CDK8_knockdown_88_GSE27869 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27869
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Genes

600 genes differentially expressed following the CDK8_knockdown_88_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
FAM160A2 family with sequence similarity 160, member A2 2.77371
INTS3 integrator complex subunit 3 2.68476
C14ORF119 chromosome 14 open reading frame 119 2.67952
TBCK TBC1 domain containing kinase 2.64172
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.60467
RWDD1 RWD domain containing 1 2.56158
UFSP2 UFM1-specific peptidase 2 2.53462
CSNK1E casein kinase 1, epsilon 2.46179
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 2.44609
EMC4 ER membrane protein complex subunit 4 2.43608
AZI2 5-azacytidine induced 2 2.42732
CDYL chromodomain protein, Y-like 2.42611
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.42413
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 2.37773
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 2.35194
NRSN2 neurensin 2 2.33495
UQCRH ubiquinol-cytochrome c reductase hinge protein 2.33473
VASP vasodilator-stimulated phosphoprotein 2.3259
CCDC71 coiled-coil domain containing 71 2.32541
TARBP1 TAR (HIV-1) RNA binding protein 1 2.32405
SCARF2 scavenger receptor class F, member 2 2.31265
POU2F1 POU class 2 homeobox 1 2.30963
EXOSC1 exosome component 1 2.30251
TMEM45B transmembrane protein 45B 2.30097
NBPF3 neuroblastoma breakpoint family, member 3 2.27232
ERMARD ER membrane-associated RNA degradation 2.255
ERRFI1 ERBB receptor feedback inhibitor 1 2.23728
EIF3B eukaryotic translation initiation factor 3, subunit B 2.23463
CRYGS crystallin, gamma S 2.23397
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.22767
RUFY2 RUN and FYVE domain containing 2 2.22694
SUMO1 small ubiquitin-like modifier 1 2.22578
NOP10 NOP10 ribonucleoprotein 2.21538
SDCCAG8 serologically defined colon cancer antigen 8 2.21421
STX6 syntaxin 6 2.20112
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.18285
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 2.18115
TAPT1 transmembrane anterior posterior transformation 1 2.18013
C22ORF31 chromosome 22 open reading frame 31 2.17911
FBXO31 F-box protein 31 2.17658
CABS1 calcium-binding protein, spermatid-specific 1 2.17414
IFITM2 interferon induced transmembrane protein 2 2.1579
KSR1 kinase suppressor of ras 1 2.15588
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.15304
LIN7C lin-7 homolog C (C. elegans) 2.14602
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 2.14434
SPAG7 sperm associated antigen 7 2.14213
EFCAB11 EF-hand calcium binding domain 11 2.1307
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.12965
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2.12919
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.12519
AQP10 aquaporin 10 2.11166
ANPEP alanyl (membrane) aminopeptidase 2.10839
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.10495
HSF2BP heat shock transcription factor 2 binding protein 2.10429
DPP8 dipeptidyl-peptidase 8 2.09144
DUSP12 dual specificity phosphatase 12 2.08359
NPC1L1 NPC1-like 1 2.08209
SAMM50 SAMM50 sorting and assembly machinery component 2.08097
KIAA1549 KIAA1549 2.07879
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 2.07145
IDI1 isopentenyl-diphosphate delta isomerase 1 2.07007
HDAC8 histone deacetylase 8 2.06861
UVRAG UV radiation resistance associated 2.06381
NPTXR neuronal pentraxin receptor 2.06123
MORC2 MORC family CW-type zinc finger 2 2.06066
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.05837
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.05661
EMC9 ER membrane protein complex subunit 9 2.0473
AQR aquarius intron-binding spliceosomal factor 2.0467
