CDK8_knockdown_163_GSE38061 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38061
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Genes

600 genes differentially expressed following the CDK8_knockdown_163_GSE38061 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
BMP4 bone morphogenetic protein 4 4.40767
ZNF827 zinc finger protein 827 4.09177
C1ORF21 chromosome 1 open reading frame 21 3.40009
TTC19 tetratricopeptide repeat domain 19 2.98035
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.46206
FLOT2 flotillin 2 2.43214
ADGRF1 adhesion G protein-coupled receptor F1 2.40669
ARSJ arylsulfatase family, member J 2.40053
RNF43 ring finger protein 43 2.36669
MSX1 msh homeobox 1 2.29507
ZNF608 zinc finger protein 608 2.21268
DOCK4 dedicator of cytokinesis 4 2.17584
PLEKHN1 pleckstrin homology domain containing, family N member 1 2.095
LUC7L LUC7-like (S. cerevisiae) 2.0197
FABP6 fatty acid binding protein 6, ileal 1.96242
HRK harakiri, BCL2 interacting protein 1.85601
AGO1 argonaute RISC catalytic component 1 1.79851
TBP TATA box binding protein 1.79309
CRAT carnitine O-acetyltransferase 1.71061
PXDN peroxidasin 1.63875
ZNF595 zinc finger protein 595 1.63862
EHBP1 EH domain binding protein 1 1.59167
JARID2 jumonji, AT rich interactive domain 2 1.53621
STK10 serine/threonine kinase 10 1.53133
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.5126
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.51107
CAMK2D calcium/calmodulin-dependent protein kinase II delta 1.46856
F3 coagulation factor III (thromboplastin, tissue factor) 1.44422
ZNF358 zinc finger protein 358 1.43348
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.43244
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.42049
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 1.41517
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.40831
ARF6 ADP-ribosylation factor 6 1.4051
AKAP1 A kinase (PRKA) anchor protein 1 1.39907
NOL6 nucleolar protein 6 (RNA-associated) 1.3886
PLAU plasminogen activator, urokinase 1.38528
DGAT1 diacylglycerol O-acyltransferase 1 1.34621
MAGED1 melanoma antigen family D1 1.33472
DUSP4 dual specificity phosphatase 4 1.33406
TMEM263 transmembrane protein 263 1.33316
PVRL3 poliovirus receptor-related 3 1.28687
TNS4 tensin 4 1.27611
TRAPPC9 trafficking protein particle complex 9 1.27067
TMEM139 transmembrane protein 139 1.22379
DHRS3 dehydrogenase/reductase (SDR family) member 3 1.19242
FOXD1 forkhead box D1 1.18561
EEF2K eukaryotic elongation factor 2 kinase 1.172
MAP1B microtubule-associated protein 1B 1.16446
TUBGCP6 tubulin, gamma complex associated protein 6 1.15891
CD276 CD276 molecule 1.15652
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.14905
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 1.12704
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.11866
COQ9 coenzyme Q9 1.11656
TMSB4X thymosin beta 4, X-linked 1.10662
DPYSL2 dihydropyrimidinase-like 2 1.09847
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.09736
CALB2 calbindin 2 1.09594
TOMM34 translocase of outer mitochondrial membrane 34 1.09521
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.09262
TMTC4 transmembrane and tetratricopeptide repeat containing 4 1.08851
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.08226
CPT1A carnitine palmitoyltransferase 1A (liver) 1.07356
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 1.06959
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 1.06737
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.05381
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.05256
ZNF778 zinc finger protein 778 1.05117
ISM1 isthmin 1, angiogenesis inhibitor 1.04662
MBOAT2 membrane bound O-acyltransferase domain containing 2 1.03643
KRT8 keratin 8, type II 1.03424
EHD1 EH-domain containing 1 1.03108
ASB13 ankyrin repeat and SOCS box containing 13 1.0203
CPLX1 complexin 1 1.00551
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.00508
CASZ1 castor zinc finger 1 1.00473
HM13 histocompatibility (minor) 13 1.00152
TTLL1 tubulin tyrosine ligase-like family member 1 0.996127
SMOX spermine oxidase 0.992107
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.990748
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.990373
TM4SF1 transmembrane 4 L six family member 1 0.985878
