CDK8_knockdown_129_GSE30816 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30816
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Genes

600 genes differentially expressed following the CDK8_knockdown_129_GSE30816 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
PRRC2A proline-rich coiled-coil 2A 4.14792
MID1IP1 MID1 interacting protein 1 3.87499
TMEM55A transmembrane protein 55A 3.86047
TTYH3 tweety family member 3 3.73754
FANCC Fanconi anemia, complementation group C 3.52681
DGKZ diacylglycerol kinase, zeta 3.35321
LSR lipolysis stimulated lipoprotein receptor 2.98349
NBEA neurobeachin 2.94248
E2F5 E2F transcription factor 5, p130-binding 2.93574
BBC3 BCL2 binding component 3 2.8859
CNIH2 cornichon family AMPA receptor auxiliary protein 2 2.85312
MXD3 MAX dimerization protein 3 2.82683
DLG3 discs, large homolog 3 (Drosophila) 2.81492
ACSL4 acyl-CoA synthetase long-chain family member 4 2.8098
SKAP2 src kinase associated phosphoprotein 2 2.78552
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 2.76735
GPM6B glycoprotein M6B 2.76236
TUBA1A tubulin, alpha 1a 2.7302
C9ORF40 chromosome 9 open reading frame 40 2.59668
ZNF687 zinc finger protein 687 2.5778
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.56389
ATF5 activating transcription factor 5 2.54356
STRAP serine/threonine kinase receptor associated protein 2.54117
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.5345
LEF1 lymphoid enhancer-binding factor 1 2.53345
NCAN neurocan 2.52197
ADGRL2 adhesion G protein-coupled receptor L2 2.51142
RPL14 ribosomal protein L14 2.48586
C15ORF61 chromosome 15 open reading frame 61 2.48049
CNKSR3 CNKSR family member 3 2.44539
SLC38A1 solute carrier family 38, member 1 2.39546
STAG2 stromal antigen 2 2.38591
B9D1 B9 protein domain 1 2.3817
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.36669
LZTS2 leucine zipper, putative tumor suppressor 2 2.35079
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 2.31673
NCEH1 neutral cholesterol ester hydrolase 1 2.30185
EPHA2 EPH receptor A2 2.29694
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.26884
SERTAD3 SERTA domain containing 3 2.25226
FAM98A family with sequence similarity 98, member A 2.25034
ARHGAP35 Rho GTPase activating protein 35 2.24637
SBF1 SET binding factor 1 2.24298
CEP131 centrosomal protein 131kDa 2.23558
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.23538
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 2.23327
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 2.22648
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 2.22474
PYCR2 pyrroline-5-carboxylate reductase family, member 2 2.21433
CIART circadian associated repressor of transcription 2.1757
NAAA N-acylethanolamine acid amidase 2.16603
BAHCC1 BAH domain and coiled-coil containing 1 2.16219
NOTCH2 notch 2 2.16156
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.15194
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 2.144
SQLE squalene epoxidase 2.13287
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.12304
MSRA methionine sulfoxide reductase A 2.11853
PCBP4 poly(rC) binding protein 4 2.10302
SPC24 SPC24, NDC80 kinetochore complex component 2.09915
HBP1 HMG-box transcription factor 1 2.09505
STRBP spermatid perinuclear RNA binding protein 2.09361
GADD45A growth arrest and DNA-damage-inducible, alpha 2.06303
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 2.03565
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.0352
UBE3B ubiquitin protein ligase E3B 2.02705
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 2.02632
ARMCX1 armadillo repeat containing, X-linked 1 2.02442
GEMIN5 gem (nuclear organelle) associated protein 5 2.02234
ARHGAP4 Rho GTPase activating protein 4 2.01318
C16ORF52 chromosome 16 open reading frame 52 2.00761
IDNK idnK, gluconokinase homolog (E. coli) 1.99303
IGSF10 immunoglobulin superfamily, member 10 1.99151
C16ORF58 chromosome 16 open reading frame 58 1.98768
MTA1 metastasis associated 1 1.98545
LBR lamin B receptor 1.97181
THOC6 THO complex 6 1.96897
CUEDC2 CUE domain containing 2 1.9611
SP8 Sp8 transcription factor 1.95991
SAP25 Sin3A-associated protein, 25kDa 1.95665
L2HGDH L-2-hydroxyglutarate dehydrogenase 1.95265
ARMC5 armadillo repeat containing 5 1.94549
INIP INTS3 and NABP interacting protein 1.93496
AIP aryl hydrocarbon receptor interacting protein 1.93332