TIPRL TOR signaling pathway regulator 2.04538
THUMPD3-AS1 THUMPD3 antisense RNA 1 2.0448
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 2.04167
CUTA cutA divalent cation tolerance homolog (E. coli) 2.03547
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 2.03519
MFSD8 major facilitator superfamily domain containing 8 2.03327
TRAPPC4 trafficking protein particle complex 4 2.02742
KATNAL1 katanin p60 subunit A-like 1 2.02107
ERCC6L2 excision repair cross-complementation group 6-like 2 2.01763
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.01622
TPST2 tyrosylprotein sulfotransferase 2 2.01051
NNMT nicotinamide N-methyltransferase 2.00366
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 2.00115
C19ORF12 chromosome 19 open reading frame 12 1.99509
PRPF38B pre-mRNA processing factor 38B 1.99494
MBIP MAP3K12 binding inhibitory protein 1 1.99131
ANKRD49 ankyrin repeat domain 49 1.98729
RNASE3 ribonuclease, RNase A family, 3 1.98279
FBXW4 F-box and WD repeat domain containing 4 1.98199
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 1.98136
LARP1B La ribonucleoprotein domain family, member 1B 1.97795
FAM96A family with sequence similarity 96, member A 1.96765
NOTCH1 notch 1 1.96728
RPL38 ribosomal protein L38 1.96604
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 1.9574
DYNLT1 dynein, light chain, Tctex-type 1 1.95568
ZDHHC16 zinc finger, DHHC-type containing 16 1.9514
ZNF606 zinc finger protein 606 1.94918
UIMC1 ubiquitin interaction motif containing 1 1.94867
WNT10A wingless-type MMTV integration site family, member 10A 1.94499
CIB1 calcium and integrin binding 1 (calmyrin) 1.94154
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 1.93614
UBE2R2 ubiquitin-conjugating enzyme E2R 2 1.93105
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 1.9305
SH2D6 SH2 domain containing 6 1.92789
MITD1 MIT, microtubule interacting and transport, domain containing 1 1.92755
MRC2 mannose receptor, C type 2 1.92447
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.92183
ZFAND1 zinc finger, AN1-type domain 1 1.92025
TLK1 tousled-like kinase 1 1.91754
TRIM62 tripartite motif containing 62 1.91516
SRSF9 serine/arginine-rich splicing factor 9 1.91455
MRPS30 mitochondrial ribosomal protein S30 1.91014
PTGR2 prostaglandin reductase 2 1.9049
BRD1 bromodomain containing 1 1.90308
SV2A synaptic vesicle glycoprotein 2A 1.9018
CSN3 casein kappa 1.89811
METTL5 methyltransferase like 5 1.89692
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.88919
ZPR1 ZPR1 zinc finger 1.88704
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 1.88398
RPS27 ribosomal protein S27 1.88288
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 1.87461
DYNLRB1 dynein, light chain, roadblock-type 1 1.86959
SYT3 synaptotagmin III 1.86864
STIM1 stromal interaction molecule 1 1.86727
MOCS2 molybdenum cofactor synthesis 2 1.86502
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 1.86457
FLII flightless I homolog (Drosophila) 1.85712
C12ORF65 chromosome 12 open reading frame 65 1.85355
PHPT1 phosphohistidine phosphatase 1 1.85095
ESAM endothelial cell adhesion molecule 1.84427
GSTK1 glutathione S-transferase kappa 1 1.84251
MTMR9 myotubularin related protein 9 1.84031
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.83959
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 1.83918
FAN1 FANCD2/FANCI-associated nuclease 1 1.83849
NUDCD3 NudC domain containing 3 1.83742
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 1.83716
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 1.83643
DENND3 DENN/MADD domain containing 3 1.83596
PAPOLA poly(A) polymerase alpha 1.83528
AKTIP AKT interacting protein 1.83349
HCG18 HLA complex group 18 (non-protein coding) 1.83319
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.8273
