| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin-dependent kinase 9|The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1025) |
| External Link | https://ncbi.nlm.nih.gov/gene/1025 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CDK9 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0165542 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.0145753 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0114587 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0107329 |
| TNS3 | tensin 3 | 0.00974559 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00961746 |
| CCNG1 | cyclin G1 | 0.00960397 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0095985 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00950223 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00950037 |
| C21ORF33 | chromosome 21 open reading frame 33 | 0.009439 |
| METTL7A | methyltransferase like 7A | 0.00939519 |
| RTN2 | reticulon 2 | 0.00910036 |
| PODXL | podocalyxin-like | 0.00903671 |
| OPHN1 | oligophrenin 1 | 0.00892937 |
| KRT19 | keratin 19, type I | 0.00890773 |
| SIRT3 | sirtuin 3 | 0.00889564 |
| ANXA6 | annexin A6 | 0.00884114 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00868523 |
| TP53 | tumor protein p53 | 0.00861212 |
| TRIB2 | tribbles pseudokinase 2 | 0.00853096 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00839926 |
| NEBL | nebulette | 0.00828334 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00826532 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00815727 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00809289 |
| HEATR1 | HEAT repeat containing 1 | 0.00808562 |
| CIRBP | cold inducible RNA binding protein | 0.00807043 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00805909 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00805576 |
| CLDN10 | claudin 10 | 0.00796084 |
| MLEC | malectin | 0.00792872 |
| TCTA | T-cell leukemia translocation altered | 0.00790957 |
| SDC1 | syndecan 1 | 0.00788157 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00785581 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00783366 |
| GNAS | GNAS complex locus | 0.00782196 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00779712 |
| CCNB1 | cyclin B1 | 0.00775274 |
| COLEC12 | collectin sub-family member 12 | 0.00760082 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00759459 |
| RAB25 | RAB25, member RAS oncogene family | 0.00757094 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 0.00749876 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00747892 |
| CNTN1 | contactin 1 | 0.00739156 |
| EPCAM | epithelial cell adhesion molecule | 0.00735394 |
| CYB561 | cytochrome b561 | 0.00732397 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0072851 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00726412 |
| PLAT | plasminogen activator, tissue | 0.00724718 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00721314 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00720638 |
| ANOS1 | anosmin 1 | 0.00720572 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | 0.00720385 |
| VCL | vinculin | 0.00711352 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00708108 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00704659 |
| MMP12 | matrix metallopeptidase 12 | 0.00703175 |
| PFKL | phosphofructokinase, liver | 0.00697928 |
| PEG10 | paternally expressed 10 | 0.0069724 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00694446 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0069423 |
| COG7 | component of oligomeric golgi complex 7 | 0.00693509 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00689927 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00689349 |
| OLFML2A | olfactomedin-like 2A | 0.0068714 |
| THBS1 | thrombospondin 1 | 0.00686772 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00686286 |
| XYLT1 | xylosyltransferase I | 0.00683991 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00682488 |
| ACKR3 | atypical chemokine receptor 3 | 0.0068147 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.0068087 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00680288 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00679335 |
| F12 | coagulation factor XII (Hageman factor) | 0.00678848 |
| GAS2L1 | growth arrest-specific 2 like 1 | 0.0067772 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00676836 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00674314 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00672577 |
| CPNE1 | copine I | 0.00671832 |
| THBS2 | thrombospondin 2 | 0.00671143 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.00669468 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00662385 |
| TCTN2 | tectonic family member 2 | 0.00658805 |
| CD93 | CD93 molecule | 0.00654942 |
| LTA4H | leukotriene A4 hydrolase | 0.00654841 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00653916 |
| TAPBP | TAP binding protein (tapasin) | 0.00653782 |
| SORD | sorbitol dehydrogenase | 0.00649049 |
| ZW10 | zw10 kinetochore protein | 0.0064809 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00636963 |
| RBM8A | RNA binding motif protein 8A | 0.00635585 |
| ADD3 | adducin 3 (gamma) | 0.00635126 |
| COL5A1 | collagen, type V, alpha 1 | 0.00634759 |
| MTA1 | metastasis associated 1 | 0.00631204 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.0063083 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00628556 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00625998 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00625116 |
| CHKB | choline kinase beta | 0.00622439 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0061711 |
| LDB2 | LIM domain binding 2 | 0.00617026 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00616981 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00615355 |
| SCG5 | secretogranin V | 0.00615008 |
| SLC35E2B | solute carrier family 35, member E2B | 0.00611541 |
| MB | myoglobin | 0.00610601 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.00607654 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00604658 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00603155 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00600729 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00600669 |
| SLC2A4RG | SLC2A4 regulator | 0.00598368 |
| ABLIM1 | actin binding LIM protein 1 | 0.00597572 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00597132 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00592055 |
| HTRA1 | HtrA serine peptidase 1 | 0.00590703 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00590459 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00589306 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00589212 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.00589139 |
| JAG2 | jagged 2 | 0.00588684 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 0.00587373 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00586666 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 0.0058652 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00584835 |