ZNF627 zinc finger protein 627 1.93096
RMDN1 regulator of microtubule dynamics 1 1.93062
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 1.92056
GSTP1 glutathione S-transferase pi 1 1.91259
MNT MAX network transcriptional repressor 1.91168
GINS3 GINS complex subunit 3 (Psf3 homolog) 1.90498
FRMD4B FERM domain containing 4B 1.90015
ARMCX3 armadillo repeat containing, X-linked 3 1.89024
NT5DC2 5'-nucleotidase domain containing 2 1.88788
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.88358
TNRC6C trinucleotide repeat containing 6C 1.87155
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 1.86936
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.86468
MED25 mediator complex subunit 25 1.8535
RENBP renin binding protein 1.84261
SLC30A9 solute carrier family 30 (zinc transporter), member 9 1.83069
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 1.80232
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.79637
ZEB1 zinc finger E-box binding homeobox 1 1.78733
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1.78608
PLK3 polo-like kinase 3 1.78379
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 1.77768
RCE1 Ras converting CAAX endopeptidase 1 1.77741
STYX serine/threonine/tyrosine interacting protein 1.77655
STK39 serine threonine kinase 39 1.77545
TYMP thymidine phosphorylase 1.77377
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.77344
ZNF644 zinc finger protein 644 1.77021
LRRK2 leucine-rich repeat kinase 2 1.76526
HSF1 heat shock transcription factor 1 1.7608
KPTN kaptin (actin binding protein) 1.75907
JADE2 jade family PHD finger 2 1.7413
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.72531
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.71377
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.7124
COPE coatomer protein complex, subunit epsilon 1.71089
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.7049
DCHS1 dachsous cadherin-related 1 1.70372
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.7032
FAM173A family with sequence similarity 173, member A 1.69838
WBP5 WW domain binding protein 5 1.69402
WT1 Wilms tumor 1 1.69255
TMEM42 transmembrane protein 42 1.69047
WDR83OS WD repeat domain 83 opposite strand 1.69012
TMEM214 transmembrane protein 214 1.6879
HUNK hormonally up-regulated Neu-associated kinase 1.68693
MON2 MON2 homolog (S. cerevisiae) 1.68421
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.68383
C4ORF26 chromosome 4 open reading frame 26 1.68206
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.68202
LRRC49 leucine rich repeat containing 49 1.67736
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.67729
REEP3 receptor accessory protein 3 1.67639
UBE2R2 ubiquitin-conjugating enzyme E2R 2 1.67278
GPAA1 glycosylphosphatidylinositol anchor attachment 1 1.66996
CCDC12 coiled-coil domain containing 12 1.66572
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 1.66306
KIAA0101 KIAA0101 1.65737
VWA8 von Willebrand factor A domain containing 8 1.65526
C14ORF142 chromosome 14 open reading frame 142 1.65449
MAPK11 mitogen-activated protein kinase 11 1.65439
PRMT3 protein arginine methyltransferase 3 1.64843
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 1.64789
RPL27A ribosomal protein L27a 1.64602
SNTA1 syntrophin, alpha 1 1.64361
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.64193
NEURL4 neuralized E3 ubiquitin protein ligase 4 1.62911
MINA MYC induced nuclear antigen 1.62664
ZNF565 zinc finger protein 565 1.62647
C11ORF68 chromosome 11 open reading frame 68 1.62319
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 1.61884
TACC1 transforming, acidic coiled-coil containing protein 1 1.61821
TMEM159 transmembrane protein 159 1.61678
LIMD2 LIM domain containing 2 1.6151
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 1.61418
VEPH1 ventricular zone expressed PH domain-containing 1 1.60974
SERTAD2 SERTA domain containing 2 1.59795
EMC10 ER membrane protein complex subunit 10 1.59635
CORO1B coronin, actin binding protein, 1B 1.59616
BTG3 BTG family, member 3 1.57936
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 1.57649
CHD9 chromodomain helicase DNA binding protein 9 1.57526
DHPS deoxyhypusine synthase 1.57468
ZC2HC1A zinc finger, C2HC-type containing 1A 1.57228
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 1.57201
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.56287