STRADA STE20-related kinase adaptor alpha 0.985478
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 0.984789
GDAP1 ganglioside induced differentiation associated protein 1 0.975541
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.970008
ANO1 anoctamin 1, calcium activated chloride channel 0.969848
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.969412
SATB2 SATB homeobox 2 0.964435
DSP desmoplakin 0.961784
ZBED4 zinc finger, BED-type containing 4 0.954383
DAPK1 death-associated protein kinase 1 0.953698
JAG1 jagged 1 0.951804
CD44 CD44 molecule (Indian blood group) 0.949502
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.947512
CDC123 cell division cycle 123 0.942168
HIP1 huntingtin interacting protein 1 0.939482
FARSA phenylalanyl-tRNA synthetase, alpha subunit 0.935242
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 0.917225
MLKL mixed lineage kinase domain-like 0.912648
ZNF365 zinc finger protein 365 0.899681
STX10 syntaxin 10 0.895357
TPM4 tropomyosin 4 0.894282
FOSL1 FOS-like antigen 1 0.892675
PPP1R18 protein phosphatase 1, regulatory subunit 18 0.885082
LRRC41 leucine rich repeat containing 41 0.880695
SHROOM1 shroom family member 1 0.877494
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.871431
ACTN4 actinin, alpha 4 0.871285
ADAM19 ADAM metallopeptidase domain 19 0.870946
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.868097
KNOP1 lysine-rich nucleolar protein 1 0.868036
EHF ets homologous factor 0.865201
FOXA1 forkhead box A1 0.86389
KLF6 Kruppel-like factor 6 0.852181
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.850891
GRHL3 grainyhead-like 3 (Drosophila) 0.850488
OR4A47 olfactory receptor, family 4, subfamily A, member 47 0.84858
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.84322
IFI35 interferon-induced protein 35 0.842028
PTPRJ protein tyrosine phosphatase, receptor type, J 0.841745
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 0.835353
PYGB phosphorylase, glycogen; brain 0.827685
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.822932
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.822664
KIAA0040 KIAA0040 0.820889
LPP LIM domain containing preferred translocation partner in lipoma 0.819919
SUSD1 sushi domain containing 1 0.81923
SIGLEC9 sialic acid binding Ig-like lectin 9 0.818879
ADCY7 adenylate cyclase 7 0.817354
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.816749
ZFPL1 zinc finger protein-like 1 0.816715
C7ORF49 chromosome 7 open reading frame 49 0.813846
MED15 mediator complex subunit 15 0.812403
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.810716
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.807974
TCN2 transcobalamin II 0.802197
YLPM1 YLP motif containing 1 0.797134
CHN2 chimerin 2 0.796539
CENPV centromere protein V 0.795731
HEBP2 heme binding protein 2 0.791631
MRAS muscle RAS oncogene homolog 0.791274
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.789865
CNTNAP3 contactin associated protein-like 3 0.788066
PNPO pyridoxamine 5'-phosphate oxidase 0.786761
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.786553
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.780709
MAML3 mastermind-like 3 (Drosophila) 0.779949
TRABD TraB domain containing 0.778164
SNX30 sorting nexin family member 30 0.777668
RAP1GAP2 RAP1 GTPase activating protein 2 0.777044
IRS1 insulin receptor substrate 1 0.775026
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.772703
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.772116
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.771137
ACTBL2 actin, beta-like 2 0.768628
RNF4 ring finger protein 4 0.767008
NUDT16P1 nudix (nucleoside diphosphate linked moiety X)-type motif 16 pseudogene 1 0.762767
KDM1A lysine (K)-specific demethylase 1A 0.759325
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.755756
NOP2 NOP2 nucleolar protein 0.753577
ANXA6 annexin A6 0.749846
KLF10 Kruppel-like factor 10 0.748601
VAT1 vesicle amine transport 1 0.748146
ZBTB14 zinc finger and BTB domain containing 14 0.746675
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.744684
FERMT1 fermitin family member 1 0.743676
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.740092
ERCC2 excision repair cross-complementation group 2 0.738126
USP36 ubiquitin specific peptidase 36 0.735447