| AHCY | adenosylhomocysteinase | 0.00584265 |
| FCGBP | Fc fragment of IgG binding protein | 0.00583671 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00582039 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00581417 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00581041 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00578993 |
| TMEM176B | transmembrane protein 176B | 0.00578986 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0057857 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00578242 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00577951 |
| FBLN5 | fibulin 5 | 0.00577425 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00575141 |
| NBEAL2 | neurobeachin-like 2 | 0.00574992 |
| TYRP1 | tyrosinase-related protein 1 | 0.00574768 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.00574647 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00573534 |
| PALLD | palladin, cytoskeletal associated protein | 0.00572945 |
| DUSP3 | dual specificity phosphatase 3 | 0.00570098 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.00569035 |
| SEPTIN2 | septin 2 | 0.00568884 |
| RXRA | retinoid X receptor, alpha | 0.00568702 |
| TPP1 | tripeptidyl peptidase I | 0.0056831 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00567594 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00567582 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00566928 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 0.00566431 |
| RNASET2 | ribonuclease T2 | 0.00565509 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00564723 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00564427 |
| OBSL1 | obscurin-like 1 | 0.0056391 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0055947 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00557952 |
| PEG3 | paternally expressed 3 | 0.00557397 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.00556742 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00556693 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.00553986 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | 0.0055386 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.0055377 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00551419 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00550967 |
| FERMT1 | fermitin family member 1 | 0.00549014 |
| AHNAK | AHNAK nucleoprotein | 0.00548578 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00548378 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00545813 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00544574 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00544361 |
| IL17RB | interleukin 17 receptor B | 0.00544275 |
| COQ9 | coenzyme Q9 | 0.00544113 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0054385 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00543634 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00543626 |
| APEH | acylaminoacyl-peptide hydrolase | 0.00543567 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00540752 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00540266 |
| CTBP1 | C-terminal binding protein 1 | 0.00538995 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00538681 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00538576 |
| RGS10 | regulator of G-protein signaling 10 | 0.00538193 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.00537973 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00536883 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 0.00536668 |
| CAPNS1 | calpain, small subunit 1 | 0.00536298 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00536234 |
| FMO1 | flavin containing monooxygenase 1 | 0.00535145 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.00534503 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00533569 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00532755 |
| SNX17 | sorting nexin 17 | 0.00532322 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0053204 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00531935 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00530892 |
| EP400 | E1A binding protein p400 | 0.00530525 |
| NID2 | nidogen 2 (osteonidogen) | 0.00530135 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0053002 |
| CBR4 | carbonyl reductase 4 | 0.00529891 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00529868 |
| OLFM1 | olfactomedin 1 | 0.00529475 |
| A2M | alpha-2-macroglobulin | 0.00527669 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00527573 |
| MUC16 | mucin 16, cell surface associated | 0.00526398 |
| ERLIN2 | ER lipid raft associated 2 | 0.00526348 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00525866 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00525546 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0052536 |
| RAB22A | RAB22A, member RAS oncogene family | 0.00524829 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00523916 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00523199 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | 0.00522427 |
| FLNA | filamin A, alpha | 0.00521434 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00521366 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00519867 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.00519295 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00518987 |
| GPC1 | glypican 1 | 0.00518767 |
| MXRA5 | matrix-remodelling associated 5 | 0.00518559 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00518407 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00518176 |
| COG4 | component of oligomeric golgi complex 4 | 0.00517639 |
| PFKP | phosphofructokinase, platelet | 0.0051735 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00517325 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00517122 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00516087 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0051559 |
| NUDCD3 | NudC domain containing 3 | 0.00515151 |
| PGBD5 | piggyBac transposable element derived 5 | 0.00515098 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00513683 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00513473 |
| MMP11 | matrix metallopeptidase 11 | 0.00511925 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00511493 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00511111 |
| ADCY7 | adenylate cyclase 7 | 0.00511015 |
| VEGFA | vascular endothelial growth factor A | 0.00510899 |
| FABP7 | fatty acid binding protein 7, brain | 0.00510773 |
| GSTZ1 | glutathione S-transferase zeta 1 | 0.00510565 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00509342 |
| COPS6 | COP9 signalosome subunit 6 | 0.00508195 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) | 0.00507384 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.00507356 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00505928 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00505596 |
| NONO | non-POU domain containing, octamer-binding | 0.00505308 |
| SYT17 | synaptotagmin XVII | 0.0050432 |
