CDK8_knockdown_130_GSE30816 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30816
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Genes

600 genes differentially expressed following the CDK8_knockdown_130_GSE30816 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
C9ORF40 chromosome 9 open reading frame 40 3.78312
TM2D1 TM2 domain containing 1 3.64717
WDR45 WD repeat domain 45 3.47478
ANXA3 annexin A3 3.42219
KRT8 keratin 8, type II 3.38567
BTG3 BTG family, member 3 3.19511
RCN1 reticulocalbin 1, EF-hand calcium binding domain 3.14356
BOLA3 bolA family member 3 3.08139
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.07347
ANKLE2 ankyrin repeat and LEM domain containing 2 3.01597
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.94286
ANXA1 annexin A1 2.93804
DOK2 docking protein 2, 56kDa 2.88701
VWA9 von Willebrand factor A domain containing 9 2.8589
CMTR1 cap methyltransferase 1 2.84577
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 2.74664
CTDNEP1 CTD nuclear envelope phosphatase 1 2.74264
STX8 syntaxin 8 2.72848
SPATS2L spermatogenesis associated, serine-rich 2-like 2.66634
PLXNA4 plexin A4 2.66522
FRMD8 FERM domain containing 8 2.66144
MIEN1 migration and invasion enhancer 1 2.661
GLIS2 GLIS family zinc finger 2 2.65616
BAHCC1 BAH domain and coiled-coil containing 1 2.65024
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2.64326
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.64227
GAS2L3 growth arrest-specific 2 like 3 2.63909
CARHSP1 calcium regulated heat stable protein 1, 24kDa 2.62119
ACTA1 actin, alpha 1, skeletal muscle 2.61706
MTCH1 mitochondrial carrier 1 2.60184
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 2.58453
WDR1 WD repeat domain 1 2.56606
RRAGD Ras-related GTP binding D 2.55473
CREB3 cAMP responsive element binding protein 3 2.55455
MAN2A1 mannosidase, alpha, class 2A, member 1 2.54059
GBP2 guanylate binding protein 2, interferon-inducible 2.52458
AMOTL2 angiomotin like 2 2.50727
CD81 CD81 molecule 2.50109
GPM6B glycoprotein M6B 2.49485
PARVA parvin, alpha 2.48186
RBMS1 RNA binding motif, single stranded interacting protein 1 2.47961
WBP5 WW domain binding protein 5 2.47846
DHCR24 24-dehydrocholesterol reductase 2.45686
LEF1 lymphoid enhancer-binding factor 1 2.44131
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2 2.42146
CCDC12 coiled-coil domain containing 12 2.41987
TSEN15 TSEN15 tRNA splicing endonuclease subunit 2.40875
SIDT2 SID1 transmembrane family, member 2 2.38481
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.37406
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 2.35993
HOXC9 homeobox C9 2.35852
ADGRL2 adhesion G protein-coupled receptor L2 2.35349
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.34223
MAPK12 mitogen-activated protein kinase 12 2.3355
TSPAN6 tetraspanin 6 2.33098
CENPW centromere protein W 2.32649
TMEM55A transmembrane protein 55A 2.32579
GBP3 guanylate binding protein 3 2.32157
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.2732
WNT6 wingless-type MMTV integration site family, member 6 2.26867
MEST mesoderm specific transcript 2.26027
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.2573
CNTF ciliary neurotrophic factor 2.25494
VGLL3 vestigial-like family member 3 2.22209
PLXNB1 plexin B1 2.2106
NT5C2 5'-nucleotidase, cytosolic II 2.21018
PHLDA1 pleckstrin homology-like domain, family A, member 1 2.19876
FBXL7 F-box and leucine-rich repeat protein 7 2.19849
TFIP11 tuftelin interacting protein 11 2.18719
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 2.17761
DNLZ DNL-type zinc finger 2.17041
SEPW1 selenoprotein W, 1 2.16564
TMEM159 transmembrane protein 159 2.15475
WT1 Wilms tumor 1 2.15457
FAM120A family with sequence similarity 120A 2.15422
