| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | cyclin-dependent kinase inhibitor 1A (p21, Cip1)|This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010] (NCBI Entrez Gene Database, 1026) |
| External Link | https://ncbi.nlm.nih.gov/gene/1026 |
| Similar Terms | |
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499 genes differentially expressed following the CDKN1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0155353 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0138034 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0129537 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0128883 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0123594 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.012031 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0117784 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0117272 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.0115312 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0113968 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0112474 |
| RHOB | ras homolog family member B | 0.0110364 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0109757 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.0105428 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0104496 |
| MEIS2 | Meis homeobox 2 | 0.0101258 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0101 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00976411 |
| S100P | S100 calcium binding protein P | 0.00954236 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00939286 |
| ANXA3 | annexin A3 | 0.0091725 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00916982 |
| NXN | nucleoredoxin | 0.00916459 |
| AMOTL2 | angiomotin like 2 | 0.00911449 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.00906864 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00899595 |
| RTN2 | reticulon 2 | 0.00895207 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00884891 |
| RND3 | Rho family GTPase 3 | 0.00873786 |
| RIN2 | Ras and Rab interactor 2 | 0.00872023 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00871484 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00859813 |
| MGAM | maltase-glucoamylase | 0.00859806 |
| SIK1 | salt-inducible kinase 1 | 0.00858239 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00855544 |
| TYMP | thymidine phosphorylase | 0.00836905 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00825755 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00824957 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00823929 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00818041 |
| TYMS | thymidylate synthetase | 0.0081633 |
| EFNB2 | ephrin-B2 | 0.00814865 |
| KIF5B | kinesin family member 5B | 0.00814745 |
| DNM1 | dynamin 1 | 0.00812568 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00808425 |
| TGFB1 | transforming growth factor, beta 1 | 0.00805716 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.0080505 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00800671 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00798074 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00796128 |
| PMP22 | peripheral myelin protein 22 | 0.00793023 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00787137 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00782572 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00782431 |
| PKM | pyruvate kinase, muscle | 0.00776908 |
| LTF | lactotransferrin | 0.00775479 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00772033 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00770895 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00768282 |
| TLN1 | talin 1 | 0.00765668 |
| RRM2 | ribonucleotide reductase M2 | 0.0076023 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00758723 |
| DGKZ | diacylglycerol kinase, zeta | 0.00758119 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.0075745 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00755842 |
| WDR7 | WD repeat domain 7 | 0.00755087 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00754983 |
| PAX5 | paired box 5 | 0.00754731 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00754553 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00750039 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0074969 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00749461 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00745529 |
| CTBP2 | C-terminal binding protein 2 | 0.00742355 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00739137 |
| S100A9 | S100 calcium binding protein A9 | 0.00738097 |
| TRIM28 | tripartite motif containing 28 | 0.00737042 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00735159 |
| BRD4 | bromodomain containing 4 | 0.00726988 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00726318 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00724944 |
| JAG1 | jagged 1 | 0.00723779 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.00722416 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00720321 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00719412 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00717563 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00716086 |
| PLK2 | polo-like kinase 2 | 0.00715301 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00713756 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00713643 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00706911 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00705442 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00705151 |
| H2AX | H2A.X variant histone | 0.00705146 |
| KRT7 | keratin 7, type II | 0.00704962 |
| TRIB3 | tribbles pseudokinase 3 | 0.00703747 |
| CCNL2 | cyclin L2 | 0.0070336 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00702207 |
| CUX1 | cut-like homeobox 1 | 0.00698136 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00695621 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00695131 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00694933 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00693131 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00690184 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00690111 |
| RBPMS | RNA binding protein with multiple splicing | 0.00689423 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | 0.00688114 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.00683947 |
| SBF1 | SET binding factor 1 | 0.00679865 |
| MID1IP1 | MID1 interacting protein 1 | 0.00676443 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00667061 |
| NUCB1 | nucleobindin 1 | 0.00666595 |
| TGFA | transforming growth factor, alpha | 0.00662681 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0066134 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 0.00651438 |
| ACTN4 | actinin, alpha 4 | 0.00647773 |