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 1.5537
SIK3 SIK family kinase 3 1.55176
MTFP1 mitochondrial fission process 1 1.5491
SWAP70 SWAP switching B-cell complex 70kDa subunit 1.54299
VARS2 valyl-tRNA synthetase 2, mitochondrial 1.54037
TFRC transferrin receptor 1.53801
CLIC4 chloride intracellular channel 4 1.53764
FADS2 fatty acid desaturase 2 1.53272
FYCO1 FYVE and coiled-coil domain containing 1 1.53069
SGPP2 sphingosine-1-phosphate phosphatase 2 1.52609
USP28 ubiquitin specific peptidase 28 1.52542
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.52023
LAPTM4A lysosomal protein transmembrane 4 alpha 1.5192
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.51476
VEGFB vascular endothelial growth factor B 1.51469
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 1.51414
JTB jumping translocation breakpoint 1.50995
PDE1B phosphodiesterase 1B, calmodulin-dependent 1.50684
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 1.50529
TMEM43 transmembrane protein 43 1.50309
DROSHA drosha, ribonuclease type III 1.50232
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 1.50195
PNPLA6 patatin-like phospholipase domain containing 6 1.50184
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 1.49317
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.49304
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 1.48947
CNPY2 canopy FGF signaling regulator 2 1.48888
ZNF496 zinc finger protein 496 1.48656
PFKL phosphofructokinase, liver 1.48389
FRMD8 FERM domain containing 8 1.48362
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.47325
VRK3 vaccinia related kinase 3 1.47058
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.47043
DSG3 desmoglein 3 1.46338
KIAA1147 KIAA1147 1.46295
CRLS1 cardiolipin synthase 1 1.46035
RHBDL3 rhomboid, veinlet-like 3 (Drosophila) 1.45849
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 1.458
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1 1.45707
PRKX protein kinase, X-linked 1.45547
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 1.44423
DPH3 diphthamide biosynthesis 3 1.44408
PRUNE prune exopolyphosphatase 1.444
MAU2 MAU2 sister chromatid cohesion factor 1.44263
PISD phosphatidylserine decarboxylase 1.44164
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.44082
CCND2 cyclin D2 1.43914
BCAR3 breast cancer anti-estrogen resistance 3 1.43584
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 1.43225
TESK2 testis-specific kinase 2 1.43216
TOP2B topoisomerase (DNA) II beta 180kDa 1.43109
MYEF2 myelin expression factor 2 1.42874
HIP1R huntingtin interacting protein 1 related 1.42617
SHH sonic hedgehog 1.41902
MEST mesoderm specific transcript 1.41672
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 1.4135
PITRM1 pitrilysin metallopeptidase 1 1.41302
HCCS holocytochrome c synthase 1.41155
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 1.40692
OR51S1 olfactory receptor, family 51, subfamily S, member 1 1.40394
LRP12 low density lipoprotein receptor-related protein 12 1.40364
KLF10 Kruppel-like factor 10 1.40201
SLC22A17 solute carrier family 22, member 17 1.4017
VLDLR very low density lipoprotein receptor 1.40084
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.39883
PITX3 paired-like homeodomain 3 1.39664
VWA5A von Willebrand factor A domain containing 5A 1.39403
PLIN3 perilipin 3 1.39307
CLCN3 chloride channel, voltage-sensitive 3 1.39039
CTF1 cardiotrophin 1 1.38998
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.38852
ATP13A1 ATPase type 13A1 1.38554
DPYSL3 dihydropyrimidinase-like 3 1.38038
NR6A1 nuclear receptor subfamily 6, group A, member 1 1.3803
GSTM5 glutathione S-transferase mu 5 1.37997
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 1.37957
FBXL16 F-box and leucine-rich repeat protein 16 1.37935
AGO1 argonaute RISC catalytic component 1 1.37058
SP4 Sp4 transcription factor 1.37031
CSNK1G2 casein kinase 1, gamma 2 1.36354
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.35997
UBE3C ubiquitin protein ligase E3C 1.3586
TUBB tubulin, beta class I 1.35859
KMT2A lysine (K)-specific methyltransferase 2A 1.3555
TRIO trio Rho guanine nucleotide exchange factor 1.35531
DHCR7 7-dehydrocholesterol reductase 1.35254
ARFIP2 ADP-ribosylation factor interacting protein 2 1.35158
SIL1 SIL1 nucleotide exchange factor 1.35137