RAB1B RAB1B, member RAS oncogene family 2.1517
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.13851
TMEM80 transmembrane protein 80 2.12015
SQLE squalene epoxidase 2.11822
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 2.09748
TPD52L2 tumor protein D52-like 2 2.09706
SF3A1 splicing factor 3a, subunit 1, 120kDa 2.09433
OGFR opioid growth factor receptor 2.08212
DSCR3 Down syndrome critical region 3 2.06831
ABHD17C abhydrolase domain containing 17C 2.06756
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 2.06467
SERTAD2 SERTA domain containing 2 2.05033
PLAGL1 pleiomorphic adenoma gene-like 1 2.04705
STRAP serine/threonine kinase receptor associated protein 2.0415
DCPS decapping enzyme, scavenger 2.02015
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 2.02008
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 2.01635
EXT1 exostosin glycosyltransferase 1 2.0144
RPP25L ribonuclease P/MRP 25kDa subunit-like 2.01058
TMEM183A transmembrane protein 183A 2.00837
POR P450 (cytochrome) oxidoreductase 2.00607
ING5 inhibitor of growth family, member 5 2.00248
FAM46B family with sequence similarity 46, member B 1.99708
TYMP thymidine phosphorylase 1.99108
GADD45A growth arrest and DNA-damage-inducible, alpha 1.98911
PLAUR plasminogen activator, urokinase receptor 1.98662
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.98284
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 1.97679
SAP30L SAP30-like 1.96675
TM9SF3 transmembrane 9 superfamily member 3 1.96395
DHDDS dehydrodolichyl diphosphate synthase 1.95692
MAP7D1 MAP7 domain containing 1 1.95401
C11ORF31 chromosome 11 open reading frame 31 1.94785
GNPAT glyceronephosphate O-acyltransferase 1.9428
FAM174A family with sequence similarity 174, member A 1.9407
GRIK5 glutamate receptor, ionotropic, kainate 5 1.93612
C19ORF24 chromosome 19 open reading frame 24 1.92245
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 1.92109
SKAP2 src kinase associated phosphoprotein 2 1.90234
SRPRB signal recognition particle receptor, B subunit 1.90057
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 1.8987
CRLF2 cytokine receptor-like factor 2 1.89034
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative) 1.89011
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.88823
ZC3H7B zinc finger CCCH-type containing 7B 1.87572
PGM1 phosphoglucomutase 1 1.87121
OSBPL5 oxysterol binding protein-like 5 1.86192
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.85873
ZMYND8 zinc finger, MYND-type containing 8 1.85622
C9ORF41 chromosome 9 open reading frame 41 1.84992
RGMA repulsive guidance molecule family member a 1.84812
FMNL2 formin-like 2 1.84646
STARD10 StAR-related lipid transfer (START) domain containing 10 1.84556
MESDC1 mesoderm development candidate 1 1.84443
FZD7 frizzled class receptor 7 1.84329
TAS2R39 taste receptor, type 2, member 39 1.83715
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.82478
ZNF48 zinc finger protein 48 1.8235
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 1.82212
GINS3 GINS complex subunit 3 (Psf3 homolog) 1.81815
KRT18 keratin 18, type I 1.81785
NCEH1 neutral cholesterol ester hydrolase 1 1.81606
EXOSC4 exosome component 4 1.80902
IFITM3 interferon induced transmembrane protein 3 1.80781
FKBP10 FK506 binding protein 10, 65 kDa 1.79953
TAPBP TAP binding protein (tapasin) 1.79863
TMEM50B transmembrane protein 50B 1.798
COLEC12 collectin sub-family member 12 1.79594
ABHD4 abhydrolase domain containing 4 1.79061
TRAF2 TNF receptor-associated factor 2 1.79005
CSNK1D casein kinase 1, delta 1.78894
UBC ubiquitin C 1.78681
CSRP1 cysteine and glycine-rich protein 1 1.78412
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.78141
