CDK8_knockdown_161_GSE38061 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38061
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Genes

600 genes differentially expressed following the CDK8_knockdown_161_GSE38061 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
COL6A1 collagen, type VI, alpha 1 4.38381
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 3.612
LOC101927181 uncharacterized LOC101927181 3.46764
PLEC plectin 3.42393
CUEDC1 CUE domain containing 1 3.26005
C15ORF41 chromosome 15 open reading frame 41 3.22536
ANO1 anoctamin 1, calcium activated chloride channel 3.15777
CNTNAP3 contactin associated protein-like 3 3.14712
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 3.13849
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 3.1089
NRBP2 nuclear receptor binding protein 2 3.10135
SATB2 SATB homeobox 2 3.09946
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.98741
PGM1 phosphoglucomutase 1 2.97521
SH3BP2 SH3-domain binding protein 2 2.91706
PANX1 pannexin 1 2.90662
ZDHHC1 zinc finger, DHHC-type containing 1 2.8972
HLF hepatic leukemia factor 2.86974
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2.86752
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 2.84752
TRIM47 tripartite motif containing 47 2.82329
TOM1L2 target of myb1-like 2 (chicken) 2.81259
MAVS mitochondrial antiviral signaling protein 2.77972
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 2.77841
DDA1 DET1 and DDB1 associated 1 2.76484
SOGA1 suppressor of glucose, autophagy associated 1 2.7633
SLC4A3 solute carrier family 4 (anion exchanger), member 3 2.74024
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 2.73176
EPN2 epsin 2 2.7165
SLC38A10 solute carrier family 38, member 10 2.67129
ACTN4 actinin, alpha 4 2.66071
ZNF276 zinc finger protein 276 2.65676
SBF1 SET binding factor 1 2.64789
PLCG1 phospholipase C, gamma 1 2.64545
TP53I3 tumor protein p53 inducible protein 3 2.61398
PANK1 pantothenate kinase 1 2.61364
EVPL envoplakin 2.60164
TNS4 tensin 4 2.59914
LRRC41 leucine rich repeat containing 41 2.58954
RINL Ras and Rab interactor-like 2.54913
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 2.54222
GRID1 glutamate receptor, ionotropic, delta 1 2.52581
FAM102A family with sequence similarity 102, member A 2.51603
PRKCDBP protein kinase C, delta binding protein 2.50774
NECAB3 N-terminal EF-hand calcium binding protein 3 2.48846
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.48576
RNF43 ring finger protein 43 2.47929
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.46498
VASH1 vasohibin 1 2.42784
FRY furry homolog (Drosophila) 2.40729
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.38031
HS1BP3 HCLS1 binding protein 3 2.37164
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.36578
MYO1E myosin IE 2.3559
PARP3 poly (ADP-ribose) polymerase family, member 3 2.35286
BAG3 BCL2-associated athanogene 3 2.34301
NEBL nebulette 2.33953
MUM1 melanoma associated antigen (mutated) 1 2.33134
ALS2CL ALS2 C-terminal like 2.32755
GLIS3 GLIS family zinc finger 3 2.30944
VSNL1 visinin-like 1 2.30735
ATOX1 antioxidant 1 copper chaperone 2.3021
HR hair growth associated 2.2926
SFXN3 sideroflexin 3 2.2722
TBC1D4 TBC1 domain family, member 4 2.27089
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.26548
DALRD3 DALR anticodon binding domain containing 3 2.25334
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.242
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.24004
MN1 meningioma (disrupted in balanced translocation) 1 2.14833
SAR1A secretion associated, Ras related GTPase 1A 2.10773
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.08359
CSF1 colony stimulating factor 1 (macrophage) 2.07896
PGBD4 piggyBac transposable element derived 4 2.0594
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 2.05798
STARD3 StAR-related lipid transfer (START) domain containing 3 2.0452
SOX9 SRY (sex determining region Y)-box 9 2.039
CLIC5 chloride intracellular channel 5 2.03604
KRT8 keratin 8, type II 2.03428
LAMB1 laminin, beta 1 2.02516
SCAF8 SR-related CTD-associated factor 8 2.02141
ZNF385A zinc finger protein 385A 2.01463
PTCHD4 patched domain containing 4 2.00423
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 1.9833