TRIOBP TRIO and F-actin binding protein 0.734783
ATHL1 ATH1, acid trehalase-like 1 (yeast) 0.732193
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.73135
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.731025
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 0.730241
DPYSL3 dihydropyrimidinase-like 3 0.728189
AGA aspartylglucosaminidase 0.726762
AMIGO2 adhesion molecule with Ig-like domain 2 0.724521
GRAMD2 GRAM domain containing 2 0.723517
FA2H fatty acid 2-hydroxylase 0.722162
LRRC23 leucine rich repeat containing 23 0.719617
NAV2 neuron navigator 2 0.719538
LARP4B La ribonucleoprotein domain family, member 4B 0.71742
FAM65A family with sequence similarity 65, member A 0.717215
GAL galanin/GMAP prepropeptide 0.714488
MAMLD1 mastermind-like domain containing 1 0.714195
BID BH3 interacting domain death agonist 0.711665
PCIF1 PDX1 C-terminal inhibiting factor 1 0.705515
ZNF627 zinc finger protein 627 0.705225
MFSD3 major facilitator superfamily domain containing 3 0.704518
CCDC88A coiled-coil domain containing 88A 0.704334
GYG1 glycogenin 1 0.704235
SLC16A9 solute carrier family 16, member 9 0.701505
CUEDC1 CUE domain containing 1 0.700808
KCTD13 potassium channel tetramerization domain containing 13 0.700547
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.699714
CAPRIN1 cell cycle associated protein 1 0.696961
ITGB4 integrin, beta 4 0.691131
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.691032
ZFP36L1 ZFP36 ring finger protein-like 1 0.688323
ANAPC7 anaphase promoting complex subunit 7 0.686736
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.685651
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.681628
MVP major vault protein 0.681305
FAM171A2 family with sequence similarity 171, member A2 0.679838
CCDC167 coiled-coil domain containing 167 0.678481
BLVRA biliverdin reductase A 0.678069
RNF31 ring finger protein 31 0.677543
BAMBI BMP and activin membrane-bound inhibitor 0.674537
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 0.672712
NCEH1 neutral cholesterol ester hydrolase 1 0.671982
TMEM133 transmembrane protein 133 0.671277
BCL2 B-cell CLL/lymphoma 2 0.671208
NTN4 netrin 4 0.661403
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.658755
PDCD5 programmed cell death 5 0.657378
UCK2 uridine-cytidine kinase 2 0.656818
CREB5 cAMP responsive element binding protein 5 0.656309
ZFYVE26 zinc finger, FYVE domain containing 26 0.655674
ASRGL1 asparaginase like 1 0.651379
NREP neuronal regeneration related protein 0.650109
TOM1L2 target of myb1-like 2 (chicken) 0.650058
ZMYND8 zinc finger, MYND-type containing 8 0.649794
ZNF837 zinc finger protein 837 0.649225
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.64896
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.647981
GSTK1 glutathione S-transferase kappa 1 0.647267
GAB2 GRB2-associated binding protein 2 0.646796
NEIL2 nei endonuclease VIII-like 2 (E. coli) 0.644508
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.643384
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.64268
APOL2 apolipoprotein L, 2 0.642539
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.641764
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.640454
AHNAK2 AHNAK nucleoprotein 2 0.639496
TESC tescalcin 0.635941
FAM57A family with sequence similarity 57, member A 0.635791
WFS1 Wolfram syndrome 1 (wolframin) 0.633821
CCNJL cyclin J-like 0.633312
LAMB1 laminin, beta 1 0.632935
CHDH choline dehydrogenase 0.632615
SRPR signal recognition particle receptor (docking protein) 0.630793
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.629115
NOSTRIN nitric oxide synthase trafficking 0.628171
CFAP97 cilia and flagella associated protein 97 0.628006
LRRN4 leucine rich repeat neuronal 4 0.626806
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.625455
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.624712
ACOXL acyl-CoA oxidase-like 0.624688
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 0.62328
SIGMAR1 sigma non-opioid intracellular receptor 1 0.622458
S100P S100 calcium binding protein P 0.622312
RHOB ras homolog family member B 0.620845
DSC2 desmocollin 2 0.620625
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 0.620622
REPS2 RALBP1 associated Eps domain containing 2 0.620324
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.618377