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 1.78017
FAM195B family with sequence similarity 195, member B 1.77778
FAM96A family with sequence similarity 96, member A 1.75094
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.75057
TOB2 transducer of ERBB2, 2 1.75016
ZNF131 zinc finger protein 131 1.74782
MUC20 mucin 20, cell surface associated 1.7459
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 1.74012
ANKRD13B ankyrin repeat domain 13B 1.73799
PRDX3 peroxiredoxin 3 1.73796
VWA5A von Willebrand factor A domain containing 5A 1.73744
FAM98A family with sequence similarity 98, member A 1.73135
GBE1 glucan (1,4-alpha-), branching enzyme 1 1.72644
SEPT4 septin 4 1.71606
PGRMC1 progesterone receptor membrane component 1 1.71506
VEZF1 vascular endothelial zinc finger 1 1.70763
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 1.70164
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.69734
BICD2 bicaudal D homolog 2 (Drosophila) 1.69527
SNX15 sorting nexin 15 1.69497
TMEM248 transmembrane protein 248 1.69465
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.69136
KPTN kaptin (actin binding protein) 1.69069
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.68848
CA3 carbonic anhydrase III 1.68622
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 1.68492
MAL mal, T-cell differentiation protein 1.67819
ATP9B ATPase, class II, type 9B 1.67606
FBXO18 F-box protein, helicase, 18 1.6704
KCTD15 potassium channel tetramerization domain containing 15 1.66708
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 1.66665
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 1.66624
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.66576
ZMPSTE24 zinc metallopeptidase STE24 1.66452
BAIAP2 BAI1-associated protein 2 1.66158
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 1.65947
RRM1 ribonucleotide reductase M1 1.65649
RWDD4 RWD domain containing 4 1.65492
C14ORF1 chromosome 14 open reading frame 1 1.65284
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 1.65151
SNTA1 syntrophin, alpha 1 1.64403
CRLS1 cardiolipin synthase 1 1.64114
TESK1 testis-specific kinase 1 1.63732
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.63648
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.63353
PUM2 pumilio RNA-binding family member 2 1.63183
MBNL2 muscleblind-like splicing regulator 2 1.63132
SERF2 small EDRK-rich factor 2 1.63037
TXNRD1 thioredoxin reductase 1 1.62858
USP25 ubiquitin specific peptidase 25 1.62197
CNN2 calponin 2 1.62192
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.62038
DIS3L DIS3 like exosome 3'-5' exoribonuclease 1.61931
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 1.61619
IMPAD1 inositol monophosphatase domain containing 1 1.61516
TFE3 transcription factor binding to IGHM enhancer 3 1.61201
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.61122
PDLIM7 PDZ and LIM domain 7 (enigma) 1.60992
CCDC132 coiled-coil domain containing 132 1.60932
SRSF9 serine/arginine-rich splicing factor 9 1.60365
PARP9 poly (ADP-ribose) polymerase family, member 9 1.58966
SELK selenoprotein K 1.58884
FNDC4 fibronectin type III domain containing 4 1.58466
SLC38A1 solute carrier family 38, member 1 1.58246
RNF149 ring finger protein 149 1.57897
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough 1.57786
E2F5 E2F transcription factor 5, p130-binding 1.5756
THBS3 thrombospondin 3 1.57488
PHLDB1 pleckstrin homology-like domain, family B, member 1 1.56604
SOCS1 suppressor of cytokine signaling 1 1.55936
SGPL1 sphingosine-1-phosphate lyase 1 1.55733
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 1.55482
ZDHHC3 zinc finger, DHHC-type containing 3 1.54288
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1.5414
