CDK8_knockdown_63_GSE19199 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE19199
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Genes

600 genes differentially expressed following the CDK8_knockdown_63_GSE19199 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 4.00473
RNF43 ring finger protein 43 3.78991
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 3.7343
MFAP2 microfibrillar-associated protein 2 3.4276
ANO1 anoctamin 1, calcium activated chloride channel 3.34466
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 3.08171
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 3.07239
PTDSS1 phosphatidylserine synthase 1 3.04205
TSHZ1 teashirt zinc finger homeobox 1 3.00693
AKAP12 A kinase (PRKA) anchor protein 12 2.96475
PSAP prosaposin 2.95387
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 2.92458
CDH3 cadherin 3, type 1, P-cadherin (placental) 2.90352
S100A10 S100 calcium binding protein A10 2.88317
RAB31 RAB31, member RAS oncogene family 2.8399
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.80304
ITGB4 integrin, beta 4 2.79222
SLC39A8 solute carrier family 39 (zinc transporter), member 8 2.76635
SH3D19 SH3 domain containing 19 2.7256
TM4SF18 transmembrane 4 L six family member 18 2.71255
KNOP1 lysine-rich nucleolar protein 1 2.7039
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 2.65667
DOCK1 dedicator of cytokinesis 1 2.6507
CAPN1 calpain 1, (mu/I) large subunit 2.6018
KRT18 keratin 18, type I 2.59825
SEZ6L2 seizure related 6 homolog (mouse)-like 2 2.59574
DHRS3 dehydrogenase/reductase (SDR family) member 3 2.589
CASC3 cancer susceptibility candidate 3 2.57752
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 2.56978
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.54391
SAV1 salvador family WW domain containing protein 1 2.53202
EZR ezrin 2.52698
TEAD2 TEA domain family member 2 2.51804
NFE2L1 nuclear factor, erythroid 2-like 1 2.42897
ARL2 ADP-ribosylation factor-like 2 2.41056
MYOF myoferlin 2.32268
SOX4 SRY (sex determining region Y)-box 4 2.30197
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.30107
CD276 CD276 molecule 2.27982
ZDHHC2 zinc finger, DHHC-type containing 2 2.27339
CD44 CD44 molecule (Indian blood group) 2.27225
G0S2 G0/G1 switch 2 2.2356
IL13RA1 interleukin 13 receptor, alpha 1 2.23376
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 2.22525
WLS wntless Wnt ligand secretion mediator 2.22134
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.20746
LAMC2 laminin, gamma 2 2.20645
ADAM9 ADAM metallopeptidase domain 9 2.18552
KRT8 keratin 8, type II 2.18037
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.17523
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 2.16934
ABR active BCR-related 2.15974
TNIK TRAF2 and NCK interacting kinase 2.15391
KIF1C kinesin family member 1C 2.1322
CNTNAP3 contactin associated protein-like 3 2.13012
TINAGL1 tubulointerstitial nephritis antigen-like 1 2.12689
AP2B1 adaptor-related protein complex 2, beta 1 subunit 2.12368
CERK ceramide kinase 2.10016
VAT1 vesicle amine transport 1 2.09909
TMC4 transmembrane channel-like 4 2.08461
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.07697
KIAA1551 KIAA1551 2.06796
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.06753
PKN1 protein kinase N1 2.05572
EFNB2 ephrin-B2 2.05319
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.02598
TMCO3 transmembrane and coiled-coil domains 3 2.0121
DPYSL2 dihydropyrimidinase-like 2 2.00261
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1.9964
ANXA2 annexin A2 1.98766
CD59 CD59 molecule, complement regulatory protein 1.98304
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.97901
BCL2L1 BCL2-like 1 1.97826
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 1.97631
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 1.97018
GRAMD1A GRAM domain containing 1A 1.9685
DDR1 discoidin domain receptor tyrosine kinase 1 1.96635
ADAM19 ADAM metallopeptidase domain 19 1.96337
TSPAN13 tetraspanin 13 1.95922
PPAP2B phosphatidic acid phosphatase type 2B 1.94988
NEBL nebulette 1.94804
TTC39C tetratricopeptide repeat domain 39C 1.9469
KIAA1462 KIAA1462 1.94526
MTUS1 microtubule associated tumor suppressor 1 1.9398
LIMS2 LIM and senescent cell antigen-like domains 2 1.93827
