CDK9 Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description cyclin-dependent kinase 9|The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1025)
External Link http://www.ncbi.nlm.nih.gov/gene/1025
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Genes

3 interacting proteins for CDK9 from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
LARP7 La ribonucleoprotein domain family, member 7 0.382386
HEXIM1 hexamethylene bis-acetamide inducible 1 0.357413
CCNT1 cyclin T1 0.085092