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 1.53676
TRADD TNFRSF1A-associated via death domain 1.5348
CCNI cyclin I 1.53112
C8ORF33 chromosome 8 open reading frame 33 1.52856
TAGLN transgelin 1.52213
CST3 cystatin C 1.5205
CHMP2B charged multivesicular body protein 2B 1.51426
PITPNA phosphatidylinositol transfer protein, alpha 1.51171
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 1.50985
ADM adrenomedullin 1.50734
CBR3 carbonyl reductase 3 1.50444
SEC61G Sec61 gamma subunit 1.50262
PHLDB2 pleckstrin homology-like domain, family B, member 2 1.50246
MRAS muscle RAS oncogene homolog 1.50195
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.49717
INO80C INO80 complex subunit C 1.49579
EXOC3L4 exocyst complex component 3-like 4 1.49472
IPO13 importin 13 1.49419
BHLHB9 basic helix-loop-helix domain containing, class B, 9 1.4934
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.48856
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.48724
MMP23B matrix metallopeptidase 23B 1.48593
GID4 GID complex subunit 4 1.48444
STK11 serine/threonine kinase 11 1.48247
CDK13 cyclin-dependent kinase 13 1.48174
SIL1 SIL1 nucleotide exchange factor 1.48067
CXXC5 CXXC finger protein 5 1.4806
CNN3 calponin 3, acidic 1.47809
LPAR6 lysophosphatidic acid receptor 6 1.47756
FADD Fas (TNFRSF6)-associated via death domain 1.47717
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.47671
SSBP3 single stranded DNA binding protein 3 1.46859
TFRC transferrin receptor 1.46465
COMMD3 COMM domain containing 3 1.46266
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.46204
BABAM1 BRISC and BRCA1 A complex member 1 1.46065
ASB6 ankyrin repeat and SOCS box containing 6 1.45946
EBP emopamil binding protein (sterol isomerase) 1.45893
SFRP2 secreted frizzled-related protein 2 1.4578
WISP1 WNT1 inducible signaling pathway protein 1 1.45553
PTPRF protein tyrosine phosphatase, receptor type, F 1.45548
GMFB glia maturation factor, beta 1.45368
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.4511
CCNY cyclin Y 1.45043
SUMO2 small ubiquitin-like modifier 2 1.448
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 1.44515
SPRYD7 SPRY domain containing 7 1.44416
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.44062
PRNP prion protein 1.43799
KIF5B kinesin family member 5B 1.43535
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.43399
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.43335
VASN vasorin 1.43043
DUSP14 dual specificity phosphatase 14 1.43037
ARRDC1 arrestin domain containing 1 1.43012
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.42833
NPDC1 neural proliferation, differentiation and control, 1 1.42791
GSTM3 glutathione S-transferase mu 3 (brain) 1.42785
RAB31 RAB31, member RAS oncogene family 1.42754
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.42685
PDS5B PDS5 cohesin associated factor B 1.42138
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.41806
DIAPH3 diaphanous-related formin 3 1.41756
NT5DC2 5'-nucleotidase domain containing 2 1.4159
TPST2 tyrosylprotein sulfotransferase 2 1.4131
KLF6 Kruppel-like factor 6 1.41286
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.41249
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 1.41144
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.41116
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 1.41069
CPA4 carboxypeptidase A4 1.40858
LURAP1L leucine rich adaptor protein 1-like 1.40557
TRIP6 thyroid hormone receptor interactor 6 1.40479
ACTB actin, beta 1.40217
LAMA5 laminin, alpha 5 1.40055
LAPTM4A lysosomal protein transmembrane 4 alpha 1.39711
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 1.39672

decreased expression

Symbol Name Standardized Value