TSPAN14 tetraspanin 14 1.92738
GYLTL1B glycosyltransferase-like 1B 1.91318
TP53I3 tumor protein p53 inducible protein 3 1.90624
UFC1 ubiquitin-fold modifier conjugating enzyme 1 1.90621
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.89061
KLRC4 killer cell lectin-like receptor subfamily C, member 4 1.88318
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.87888
PDLIM5 PDZ and LIM domain 5 1.87459
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 1.85488
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.85419
PRDX5 peroxiredoxin 5 1.85257
MPRIP myosin phosphatase Rho interacting protein 1.84474
ANKIB1 ankyrin repeat and IBR domain containing 1 1.83922
ITGB5 integrin, beta 5 1.83768
HSPA1A heat shock 70kDa protein 1A 1.83195
EEF2K eukaryotic elongation factor 2 kinase 1.82664
BIK BCL2-interacting killer (apoptosis-inducing) 1.82649
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 1.82628
OLFM2 olfactomedin 2 1.82552
SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.81959
BZW2 basic leucine zipper and W2 domains 2 1.8091
SERINC1 serine incorporator 1 1.80621
FHOD3 formin homology 2 domain containing 3 1.8054
MXI1 MAX interactor 1, dimerization protein 1.80392
EIF3D eukaryotic translation initiation factor 3, subunit D 1.80311
TIGAR TP53 induced glycolysis regulatory phosphatase 1.8028
IL17RD interleukin 17 receptor D 1.8026
DOCK3 dedicator of cytokinesis 3 1.80151
HDAC9 histone deacetylase 9 1.79675
ANAPC16 anaphase promoting complex subunit 16 1.78221
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.77736
APP amyloid beta (A4) precursor protein 1.77078
WWC1 WW and C2 domain containing 1 1.76089
SCUBE1 signal peptide, CUB domain, EGF-like 1 1.76061
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 1.75401
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1.74663
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 1.74559
PITRM1 pitrilysin metallopeptidase 1 1.74166
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.73443
KIF26B kinesin family member 26B 1.73268
PARP3 poly (ADP-ribose) polymerase family, member 3 1.72515
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.72157
CUEDC2 CUE domain containing 2 1.71696
TMEM132A transmembrane protein 132A 1.71348
ANTXR2 anthrax toxin receptor 2 1.70549
HERPUD2 HERPUD family member 2 1.7006
FAM3C family with sequence similarity 3, member C 1.698
CD83 CD83 molecule 1.69411
FRMD5 FERM domain containing 5 1.68991
GRAMD4 GRAM domain containing 4 1.68872
TCF12 transcription factor 12 1.68476
CTSB cathepsin B 1.68181
NBEAL2 neurobeachin-like 2 1.68012
ACAD10 acyl-CoA dehydrogenase family, member 10 1.67551
FBXL2 F-box and leucine-rich repeat protein 2 1.67202
SIRT1 sirtuin 1 1.67021
TIAM1 T-cell lymphoma invasion and metastasis 1 1.66354
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.66276
DDB2 damage-specific DNA binding protein 2, 48kDa 1.66172
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.65838
ADGRF1 adhesion G protein-coupled receptor F1 1.65674
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.65665
HARS histidyl-tRNA synthetase 1.65325
GPR87 G protein-coupled receptor 87 1.64745
KIF5A kinesin family member 5A 1.63968
PHLDB2 pleckstrin homology-like domain, family B, member 2 1.63965
MYO9B myosin IXB 1.63209
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.6288
PREP prolyl endopeptidase 1.62376
PVRL3 poliovirus receptor-related 3 1.62291
RABL6 RAB, member RAS oncogene family-like 6 1.62227
DACT1 dishevelled-binding antagonist of beta-catenin 1 1.61674
H2AFY2 H2A histone family, member Y2 1.6145
RELT RELT tumor necrosis factor receptor 1.61144
PDCD6IP programmed cell death 6 interacting protein 1.60693
ATOX1 antioxidant 1 copper chaperone 1.60385
SPINT1 serine peptidase inhibitor, Kunitz type 1 1.59892
TMSB10 thymosin beta 10 1.59469
LITAF lipopolysaccharide-induced TNF factor 1.59334
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.58206
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 1.57717
CRY1 cryptochrome circadian clock 1 1.57341
LYPLA2 lysophospholipase II 1.57293
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.57078
CRYL1 crystallin, lambda 1 1.56891
SULF2 sulfatase 2 1.56607
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.56478