FXR1 fragile X mental retardation, autosomal homolog 1 1.35064
IP6K1 inositol hexakisphosphate kinase 1 1.35023
USP44 ubiquitin specific peptidase 44 1.34922
TMEM222 transmembrane protein 222 1.34736
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 1.34704
MAT2B methionine adenosyltransferase II, beta 1.34695
THBS3 thrombospondin 3 1.3467
UXT ubiquitously-expressed, prefoldin-like chaperone 1.3467
SREBF2 sterol regulatory element binding transcription factor 2 1.34654
NABP2 nucleic acid binding protein 2 1.34627
ZNF704 zinc finger protein 704 1.34243
ENDOV endonuclease V 1.3419
HSPA13 heat shock protein 70kDa family, member 13 1.33834
ARPP19 cAMP-regulated phosphoprotein, 19kDa 1.33354
TDO2 tryptophan 2,3-dioxygenase 1.3286
SCO1 SCO1 cytochrome c oxidase assembly protein 1.32452
SMAD4 SMAD family member 4 1.32367
MAGED1 melanoma antigen family D1 1.32327
PCSK9 proprotein convertase subtilisin/kexin type 9 1.32033
CCDC136 coiled-coil domain containing 136 1.31799
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.31792
PFKP phosphofructokinase, platelet 1.31641
GNPAT glyceronephosphate O-acyltransferase 1.3153
CCDC132 coiled-coil domain containing 132 1.31351
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 1.31339
TFE3 transcription factor binding to IGHM enhancer 3 1.31007
PKM pyruvate kinase, muscle 1.30976
DTX4 deltex 4, E3 ubiquitin ligase 1.30828
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.30739
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.30462
PLEKHA5 pleckstrin homology domain containing, family A member 5 1.30382
FRMD5 FERM domain containing 5 1.29821
ANKRD13B ankyrin repeat domain 13B 1.29761
HACD2 3-hydroxyacyl-CoA dehydratase 2 1.29721
EEF2 eukaryotic translation elongation factor 2 1.2952
EPC2 enhancer of polycomb homolog 2 (Drosophila) 1.29476
REPIN1 replication initiator 1 1.29459
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 1.29241
GMPS guanine monphosphate synthase 1.29125
SORT1 sortilin 1 1.28526
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 1.2847
GBP2 guanylate binding protein 2, interferon-inducible 1.28275

decreased expression

Symbol Name Standardized Value
BMP4 bone morphogenetic protein 4 -4.32673
HPS6 Hermansky-Pudlak syndrome 6 -4.01722
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -3.91586
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.45347
PROCR protein C receptor, endothelial -3.3605
ZBTB32 zinc finger and BTB domain containing 32 -3.30992
PLAC8 placenta-specific 8 -3.29896
NR4A1 nuclear receptor subfamily 4, group A, member 1 -3.23193
AK6 adenylate kinase 6 -3.12856
GSN gelsolin -3.09172
DERL1 derlin 1 -2.96151
TTC1 tetratricopeptide repeat domain 1 -2.88349
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -2.84015
INHBB inhibin, beta B -2.8346
SPAST spastin -2.82027
C17ORF62 chromosome 17 open reading frame 62 -2.81949
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) -2.81946
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -2.80164
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.78887
TEX264 testis expressed 264 -2.78649
WTIP Wilms tumor 1 interacting protein -2.78151
COPS6 COP9 signalosome subunit 6 -2.73847
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -2.72247
CASZ1 castor zinc finger 1 -2.72155
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.67969
MRPL36 mitochondrial ribosomal protein L36 -2.6778
TRAPPC1 trafficking protein particle complex 1 -2.66803
MRS2 MRS2 magnesium transporter -2.6437
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -2.62121
UCK2 uridine-cytidine kinase 2 -2.62033
TAGLN transgelin -2.61416
FAM118B family with sequence similarity 118, member B -2.57372
MYL12B myosin, light chain 12B, regulatory -2.55697
PROS1 protein S (alpha) -2.55302
TXNDC17 thioredoxin domain containing 17 -2.5428
RBMS1 RNA binding motif, single stranded interacting protein 1 -2.53094
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -2.52359
C12ORF45 chromosome 12 open reading frame 45 -2.52032
GSKIP GSK3B interacting protein -2.48759
RPAP2 RNA polymerase II associated protein 2 -2.46412
ITPK1 inositol-tetrakisphosphate 1-kinase -2.46293
TMEM19 transmembrane protein 19 -2.45811
SEC24B SEC24 family member B -2.4507
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 -2.36765
USP16 ubiquitin specific peptidase 16 -2.36255
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 -2.32466