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 1.82636
ERP29 endoplasmic reticulum protein 29 1.82618
FGFR1OP FGFR1 oncogene partner 1.82471
FBXO34 F-box protein 34 1.82463
ADD1 adducin 1 (alpha) 1.82189
CLEC11A C-type lectin domain family 11, member A 1.82022
ORC4 origin recognition complex, subunit 4 1.81806
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.81018
FBXL4 F-box and leucine-rich repeat protein 4 1.80988
VAX2 ventral anterior homeobox 2 1.80936
ARFRP1 ADP-ribosylation factor related protein 1 1.80704
BUD31 BUD31 homolog (S. cerevisiae) 1.80465
MLEC malectin 1.80142
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 1.79967
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 1.79138
RFC4 replication factor C (activator 1) 4, 37kDa 1.78843
C14ORF159 chromosome 14 open reading frame 159 1.78644
TMOD3 tropomodulin 3 (ubiquitous) 1.78572
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.78572
ACP2 acid phosphatase 2, lysosomal 1.78348
DNHD1 dynein heavy chain domain 1 1.78134
MTCH1 mitochondrial carrier 1 1.7808
FRMPD1 FERM and PDZ domain containing 1 1.7782
NKIRAS1 NFKB inhibitor interacting Ras-like 1 1.77149
CYB5R2 cytochrome b5 reductase 2 1.77106
TUBGCP4 tubulin, gamma complex associated protein 4 1.77077
MRRF mitochondrial ribosome recycling factor 1.76145
FLNC filamin C, gamma 1.75483
MAN2A2 mannosidase, alpha, class 2A, member 2 1.75457
TMEM50B transmembrane protein 50B 1.75287
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.75127
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.74838
CETN2 centrin, EF-hand protein, 2 1.74776
DCLRE1B DNA cross-link repair 1B 1.74721
RPS5 ribosomal protein S5 1.74355
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 1.7428
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 1.74199
TRAPPC2 trafficking protein particle complex 2 1.73918
TMED3 transmembrane emp24 protein transport domain containing 3 1.73735
SLC39A9 solute carrier family 39, member 9 1.73368
CABLES1 Cdk5 and Abl enzyme substrate 1 1.73268
PRPF6 pre-mRNA processing factor 6 1.73187
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 1.73151
IRF2BP1 interferon regulatory factor 2 binding protein 1 1.73058
LOC283788 FSHD region gene 1 pseudogene 1.73019
RHOBTB1 Rho-related BTB domain containing 1 1.7284
CDK5 cyclin-dependent kinase 5 1.72561
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1.7251
RFT1 RFT1 homolog (S. cerevisiae) 1.72349
SAP130 Sin3A-associated protein, 130kDa 1.72208
MAPK9 mitogen-activated protein kinase 9 1.72147
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 1.71585
PTRH2 peptidyl-tRNA hydrolase 2 1.71581
CAMLG calcium modulating ligand 1.71557
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.71545
TCF15 transcription factor 15 (basic helix-loop-helix) 1.71353
TMED1 transmembrane emp24 protein transport domain containing 1 1.70898
SLC39A13 solute carrier family 39 (zinc transporter), member 13 1.70849
C7ORF25 chromosome 7 open reading frame 25 1.70712
DHCR7 7-dehydrocholesterol reductase 1.70693
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 1.70669
GSTT1 glutathione S-transferase theta 1 1.70606
SCN1B sodium channel, voltage gated, type I beta subunit 1.70606
CLCC1 chloride channel CLIC-like 1 1.70543
MSRA methionine sulfoxide reductase A 1.70248
EXOC3 exocyst complex component 3 1.69829
EXT1 exostosin glycosyltransferase 1 1.69444
NPEPL1 aminopeptidase-like 1 1.69357
SDC4 syndecan 4 1.69354
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 1.69348
SNHG21 small nucleolar RNA host gene 21 1.6929
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 1.69277
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 1.69136
CYC1 cytochrome c-1 1.68965