GRK5 G protein-coupled receptor kinase 5 1.97724
USP36 ubiquitin specific peptidase 36 1.97255
NBEAL2 neurobeachin-like 2 1.95999
SYCP2 synaptonemal complex protein 2 1.949
TGFB2 transforming growth factor, beta 2 1.94372
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.94264
EXOC7 exocyst complex component 7 1.94124
SULF2 sulfatase 2 1.94078
CREB3L3 cAMP responsive element binding protein 3-like 3 1.91944
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.91854
MAST2 microtubule associated serine/threonine kinase 2 1.91372
PCDH1 protocadherin 1 1.90795
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 1.90395
MYLK myosin light chain kinase 1.90306
ORAI3 ORAI calcium release-activated calcium modulator 3 1.88447
INF2 inverted formin, FH2 and WH2 domain containing 1.88279
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.87855
KLRC3 killer cell lectin-like receptor subfamily C, member 3 1.87153
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 1.86786
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.86713
JAG1 jagged 1 1.86422
ZNF358 zinc finger protein 358 1.863
ZNF251 zinc finger protein 251 1.86161
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 1.85467
TMEM43 transmembrane protein 43 1.8482
ARHGAP4 Rho GTPase activating protein 4 1.84295
HDAC4 histone deacetylase 4 1.8424
SMAD3 SMAD family member 3 1.83387
ZBED2 zinc finger, BED-type containing 2 1.82508
SUSD2 sushi domain containing 2 1.81114
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 1.79738
ADORA2B adenosine A2b receptor 1.77859
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.77623
EMILIN2 elastin microfibril interfacer 2 1.76809
CST3 cystatin C 1.76748
PRPF3 pre-mRNA processing factor 3 1.76129
BMP4 bone morphogenetic protein 4 1.76058
ABLIM1 actin binding LIM protein 1 1.75177
NCEH1 neutral cholesterol ester hydrolase 1 1.74739
ZNF460 zinc finger protein 460 1.74593
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 1.74591
AK4 adenylate kinase 4 1.74554
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.74123
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 1.73932
TRIP6 thyroid hormone receptor interactor 6 1.73708
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.73447
PNPO pyridoxamine 5'-phosphate oxidase 1.73303
FAM131A family with sequence similarity 131, member A 1.73273
LYZ lysozyme 1.72356
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 1.71549
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 1.71506
LZTR1 leucine-zipper-like transcription regulator 1 1.71403
OPLAH 5-oxoprolinase (ATP-hydrolysing) 1.70958
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.69437
CLCA2 chloride channel accessory 2 1.69071
LAMA5 laminin, alpha 5 1.6758
SRRM2 serine/arginine repetitive matrix 2 1.66906
AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.66883
GPR135 G protein-coupled receptor 135 1.66773
MECOM MDS1 and EVI1 complex locus 1.66544
ADAM19 ADAM metallopeptidase domain 19 1.65396
TM4SF18 transmembrane 4 L six family member 18 1.65234
SERINC2 serine incorporator 2 1.6512
KCTD13 potassium channel tetramerization domain containing 13 1.64941
ITGB5 integrin, beta 5 1.64742
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.64671
LGMN legumain 1.64313
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 1.64156
WNT16 wingless-type MMTV integration site family, member 16 1.63817
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 1.63034
KLF5 Kruppel-like factor 5 (intestinal) 1.62297
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.6205
BCL2L1 BCL2-like 1 1.61931
IRGQ immunity-related GTPase family, Q 1.60658
GLTSCR2 glioma tumor suppressor candidate region gene 2 1.60269
DOCK5 dedicator of cytokinesis 5 1.59655
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.59367
PMP22 peripheral myelin protein 22 1.59306
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 1.58782
NOL4L nucleolar protein 4-like 1.58686
FAM160B2 family with sequence similarity 160, member B2 1.58638
TOB2 transducer of ERBB2, 2 1.58124
IVD isovaleryl-CoA dehydrogenase 1.58116
BCAR1 breast cancer anti-estrogen resistance 1 1.58113
VAMP3 vesicle-associated membrane protein 3 1.57551
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.57374