| MIS18A | MIS18 kinetochore protein A | 0.00503966 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00502953 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0161061 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0123085 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.012198 |
| MT1M | metallothionein 1M | -0.0120666 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0117601 |
| LTF | lactotransferrin | -0.0114634 |
| APOD | apolipoprotein D | -0.0111214 |
| S100A12 | S100 calcium binding protein A12 | -0.0104865 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0104124 |
| ELANE | elastase, neutrophil expressed | -0.0100818 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00983781 |
| S100A9 | S100 calcium binding protein A9 | -0.00977693 |
| NEFH | neurofilament, heavy polypeptide | -0.00948267 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00929612 |
| BRD4 | bromodomain containing 4 | -0.0092826 |
| EGR1 | early growth response 1 | -0.00913047 |
| CPM | carboxypeptidase M | -0.00905605 |
| HMOX1 | heme oxygenase 1 | -0.00888696 |
| CTH | cystathionine gamma-lyase | -0.00888281 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00877544 |
| DUSP5 | dual specificity phosphatase 5 | -0.00865532 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -0.00856523 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00848013 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00841826 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00837007 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0083241 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00831803 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00829061 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00828974 |
| PLBD1 | phospholipase B domain containing 1 | -0.00820925 |
| CSTA | cystatin A (stefin A) | -0.00819215 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00818679 |
| ATF3 | activating transcription factor 3 | -0.00818453 |
| FPGS | folylpolyglutamate synthase | -0.00805117 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00804347 |
| HBD | hemoglobin, delta | -0.0080411 |
| CLC | Charcot-Leyden crystal galectin | -0.00784397 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00781839 |
| MIR22HG | MIR22 host gene | -0.00775056 |
| S100A8 | S100 calcium binding protein A8 | -0.00771359 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00752391 |
| HOXB6 | homeobox B6 | -0.00750663 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00750474 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00747879 |
| HOXB2 | homeobox B2 | -0.00745759 |
| GLRX | glutaredoxin (thioltransferase) | -0.0074543 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00745316 |
| ELOVL4 | ELOVL fatty acid elongase 4 | -0.0074519 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00742764 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.00738595 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00729072 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00728937 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00722109 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00720459 |
| MGAM | maltase-glucoamylase | -0.0071665 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00714431 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -0.00710609 |
| NOP56 | NOP56 ribonucleoprotein | -0.00707471 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -0.00703984 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00700515 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00697448 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00692669 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00692542 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0069203 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00688003 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00685727 |
| SEC61G | Sec61 gamma subunit | -0.00684376 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00682606 |
| RIT1 | Ras-like without CAAX 1 | -0.00681387 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00681181 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00680313 |
| CLGN | calmegin | -0.00679916 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00677934 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00675659 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00673076 |
| HOXB7 | homeobox B7 | -0.00672739 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.00671459 |
| MMP8 | matrix metallopeptidase 8 | -0.00669335 |
| ANXA1 | annexin A1 | -0.00666278 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.00666147 |
| MT1X | metallothionein 1X | -0.00656215 |
| PERP | PERP, TP53 apoptosis effector | -0.00648146 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.00647397 |
| DSTN | destrin (actin depolymerizing factor) | -0.00646383 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00644981 |
| CRYM | crystallin, mu | -0.00640932 |
| APMAP | adipocyte plasma membrane associated protein | -0.00640294 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00639302 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00638477 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0063811 |
| ARG2 | arginase 2 | -0.00637293 |
| YAP1 | Yes-associated protein 1 | -0.0063727 |
| CLDN1 | claudin 1 | -0.00635799 |
| INSL3 | insulin-like 3 (Leydig cell) | -0.00635516 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00634567 |
| HOXC6 | homeobox C6 | -0.0063326 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00630781 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00630033 |
| LY96 | lymphocyte antigen 96 | -0.00629303 |
| RAB32 | RAB32, member RAS oncogene family | -0.00629062 |
| CTSG | cathepsin G | -0.00628336 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00628167 |
| TRIB3 | tribbles pseudokinase 3 | -0.00627349 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00623629 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00622715 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.00621685 |
| CCN3 | cellular communication network factor 3 | -0.00619476 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00611579 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00609255 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00608751 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -0.00608356 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00606494 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00605125 |
| JMJD6 | jumonji domain containing 6 | -0.00605105 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00604556 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.0060449 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00603482 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00602514 |
| ZNF432 | zinc finger protein 432 | -0.00601559 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00598716 |
| NUCB2 | nucleobindin 2 | -0.00596537 |