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 1.68512
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 1.68387
GLCE glucuronic acid epimerase 1.67713
ARF3 ADP-ribosylation factor 3 1.67689
PRRC2B proline-rich coiled-coil 2B 1.67631
HEXA hexosaminidase A (alpha polypeptide) 1.67517
TMEM59L transmembrane protein 59-like 1.67243
THADA thyroid adenoma associated 1.67242
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 1.67147
PTPRB protein tyrosine phosphatase, receptor type, B 1.67105
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.6706
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 1.67041
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.66974
JMJD6 jumonji domain containing 6 1.66831
UNC5C unc-5 homolog C (C. elegans) 1.66687
SYT2 synaptotagmin II 1.66299
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) 1.6623
ALPK3 alpha-kinase 3 1.65981
TMEM185B transmembrane protein 185B 1.65823
RIOK1 RIO kinase 1 1.65669
SIK2 salt-inducible kinase 2 1.65516
EGLN1 egl-9 family hypoxia-inducible factor 1 1.65386
MTFR1 mitochondrial fission regulator 1 1.64942
CLIP3 CAP-GLY domain containing linker protein 3 1.64785
SPINK5 serine peptidase inhibitor, Kazal type 5 1.64696
C14ORF79 chromosome 14 open reading frame 79 1.64608
WRAP73 WD repeat containing, antisense to TP73 1.64438
MKRN1 makorin ring finger protein 1 1.64319
ZBTB20 zinc finger and BTB domain containing 20 1.64125
MAP3K12 mitogen-activated protein kinase kinase kinase 12 1.64097
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.64062
COX17 COX17 cytochrome c oxidase copper chaperone 1.63987
OR5V1 olfactory receptor, family 5, subfamily V, member 1 1.637
ANO10 anoctamin 10 1.63679
TXN2 thioredoxin 2 1.63504
VIMP VCP-interacting membrane selenoprotein 1.63483
TACC3 transforming, acidic coiled-coil containing protein 3 1.63308
IVD isovaleryl-CoA dehydrogenase 1.63134
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.63117
COBLL1 cordon-bleu WH2 repeat protein-like 1 1.62945
EIF5B eukaryotic translation initiation factor 5B 1.62591
EBF2 early B-cell factor 2 1.62004
XPO7 exportin 7 1.61947
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.6167
LSM10 LSM10, U7 small nuclear RNA associated 1.61594
TMEM260 transmembrane protein 260 1.6141
SRD5A3 steroid 5 alpha-reductase 3 1.61371
SERBP1 SERPINE1 mRNA binding protein 1 1.61298
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1.61078
KIAA0930 KIAA0930 1.61016
ZRANB3 zinc finger, RAN-binding domain containing 3 1.60966
CYTH4 cytohesin 4 1.60958
DHRS7 dehydrogenase/reductase (SDR family) member 7 1.60788
KLHL42 kelch-like family member 42 1.6078
GGCT gamma-glutamylcyclotransferase 1.60753
SMC6 structural maintenance of chromosomes 6 1.60744
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.60631
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.60594
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.60574
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.60566
MRS2 MRS2 magnesium transporter 1.60179
RBFA ribosome binding factor A (putative) 1.6014
LAMA3 laminin, alpha 3 1.60129
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) 1.59834
ZNF496 zinc finger protein 496 1.59594
FAM103A1 family with sequence similarity 103, member A1 1.59415
KIAA1467 KIAA1467 1.59407
THEM6 thioesterase superfamily member 6 1.59201
LTN1 listerin E3 ubiquitin protein ligase 1 1.59131
NUTF2 nuclear transport factor 2 1.59025
ATF4 activating transcription factor 4 1.59004
QDPR quinoid dihydropteridine reductase 1.58964
FBL fibrillarin 1.5894
ZNF747 zinc finger protein 747 1.58859
RPL26L1 ribosomal protein L26-like 1 1.58851
ABI2 abl-interactor 2 1.58552
SLC22A18 solute carrier family 22, member 18 1.5851
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.58497