NCKAP1L NCK-associated protein 1-like 0.61609
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.61586
AFAP1L1 actin filament associated protein 1-like 1 0.613557
EFNB2 ephrin-B2 0.612991
SAMM50 SAMM50 sorting and assembly machinery component 0.612563
CAT catalase 0.612329
RAB3D RAB3D, member RAS oncogene family 0.608475
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.608269
ATP9A ATPase, class II, type 9A 0.607188
CKAP4 cytoskeleton-associated protein 4 0.603198
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.602552
RYR1 ryanodine receptor 1 (skeletal) 0.602506
EPHA10 EPH receptor A10 0.60206
DENND2D DENN/MADD domain containing 2D 0.599502
ISYNA1 inositol-3-phosphate synthase 1 0.598135
MAST2 microtubule associated serine/threonine kinase 2 0.598008
ANTXR2 anthrax toxin receptor 2 0.597641
RTTN rotatin 0.597267
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.596966
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.596899
ERVMER34-1 endogenous retrovirus group MER34, member 1 0.596458
TMEM38A transmembrane protein 38A 0.595695
RNASEH2A ribonuclease H2, subunit A 0.595675
CPNE2 copine II 0.595662
ARHGAP17 Rho GTPase activating protein 17 0.595544
MYOM1 myomesin 1 0.594632
TMCO6 transmembrane and coiled-coil domains 6 0.592695
WNT16 wingless-type MMTV integration site family, member 16 0.590437
GEMIN5 gem (nuclear organelle) associated protein 5 0.589596
PITRM1 pitrilysin metallopeptidase 1 0.586788
RREB1 ras responsive element binding protein 1 0.583494
RFWD3 ring finger and WD repeat domain 3 0.583345
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.583231
JPH1 junctophilin 1 0.583074
TTC37 tetratricopeptide repeat domain 37 0.580137
PLXNA1 plexin A1 0.580092
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.579504
WDTC1 WD and tetratricopeptide repeats 1 0.57753
PLK2 polo-like kinase 2 0.577173
CLTCL1 clathrin, heavy chain-like 1 0.576526
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.575578
RWDD2A RWD domain containing 2A 0.575223

decreased expression

Symbol Name Standardized Value
OR51B4 olfactory receptor, family 51, subfamily B, member 4 -5.51085
ETV1 ets variant 1 -3.31741
SQLE squalene epoxidase -3.25976
GLMP glycosylated lysosomal membrane protein -3.11431
TRAFD1 TRAF-type zinc finger domain containing 1 -2.73701
MET MET proto-oncogene, receptor tyrosine kinase -2.63901
CLDN4 claudin 4 -2.49188
MT1DP metallothionein 1D, pseudogene (functional) -2.46012
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.44475
VDAC3 voltage-dependent anion channel 3 -2.43778
TBC1D19 TBC1 domain family, member 19 -2.15759
STOM stomatin -1.77805
SCNN1A sodium channel, non voltage gated 1 alpha subunit -1.72753
GRHL2 grainyhead-like 2 (Drosophila) -1.67947
TIMP1 TIMP metallopeptidase inhibitor 1 -1.63279
MT1G metallothionein 1G -1.59872
RBM23 RNA binding motif protein 23 -1.59073
AFF4 AF4/FMR2 family, member 4 -1.57841
NFIB nuclear factor I/B -1.54505
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -1.54231
SLC22A20 solute carrier family 22, member 20 -1.52947
GCC1 GRIP and coiled-coil domain containing 1 -1.50573
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -1.48415
HIST1H3E histone cluster 1, H3e -1.47148
RNF11 ring finger protein 11 -1.45857
GSTZ1 glutathione S-transferase zeta 1 -1.40083
MT2A metallothionein 2A -1.39527
BSG basigin (Ok blood group) -1.37243
KCTD11 potassium channel tetramerization domain containing 11 -1.37051
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -1.33933
IFI30 interferon, gamma-inducible protein 30 -1.32551
SRPRB signal recognition particle receptor, B subunit -1.31981
TMEM165 transmembrane protein 165 -1.29325
SGMS2 sphingomyelin synthase 2 -1.28907
SYTL3 synaptotagmin-like 3 -1.28379
TM2D1 TM2 domain containing 1 -1.275
TACSTD2 tumor-associated calcium signal transducer 2 -1.26999
PRSS8 protease, serine, 8 -1.25212
AGBL5 ATP/GTP binding protein-like 5 -1.2499
NR2F1 nuclear receptor subfamily 2, group F, member 1 -1.24953
CLIP1 CAP-GLY domain containing linker protein 1 -1.22575
PRAF2 PRA1 domain family, member 2 -1.19981
SCPEP1 serine carboxypeptidase 1 -1.19391
CLDN7 claudin 7 -1.19004
ANTXR1 anthrax toxin receptor 1 -1.18408
EPN3 epsin 3 -1.17629
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.17098