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.5625
TUBB tubulin, beta class I 1.56232
ARSG arylsulfatase G 1.56197
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 1.55748
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 1.5556
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) 1.54722
INF2 inverted formin, FH2 and WH2 domain containing 1.54698
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.54669
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.54631
CHKA choline kinase alpha 1.54441
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 1.54104
CABLES1 Cdk5 and Abl enzyme substrate 1 1.54059
JARID2 jumonji, AT rich interactive domain 2 1.53833
SERINC2 serine incorporator 2 1.53811
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 1.53587
AGRN agrin 1.52861
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.52508
CXCL16 chemokine (C-X-C motif) ligand 16 1.52053
NOL8 nucleolar protein 8 1.50948
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.50779
ACTN1 actinin, alpha 1 1.50061
CNPY3 canopy FGF signaling regulator 3 1.4902
CRIP2 cysteine-rich protein 2 1.48964
FAM117B family with sequence similarity 117, member B 1.48919
DDA1 DET1 and DDB1 associated 1 1.48884
CUEDC1 CUE domain containing 1 1.4877
MARVELD1 MARVEL domain containing 1 1.48683
ATP11C ATPase, class VI, type 11C 1.47961
SLC35E2 solute carrier family 35, member E2 1.47844
IST1 increased sodium tolerance 1 homolog (yeast) 1.47254
MEIS2 Meis homeobox 2 1.47227
CHPT1 choline phosphotransferase 1 1.46957
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 1.46857
DCTN1 dynactin 1 1.46535
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 1.46422
SPATS2L spermatogenesis associated, serine-rich 2-like 1.46137
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.46032
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.45959
RRAGA Ras-related GTP binding A 1.45903
ANXA1 annexin A1 1.45594
OGFRL1 opioid growth factor receptor-like 1 1.45324
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 1.4503
FAM102A family with sequence similarity 102, member A 1.44929
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.44645
FSCN1 fascin actin-bundling protein 1 1.44286
PPARG peroxisome proliferator-activated receptor gamma 1.44257
TMC5 transmembrane channel-like 5 1.44174
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.44149
GLB1L2 galactosidase, beta 1-like 2 1.43898
ANKRD10 ankyrin repeat domain 10 1.43708
FAM120B family with sequence similarity 120B 1.43506
ETV4 ets variant 4 1.43459
SLX4IP SLX4 interacting protein 1.43319
DRD1 dopamine receptor D1 1.42324
MCF2L MCF.2 cell line derived transforming sequence-like 1.41487
LAMB1 laminin, beta 1 1.4099
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.40974
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.40777
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head) 1.40017
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 1.39787
ARSJ arylsulfatase family, member J 1.39769
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.39651
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.39648
KLHL24 kelch-like family member 24 1.39627
RAB10 RAB10, member RAS oncogene family 1.38953
CAPN2 calpain 2, (m/II) large subunit 1.38775
ARHGAP12 Rho GTPase activating protein 12 1.38459
PRKD3 protein kinase D3 1.38323
LRRC8A leucine rich repeat containing 8 family, member A 1.37948
DCTN4 dynactin 4 (p62) 1.37843
COCH cochlin 1.37596
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.37478
PDLIM1 PDZ and LIM domain 1 1.37261
EEF2 eukaryotic translation elongation factor 2 1.37101
ANXA3 annexin A3 1.37063
DHCR24 24-dehydrocholesterol reductase 1.36965
AGPS alkylglycerone phosphate synthase 1.36916
ARL4C ADP-ribosylation factor-like 4C 1.36882
DPYSL3 dihydropyrimidinase-like 3 1.36299
TWF2 twinfilin actin binding protein 2 1.36239
TBRG4 transforming growth factor beta regulator 4 1.36228
NPNT nephronectin 1.36001
SBF1 SET binding factor 1 1.35286
HSF1 heat shock transcription factor 1 1.35072
F2R coagulation factor II (thrombin) receptor 1.34546
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.34309
UBAP2 ubiquitin associated protein 2 1.34146
YIPF3 Yip1 domain family, member 3 1.33906
ANXA6 annexin A6 1.33676
RALY RALY heterogeneous nuclear ribonucleoprotein 1.33517