| GOLM1 | golgi membrane protein 1 | -0.00595816 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00595037 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | -0.00594551 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00594388 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.00593905 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00593159 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00592929 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00592604 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -0.00589695 |
| CHMP4A | charged multivesicular body protein 4A | -0.00589454 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00587846 |
| ANXA3 | annexin A3 | -0.00587833 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00587825 |
| GSPT2 | G1 to S phase transition 2 | -0.00587292 |
| TMEM87A | transmembrane protein 87A | -0.00585214 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.00583532 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00582337 |
| NINL | ninein-like | -0.00582309 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -0.00581368 |
| PLIN1 | perilipin 1 | -0.00581111 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00580592 |
| TASP1 | taspase, threonine aspartase, 1 | -0.00580559 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00577731 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00576486 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00574306 |
| ZNF430 | zinc finger protein 430 | -0.00573805 |
| NUP58 | nucleoporin 58 | -0.00572176 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00571864 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.00571449 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00571257 |
| WTAP | Wilms tumor 1 associated protein | -0.00571251 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00569595 |
| MPO | myeloperoxidase | -0.00569228 |
| BTG2 | BTG family, member 2 | -0.00564751 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | -0.0056425 |
| CRYAB | crystallin, alpha B | -0.005616 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00560767 |
| CSNK2A1 | casein kinase 2, alpha 1 polypeptide | -0.00560555 |
| PROCR | protein C receptor, endothelial | -0.00559742 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00558895 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.00557538 |
| CLU | clusterin | -0.00556746 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00555739 |
| KLHL7 | kelch-like family member 7 | -0.00555106 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00554524 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00554077 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00552805 |
| ING3 | inhibitor of growth family, member 3 | -0.00551543 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00551541 |
| XIC | X chromosome inactivation center | -0.00551352 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.00550249 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.00549904 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00549659 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00549416 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -0.00548986 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0054806 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0054624 |
| BRD2 | bromodomain containing 2 | -0.00542067 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00541611 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00540781 |
| MAGEA4 | melanoma antigen family A4 | -0.00540638 |
| CCND2 | cyclin D2 | -0.00540181 |
| ZNF586 | zinc finger protein 586 | -0.00539015 |
| PRPF18 | pre-mRNA processing factor 18 | -0.00537842 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00537602 |
| CST3 | cystatin C | -0.00537557 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00537478 |
| ZNF12 | zinc finger protein 12 | -0.00536291 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00535132 |
| TENM1 | teneurin transmembrane protein 1 | -0.00535015 |
| PLA1A | phospholipase A1 member A | -0.0053431 |
| UBB | ubiquitin B | -0.00534253 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00534242 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00533886 |
| CA2 | carbonic anhydrase II | -0.00533293 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00531415 |
| MYO6 | myosin VI | -0.00531239 |
| SNX13 | sorting nexin 13 | -0.00530707 |
| TXN | thioredoxin | -0.00529319 |
| PON3 | paraoxonase 3 | -0.00529167 |
| MTF2 | metal response element binding transcription factor 2 | -0.00528997 |
| ANAPC10 | anaphase promoting complex subunit 10 | -0.00527715 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0052664 |
| MED21 | mediator complex subunit 21 | -0.00526155 |
| JUNB | jun B proto-oncogene | -0.00524629 |
| KIN | Kin17 DNA and RNA binding protein | -0.00523251 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00523148 |
| ZNF43 | zinc finger protein 43 | -0.00522577 |
| RNFT1 | ring finger protein, transmembrane 1 | -0.00521985 |
| ZNF91 | zinc finger protein 91 | -0.00521945 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00520762 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00520557 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00520058 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00519096 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00518881 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00518608 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.00517982 |
| ZNF394 | zinc finger protein 394 | -0.00516991 |
| TOB2 | transducer of ERBB2, 2 | -0.00516347 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00515872 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00514388 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00514319 |
| TSPAN6 | tetraspanin 6 | -0.00513282 |
| MT1G | metallothionein 1G | -0.00512109 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00510597 |
| CFD | complement factor D (adipsin) | -0.00510093 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -0.00509348 |
| DDRGK1 | DDRGK domain containing 1 | -0.00508938 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | -0.00508834 |
| ODC1 | ornithine decarboxylase 1 | -0.00508043 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00507889 |
| BPI | bactericidal/permeability-increasing protein | -0.00507488 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | -0.00507378 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.00506968 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | -0.00506806 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00506328 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00505749 |
| TIPIN | TIMELESS interacting protein | -0.00505557 |
| PMF1 | polyamine-modulated factor 1 | -0.00504899 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | -0.00504192 |
| NNMT | nicotinamide N-methyltransferase | -0.00504084 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00501419 |
| BCHE | butyrylcholinesterase | -0.00501215 |
| ZNF117 | zinc finger protein 117 | -0.005011 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -0.00501087 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -0.00499532 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00499066 |
| CRP | C-reactive protein, pentraxin-related | -0.00499041 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00498618 |