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -1.1704
LAT linker for activation of T cells -1.16753
ZNF329 zinc finger protein 329 -1.1434
RYBP RING1 and YY1 binding protein -1.14311
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.13073
MBOAT1 membrane bound O-acyltransferase domain containing 1 -1.10666
LIMA1 LIM domain and actin binding 1 -1.10506
TIMP2 TIMP metallopeptidase inhibitor 2 -1.10004
RGS2 regulator of G-protein signaling 2 -1.09798
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -1.09021
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -1.08761
ADIPOR1 adiponectin receptor 1 -1.08564
C14ORF1 chromosome 14 open reading frame 1 -1.08532
FADS1 fatty acid desaturase 1 -1.08327
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -1.08297
SERTAD2 SERTA domain containing 2 -1.08191
CPA4 carboxypeptidase A4 -1.07197
FAM43A family with sequence similarity 43, member A -1.062
LPIN1 lipin 1 -1.0556
WDR45B WD repeat domain 45B -1.05275
CNN3 calponin 3, acidic -1.04228
NRP1 neuropilin 1 -1.0315
NQO1 NAD(P)H dehydrogenase, quinone 1 -1.0295
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -1.02624
FN3K fructosamine 3 kinase -1.0251
BRPF3 bromodomain and PHD finger containing, 3 -1.02182
FAM53C family with sequence similarity 53, member C -1.02137
ZDHHC16 zinc finger, DHHC-type containing 16 -1.01321
HIGD2A HIG1 hypoxia inducible domain family, member 2A -1.01321
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.00694
ZNF266 zinc finger protein 266 -1.00374
SREBF1 sterol regulatory element binding transcription factor 1 -1.0021
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) -0.989054
CGN cingulin -0.982519
AP3M2 adaptor-related protein complex 3, mu 2 subunit -0.96301
TRAM2 translocation associated membrane protein 2 -0.960637
CSRP1 cysteine and glycine-rich protein 1 -0.950734
MEF2C myocyte enhancer factor 2C -0.943014
ZNF99 zinc finger protein 99 -0.936031
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -0.930515
TGM2 transglutaminase 2 -0.913357
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.905685
USP30 ubiquitin specific peptidase 30 -0.905325
ADGRB2 adhesion G protein-coupled receptor B2 -0.903197
PHACTR4 phosphatase and actin regulator 4 -0.902342
BIRC6 baculoviral IAP repeat containing 6 -0.897556
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -0.888356
BRWD3 bromodomain and WD repeat domain containing 3 -0.878945
LAMP1 lysosomal-associated membrane protein 1 -0.874572
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.871393
INSIG1 insulin induced gene 1 -0.864318
CDA cytidine deaminase -0.860458
KLHDC3 kelch domain containing 3 -0.859101
FANCE Fanconi anemia, complementation group E -0.849776
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.848692
FOPNL FGFR1OP N-terminal like -0.843013
ADGRE2 adhesion G protein-coupled receptor E2 -0.832506
C16ORF45 chromosome 16 open reading frame 45 -0.831962
DNAAF3 dynein, axonemal, assembly factor 3 -0.828641
FXR1 fragile X mental retardation, autosomal homolog 1 -0.828334
RP2 retinitis pigmentosa 2 (X-linked recessive) -0.824726
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.824572
PROP1 PROP paired-like homeobox 1 -0.824115
TFRC transferrin receptor -0.816339
SHROOM3 shroom family member 3 -0.814833
PXK PX domain containing serine/threonine kinase -0.810668
LSM12 LSM12 homolog (S. cerevisiae) -0.805216
KIAA0895 KIAA0895 -0.80368
MRPL33 mitochondrial ribosomal protein L33 -0.803101
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.802259
FXYD3 FXYD domain containing ion transport regulator 3 -0.801305
KLK6 kallikrein-related peptidase 6 -0.799506
TSEN54 TSEN54 tRNA splicing endonuclease subunit -0.796516
NCAPD2 non-SMC condensin I complex, subunit D2 -0.793488
ADAP2 ArfGAP with dual PH domains 2 -0.792798
LETMD1 LETM1 domain containing 1 -0.790454
NUP188 nucleoporin 188kDa -0.790226
MKX mohawk homeobox -0.783464
MINPP1 multiple inositol-polyphosphate phosphatase 1 -0.781908
GPR22 G protein-coupled receptor 22 -0.778674
SDF4 stromal cell derived factor 4 -0.778364
OR5P3 olfactory receptor, family 5, subfamily P, member 3 -0.777661
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -0.776023
PDIA4 protein disulfide isomerase family A, member 4 -0.775643
MRC1 mannose receptor, C type 1 -0.774041