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 1.33429
MARCH5 membrane-associated ring finger (C3HC4) 5 1.3314
COL18A1 collagen, type XVIII, alpha 1 1.33112
FASN fatty acid synthase 1.32884
MCAM melanoma cell adhesion molecule 1.32362
FYN FYN proto-oncogene, Src family tyrosine kinase 1.32231
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 1.32015
GM2A GM2 ganglioside activator 1.31894
AHCYL2 adenosylhomocysteinase-like 2 1.31808
PRDX6 peroxiredoxin 6 1.31801
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.31767
SOCS6 suppressor of cytokine signaling 6 1.31467
ASRGL1 asparaginase like 1 1.31277
PDE9A phosphodiesterase 9A 1.3126
CLIC4 chloride intracellular channel 4 1.31197
SMAD1 SMAD family member 1 1.30955
WWC2 WW and C2 domain containing 2 1.30654
PLXNB2 plexin B2 1.30598
DUSP6 dual specificity phosphatase 6 1.30491
PPAP2C phosphatidic acid phosphatase type 2C 1.30454
ERV3-1 endogenous retrovirus group 3, member 1 1.30221
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 1.30139
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 1.29831
ZFP64 ZFP64 zinc finger protein 1.29097
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.28934
PLLP plasmolipin 1.28832
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 1.28589
WDR1 WD repeat domain 1 1.28085
ZNF330 zinc finger protein 330 1.27898
IGSF3 immunoglobulin superfamily, member 3 1.2775
PROM1 prominin 1 1.27679
PTPN21 protein tyrosine phosphatase, non-receptor type 21 1.27644
TGFBR1 transforming growth factor, beta receptor 1 1.27639
RAB3B RAB3B, member RAS oncogene family 1.27623
SCARB2 scavenger receptor class B, member 2 1.27481
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.2675
TMEM63B transmembrane protein 63B 1.2647
LRRC8D leucine rich repeat containing 8 family, member D 1.2642

decreased expression

Symbol Name Standardized Value
PALLD palladin, cytoskeletal associated protein -4.76186
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -4.39471
CXORF57 chromosome X open reading frame 57 -4.05415
CDK8 cyclin-dependent kinase 8 -3.72105
EIF4A3 eukaryotic translation initiation factor 4A3 -3.45817
FAM122B family with sequence similarity 122B -3.25572
GOLM1 golgi membrane protein 1 -2.92243
ELP3 elongator acetyltransferase complex subunit 3 -2.89457
FXR2 fragile X mental retardation, autosomal homolog 2 -2.8535
SQLE squalene epoxidase -2.83931
HLA-C major histocompatibility complex, class I, C -2.81591
SMIM14 small integral membrane protein 14 -2.7783
MAOB monoamine oxidase B -2.76729
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.70524
CDK1 cyclin-dependent kinase 1 -2.6663
TMEM9B TMEM9 domain family, member B -2.66271
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.60995
ARMC4 armadillo repeat containing 4 -2.54096
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.51758
CLU clusterin -2.51304
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.5029
DCTN3 dynactin 3 (p22) -2.49809
MCMBP minichromosome maintenance complex binding protein -2.33804
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -2.3114
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.30156
XPO6 exportin 6 -2.29348
MCM6 minichromosome maintenance complex component 6 -2.28147
GOT1 glutamic-oxaloacetic transaminase 1, soluble -2.27024
PERP PERP, TP53 apoptosis effector -2.26605
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -2.25018
TECR trans-2,3-enoyl-CoA reductase -2.24638
STK39 serine threonine kinase 39 -2.23905
YBX1 Y box binding protein 1 -2.23407
HLA-DRA major histocompatibility complex, class II, DR alpha -2.20787
FKBP4 FK506 binding protein 4, 59kDa -2.20769
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -2.19258
HDAC1 histone deacetylase 1 -2.19114
STOM stomatin -2.18658
NQO1 NAD(P)H dehydrogenase, quinone 1 -2.17504
CSNK1A1 casein kinase 1, alpha 1 -2.16587
TXNRD1 thioredoxin reductase 1 -2.16453
AURKA aurora kinase A -2.15869
MT2A metallothionein 2A -2.13396
BAG4 BCL2-associated athanogene 4 -2.13308
CALM1 calmodulin 1 (phosphorylase kinase, delta) -2.12506
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.11929
CCDC47 coiled-coil domain containing 47 -2.10959
COPS3 COP9 signalosome subunit 3 -2.09283
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.07151