PON2 paraoxonase 2 1.58404
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.58224
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 1.57994

decreased expression

Symbol Name Standardized Value
ALAS1 5'-aminolevulinate synthase 1 -3.31281
TTC5 tetratricopeptide repeat domain 5 -3.28838
KIAA0391 KIAA0391 -3.27288
CANX calnexin -3.16765
TERF2IP telomeric repeat binding factor 2, interacting protein -3.09212
OAZ2 ornithine decarboxylase antizyme 2 -3.06569
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -2.96988
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.95134
PCP4 Purkinje cell protein 4 -2.93227
UBE2F ubiquitin-conjugating enzyme E2F (putative) -2.88091
BAG4 BCL2-associated athanogene 4 -2.84589
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -2.84004
TADA2A transcriptional adaptor 2A -2.80748
RPLP2 ribosomal protein, large, P2 -2.80194
HSBP1 heat shock factor binding protein 1 -2.7285
RSBN1 round spermatid basic protein 1 -2.69207
PTPRD protein tyrosine phosphatase, receptor type, D -2.68099
PEX11A peroxisomal biogenesis factor 11 alpha -2.68074
ZNF567 zinc finger protein 567 -2.63005
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -2.61139
METRNL meteorin, glial cell differentiation regulator-like -2.60881
RBMXL1 RNA binding motif protein, X-linked-like 1 -2.60752
HSPA8 heat shock 70kDa protein 8 -2.55232
UBE2K ubiquitin-conjugating enzyme E2K -2.55149
IMPAD1 inositol monophosphatase domain containing 1 -2.5411
ZNF25 zinc finger protein 25 -2.53971
RMI1 RecQ mediated genome instability 1 -2.53148
HELZ helicase with zinc finger -2.44987
ZNF544 zinc finger protein 544 -2.44287
MEAF6 MYST/Esa1-associated factor 6 -2.43763
RPL21 ribosomal protein L21 -2.43001
ZNF3 zinc finger protein 3 -2.4211
TSFM Ts translation elongation factor, mitochondrial -2.41815
THAP4 THAP domain containing 4 -2.41694
LACTB lactamase, beta -2.41049
SRP19 signal recognition particle 19kDa -2.38128
CCDC6 coiled-coil domain containing 6 -2.36434
AMMECR1L AMMECR1-like -2.34989
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -2.34506
TLDC1 TBC/LysM-associated domain containing 1 -2.34202
PPP4R2 protein phosphatase 4, regulatory subunit 2 -2.31813
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.31576
MED4 mediator complex subunit 4 -2.31103
HMGB3 high mobility group box 3 -2.29751
KIN Kin17 DNA and RNA binding protein -2.27178
HP1BP3 heterochromatin protein 1, binding protein 3 -2.26497
WDR73 WD repeat domain 73 -2.25537
TUBGCP5 tubulin, gamma complex associated protein 5 -2.25459
ZNF268 zinc finger protein 268 -2.25312
MRFAP1 Morf4 family associated protein 1 -2.23831
RPS3 ribosomal protein S3 -2.23654
NUMB numb homolog (Drosophila) -2.22922
ZNF184 zinc finger protein 184 -2.22048
PHACTR4 phosphatase and actin regulator 4 -2.21131
PUS7 pseudouridylate synthase 7 (putative) -2.20973
ZNF583 zinc finger protein 583 -2.20148
RPL41 ribosomal protein L41 -2.19195
C11ORF58 chromosome 11 open reading frame 58 -2.18665
ITGB1BP1 integrin beta 1 binding protein 1 -2.18153
SH3D19 SH3 domain containing 19 -2.17353
RAP2A RAP2A, member of RAS oncogene family -2.16342
AAK1 AP2 associated kinase 1 -2.153
SCAND2P SCAN domain containing 2 pseudogene -2.14479
GRPR gastrin-releasing peptide receptor -2.13757
LINC01184 long intergenic non-protein coding RNA 1184 -2.13305
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -2.12601
PRKX protein kinase, X-linked -2.12465
DCTD dCMP deaminase -2.12459
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -2.11912
ZMAT2 zinc finger, matrin-type 2 -2.11038
PARL presenilin associated, rhomboid-like -2.10471
SETD6 SET domain containing 6 -2.10112
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -2.10017
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -2.09848