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -0.767531
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -0.765922
TRIP10 thyroid hormone receptor interactor 10 -0.76535
SERINC3 serine incorporator 3 -0.764545
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -0.759403
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.757241
CYB5A cytochrome b5 type A (microsomal) -0.755351
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -0.754844
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 -0.754749
AVPI1 arginine vasopressin-induced 1 -0.745991
FBXO21 F-box protein 21 -0.74505
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -0.744534
ICMT isoprenylcysteine carboxyl methyltransferase -0.743144
YARS tyrosyl-tRNA synthetase -0.741689
FTH1 ferritin, heavy polypeptide 1 -0.739036
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -0.736543
C10ORF67 chromosome 10 open reading frame 67 -0.736484
SLC44A2 solute carrier family 44 (choline transporter), member 2 -0.735318
RFC2 replication factor C (activator 1) 2, 40kDa -0.730944
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -0.72699
TMEM41B transmembrane protein 41B -0.722293
MBTD1 mbt domain containing 1 -0.71921
PPT1 palmitoyl-protein thioesterase 1 -0.718719
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.716704
FXR2 fragile X mental retardation, autosomal homolog 2 -0.715368
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.712631
BTN2A2 butyrophilin, subfamily 2, member A2 -0.710178
ATP11A ATPase, class VI, type 11A -0.70881
SHROOM2 shroom family member 2 -0.70827
FAM122B family with sequence similarity 122B -0.707256
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1 -0.702898
LDLR low density lipoprotein receptor -0.700493
MERTK MER proto-oncogene, tyrosine kinase -0.699114
DNAH2 dynein, axonemal, heavy chain 2 -0.699043
MFGE8 milk fat globule-EGF factor 8 protein -0.698213
MICB MHC class I polypeptide-related sequence B -0.697162
SPIN4 spindlin family, member 4 -0.695138
SNORA80E small nucleolar RNA, H/ACA box 80E -0.693833
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) -0.693608
CA11 carbonic anhydrase XI -0.692598
FOLR1 folate receptor 1 (adult) -0.691234
STX8 syntaxin 8 -0.689582
PARD6B par-6 family cell polarity regulator beta -0.688797
DBX2 developing brain homeobox 2 -0.681562
SIDT2 SID1 transmembrane family, member 2 -0.680522
NAP1L5 nucleosome assembly protein 1-like 5 -0.679289
TRIM2 tripartite motif containing 2 -0.679172
PAM peptidylglycine alpha-amidating monooxygenase -0.674065
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -0.673617
SPC24 SPC24, NDC80 kinetochore complex component -0.673541
FLNC filamin C, gamma -0.672455
EPHA1 EPH receptor A1 -0.671328
FAM98C family with sequence similarity 98, member C -0.665836
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.665237
SRP68 signal recognition particle 68kDa -0.664483
SP4 Sp4 transcription factor -0.662414
DSE dermatan sulfate epimerase -0.661789
PBX1 pre-B-cell leukemia homeobox 1 -0.661255
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -0.65994
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.659836
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.657915
TMEM55A transmembrane protein 55A -0.656122
ALOXE3 arachidonate lipoxygenase 3 -0.649459
SPTSSB serine palmitoyltransferase, small subunit B -0.643772
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.642951
TMEM205 transmembrane protein 205 -0.64098
TM9SF2 transmembrane 9 superfamily member 2 -0.637944
SQSTM1 sequestosome 1 -0.637461
MXRA7 matrix-remodelling associated 7 -0.637205
KRT23 keratin 23, type I -0.63658
BTN3A1 butyrophilin, subfamily 3, member A1 -0.634778
LIPG lipase, endothelial -0.634065
FAF2 Fas associated factor family member 2 -0.631594
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -0.630901
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) -0.630504
NEURL1 neuralized E3 ubiquitin protein ligase 1 -0.626066
PRDM10 PR domain containing 10 -0.62459
PCNX pecanex homolog (Drosophila) -0.624559
TPD52L1 tumor protein D52-like 1 -0.62388
KPNB1 karyopherin (importin) beta 1 -0.618625
SNX5 sorting nexin 5 -0.61793
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -0.617706
HIAT1 hippocampus abundant transcript 1 -0.617565
CDC26 cell division cycle 26 -0.617504
TRIB1 tribbles pseudokinase 1 -0.615268