| AUTS2 | autism susceptibility candidate 2 | 0.00647758 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00647269 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00647089 |
| JUNB | jun B proto-oncogene | 0.00646732 |
| S100A12 | S100 calcium binding protein A12 | 0.00645258 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.00645069 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00645017 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00643459 |
| ODC1 | ornithine decarboxylase 1 | 0.0064148 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00641308 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 0.00639255 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00638576 |
| TGM2 | transglutaminase 2 | 0.00636704 |
| TSPAN12 | tetraspanin 12 | 0.00636064 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00635191 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00633158 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.0063234 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00630044 |
| MEST | mesoderm specific transcript | 0.00629145 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00628614 |
| PTK2 | protein tyrosine kinase 2 | 0.00625626 |
| APMAP | adipocyte plasma membrane associated protein | 0.00625525 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.0062548 |
| CCDC86 | coiled-coil domain containing 86 | 0.00624683 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00621012 |
| ACO2 | aconitase 2, mitochondrial | 0.00619675 |
| CST7 | cystatin F (leukocystatin) | 0.00618631 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00618461 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.00617732 |
| BPI | bactericidal/permeability-increasing protein | 0.00616538 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00616349 |
| CDC34 | cell division cycle 34 | 0.0061585 |
| CLC | Charcot-Leyden crystal galectin | 0.00615621 |
| RPL10 | ribosomal protein L10 | 0.00615187 |
| ABHD17A | abhydrolase domain containing 17A | 0.00615119 |
| RNF19B | ring finger protein 19B | 0.00614466 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00613567 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.00613465 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.00611722 |
| NMU | neuromedin U | 0.0061044 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.006102 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00609699 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00608293 |
| KIAA0930 | KIAA0930 | 0.0060822 |
| WASF1 | WAS protein family, member 1 | 0.00607168 |
| YBX3 | Y box binding protein 3 | 0.00606052 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 0.00604944 |
| CAMP | cathelicidin antimicrobial peptide | 0.00601831 |
| DMPK | dystrophia myotonica-protein kinase | 0.00600197 |
| PPL | periplakin | 0.00600022 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | 0.00598787 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0059479 |
| PLD3 | phospholipase D family, member 3 | 0.00594582 |
| CERK | ceramide kinase | 0.0059396 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00593727 |
| USP48 | ubiquitin specific peptidase 48 | 0.0059172 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00587714 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00587678 |
| DENND4B | DENN/MADD domain containing 4B | 0.00587279 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.005858 |
| SMAD7 | SMAD family member 7 | 0.00584706 |
| DUSP1 | dual specificity phosphatase 1 | 0.0058449 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00584351 |
| STK39 | serine threonine kinase 39 | 0.00583641 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00580697 |
| HHEX | hematopoietically expressed homeobox | 0.00579318 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00577715 |
| NUP50 | nucleoporin 50kDa | 0.00577308 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00577162 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00575627 |
| TXLNA | taxilin alpha | 0.00573257 |
| CAV2 | caveolin 2 | 0.00571954 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.00570256 |
| MMP9 | matrix metallopeptidase 9 | 0.00569729 |
| CLDN4 | claudin 4 | 0.00566311 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00565909 |
| RC3H2 | ring finger and CCCH-type domains 2 | 0.00565401 |
| MED15 | mediator complex subunit 15 | 0.00565069 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00563939 |
| PLXNB2 | plexin B2 | 0.005634 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00563295 |
| CCNA2 | cyclin A2 | 0.00562665 |
| PTK2B | protein tyrosine kinase 2 beta | 0.0056256 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0056156 |
| DMXL2 | Dmx-like 2 | 0.00560033 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00559825 |
| FBLN1 | fibulin 1 | 0.00558642 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.00558497 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00557155 |
| IFT122 | intraflagellar transport 122 | 0.00556378 |
| FOXF1 | forkhead box F1 | 0.00554535 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00554321 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.0055367 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | 0.00552691 |
| LYST | lysosomal trafficking regulator | 0.00551641 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00551465 |
| CDA | cytidine deaminase | 0.00550963 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00550735 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00550696 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.00549733 |
| DAZAP1 | DAZ associated protein 1 | 0.00548883 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | 0.00546935 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00546886 |
| FOXM1 | forkhead box M1 | 0.00546385 |
| FGL2 | fibrinogen-like 2 | 0.00544556 |
| TIMELESS | timeless circadian clock | 0.00542268 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00542193 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00541724 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00540794 |
| S100A8 | S100 calcium binding protein A8 | 0.00539728 |
| PDE10A | phosphodiesterase 10A | 0.00539702 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00538635 |
| DVL1 | dishevelled segment polarity protein 1 | 0.00537703 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.00536933 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00536924 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00536816 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00535862 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00535726 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00535269 |
| NELFB | negative elongation factor complex member B | 0.00535187 |
| DGCR8 | DGCR8 microprocessor complex subunit | 0.00535185 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.00535143 |
| CENPM | centromere protein M | 0.00534939 |