CIR1 corepressor interacting with RBPJ, 1 -2.31032
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.29061
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.26462
SDAD1 SDA1 domain containing 1 -2.26309
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.26228
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.2457
CISD3 CDGSH iron sulfur domain 3 -2.23012
ULK1 unc-51 like autophagy activating kinase 1 -2.22987
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18 -2.22769
C1ORF174 chromosome 1 open reading frame 174 -2.21891
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha -2.21538
HBEGF heparin-binding EGF-like growth factor -2.21203
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -2.21192
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa -2.209
SWI5 SWI5 recombination repair homolog (yeast) -2.20277
CDIP1 cell death-inducing p53 target 1 -2.19622
RBM28 RNA binding motif protein 28 -2.18506
U2SURP U2 snRNP-associated SURP domain containing -2.18033
BVES blood vessel epicardial substance -2.15504
ZFP69 ZFP69 zinc finger protein -2.15462
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -2.15228
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -2.14644
SAMD11 sterile alpha motif domain containing 11 -2.1451
MRPS6 mitochondrial ribosomal protein S6 -2.14128
ZCCHC17 zinc finger, CCHC domain containing 17 -2.13119
MRPL43 mitochondrial ribosomal protein L43 -2.12576
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -2.11001
ZNF205 zinc finger protein 205 -2.09919
CEP104 centrosomal protein 104kDa -2.08519
PDGFA platelet-derived growth factor alpha polypeptide -2.08279
BCL6 B-cell CLL/lymphoma 6 -2.07769
TSPAN31 tetraspanin 31 -2.07323
GRB7 growth factor receptor-bound protein 7 -2.06453
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -2.06395
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -2.05461
PPAT phosphoribosyl pyrophosphate amidotransferase -2.05313
CYB561A3 cytochrome b561 family, member A3 -2.04929
TRNP1 TMF1-regulated nuclear protein 1 -2.04415
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -2.0383
PTBP3 polypyrimidine tract binding protein 3 -2.03803
LGALS1 lectin, galactoside-binding, soluble, 1 -2.03765
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -2.03749
DET1 de-etiolated homolog 1 (Arabidopsis) -2.02833
IKBIP IKBKB interacting protein -2.01915
PDZD3 PDZ domain containing 3 -2.01914
ETV4 ets variant 4 -2.01709
S100A10 S100 calcium binding protein A10 -2.0165
AGBL3 ATP/GTP binding protein-like 3 -2.01167
HSPE1 heat shock 10kDa protein 1 -2.00807
SH3BP1 SH3-domain binding protein 1 -2.00664
DUSP12 dual specificity phosphatase 12 -2.00202
TUFT1 tuftelin 1 -1.99118
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -1.9899
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -1.9817
MFAP1 microfibrillar-associated protein 1 -1.96904
AMACR alpha-methylacyl-CoA racemase -1.96679
PPP1R15B protein phosphatase 1, regulatory subunit 15B -1.95442
C2ORF50 chromosome 2 open reading frame 50 -1.95367
PLCD1 phospholipase C, delta 1 -1.95201
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -1.94693
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.94234
RFXANK regulatory factor X-associated ankyrin-containing protein -1.92912
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -1.92795
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.92469
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -1.91754
MUT methylmalonyl CoA mutase -1.91709
ASCL1 achaete-scute family bHLH transcription factor 1 -1.9163
HDLBP high density lipoprotein binding protein -1.91385
SNRNP48 small nuclear ribonucleoprotein 48kDa (U11/U12) -1.91271
CDCA3 cell division cycle associated 3 -1.90565
MPPE1 metallophosphoesterase 1 -1.90513
GJB3 gap junction protein, beta 3, 31kDa -1.90462
ESRP2 epithelial splicing regulatory protein 2 -1.89167
OLA1 Obg-like ATPase 1 -1.89126
TSPAN1 tetraspanin 1 -1.88016
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -1.87578
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -1.87425
MRPL45 mitochondrial ribosomal protein L45 -1.87413
CRTAP cartilage associated protein -1.87394
STK35 serine/threonine kinase 35 -1.87394
BUD13 BUD13 homolog (S. cerevisiae) -1.87032
TCTEX1D1 Tctex1 domain containing 1 -1.86587
CSRNP2 cysteine-serine-rich nuclear protein 2 -1.86257