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 -2.09795
ETV5 ets variant 5 -2.09685
ATG14 autophagy related 14 -2.09511
C1ORF123 chromosome 1 open reading frame 123 -2.09276
TBKBP1 TBK1 binding protein 1 -2.09162
ZNF207 zinc finger protein 207 -2.09024
MRPL35 mitochondrial ribosomal protein L35 -2.08703
WDR82 WD repeat domain 82 -2.07111
PPHLN1 periphilin 1 -2.06581
FAM199X family with sequence similarity 199, X-linked -2.06314
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -2.05884
C1ORF216 chromosome 1 open reading frame 216 -2.05526
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -2.04502
HPS4 Hermansky-Pudlak syndrome 4 -2.04384
TSC1 tuberous sclerosis 1 -2.04192
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -2.0337
ZNF654 zinc finger protein 654 -2.02803
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -2.02779
ZNF140 zinc finger protein 140 -2.01842
MYNN myoneurin -2.01623
MRPS7 mitochondrial ribosomal protein S7 -2.00895
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.00475
OSBPL2 oxysterol binding protein-like 2 -2.00189
NDFIP1 Nedd4 family interacting protein 1 -2.00176
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -1.99993
LRRK1 leucine-rich repeat kinase 1 -1.99924
PRDX6 peroxiredoxin 6 -1.99873
TCEAL8 transcription elongation factor A (SII)-like 8 -1.99738
EGR1 early growth response 1 -1.99142
MRPS27 mitochondrial ribosomal protein S27 -1.99044
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -1.98642
KCTD13 potassium channel tetramerization domain containing 13 -1.98292
RAP1A RAP1A, member of RAS oncogene family -1.98282
ANKH ANKH inorganic pyrophosphate transport regulator -1.97284
EIF4B eukaryotic translation initiation factor 4B -1.97226
MTRF1L mitochondrial translational release factor 1-like -1.96992
GPR3 G protein-coupled receptor 3 -1.96946
KIAA1328 KIAA1328 -1.96642
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -1.96528
CREBL2 cAMP responsive element binding protein-like 2 -1.96126
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -1.9579
CLTA clathrin, light chain A -1.95384
GXYLT1 glucoside xylosyltransferase 1 -1.94569
BCAS2 breast carcinoma amplified sequence 2 -1.94426
ASCL3 achaete-scute family bHLH transcription factor 3 -1.94425
RNF166 ring finger protein 166 -1.94302
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -1.93634
GAS8 growth arrest-specific 8 -1.92949
RAB22A RAB22A, member RAS oncogene family -1.92802
GRAMD2 GRAM domain containing 2 -1.92162
TECPR2 tectonin beta-propeller repeat containing 2 -1.91888
ASB7 ankyrin repeat and SOCS box containing 7 -1.91696
ZNF565 zinc finger protein 565 -1.91536
WDR47 WD repeat domain 47 -1.89858
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 -1.89408
TMEM143 transmembrane protein 143 -1.89038
DUSP15 dual specificity phosphatase 15 -1.88785
TM4SF19 transmembrane 4 L six family member 19 -1.87808
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -1.87713
KIAA0141 KIAA0141 -1.87173
ZNF346 zinc finger protein 346 -1.87165
SERTAD2 SERTA domain containing 2 -1.87124
STRADB STE20-related kinase adaptor beta -1.87086
RBM22 RNA binding motif protein 22 -1.86811
ANKRD28 ankyrin repeat domain 28 -1.86399
DYNLL1 dynein, light chain, LC8-type 1 -1.86019
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -1.8584
ZNF616 zinc finger protein 616 -1.85654
BAG3 BCL2-associated athanogene 3 -1.85351
GDF9 growth differentiation factor 9 -1.85337
ZCCHC9 zinc finger, CCHC domain containing 9 -1.84923
DHRS4-AS1 DHRS4 antisense RNA 1 -1.84591
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) -1.843
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 -1.84268
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -1.83549
NFX1 nuclear transcription factor, X-box binding 1 -1.834