MTFR2 mitochondrial fission regulator 2 -4.24211
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.83527
CLUAP1 clusterin associated protein 1 -3.46222
BRAP BRCA1 associated protein -3.34914
C3ORF67 chromosome 3 open reading frame 67 -3.1936
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -3.00251
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -2.99934
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -2.97842
GLS2 glutaminase 2 (liver, mitochondrial) -2.95877
KIF24 kinesin family member 24 -2.92632
ZNF710 zinc finger protein 710 -2.90635
AGBL3 ATP/GTP binding protein-like 3 -2.87071
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit -2.85853
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.84344
HIST4H4 histone cluster 4, H4 -2.78831
BCL6B B-cell CLL/lymphoma 6, member B -2.75807
CALML4 calmodulin-like 4 -2.71321
PLCD1 phospholipase C, delta 1 -2.69347
WDR34 WD repeat domain 34 -2.6877
NIT1 nitrilase 1 -2.67637
PADI3 peptidyl arginine deiminase, type III -2.67461
MIB2 mindbomb E3 ubiquitin protein ligase 2 -2.66024
ZPR1 ZPR1 zinc finger -2.65161
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.642
EXOC2 exocyst complex component 2 -2.60557
ZFP41 ZFP41 zinc finger protein -2.60299
MUT methylmalonyl CoA mutase -2.60189
AAMP angio-associated, migratory cell protein -2.59431
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -2.58964
PNKD paroxysmal nonkinesigenic dyskinesia -2.57762
HAX1 HCLS1 associated protein X-1 -2.5708
SUGP1 SURP and G patch domain containing 1 -2.56604
FBXO9 F-box protein 9 -2.54091
LDHB lactate dehydrogenase B -2.53875
PLA2G5 phospholipase A2, group V -2.53721
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.52731
ATMIN ATM interactor -2.52353
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.51129
MRS2 MRS2 magnesium transporter -2.49558
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) -2.49139
CSRP2 cysteine and glycine-rich protein 2 -2.48555
TOR1AIP2 torsin A interacting protein 2 -2.46252
TPX2 TPX2, microtubule-associated -2.46142
HIST3H2A histone cluster 3, H2a -2.46034
FDX1 ferredoxin 1 -2.44134
TRAF3IP2 TRAF3 interacting protein 2 -2.43708
RNASEH2A ribonuclease H2, subunit A -2.42616
GSG2 germ cell associated 2 (haspin) -2.42338
NASP nuclear autoantigenic sperm protein (histone-binding) -2.38494
ZNF2 zinc finger protein 2 -2.37795
TMEM218 transmembrane protein 218 -2.36901
WTIP Wilms tumor 1 interacting protein -2.36791
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.36676
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.34357
MTMR3 myotubularin related protein 3 -2.34298
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.33965
PGPEP1 pyroglutamyl-peptidase I -2.31976
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa -2.29113
GPANK1 G patch domain and ankyrin repeats 1 -2.29081
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.28577
H2AFX H2A histone family, member X -2.27824
SETD4 SET domain containing 4 -2.27435
WDR35 WD repeat domain 35 -2.26366
GCDH glutaryl-CoA dehydrogenase -2.26304
CAMLG calcium modulating ligand -2.25708
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.24957
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -2.24765
NOP9 NOP9 nucleolar protein -2.24012
PRSS36 protease, serine, 36 -2.22796
SCNM1 sodium channel modifier 1 -2.22027
ZNF688 zinc finger protein 688 -2.21974
NDRG2 NDRG family member 2 -2.21156
TRUB1 TruB pseudouridine (psi) synthase family member 1 -2.20554
C11ORF1 chromosome 11 open reading frame 1 -2.20499
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 -2.19899
KDM1A lysine (K)-specific demethylase 1A -2.19479
ITPKC inositol-trisphosphate 3-kinase C -2.19329
VCPKMT valosin containing protein lysine (K) methyltransferase -2.19085