TES testin LIM domain protein -2.07142
CAV2 caveolin 2 -2.06811
FADS1 fatty acid desaturase 1 -2.05196
RAD51 RAD51 recombinase -2.04596
STIM2 stromal interaction molecule 2 -2.0451
PAM peptidylglycine alpha-amidating monooxygenase -2.03911
EIF4H eukaryotic translation initiation factor 4H -2.03
TFRC transferrin receptor -2.02529
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -2.01119
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.00094
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -1.99322
ZDHHC16 zinc finger, DHHC-type containing 16 -1.96732
MCM2 minichromosome maintenance complex component 2 -1.95951
MET MET proto-oncogene, receptor tyrosine kinase -1.95853
USP46 ubiquitin specific peptidase 46 -1.95789
DIXDC1 DIX domain containing 1 -1.95006
CCNF cyclin F -1.9347
ETV1 ets variant 1 -1.91846
DPP4 dipeptidyl-peptidase 4 -1.90398
CLCN4 chloride channel, voltage-sensitive 4 -1.90359
NRD1 nardilysin (N-arginine dibasic convertase) -1.90113
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -1.90113
TK1 thymidine kinase 1, soluble -1.89807
LRRC1 leucine rich repeat containing 1 -1.88623
KIF18B kinesin family member 18B -1.86618
DAZAP2 DAZ associated protein 2 -1.85673
CDC45 cell division cycle 45 -1.85055
FXR1 fragile X mental retardation, autosomal homolog 1 -1.84375
CD81 CD81 molecule -1.82746
CRABP2 cellular retinoic acid binding protein 2 -1.82686
RACGAP1 Rac GTPase activating protein 1 -1.82296
NUSAP1 nucleolar and spindle associated protein 1 -1.8216
EPS8 epidermal growth factor receptor pathway substrate 8 -1.81313
RPA1 replication protein A1, 70kDa -1.8119
AHCY adenosylhomocysteinase -1.79218
RFC5 replication factor C (activator 1) 5, 36.5kDa -1.77474
LIPH lipase, member H -1.75498
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -1.75172
ATAD2 ATPase family, AAA domain containing 2 -1.74516
PRDX3 peroxiredoxin 3 -1.7191
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) -1.71279
PDGFC platelet derived growth factor C -1.71111
EFR3A EFR3 homolog A (S. cerevisiae) -1.71006
PHGDH phosphoglycerate dehydrogenase -1.70754
CA11 carbonic anhydrase XI -1.70342
FUCA2 fucosidase, alpha-L- 2, plasma -1.70192
RHOBTB3 Rho-related BTB domain containing 3 -1.69578
CCAR2 cell cycle and apoptosis regulator 2 -1.69206
LUC7L2 LUC7-like 2 (S. cerevisiae) -1.69033
WDR76 WD repeat domain 76 -1.68272
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.67488
ORC2 origin recognition complex, subunit 2 -1.67153
SCPEP1 serine carboxypeptidase 1 -1.66553
MCM5 minichromosome maintenance complex component 5 -1.66543
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -1.66501
LZIC leucine zipper and CTNNBIP1 domain containing -1.66497
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.64929
HNRNPK heterogeneous nuclear ribonucleoprotein K -1.64464
ZNF350 zinc finger protein 350 -1.64125
RAB1B RAB1B, member RAS oncogene family -1.63834
SWAP70 SWAP switching B-cell complex 70kDa subunit -1.63755
MDH1 malate dehydrogenase 1, NAD (soluble) -1.63008
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -1.6209
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.62005
B2M beta-2-microglobulin -1.61478
GPI glucose-6-phosphate isomerase -1.61455
TGFB1 transforming growth factor, beta 1 -1.60928
TOP1 topoisomerase (DNA) I -1.59905
GAPDH glyceraldehyde-3-phosphate dehydrogenase -1.5939
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -1.58178
CTCF CCCTC-binding factor (zinc finger protein) -1.57699
REEP5 receptor accessory protein 5 -1.57675
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -1.57024
CCDC50 coiled-coil domain containing 50 -1.56879
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 -1.56755
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -1.56715
TFDP1 transcription factor Dp-1 -1.56683
MCM4 minichromosome maintenance complex component 4 -1.56197
UBE2K ubiquitin-conjugating enzyme E2K -1.55912
HPCAL1 hippocalcin-like 1 -1.55577
PRC1 protein regulator of cytokinesis 1 -1.55338
NASP nuclear autoantigenic sperm protein (histone-binding) -1.547
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -1.53935
PAGR1 PAXIP1 associated glutamate-rich protein 1 -1.53898
KCTD6 potassium channel tetramerization domain containing 6 -1.53761