TMCO4 transmembrane and coiled-coil domains 4 -1.83168
MANBA mannosidase, beta A, lysosomal -1.83048
CASS4 Cas scaffolding protein family member 4 -1.82985
DHRSX dehydrogenase/reductase (SDR family) X-linked -1.82867
WASH1 WAS protein family homolog 1 -1.82767
DRAM1 DNA-damage regulated autophagy modulator 1 -1.82616
RPS16 ribosomal protein S16 -1.82474
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -1.82005
ZNF624 zinc finger protein 624 -1.8199
AGO2 argonaute RISC catalytic component 2 -1.81984
DUSP22 dual specificity phosphatase 22 -1.81741
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -1.81704
DESI1 desumoylating isopeptidase 1 -1.81557
DHRS3 dehydrogenase/reductase (SDR family) member 3 -1.81186
GSR glutathione reductase -1.80866
TBC1D10B TBC1 domain family, member 10B -1.80598
CKM creatine kinase, muscle -1.80433
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -1.79999
MRPS10 mitochondrial ribosomal protein S10 -1.79882
DCTN3 dynactin 3 (p22) -1.79696
DPP3 dipeptidyl-peptidase 3 -1.79535
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -1.79236
VEZT vezatin, adherens junctions transmembrane protein -1.79235
HRH1 histamine receptor H1 -1.79168
RBM19 RNA binding motif protein 19 -1.79
SAR1A secretion associated, Ras related GTPase 1A -1.78979
ANXA4 annexin A4 -1.78899
GADD45A growth arrest and DNA-damage-inducible, alpha -1.78751
COPZ1 coatomer protein complex, subunit zeta 1 -1.78021
CUL5 cullin 5 -1.77769
GDAP2 ganglioside induced differentiation associated protein 2 -1.7763
FAM216A family with sequence similarity 216, member A -1.77527
LCMT2 leucine carboxyl methyltransferase 2 -1.77275
UNC119 unc-119 homolog (C. elegans) -1.77242
NIT1 nitrilase 1 -1.77198
GIMAP4 GTPase, IMAP family member 4 -1.7715
KDM4A lysine (K)-specific demethylase 4A -1.76841
SLFN12 schlafen family member 12 -1.76792
FUZ fuzzy planar cell polarity protein -1.76781
ITFG3 integrin alpha FG-GAP repeat containing 3 -1.76665
SENP6 SUMO1/sentrin specific peptidase 6 -1.76461
CARKD carbohydrate kinase domain containing -1.76422
TBR1 T-box, brain, 1 -1.76323
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) -1.76286
DCAF10 DDB1 and CUL4 associated factor 10 -1.76262
C10ORF76 chromosome 10 open reading frame 76 -1.76105
PGAM1 phosphoglycerate mutase 1 (brain) -1.75453
ZDHHC17 zinc finger, DHHC-type containing 17 -1.75443
RBM4 RNA binding motif protein 4 -1.75113
ZNF12 zinc finger protein 12 -1.75041
PDCD6IP programmed cell death 6 interacting protein -1.74768
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.7469
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.74618
EED embryonic ectoderm development -1.74562
PTGR1 prostaglandin reductase 1 -1.74181
DRICH1 aspartate-rich 1 -1.74082
NCK1 NCK adaptor protein 1 -1.73727
CDK8 cyclin-dependent kinase 8 -1.73622
F2RL2 coagulation factor II (thrombin) receptor-like 2 -1.73516
TONSL tonsoku-like, DNA repair protein -1.73421
SGCE sarcoglycan, epsilon -1.73332
YIPF6 Yip1 domain family, member 6 -1.73295
LDLR low density lipoprotein receptor -1.73116
ADGRE5 adhesion G protein-coupled receptor E5 -1.73082
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -1.72662
TFAP2A-AS1 TFAP2A antisense RNA 1 -1.7266
DAP3 death associated protein 3 -1.72621
RNF2 ring finger protein 2 -1.726
SRPK2 SRSF protein kinase 2 -1.72466
FAM149B1 family with sequence similarity 149, member B1 -1.72124
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -1.72038
ZNF26 zinc finger protein 26 -1.71838
METAP1D methionyl aminopeptidase type 1D (mitochondrial) -1.71513
KRT36 keratin 36, type I -1.71445
KRTCAP2 keratinocyte associated protein 2 -1.71439
AEBP2 AE binding protein 2 -1.71422
RAB3A RAB3A, member RAS oncogene family -1.71411
