CDK9 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description cyclin-dependent kinase 9|The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1025)
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Genes

100 substrates of the kinase CDK9 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
DCP1A decapping mRNA 1A
EPS8L2 EPS8-like 2
CHAMP1 chromosome alignment maintaining phosphoprotein 1
GPR162 G protein-coupled receptor 162
USP20 ubiquitin specific peptidase 20
SARAF store-operated calcium entry-associated regulatory factor
BBC3 BCL2 binding component 3
CRTC1 CREB regulated transcription coactivator 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF2 serine/arginine-rich splicing factor 2
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
WTIP Wilms tumor 1 interacting protein
PKP4 plakophilin 4
CASP7 caspase 7, apoptosis-related cysteine peptidase
WRNIP1 Werner helicase interacting protein 1
TRA2A transformer 2 alpha homolog (Drosophila)
LBR lamin B receptor
KMT2B lysine (K)-specific methyltransferase 2B
PML promyelocytic leukemia
SLBP stem-loop binding protein
C19ORF26 chromosome 19 open reading frame 26
THRAP3 thyroid hormone receptor associated protein 3
IQCC IQ motif containing C
ATXN2 ataxin 2
U2AF2 U2 small nuclear RNA auxiliary factor 2
NKX2-4 NK2 homeobox 4
FOXK2 forkhead box K2
FOXK1 forkhead box K1
ZNF687 zinc finger protein 687
LSM11 LSM11, U7 small nuclear RNA associated
KAT6B K(lysine) acetyltransferase 6B
SPATA2L spermatogenesis associated 2-like
CCDC137 coiled-coil domain containing 137
RBL2 retinoblastoma-like 2
SP110 SP110 nuclear body protein
SAPCD2 suppressor APC domain containing 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PRR14 proline rich 14
NHSL1 NHS-like 1
APC2 adenomatosis polyposis coli 2
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
INO80C INO80 complex subunit C
ZSWIM8 zinc finger, SWIM-type containing 8
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
SH3PXD2B SH3 and PX domains 2B
SNIP1 Smad nuclear interacting protein 1
ZNF638 zinc finger protein 638
MEX3D mex-3 RNA binding family member D
RABEPK Rab9 effector protein with kelch motifs
MDC1 mediator of DNA-damage checkpoint 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PROSER3 proline and serine rich 3
SLAIN2 SLAIN motif family, member 2
ATAD2 ATPase family, AAA domain containing 2
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
MPLKIP M-phase specific PLK1 interacting protein
UHRF1 ubiquitin-like with PHD and ring finger domains 1
ULK1 unc-51 like autophagy activating kinase 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
RBMXL1 RNA binding motif protein, X-linked-like 1
CXORF23 chromosome X open reading frame 23
C2CD4C C2 calcium-dependent domain containing 4C
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
GAS2L1 growth arrest-specific 2 like 1
TBKBP1 TBK1 binding protein 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
NCOA2 nuclear receptor coactivator 2
NCOA5 nuclear receptor coactivator 5
RIF1 replication timing regulatory factor 1
HOXA4 homeobox A4
WNK3 WNK lysine deficient protein kinase 3
FOXM1 forkhead box M1
APC adenomatous polyposis coli
ANKLE2 ankyrin repeat and LEM domain containing 2
KIF1C kinesin family member 1C
RANBP10 RAN binding protein 10
TPR translocated promoter region, nuclear basket protein
DGKQ diacylglycerol kinase, theta 110kDa
MTCL1 microtubule crosslinking factor 1
TMC8 transmembrane channel-like 8
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
SPEN spen family transcriptional repressor
SPEG SPEG complex locus
MISP mitotic spindle positioning
KCTD2 potassium channel tetramerization domain containing 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
TMPRSS13 transmembrane protease, serine 13
SRRM1 serine/arginine repetitive matrix 1
SRRM2 serine/arginine repetitive matrix 2
RAI1 retinoic acid induced 1
CCDC8 coiled-coil domain containing 8
NSD1 nuclear receptor binding SET domain protein 1
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
FOXO1 forkhead box O1
KANK3 KN motif and ankyrin repeat domains 3
TMIGD2 transmembrane and immunoglobulin domain containing 2
TLCD2 TLC domain containing 2
DCP1B decapping mRNA 1B