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -2.18457
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -2.18115
SEC23B Sec23 homolog B (S. cerevisiae) -2.1786
ZFAND2B zinc finger, AN1-type domain 2B -2.17635
DCAF4 DDB1 and CUL4 associated factor 4 -2.17538
MTRF1 mitochondrial translational release factor 1 -2.17191
ZSWIM1 zinc finger, SWIM-type containing 1 -2.17099
COG4 component of oligomeric golgi complex 4 -2.16895
RBM17 RNA binding motif protein 17 -2.15944
MANBAL mannosidase, beta A, lysosomal-like -2.15756
ECHDC2 enoyl CoA hydratase domain containing 2 -2.15262
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -2.14831
TUFM Tu translation elongation factor, mitochondrial -2.14816
MRPL38 mitochondrial ribosomal protein L38 -2.14788
TUBD1 tubulin, delta 1 -2.13958
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.1393
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -2.13521
PPP1R35 protein phosphatase 1, regulatory subunit 35 -2.13034
WDR31 WD repeat domain 31 -2.12179
NTPCR nucleoside-triphosphatase, cancer-related -2.11589
NOP14 NOP14 nucleolar protein -2.11313
CUL5 cullin 5 -2.11115
DCTN5 dynactin 5 (p25) -2.0943
CENPU centromere protein U -2.09051
SCYL3 SCY1-like 3 (S. cerevisiae) -2.08077
ARRDC4 arrestin domain containing 4 -2.079
MIPEP mitochondrial intermediate peptidase -2.07879
BLNK B-cell linker -2.07653
TXNL4B thioredoxin-like 4B -2.07026
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.06695
TIGD2 tigger transposable element derived 2 -2.06635
ZBTB3 zinc finger and BTB domain containing 3 -2.06283
CYB5R1 cytochrome b5 reductase 1 -2.06208
SPN sialophorin -2.05947
BUD13 BUD13 homolog (S. cerevisiae) -2.05153
PGAM2 phosphoglycerate mutase 2 (muscle) -2.04548
RNF169 ring finger protein 169 -2.04212
HEMK1 HemK methyltransferase family member 1 -2.04127
TKFC triokinase/FMN cyclase -2.03885
KLF3 Kruppel-like factor 3 (basic) -2.03749
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.03393
CISD3 CDGSH iron sulfur domain 3 -2.03009
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.02977
GEMIN5 gem (nuclear organelle) associated protein 5 -2.02365
SIRT3 sirtuin 3 -2.01912
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.00959
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.00647
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.99893
LCMT1 leucine carboxyl methyltransferase 1 -1.99302
IL12RB1 interleukin 12 receptor, beta 1 -1.99057
C6ORF120 chromosome 6 open reading frame 120 -1.98901
FLAD1 flavin adenine dinucleotide synthetase 1 -1.98898
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -1.98399
NSUN4 NOP2/Sun domain family, member 4 -1.97531
TMC6 transmembrane channel-like 6 -1.96898
MRPL22 mitochondrial ribosomal protein L22 -1.96593
PYCARD PYD and CARD domain containing -1.96258
CYB561A3 cytochrome b561 family, member A3 -1.96252
PKN1 protein kinase N1 -1.95041
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -1.94454
RAN RAN, member RAS oncogene family -1.9443
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -1.94281
DALRD3 DALR anticodon binding domain containing 3 -1.94241
ZNF566 zinc finger protein 566 -1.94177
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.94061
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -1.93923
ZFPM1 zinc finger protein, FOG family member 1 -1.93348
EPRS glutamyl-prolyl-tRNA synthetase -1.92934
NFS1 NFS1 cysteine desulfurase -1.92751
ENTHD2 ENTH domain containing 2 -1.92662
FAM132A family with sequence similarity 132, member A -1.92294
AARSD1 alanyl-tRNA synthetase domain containing 1 -1.91842
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like -1.91674
CA13 carbonic anhydrase XIII -1.91343