HIST2H2BE histone cluster 2, H2be -0.614242
TMX2 thioredoxin-related transmembrane protein 2 -0.610891
FRRS1 ferric-chelate reductase 1 -0.610237
ZCCHC8 zinc finger, CCHC domain containing 8 -0.610035
MYO9A myosin IXA -0.609637
CLDN12 claudin 12 -0.608182
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.606457
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene -0.60595
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.605803
HLA-B major histocompatibility complex, class I, B -0.603931
BEX4 brain expressed, X-linked 4 -0.603344
CC2D1B coiled-coil and C2 domain containing 1B -0.603006
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.601143
GDF15 growth differentiation factor 15 -0.599412
TRAPPC2L trafficking protein particle complex 2-like -0.598651
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -0.598266
SLC38A5 solute carrier family 38, member 5 -0.597781
PARP2 poly (ADP-ribose) polymerase 2 -0.597385
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.595655
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -0.594004
SELT selenoprotein T -0.592624
RPS6 ribosomal protein S6 -0.591606
HIST1H1E histone cluster 1, H1e -0.591162
PHF21A PHD finger protein 21A -0.590401
INSL3 insulin-like 3 (Leydig cell) -0.589735
FGF19 fibroblast growth factor 19 -0.588915
CRYAA crystallin, alpha A -0.586158
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -0.585688
IFITM1 interferon induced transmembrane protein 1 -0.584876
EGR1 early growth response 1 -0.584063
ERMN ermin, ERM-like protein -0.582358
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.582255
ABHD16A abhydrolase domain containing 16A -0.581272
MON2 MON2 homolog (S. cerevisiae) -0.58065
CALCOCO2 calcium binding and coiled-coil domain 2 -0.579719
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -0.578756
CD164 CD164 molecule, sialomucin -0.578492
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -0.577943
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -0.577675
NBR1 neighbor of BRCA1 gene 1 -0.577395
PFKM phosphofructokinase, muscle -0.57558
NUP62CL nucleoporin 62kDa C-terminal like -0.575405
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -0.575061
MROH2A maestro heat-like repeat family member 2A -0.574351
SUN2 Sad1 and UNC84 domain containing 2 -0.573928
RBM47 RNA binding motif protein 47 -0.573575
YIPF6 Yip1 domain family, member 6 -0.573176
HEXB hexosaminidase B (beta polypeptide) -0.570348
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C -0.569386
HDGFL1 hepatoma derived growth factor-like 1 -0.568141
ARNTL aryl hydrocarbon receptor nuclear translocator-like -0.566812
IQGAP1 IQ motif containing GTPase activating protein 1 -0.565147
ACLY ATP citrate lyase -0.564867
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) -0.563868
NT5E 5'-nucleotidase, ecto (CD73) -0.562562
ARHGAP18 Rho GTPase activating protein 18 -0.562379
SLC44A1 solute carrier family 44 (choline transporter), member 1 -0.561988
FBXO27 F-box protein 27 -0.561455
CIB2 calcium and integrin binding family member 2 -0.561167
EBP emopamil binding protein (sterol isomerase) -0.561121
UNC13A unc-13 homolog A (C. elegans) -0.559689
YBX1 Y box binding protein 1 -0.55944
CABS1 calcium-binding protein, spermatid-specific 1 -0.557654
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 -0.557494
STEAP2 STEAP family member 2, metalloreductase -0.557161
UCA1 urothelial cancer associated 1 (non-protein coding) -0.55675
MBNL1 muscleblind-like splicing regulator 1 -0.556525
PCSK9 proprotein convertase subtilisin/kexin type 9 -0.555861
DYNLL1 dynein, light chain, LC8-type 1 -0.554942
SPICE1 spindle and centriole associated protein 1 -0.554669
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.554311
DNASE2 deoxyribonuclease II, lysosomal -0.554041
PXMP2 peroxisomal membrane protein 2, 22kDa -0.553933
AIF1L allograft inflammatory factor 1-like -0.553839
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -0.553348
SYNGR1 synaptogyrin 1 -0.551922
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.550589
CD109 CD109 molecule -0.550407
G6PD glucose-6-phosphate dehydrogenase -0.549568
TMEM25 transmembrane protein 25 -0.549059
SNORA21 small nucleolar RNA, H/ACA box 21 -0.54887
ISCU iron-sulfur cluster assembly enzyme -0.548755
CAV2 caveolin 2 -0.548127