RIMS2 regulating synaptic membrane exocytosis 2 1.56808
MSLN mesothelin 1.56597
ITGB4 integrin, beta 4 1.56454
HEPACAM2 HEPACAM family member 2 1.56438
PLAT plasminogen activator, tissue 1.55986
BSDC1 BSD domain containing 1 1.55814
GSTK1 glutathione S-transferase kappa 1 1.55529
FAM120B family with sequence similarity 120B 1.55306
SIN3B SIN3 transcription regulator family member B 1.5499
MORC4 MORC family CW-type zinc finger 4 1.54853
ANXA2P1 annexin A2 pseudogene 1 1.54678
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 1.54456
KRT18 keratin 18, type I 1.53812
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.53723
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.52911
PDE9A phosphodiesterase 9A 1.52244
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.51708
TBX3 T-box 3 1.51582
MARVELD1 MARVEL domain containing 1 1.51203
RABGGTA Rab geranylgeranyltransferase, alpha subunit 1.49461
RNF207 ring finger protein 207 1.49358
SIX1 SIX homeobox 1 1.49299
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.49064
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.48851
SPPL2B signal peptide peptidase like 2B 1.48786
AKAP8L A kinase (PRKA) anchor protein 8-like 1.48767
GPR137C G protein-coupled receptor 137C 1.48423
KRTAP3-1 keratin associated protein 3-1 1.48242
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.48234
NPAS2 neuronal PAS domain protein 2 1.47851
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.47623
KIAA0040 KIAA0040 1.47424
MRC2 mannose receptor, C type 2 1.47342
MVP major vault protein 1.46953
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.4582
DHRS12 dehydrogenase/reductase (SDR family) member 12 1.45765
COPG1 coatomer protein complex, subunit gamma 1 1.45684
HMOX1 heme oxygenase 1 1.45384
COQ4 coenzyme Q4 1.45308
FOSL1 FOS-like antigen 1 1.44677
FAM27E3 family with sequence similarity 27, member E3 1.43883
DAP death-associated protein 1.43417
VIM vimentin 1.43312
ADCY7 adenylate cyclase 7 1.43307
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 1.43246
MKNK1 MAP kinase interacting serine/threonine kinase 1 1.43118
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 1.42974
DNAH10 dynein, axonemal, heavy chain 10 1.42855
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 1.42692
PLXND1 plexin D1 1.42511
CLIC2 chloride intracellular channel 2 1.40121
TCF21 transcription factor 21 1.40004
MYOF myoferlin 1.39923
ENO3 enolase 3 (beta, muscle) 1.39626
AXIN2 axin 2 1.39591
MPRIP myosin phosphatase Rho interacting protein 1.39495
A4GALT alpha 1,4-galactosyltransferase 1.39268
CLCN6 chloride channel, voltage-sensitive 6 1.39195
PLCD3 phospholipase C, delta 3 1.39102
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.38674
PCED1A PC-esterase domain containing 1A 1.38377
SHB Src homology 2 domain containing adaptor protein B 1.38377
LENG8 leukocyte receptor cluster (LRC) member 8 1.38324
SEPN1 selenoprotein N, 1 1.37778
CTGF connective tissue growth factor 1.37746
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 1.37013
PML promyelocytic leukemia 1.36799
LHFP lipoma HMGIC fusion partner 1.3659
MSX1 msh homeobox 1 1.36253
NADSYN1 NAD synthetase 1 1.35554
MYD88 myeloid differentiation primary response 88 1.3508
ZNF800 zinc finger protein 800 1.35079
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 1.34818
S100A6 S100 calcium binding protein A6 1.34499
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 1.3439
RRBP1 ribosome binding protein 1 1.34231
TXLNA taxilin alpha 1.34001
ANXA2 annexin A2 1.33771
SPEN spen family transcriptional repressor 1.33135
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.3305
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 1.32878
FAM222B family with sequence similarity 222, member B 1.32775
MYO1C myosin IC 1.32431
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.32349
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 1.32051
WASF3 WAS protein family, member 3 1.31475
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.3143
JARID2 jumonji, AT rich interactive domain 2 1.31369
ZFP36L1 ZFP36 ring finger protein-like 1 1.31135
GATSL3 GATS protein-like 3 1.30736
FAM214B family with sequence similarity 214, member B 1.30697