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -1.90715
GLRX3 glutaredoxin 3 -1.90368
CSAD cysteine sulfinic acid decarboxylase -1.89995
TBCC tubulin folding cofactor C -1.88683
LENG1 leukocyte receptor cluster (LRC) member 1 -1.88456
PARG poly (ADP-ribose) glycohydrolase -1.8813
CCDC181 coiled-coil domain containing 181 -1.88
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.87835
SUCLG1 succinate-CoA ligase, alpha subunit -1.8778
RHEBL1 Ras homolog enriched in brain like 1 -1.87737
PNKP polynucleotide kinase 3'-phosphatase -1.87132
CDKN3 cyclin-dependent kinase inhibitor 3 -1.86801
DHRS13 dehydrogenase/reductase (SDR family) member 13 -1.8647
ADPGK ADP-dependent glucokinase -1.86304
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -1.86204
RPAP2 RNA polymerase II associated protein 2 -1.85985
FH fumarate hydratase -1.85472
SLC38A2 solute carrier family 38, member 2 -1.85421
EAPP E2F-associated phosphoprotein -1.85165
DUS2 dihydrouridine synthase 2 -1.84427
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -1.84338
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -1.84187
MCL1 myeloid cell leukemia 1 -1.83954
GTF2A2 general transcription factor IIA, 2, 12kDa -1.83818
KRI1 KRI1 homolog (S. cerevisiae) -1.83496
C8ORF82 chromosome 8 open reading frame 82 -1.8338
LSM10 LSM10, U7 small nuclear RNA associated -1.83354
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -1.83087
RFC4 replication factor C (activator 1) 4, 37kDa -1.82871
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M -1.82776
PHC1 polyhomeotic homolog 1 (Drosophila) -1.82449
RXRA retinoid X receptor, alpha -1.81757
ENGASE endo-beta-N-acetylglucosaminidase -1.81681
CCDC51 coiled-coil domain containing 51 -1.81393
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -1.81184
NGRN neugrin, neurite outgrowth associated -1.80852
GLT8D1 glycosyltransferase 8 domain containing 1 -1.80452
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -1.79819
MTUS2 microtubule associated tumor suppressor candidate 2 -1.79525
ATP9A ATPase, class II, type 9A -1.78741
RNF31 ring finger protein 31 -1.77456
SULF2 sulfatase 2 -1.77292
XRCC6BP1 XRCC6 binding protein 1 -1.77075
KLF9 Kruppel-like factor 9 -1.7695
EIF3C eukaryotic translation initiation factor 3, subunit C -1.76509
XPC xeroderma pigmentosum, complementation group C -1.76379
TACC3 transforming, acidic coiled-coil containing protein 3 -1.76227
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.76121
UNG uracil-DNA glycosylase -1.7609
GRIPAP1 GRIP1 associated protein 1 -1.76086
NPHP1 nephronophthisis 1 (juvenile) -1.75856
RPS9 ribosomal protein S9 -1.75829
FUK fucokinase -1.75795
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -1.75494
IRF8 interferon regulatory factor 8 -1.75402
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -1.75353
RNMTL1 RNA methyltransferase like 1 -1.75262
ZGPAT zinc finger, CCCH-type with G patch domain -1.75046
SNAP47 synaptosomal-associated protein, 47kDa -1.74814
COPS4 COP9 signalosome subunit 4 -1.74807
MCM9 minichromosome maintenance complex component 9 -1.74712
SHMT1 serine hydroxymethyltransferase 1 (soluble) -1.74561
FKBPL FK506 binding protein like -1.7424
FAM228B family with sequence similarity 228, member B -1.74038
ACAA2 acetyl-CoA acyltransferase 2 -1.74022
CCDC174 coiled-coil domain containing 174 -1.73685
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -1.73549
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) -1.73146
EIF5B eukaryotic translation initiation factor 5B -1.72954
HDGFRP2 hepatoma-derived growth factor-related protein 2 -1.72492
EFHC1 EF-hand domain (C-terminal) containing 1 -1.72479
WRAP73 WD repeat containing, antisense to TP73 -1.72019
MRPS14 mitochondrial ribosomal protein S14 -1.71547