TCF25 transcription factor 25 (basic helix-loop-helix) -1.85064
WDR12 WD repeat domain 12 -1.8505
MRPS26 mitochondrial ribosomal protein S26 -1.8481
MRPL49 mitochondrial ribosomal protein L49 -1.84422
FAM207A family with sequence similarity 207, member A -1.84213
FBXO34 F-box protein 34 -1.84063
CCNF cyclin F -1.83888
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.83611
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -1.83415
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa -1.83381
FRG1 FSHD region gene 1 -1.83321
HIST1H2BI histone cluster 1, H2bi -1.82583
NFS1 NFS1 cysteine desulfurase -1.82503
CCDC53 coiled-coil domain containing 53 -1.81653
OR5K3 olfactory receptor, family 5, subfamily K, member 3 -1.80292
SLC7A6OS solute carrier family 7, member 6 opposite strand -1.79535
RNF215 ring finger protein 215 -1.79437
C6ORF120 chromosome 6 open reading frame 120 -1.78092
PHLDA1 pleckstrin homology-like domain, family A, member 1 -1.77716
PEX11B peroxisomal biogenesis factor 11 beta -1.77664
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.77602
GADD45B growth arrest and DNA-damage-inducible, beta -1.77598
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.77578
H2AFX H2A histone family, member X -1.77399
NGDN neuroguidin, EIF4E binding protein -1.77327
EMP2 epithelial membrane protein 2 -1.77298
PAPD4 PAP associated domain containing 4 -1.77293
RNF169 ring finger protein 169 -1.76743
MRPL51 mitochondrial ribosomal protein L51 -1.76658
ASS1 argininosuccinate synthase 1 -1.76598
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.75941
ZNF574 zinc finger protein 574 -1.75879
RNF31 ring finger protein 31 -1.74695
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -1.7421
MARS2 methionyl-tRNA synthetase 2, mitochondrial -1.73849
POLRMT polymerase (RNA) mitochondrial (DNA directed) -1.73524
OR1A1 olfactory receptor, family 1, subfamily A, member 1 -1.73416
ADGRA2 adhesion G protein-coupled receptor A2 -1.73196
MRPL1 mitochondrial ribosomal protein L1 -1.73135
ZNF106 zinc finger protein 106 -1.72394
MUL1 mitochondrial E3 ubiquitin protein ligase 1 -1.71739
MTFR2 mitochondrial fission regulator 2 -1.71508
MED10 mediator complex subunit 10 -1.71406
RMDN2 regulator of microtubule dynamics 2 -1.71278
KIFC3 kinesin family member C3 -1.71102
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) -1.71053
LMOD1 leiomodin 1 (smooth muscle) -1.71014
ATE1 arginyltransferase 1 -1.70536
ZFPM1 zinc finger protein, FOG family member 1 -1.698
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -1.69767
GJB5 gap junction protein, beta 5, 31.1kDa -1.69753
BAG1 BCL2-associated athanogene -1.69707
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.69341
PPCS phosphopantothenoylcysteine synthetase -1.69246
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa -1.69042
KLF4 Kruppel-like factor 4 (gut) -1.6885
TICRR TOPBP1-interacting checkpoint and replication regulator -1.68822
CTNNBL1 catenin, beta like 1 -1.68733
MED30 mediator complex subunit 30 -1.68659
S100A6 S100 calcium binding protein A6 -1.67736
RNPEP arginyl aminopeptidase (aminopeptidase B) -1.67615
CFDP1 craniofacial development protein 1 -1.67059
ATP7B ATPase, Cu++ transporting, beta polypeptide -1.6661
MRPL10 mitochondrial ribosomal protein L10 -1.66272
SCYL1 SCY1-like 1 (S. cerevisiae) -1.66064
MRPS16 mitochondrial ribosomal protein S16 -1.65615
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -1.65434
PRSS36 protease, serine, 36 -1.65256
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -1.65026
LRRC59 leucine rich repeat containing 59 -1.64917
EME1 essential meiotic structure-specific endonuclease 1 -1.64848
SCAMP5 secretory carrier membrane protein 5 -1.64478
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -1.64418
HIST1H2BD histone cluster 1, H2bd -1.64189
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -1.63163
CYCS cytochrome c, somatic -1.6304
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -1.63022
CEP170B centrosomal protein 170B -1.62477
MRPL40 mitochondrial ribosomal protein L40 -1.62147
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -1.62106
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -1.61085
FOXK1 forkhead box K1 -1.60834
GRB2 growth factor receptor-bound protein 2 -1.60609
RNF141 ring finger protein 141 -1.60586
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -1.6057