CES2 carboxylesterase 2 1.30285
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 1.30228
LOXL2 lysyl oxidase-like 2 1.29755
BCL3 B-cell CLL/lymphoma 3 1.29732
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 1.29642
MOAP1 modulator of apoptosis 1 1.29614
AKAP14 A kinase (PRKA) anchor protein 14 1.29061
NCK2 NCK adaptor protein 2 1.28703
ALAS1 5'-aminolevulinate synthase 1 1.28619
S100A4 S100 calcium binding protein A4 1.28261
PER1 period circadian clock 1 1.282
RNF213 ring finger protein 213 1.28181
FHL2 four and a half LIM domains 2 1.28144
SCN2A sodium channel, voltage gated, type II alpha subunit 1.28001
WDR4 WD repeat domain 4 1.27883
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 1.2783
F3 coagulation factor III (thromboplastin, tissue factor) 1.27601
AHNAK AHNAK nucleoprotein 1.27539
NINL ninein-like 1.27247
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.27231
ULK3 unc-51 like kinase 3 1.26894
TMEM91 transmembrane protein 91 1.26256
CSTB cystatin B (stefin B) 1.25955
MSI2 musashi RNA-binding protein 2 1.25677
PLK2 polo-like kinase 2 1.25628
TM9SF1 transmembrane 9 superfamily member 1 1.25558
CTSD cathepsin D 1.25398
SNORA48 small nucleolar RNA, H/ACA box 48 1.25348
MED13L mediator complex subunit 13-like 1.25287
SLK STE20-like kinase 1.2527
SLC16A6 solute carrier family 16, member 6 1.25239
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 1.25129
ADAMTSL5 ADAMTS-like 5 1.24941
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 1.24763
ANXA6 annexin A6 1.24459
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.24267
DPRX divergent-paired related homeobox 1.24266
RFX6 regulatory factor X, 6 1.23737
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.23629

decreased expression

Symbol Name Standardized Value
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -4.11517
PAPL iron/zinc purple acid phosphatase-like protein -4.01697
TRIB1 tribbles pseudokinase 1 -3.93062
STRA13 stimulated by retinoic acid 13 -3.79694
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.71732
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) -3.62262
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) -3.40515
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -3.36964
BOD1 biorientation of chromosomes in cell division 1 -3.34745
ANKRD22 ankyrin repeat domain 22 -3.34278
PBX1 pre-B-cell leukemia homeobox 1 -3.23053
MED22 mediator complex subunit 22 -3.17745
SPTSSB serine palmitoyltransferase, small subunit B -3.14226
TMEM147 transmembrane protein 147 -3.14096
HIPK2 homeodomain interacting protein kinase 2 -3.10975
LAMP3 lysosomal-associated membrane protein 3 -3.04936
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -3.03534
FXN frataxin -3.00834
NFIB nuclear factor I/B -2.96419
STK39 serine threonine kinase 39 -2.93206
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -2.84985
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d -2.83512
FEM1B fem-1 homolog b (C. elegans) -2.80125
TMEM50A transmembrane protein 50A -2.7848
ZBTB40 zinc finger and BTB domain containing 40 -2.76756
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.7669
FAM107B family with sequence similarity 107, member B -2.73887
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -2.72355
MED30 mediator complex subunit 30 -2.69914
CSN1S2AP casein alpha s2-like A, pseudogene -2.64172
MAPK13 mitogen-activated protein kinase 13 -2.61717
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.61683
ACVR1C activin A receptor, type IC -2.61157
ARRB2 arrestin, beta 2 -2.6075
MPI mannose phosphate isomerase -2.60235
RPUSD3 RNA pseudouridylate synthase domain containing 3 -2.57726
MPST mercaptopyruvate sulfurtransferase -2.54306
NPC2 Niemann-Pick disease, type C2 -2.51124
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) -2.50742
PRPF8 pre-mRNA processing factor 8 -2.49877
DUSP5 dual specificity phosphatase 5 -2.47256
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -2.44567
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -2.43694
ZNF268 zinc finger protein 268 -2.40934
LRRC1 leucine rich repeat containing 1 -2.37513
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.34376
EIF3G eukaryotic translation initiation factor 3, subunit G -2.34338