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -1.71508
CNOT10 CCR4-NOT transcription complex, subunit 10 -1.71295
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.70747
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) -1.70561
MAPK7 mitogen-activated protein kinase 7 -1.69872
KLHDC4 kelch domain containing 4 -1.69514
KCTD18 potassium channel tetramerization domain containing 18 -1.68681
CAPG capping protein (actin filament), gelsolin-like -1.68493
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -1.68299
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -1.68282
CCDC61 coiled-coil domain containing 61 -1.68237
ZBTB43 zinc finger and BTB domain containing 43 -1.68203
ORAOV1 oral cancer overexpressed 1 -1.68053
RAD51 RAD51 recombinase -1.6777
ELL elongation factor RNA polymerase II -1.67739
PNN pinin, desmosome associated protein -1.67692
KCTD5 potassium channel tetramerization domain containing 5 -1.67139
MRPL19 mitochondrial ribosomal protein L19 -1.67061
MRPL18 mitochondrial ribosomal protein L18 -1.66982
PRELID2 PRELI domain containing 2 -1.66736
ZNF296 zinc finger protein 296 -1.66119
ARL13B ADP-ribosylation factor-like 13B -1.65877
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -1.65704
EIF2D eukaryotic translation initiation factor 2D -1.65467
TOR2A torsin family 2, member A -1.65338
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -1.64347
ACOT8 acyl-CoA thioesterase 8 -1.64325
EMP1 epithelial membrane protein 1 -1.63944
KLF4 Kruppel-like factor 4 (gut) -1.63712
NHP2 NHP2 ribonucleoprotein -1.6313
POLL polymerase (DNA directed), lambda -1.63071
DAXX death-domain associated protein -1.62292
TRIB3 tribbles pseudokinase 3 -1.61903
COPS6 COP9 signalosome subunit 6 -1.61664
CD1D CD1d molecule -1.61436
TRAPPC1 trafficking protein particle complex 1 -1.61254
TSTA3 tissue specific transplantation antigen P35B -1.61031
MTIF2 mitochondrial translational initiation factor 2 -1.60735
RPAP3 RNA polymerase II associated protein 3 -1.60727
NCL nucleolin -1.60708
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -1.60607
BYSL bystin-like -1.60424
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -1.60259
KIF3A kinesin family member 3A -1.60126
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -1.60047
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 -1.59926
PGS1 phosphatidylglycerophosphate synthase 1 -1.59112
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -1.5902
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -1.58743
PEX11A peroxisomal biogenesis factor 11 alpha -1.58697
MORN4 MORN repeat containing 4 -1.58495
NMT1 N-myristoyltransferase 1 -1.58392
SIRT4 sirtuin 4 -1.57738
OXSM 3-oxoacyl-ACP synthase, mitochondrial -1.57515
GLYCTK glycerate kinase -1.57402
PFDN6 prefoldin subunit 6 -1.57352
WFDC1 WAP four-disulfide core domain 1 -1.57296
C1ORF116 chromosome 1 open reading frame 116 -1.57178
SIPA1L2 signal-induced proliferation-associated 1 like 2 -1.57062
KXD1 KxDL motif containing 1 -1.5691
GTPBP4 GTP binding protein 4 -1.56895
KIZ kizuna centrosomal protein -1.56795
PROS1 protein S (alpha) -1.56701
PDCD2L programmed cell death 2-like -1.56524
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -1.56519
MOCS2 molybdenum cofactor synthesis 2 -1.56453
GMFG glia maturation factor, gamma -1.5643
GPATCH2 G patch domain containing 2 -1.56424
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -1.56381
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -1.5635
CDK11A cyclin-dependent kinase 11A -1.56045
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -1.56011
WASH1 WAS protein family homolog 1 -1.5531
RAB40C RAB40C, member RAS oncogene family -1.55144
TMCO6 transmembrane and coiled-coil domains 6 -1.55033