC10 anaphase promoting complex subunit 10 -1.48836
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -1.48699
SUCLG1 succinate-CoA ligase, alpha subunit -1.48216
PUS1 pseudouridylate synthase 1 -1.48051
VDAC3 voltage-dependent anion channel 3 -1.47972
SRXN1 sulfiredoxin 1 -1.47936
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -1.47419
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -1.47389
RPS27L ribosomal protein S27-like -1.46752
GZMM granzyme M (lymphocyte met-ase 1) -1.46698
WDR77 WD repeat domain 77 -1.46587
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -1.46236
C1ORF109 chromosome 1 open reading frame 109 -1.4596
TNPO1 transportin 1 -1.45958
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.45781
UBE2F ubiquitin-conjugating enzyme E2F (putative) -1.45678
NUP133 nucleoporin 133kDa -1.44822
KIF2A kinesin heavy chain member 2A -1.44679
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -1.44092
ACOT7 acyl-CoA thioesterase 7 -1.43976
PEAR1 platelet endothelial aggregation receptor 1 -1.43485
PREB prolactin regulatory element binding -1.4342
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.43418
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -1.4328
C1ORF74 chromosome 1 open reading frame 74 -1.43174
PRPF18 pre-mRNA processing factor 18 -1.43149
NXT1 nuclear transport factor 2-like export factor 1 -1.43132
FOPNL FGFR1OP N-terminal like -1.42687
KARS lysyl-tRNA synthetase -1.42647
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.42355
TMEM14B transmembrane protein 14B -1.42202
TBC1D4 TBC1 domain family, member 4 -1.41737
ZNF330 zinc finger protein 330 -1.41494
FANCC Fanconi anemia, complementation group C -1.41315
UBE2B ubiquitin-conjugating enzyme E2B -1.41132
MRPL17 mitochondrial ribosomal protein L17 -1.40858
MRPL19 mitochondrial ribosomal protein L19 -1.40723
MRPL22 mitochondrial ribosomal protein L22 -1.40647
MCM3 minichromosome maintenance complex component 3 -1.40566
LAPTM4B lysosomal protein transmembrane 4 beta -1.40296
RPAP3 RNA polymerase II associated protein 3 -1.40051
BOP1 block of proliferation 1 -1.39843
SPATS2L spermatogenesis associated, serine-rich 2-like -1.39629
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -1.39438
CCDC59 coiled-coil domain containing 59 -1.39289
SPOP speckle-type POZ protein -1.39126
CDR2L cerebellar degeneration-related protein 2-like -1.38843
ALG10 ALG10, alpha-1,2-glucosyltransferase -1.3876
NUF2 NUF2, NDC80 kinetochore complex component -1.37564
TK1 thymidine kinase 1, soluble -1.37358
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) -1.37307
POLR1E polymerase (RNA) I polypeptide E, 53kDa -1.36804
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -1.36685
CEP85 centrosomal protein 85kDa -1.36655
COL11A2 collagen, type XI, alpha 2 -1.35887
TOR1B torsin family 1, member B (torsin B) -1.35741
SKA2 spindle and kinetochore associated complex subunit 2 -1.35686
HIST1H1D histone cluster 1, H1d -1.35226
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -1.34963
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa -1.34932
SPC25 SPC25, NDC80 kinetochore complex component -1.34249
TXNDC17 thioredoxin domain containing 17 -1.34188
C4BPA complement component 4 binding protein, alpha -1.34015
MED10 mediator complex subunit 10 -1.33994
LPCAT3 lysophosphatidylcholine acyltransferase 3 -1.33982
PRPF38B pre-mRNA processing factor 38B -1.33974
MYLIP myosin regulatory light chain interacting protein -1.33627
UBE2T ubiquitin-conjugating enzyme E2T -1.33512
TPI1P2 triosephosphate isomerase 1 pseudogene 2 -1.3338
RPS2 ribosomal protein S2 -1.33327
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -1.33294
MRPL2 mitochondrial ribosomal protein L2 -1.33053
BIN1 bridging integrator 1 -1.32673
PDS5B PDS5 cohesin associated factor B -1.32487
MYBBP1A MYB binding protein (P160) 1a -1.32464
TPP2 tripeptidyl peptidase II -1.32417
GABPB1 GA binding protein transcription factor, beta subunit 1 -1.32223
EXOSC7 exosome component 7 -1.32103
ZCCHC14 zinc finger, CCHC domain containing 14 -1.31746
SMC4 structural maintenance of chromosomes 4 -1.31486
CTSC cathepsin C -1.31273
PPP1R8 protein phosphatase 1, regulatory subunit 8 -1.31215
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -1.30933
NOP2 NOP2 nucleolar protein -1.30915
MOCOS molybdenum cofactor sulfurase -1.30754
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -1.30434
PUM2 pumilio RNA-binding family member 2 -1.30264
FKBP1A FK506 binding protein 1A, 12kDa -1.3013
RCC1 regulator of chromosome condensation 1 -1.29704
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -1.29625
ING2 inhibitor of growth family, member 2 -1.29619
SLC25A41 solute carrier family 25, member 41 -1.29408
FAM64A family with sequence similarity 64, member A -1.29367