AJUBA ajuba LIM protein -2.33926
GRHL2 grainyhead-like 2 (Drosophila) -2.27912
SCNN1A sodium channel, non voltage gated 1 alpha subunit -2.27406
RBBP7 retinoblastoma binding protein 7 -2.27051
VAMP7 vesicle-associated membrane protein 7 -2.24658
GOLT1A golgi transport 1A -2.23243
EBF2 early B-cell factor 2 -2.21831
FAM101B family with sequence similarity 101, member B -2.21028
HOXA1 homeobox A1 -2.19522
OSBPL5 oxysterol binding protein-like 5 -2.17482
MYH15 myosin, heavy chain 15 -2.17143
CNTNAP1 contactin associated protein 1 -2.16641
STX3 syntaxin 3 -2.16526
EXOSC10 exosome component 10 -2.15705
LYN LYN proto-oncogene, Src family tyrosine kinase -2.13589
CAV2 caveolin 2 -2.10433
TES testin LIM domain protein -2.10286
AFF4 AF4/FMR2 family, member 4 -2.09249
SH3BP1 SH3-domain binding protein 1 -2.09078
GGCT gamma-glutamylcyclotransferase -2.08434
HDAC1 histone deacetylase 1 -2.07908
FSD1 fibronectin type III and SPRY domain containing 1 -2.06203
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -2.05402
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.05027
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.04933
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.04716
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -2.03546
UNC13A unc-13 homolog A (C. elegans) -2.0025
CACUL1 CDK2-associated, cullin domain 1 -1.99194
GAS6 growth arrest-specific 6 -1.98976
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -1.97698
EPN1 epsin 1 -1.95337
C1ORF174 chromosome 1 open reading frame 174 -1.9447
CCBL1 cysteine conjugate-beta lyase, cytoplasmic -1.9279
PNPLA2 patatin-like phospholipase domain containing 2 -1.91542
PPP6R3 protein phosphatase 6, regulatory subunit 3 -1.90784
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 -1.90132
H1F0 H1 histone family, member 0 -1.89799
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -1.89218
BRPF3 bromodomain and PHD finger containing, 3 -1.88479
STARD7 StAR-related lipid transfer (START) domain containing 7 -1.88127
RPS5 ribosomal protein S5 -1.87923
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.87771
BSPRY B-box and SPRY domain containing -1.87134
TMEM102 transmembrane protein 102 -1.86712
PRSS8 protease, serine, 8 -1.85987
KLHL12 kelch-like family member 12 -1.85327
FBXO25 F-box protein 25 -1.84554
TP73 tumor protein p73 -1.83775
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -1.82201
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -1.82127
CTC1 CTS telomere maintenance complex component 1 -1.8194
BCL7B B-cell CLL/lymphoma 7B -1.8026
YIPF2 Yip1 domain family, member 2 -1.79885
C19ORF48 chromosome 19 open reading frame 48 -1.79123
C19ORF53 chromosome 19 open reading frame 53 -1.78928
LAPTM4B lysosomal protein transmembrane 4 beta -1.77297
ZNF691 zinc finger protein 691 -1.77244
CKS1B CDC28 protein kinase regulatory subunit 1B -1.77188
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -1.76535
CA12 carbonic anhydrase XII -1.7627
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -1.76106
SMS spermine synthase -1.76001
SEPP1 selenoprotein P, plasma, 1 -1.75525
ERP29 endoplasmic reticulum protein 29 -1.7539
MIR153-1 microRNA 153-1 -1.75336
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -1.75232
TMEM258 transmembrane protein 258 -1.7504
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.74936
MPZL3 myelin protein zero-like 3 -1.74803
TSPAN18 tetraspanin 18 -1.74013
SOX4 SRY (sex determining region Y)-box 4 -1.73099
TTC39A tetratricopeptide repeat domain 39A -1.73097
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.72528
ZNF283 zinc finger protein 283 -1.72166
EPAS1 endothelial PAS domain protein 1 -1.71663
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -1.71619
SRSF9 serine/arginine-rich splicing factor 9 -1.71614
MCM4 minichromosome maintenance complex component 4 -1.70661
TMEM156 transmembrane protein 156 -1.70621
CHMP4B charged multivesicular body protein 4B -1.70133
TPGS2 tubulin polyglutamylase complex subunit 2 -1.70091
DCXR dicarbonyl/L-xylulose reductase -1.69109
KARS lysyl-tRNA synthetase -1.69077
WDR34 WD repeat domain 34 -1.69042
ZFP36 ZFP36 ring finger protein -1.68773
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) -1.68538