DDAH2 dimethylarginine dimethylaminohydrolase 2 -1.53633
ALDOA aldolase A, fructose-bisphosphate -1.53399
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.53129
VRK1 vaccinia related kinase 1 -1.52638
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -1.5247
STK24 serine/threonine kinase 24 -1.52143
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -1.51797
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -1.51151
BIRC5 baculoviral IAP repeat containing 5 -1.50952
CKS1B CDC28 protein kinase regulatory subunit 1B -1.50543
OSBP2 oxysterol binding protein 2 -1.50473
UXS1 UDP-glucuronate decarboxylase 1 -1.50423
MCM3 minichromosome maintenance complex component 3 -1.50406
RRM1 ribonucleotide reductase M1 -1.50271
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -1.50003
GTSF1 gametocyte specific factor 1 -1.49915
BCL7B B-cell CLL/lymphoma 7B -1.49908
AATF apoptosis antagonizing transcription factor -1.49353
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -1.49207
PXK PX domain containing serine/threonine kinase -1.49094
TRIM28 tripartite motif containing 28 -1.48564
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -1.48538
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -1.48515
PARP2 poly (ADP-ribose) polymerase 2 -1.48373
TRIM56 tripartite motif containing 56 -1.4794
MT1E metallothionein 1E -1.47713
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.47408
EML2 echinoderm microtubule associated protein like 2 -1.47209
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -1.46853
KIF2C kinesin family member 2C -1.4653
NMU neuromedin U -1.46092
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -1.45989
KDSR 3-ketodihydrosphingosine reductase -1.45951
PPAT phosphoribosyl pyrophosphate amidotransferase -1.4576
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -1.45496
LPCAT3 lysophosphatidylcholine acyltransferase 3 -1.45404
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -1.44468
NUP188 nucleoporin 188kDa -1.4425
UGDH UDP-glucose 6-dehydrogenase -1.43704
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 -1.43675
TUG1 taurine up-regulated 1 (non-protein coding) -1.43562
GPSM2 G-protein signaling modulator 2 -1.43467
KRT19 keratin 19, type I -1.43255
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -1.43173
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.42961
PLIN3 perilipin 3 -1.42915
C9ORF41 chromosome 9 open reading frame 41 -1.42663
ACO1 aconitase 1, soluble -1.42553
METAP1 methionyl aminopeptidase 1 -1.42541
S100A14 S100 calcium binding protein A14 -1.42005
TBCD tubulin folding cofactor D -1.41866
ARNT aryl hydrocarbon receptor nuclear translocator -1.41554
AAMP angio-associated, migratory cell protein -1.41109
ADIPOR1 adiponectin receptor 1 -1.41056
VPS33B vacuolar protein sorting 33 homolog B (yeast) -1.39728
C12ORF75 chromosome 12 open reading frame 75 -1.39373
PTMS parathymosin -1.39143
SRSF1 serine/arginine-rich splicing factor 1 -1.38958
XAB2 XPA binding protein 2 -1.38383
ILF2 interleukin enhancer binding factor 2 -1.38084
LMNB2 lamin B2 -1.38021
C1QBP complement component 1, q subcomponent binding protein -1.37789
EIF3G eukaryotic translation initiation factor 3, subunit G -1.37671
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin -1.37577
CTR9 CTR9, Paf1/RNA polymerase II complex component -1.37504
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -1.37213
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -1.37202
NOLC1 nucleolar and coiled-body phosphoprotein 1 -1.37045
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -1.3618
GALNS galactosamine (N-acetyl)-6-sulfatase -1.36145
SPRYD7 SPRY domain containing 7 -1.35992
MT1L metallothionein 1L (gene/pseudogene) -1.35838
HFE hemochromatosis -1.35249
HJURP Holliday junction recognition protein -1.35112
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.35084
MTCH2 mitochondrial carrier 2 -1.34683
RIC1 RAB6A GEF complex partner 1 -1.3455
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -1.34546
INTS7 integrator complex subunit 7 -1.34087
USH2A Usher syndrome 2A (autosomal recessive, mild) -1.34037
HLA-B major histocompatibility complex, class I, B -1.33639
GBE1 glucan (1,4-alpha-), branching enzyme 1 -1.33568
CHRAC1 chromatin accessibility complex 1 -1.33482
EED embryonic ectoderm development -1.33314