ORAOV1 oral cancer overexpressed 1 -1.60451
PPP1R9A protein phosphatase 1, regulatory subunit 9A -1.60401
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -1.60044
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -1.59866
BYSL bystin-like -1.59738
RAN RAN, member RAS oncogene family -1.59466
WDFY1 WD repeat and FYVE domain containing 1 -1.59266
RFC2 replication factor C (activator 1) 2, 40kDa -1.59219
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase -1.59083
KIF3B kinesin family member 3B -1.57966
NECAP2 NECAP endocytosis associated 2 -1.57952
FKBPL FK506 binding protein like -1.57925
RPL27 ribosomal protein L27 -1.5785
SLC35F5 solute carrier family 35, member F5 -1.57594
UFM1 ubiquitin-fold modifier 1 -1.57494
PCNXL4 pecanex-like 4 (Drosophila) -1.57181
UBFD1 ubiquitin family domain containing 1 -1.569
ELOF1 elongation factor 1 homolog (S. cerevisiae) -1.56273
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 -1.55669
MRPL19 mitochondrial ribosomal protein L19 -1.55654
HIST3H2BB histone cluster 3, H2bb -1.55312
RRP1B ribosomal RNA processing 1B -1.55182
METTL18 methyltransferase like 18 -1.55151
NPY2R neuropeptide Y receptor Y2 -1.55079
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) -1.54888
PLRG1 pleiotropic regulator 1 -1.54699
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -1.54648
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -1.545
ECHDC2 enoyl CoA hydratase domain containing 2 -1.54344
ADAM17 ADAM metallopeptidase domain 17 -1.53846
DPH7 diphthamide biosynthesis 7 -1.53137
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.52913
SART1 squamous cell carcinoma antigen recognized by T cells -1.52853
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -1.5255
PFDN6 prefoldin subunit 6 -1.52263
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -1.52223
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -1.51904
GLRX3 glutaredoxin 3 -1.51761
PLK1 polo-like kinase 1 -1.51748
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -1.51679
SMAD7 SMAD family member 7 -1.51631
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -1.51569
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -1.51547
ATG4D autophagy related 4D, cysteine peptidase -1.51326
KLHDC10 kelch domain containing 10 -1.51202
IFT20 intraflagellar transport 20 -1.50614
ASGR2 asialoglycoprotein receptor 2 -1.50279
SIAH2 siah E3 ubiquitin protein ligase 2 -1.49496
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -1.49302
PEX11A peroxisomal biogenesis factor 11 alpha -1.48833
SFN stratifin -1.48816
IRGQ immunity-related GTPase family, Q -1.48637
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -1.48532
MTF2 metal response element binding transcription factor 2 -1.48323
SDHAF4 succinate dehydrogenase complex assembly factor 4 -1.4827
PSEN1 presenilin 1 -1.48136
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -1.47937
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -1.4788
EIF3L eukaryotic translation initiation factor 3, subunit L -1.47551
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -1.47462
IFNLR1 interferon, lambda receptor 1 -1.47099
DGAT2 diacylglycerol O-acyltransferase 2 -1.46745
PPP4R2 protein phosphatase 4, regulatory subunit 2 -1.46731
NIPAL3 NIPA-like domain containing 3 -1.46396
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.46349
KDM1A lysine (K)-specific demethylase 1A -1.46292
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -1.4607
SAP30BP SAP30 binding protein -1.46023
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -1.4598
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.45826
ENTHD2 ENTH domain containing 2 -1.45818
EXOSC2 exosome component 2 -1.45502
NSF N-ethylmaleimide-sensitive factor -1.45103
PKP2 plakophilin 2 -1.44474
GLIPR1L2 GLI pathogenesis-related 1 like 2 -1.44436
ZPR1 ZPR1 zinc finger -1.44315
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -1.43932
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 -1.43781
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -1.43739
TUBD1 tubulin, delta 1 -1.43677
GRAMD1A GRAM domain containing 1A -1.43383
C20ORF24 chromosome 20 open reading frame 24 -1.43055
EIF3G eukaryotic translation initiation factor 3, subunit G -1.42665
ITPKC inositol-trisphosphate 3-kinase C -1.42552
CUL5 cullin 5 -1.42475
ANGPTL4 angiopoietin-like 4 -1.42427