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 -1.71062
CRY2 cryptochrome circadian clock 2 -1.70818
LMF1 lipase maturation factor 1 -1.7065
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -1.70645
MAP2K3 mitogen-activated protein kinase kinase 3 -1.70321
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -1.70255
MRPL40 mitochondrial ribosomal protein L40 -1.7016
GCSH glycine cleavage system protein H (aminomethyl carrier) -1.70043
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 -1.69752
ZNF330 zinc finger protein 330 -1.69551
STXBP1 syntaxin binding protein 1 -1.69546
ADARB1 adenosine deaminase, RNA-specific, B1 -1.69497
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 -1.6934
SSBP3 single stranded DNA binding protein 3 -1.69157
HOXA11 homeobox A11 -1.68563
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.68378
LOC153811 uncharacterized LOC153811 -1.68141
OSER1 oxidative stress responsive serine-rich 1 -1.67852
GPSM1 G-protein signaling modulator 1 -1.67787
SETD1B SET domain containing 1B -1.67723
ZCCHC17 zinc finger, CCHC domain containing 17 -1.67409
NUP54 nucleoporin 54kDa -1.67165
ZSCAN30 zinc finger and SCAN domain containing 30 -1.67134
ABHD14B abhydrolase domain containing 14B -1.66955
CLK2 CDC-like kinase 2 -1.66863
FAM118B family with sequence similarity 118, member B -1.66847
HSPB8 heat shock 22kDa protein 8 -1.6683
AMOT angiomotin -1.667
HEXIM1 hexamethylene bis-acetamide inducible 1 -1.66647
PAPOLG poly(A) polymerase gamma -1.66606
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.66339
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -1.66329
NFS1 NFS1 cysteine desulfurase -1.66161
CLEC2B C-type lectin domain family 2, member B -1.66132
CHMP3 charged multivesicular body protein 3 -1.66077
RAB5C RAB5C, member RAS oncogene family -1.66054
TMEM261 transmembrane protein 261 -1.6604
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -1.65999
ZDHHC4 zinc finger, DHHC-type containing 4 -1.65847
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -1.6554
VBP1 von Hippel-Lindau binding protein 1 -1.65537
PTPRA protein tyrosine phosphatase, receptor type, A -1.65495
OXCT1 3-oxoacid CoA transferase 1 -1.65131
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.64963
NFAM1 NFAT activating protein with ITAM motif 1 -1.64907
WDR12 WD repeat domain 12 -1.6487
MTCH2 mitochondrial carrier 2 -1.64636
FN3KRP fructosamine 3 kinase related protein -1.64537
FAM192A family with sequence similarity 192, member A -1.64461
CISD1 CDGSH iron sulfur domain 1 -1.64372
SLC26A11 solute carrier family 26 (anion exchanger), member 11 -1.64287
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.6414
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.63883
LMO2 LIM domain only 2 (rhombotin-like 1) -1.63804
SLC25A38 solute carrier family 25, member 38 -1.6362
LHFPL4 lipoma HMGIC fusion partner-like 4 -1.63555
AHSP alpha hemoglobin stabilizing protein -1.63499
DAD1 defender against cell death 1 -1.63489
C12ORF45 chromosome 12 open reading frame 45 -1.63484
AADAT aminoadipate aminotransferase -1.63398
UBAP2L ubiquitin associated protein 2-like -1.63088
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -1.6294
CD302 CD302 molecule -1.6292
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 -1.62541
FIP1L1 factor interacting with PAPOLA and CPSF1 -1.62514
TXNL1 thioredoxin-like 1 -1.62419
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 -1.62309
ZNF738 zinc finger protein 738 -1.62249
METTL17 methyltransferase like 17 -1.62171
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -1.62141
TSKS testis-specific serine kinase substrate -1.62112
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -1.62041
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -1.61992