MID1IP1 MID1 interacting protein 1 -1.33203
TUBGCP3 tubulin, gamma complex associated protein 3 -1.32985
ADGRE5 adhesion G protein-coupled receptor E5 -1.32827
PMPCB peptidase (mitochondrial processing) beta -1.32521
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.32402
PARP1 poly (ADP-ribose) polymerase 1 -1.32253
FAM83D family with sequence similarity 83, member D -1.32021
TOPBP1 topoisomerase (DNA) II binding protein 1 -1.31913
PRPF3 pre-mRNA processing factor 3 -1.31701
DHRS7B dehydrogenase/reductase (SDR family) member 7B -1.31596
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -1.3107
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 -1.30982
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.30876
ALG8 ALG8, alpha-1,3-glucosyltransferase -1.30736
NOL9 nucleolar protein 9 -1.30231
SCNN1A sodium channel, non voltage gated 1 alpha subunit -1.30018
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -1.30004
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -1.29925
PLK1 polo-like kinase 1 -1.29571
FH fumarate hydratase -1.29437
LDHA lactate dehydrogenase A -1.29171
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -1.28843
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -1.28775
ALAS1 5'-aminolevulinate synthase 1 -1.28745
TUBB4B tubulin, beta 4B class IVb -1.28684
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -1.28648
ALCAM activated leukocyte cell adhesion molecule -1.28479
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -1.28387
H1F0 H1 histone family, member 0 -1.28357
FBLN1 fibulin 1 -1.28192
ACAD9 acyl-CoA dehydrogenase family, member 9 -1.28054
GRB2 growth factor receptor-bound protein 2 -1.27885
KPNA4 karyopherin alpha 4 (importin alpha 3) -1.27578
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -1.27524
CFAP20 cilia and flagella associated protein 20 -1.27514
GTSE1 G-2 and S-phase expressed 1 -1.27483
BZW1 basic leucine zipper and W2 domains 1 -1.27445
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -1.27403
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -1.27196
NXF1 nuclear RNA export factor 1 -1.27193
OAT ornithine aminotransferase -1.27176
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -1.26995
MRPL48 mitochondrial ribosomal protein L48 -1.26573
TEX2 testis expressed 2 -1.26518
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -1.26035
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -1.25971
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -1.25954
HAT1 histone acetyltransferase 1 -1.25685
CFL2 cofilin 2 (muscle) -1.25633
FAM188B family with sequence similarity 188, member B -1.25418
FAM8A1 family with sequence similarity 8, member A1 -1.25392
HIATL1 hippocampus abundant transcript-like 1 -1.25221
NCAPD2 non-SMC condensin I complex, subunit D2 -1.2517
NELFCD negative elongation factor complex member C/D -1.25153
SUN2 Sad1 and UNC84 domain containing 2 -1.25118
DCAF6 DDB1 and CUL4 associated factor 6 -1.23852
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 -1.23743
SEC23B Sec23 homolog B (S. cerevisiae) -1.23677
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -1.23629
PPP6R3 protein phosphatase 6, regulatory subunit 3 -1.23586
SLC38A5 solute carrier family 38, member 5 -1.23574
MKX mohawk homeobox -1.23447
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -1.23405
SRSF2 serine/arginine-rich splicing factor 2 -1.23294
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -1.2319
CD47 CD47 molecule -1.23053
EWSR1 EWS RNA-binding protein 1 -1.22743
ALYREF Aly/REF export factor -1.22456
NUP50 nucleoporin 50kDa -1.22436
CPT1C carnitine palmitoyltransferase 1C -1.22214
SNCG synuclein, gamma (breast cancer-specific protein 1) -1.22206
GLG1 golgi glycoprotein 1 -1.21845
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -1.21629
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -1.21511
CD109 CD109 molecule -1.21376
HIPK3 homeodomain interacting protein kinase 3 -1.21246
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -1.21174
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -1.20754
DAZAP1 DAZ associated protein 1 -1.20439
AFF4 AF4/FMR2 family, member 4 -1.20067
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -1.20037
SEC24D SEC24 family member D -1.19558