SUN2 Sad1 and UNC84 domain containing 2 -1.67599
WASF2 WAS protein family, member 2 -1.67533
MRPL51 mitochondrial ribosomal protein L51 -1.67141
ATP5SL ATP5S-like -1.67017
PMF1 polyamine-modulated factor 1 -1.66706
DCAF12 DDB1 and CUL4 associated factor 12 -1.66417
EPHA1 EPH receptor A1 -1.65877
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 -1.65811
ARTN artemin -1.65238
PLTP phospholipid transfer protein -1.64493
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -1.64359
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 -1.64306
PARD6B par-6 family cell polarity regulator beta -1.6387
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -1.63383
MEST mesoderm specific transcript -1.63376
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa -1.63284
PVR poliovirus receptor -1.63111
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.61989
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -1.60687
POTEA POTE ankyrin domain family, member A -1.60236
RAET1E retinoic acid early transcript 1E -1.59468
MAPK3 mitogen-activated protein kinase 3 -1.58937
NR5A2 nuclear receptor subfamily 5, group A, member 2 -1.58891
TRIM66 tripartite motif containing 66 -1.58563
BTBD2 BTB (POZ) domain containing 2 -1.58316
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -1.5817
KLK10 kallikrein-related peptidase 10 -1.57994
FAM83D family with sequence similarity 83, member D -1.56783
PAIP2B poly(A) binding protein interacting protein 2B -1.55731
CAV1 caveolin 1, caveolae protein, 22kDa -1.55451
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -1.55307
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -1.55136
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -1.54634
MT1F metallothionein 1F -1.54544
MID1IP1 MID1 interacting protein 1 -1.54473
NLE1 notchless homolog 1 (Drosophila) -1.54433
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.54362
ARID5B AT rich interactive domain 5B (MRF1-like) -1.53486
CORO6 coronin 6 -1.53367
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -1.5263
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -1.51995
RPS18 ribosomal protein S18 -1.51598
ARMC4 armadillo repeat containing 4 -1.51059
CLPTM1 cleft lip and palate associated transmembrane protein 1 -1.5103
ANXA10 annexin A10 -1.50817
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -1.49406
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.49213
TMEM97 transmembrane protein 97 -1.48072
ACTG1 actin gamma 1 -1.4803
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -1.47553
CFAP58 cilia and flagella associated protein 58 -1.47498
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -1.47251
IER3 immediate early response 3 -1.47086
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -1.46977
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -1.46334
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.45792
REEP2 receptor accessory protein 2 -1.45555
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -1.45201
HDDC2 HD domain containing 2 -1.45125
MAP7 microtubule-associated protein 7 -1.4512
FAM167A family with sequence similarity 167, member A -1.44948
MKX mohawk homeobox -1.44215
SPRED2 sprouty-related, EVH1 domain containing 2 -1.44166
ATXN7L3B ataxin 7-like 3B -1.44061
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) -1.4379
DACT1 dishevelled-binding antagonist of beta-catenin 1 -1.43417
MREG melanoregulin -1.43207
DAZAP1 DAZ associated protein 1 -1.4293
NGFR nerve growth factor receptor -1.4245
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -1.42371
SPOP speckle-type POZ protein -1.42242
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -1.42139
TMEM180 transmembrane protein 180 -1.42108
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit -1.41879
C6ORF99 chromosome 6 open reading frame 99 -1.41268
MACC1 metastasis associated in colon cancer 1 -1.41087
AMPD3 adenosine monophosphate deaminase 3 -1.40367
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.40201
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -1.40092
KSR2 kinase suppressor of ras 2 -1.39762
ADGRE2 adhesion G protein-coupled receptor E2 -1.38929
UBALD2 UBA-like domain containing 2 -1.38594
LSM12 LSM12 homolog (S. cerevisiae) -1.38223
CCAR2 cell cycle and apoptosis regulator 2 -1.38003
AIM1 absent in melanoma 1 -1.37624
TMCO4 transmembrane and coiled-coil domains 4 -1.37495
DOT1L DOT1-like histone H3K79 methyltransferase -1.37319
CTIF CBP80/20-dependent translation initiation factor -1.37225
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -1.37083
LIMA1 LIM domain and actin binding 1 -1.36756
BRD7P3 bromodomain containing 7 pseudogene 3 -1.36663
OLFM2 olfactomedin 2 -1.35226
GDI2 GDP dissociation inhibitor 2 -1.35143
LINGO1 leucine rich repeat and Ig domain containing 1 -1.35056
AREG amphiregulin -1.34899
KDF1 keratinocyte differentiation factor 1 -1.34809
RFC5 replication factor C (activator 1) 5, 36.5kDa -1.34673
SCLY selenocysteine lyase -1.34554
OR2B3 olfactory receptor, family 2, subfamily B, member 3 -1.34131
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1 -1.33837
TCOF1 Treacher Collins-Franceschetti syndrome 1 -1.33752
AURKB aurora kinase B -1.3366
LIMK1 LIM domain kinase 1 -1.33376
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) -1.33071
PALLD palladin, cytoskeletal associated protein -1.32894
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) -1.32862
JUP junction plakoglobin -1.32506
ACVR1B activin A receptor, type IB -1.3231
CPM carboxypeptidase M -1.31995
MRPS24 mitochondrial ribosomal protein S24 -1.31872
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -1.31814
GSK3A glycogen synthase kinase 3 alpha -1.31722
STOM stomatin -1.31699
DCAF13 DDB1 and CUL4 associated factor 13 -1.30548
WBSCR22 Williams Beuren syndrome chromosome region 22 -1.30503
JUNB jun B proto-oncogene -1.29673
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -1.2828
SWAP70 SWAP switching B-cell complex 70kDa subunit -1.28262
CRACR2A calcium release activated channel regulator 2A -1.28128
ZNF57 zinc finger protein 57 -1.28019
CARM1 coactivator-associated arginine methyltransferase 1 -1.27829
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -1.27262
USB1 U6 snRNA biogenesis 1 -1.27013
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -1.26847
FLNC filamin C, gamma -1.26681
TFRC transferrin receptor -1.26524
ZSWIM1 zinc finger, SWIM-type containing 1 -1.26521
GPRC5B G protein-coupled receptor, class C, group 5, member B -1.26394
ANKRD13B ankyrin repeat domain 13B -1.2632
H2AFX H2A histone family, member X -1.26091
CHAF1A chromatin assembly factor 1, subunit A (p150) -1.25695
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 -1.25424
EGLN3 egl-9 family hypoxia-inducible factor 3 -1.2483
F2RL2 coagulation factor II (thrombin) receptor-like 2 -1.24807
PAAF1 proteasomal ATPase-associated factor 1 -1.24663
CXXC5 CXXC finger protein 5 -1.24426
MCMBP minichromosome maintenance complex binding protein -1.24217
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -1.24189
UCA1 urothelial cancer associated 1 (non-protein coding) -1.23939
OLFML2B olfactomedin-like 2B -1.23211
TRIM14 tripartite motif containing 14 -1.23046
AP1M2 adaptor-related protein complex 1, mu 2 subunit -1.22316
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -1.2215
IRX4 iroquois homeobox 4 -1.22134
RPS13 ribosomal protein S13 -1.22113
PWP1 PWP1 homolog (S. cerevisiae) -1.22106
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -1.22085
HCFC1 host cell factor C1 -1.21511
FAM198B family with sequence similarity 198, member B -1.21315
ADM adrenomedullin -1.21299
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -1.2127
MTMR4 myotubularin related protein 4 -1.21229
CHD3 chromodomain helicase DNA binding protein 3 -1.21141
NOLC1 nucleolar and coiled-body phosphoprotein 1 -1.20769
KLHDC4 kelch domain containing 4 -1.20242
CDA cytidine deaminase -1.19896
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -1.19867
OSBPL10 oxysterol binding protein-like 10 -1.19589
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -1.19478
RAB11B RAB11B, member RAS oncogene family -1.19316
PHF21A PHD finger protein 21A -1.18998
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -1.18932
RHOA ras homolog family member A -1.18377
ANKRD40 ankyrin repeat domain 40 -1.18317
HDGFRP2 hepatoma-derived growth factor-related protein 2 -1.18099
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -1.17754