| CD9 | CD9 molecule | 0.00534104 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00533029 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00532903 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00531604 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | 0.00531515 |
| NAV2 | neuron navigator 2 | 0.0053151 |
| CLGN | calmegin | 0.00531219 |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) | 0.00531172 |
| PLPP3 | phospholipid phosphatase 3 | 0.00531125 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00530818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT1X | metallothionein 1X | -0.0128772 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0117161 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0116315 |
| AK4 | adenylate kinase 4 | -0.0114778 |
| MATN2 | matrilin 2 | -0.0111083 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0110859 |
| S100B | S100 calcium binding protein B | -0.0107553 |
| MT1H | metallothionein 1H | -0.0106544 |
| THBS2 | thrombospondin 2 | -0.0106148 |
| PLP1 | proteolipid protein 1 | -0.0103206 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0102996 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0100787 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0100509 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00994677 |
| VCAN | versican | -0.00986484 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00980333 |
| SELL | selectin L | -0.00967922 |
| MAL | mal, T-cell differentiation protein | -0.00959492 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00954526 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00947411 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00946239 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00940224 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00932702 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00930365 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00930176 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00925662 |
| NSG1 | neuron specific gene family member 1 | -0.0091522 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00907638 |
| OXTR | oxytocin receptor | -0.00906721 |
| MT1G | metallothionein 1G | -0.00906604 |
| PMP2 | peripheral myelin protein 2 | -0.00904088 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00900966 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00900506 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00897136 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00880006 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00875367 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0086762 |
| FABP7 | fatty acid binding protein 7, brain | -0.00866694 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00866044 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00865817 |
| TYRP1 | tyrosinase-related protein 1 | -0.00848876 |
| ATP10B | ATPase, class V, type 10B | -0.0084632 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00844351 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00843024 |
| DOK5 | docking protein 5 | -0.00835867 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00832183 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00829768 |
| MT1F | metallothionein 1F | -0.00825611 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00822778 |
| GAP43 | growth associated protein 43 | -0.00819219 |
| RBM34 | RNA binding motif protein 34 | -0.00818738 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00815471 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00810368 |
| POSTN | periostin, osteoblast specific factor | -0.00802566 |
| FABP1 | fatty acid binding protein 1, liver | -0.00797241 |
| OLFML3 | olfactomedin-like 3 | -0.0079182 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00790936 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00788743 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00783723 |
| PLIN3 | perilipin 3 | -0.0077708 |
| LAGE3 | L antigen family, member 3 | -0.00775202 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00774153 |
| AZIN1 | antizyme inhibitor 1 | -0.00773467 |
| S100A10 | S100 calcium binding protein A10 | -0.00768176 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00765353 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00764651 |
| MEN1 | multiple endocrine neoplasia I | -0.0075635 |
| GFUS | GDP-L-fucose synthase | -0.00749272 |
| MT2A | metallothionein 2A | -0.00745185 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00741503 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00740657 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00739494 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.00736508 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00736369 |
| FANCA | Fanconi anemia, complementation group A | -0.00732922 |
| JAM2 | junctional adhesion molecule 2 | -0.00731464 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00729972 |
| TMEM255A | transmembrane protein 255A | -0.00729386 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00723066 |
| PNMA8A | PNMA family member 8A | -0.00719495 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00716262 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.0071514 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00711834 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00711563 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.0070963 |
| GPM6B | glycoprotein M6B | -0.00708637 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00706009 |
| XPO7 | exportin 7 | -0.00705197 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.00704558 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00698863 |
| KIAA0226L | KIAA0226-like | -0.00698471 |
| VSNL1 | visinin-like 1 | -0.00697308 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00692756 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00691686 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00691677 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00690887 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00690501 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00688555 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00685527 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -0.00684316 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00682998 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00681446 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00678673 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.006761 |
| DMD | dystrophin | -0.00671581 |
| GPM6A | glycoprotein M6A | -0.00670639 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00670628 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00668143 |
| RGS10 | regulator of G-protein signaling 10 | -0.00664992 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00660903 |
| SP110 | SP110 nuclear body protein | -0.00658917 |
| NUTF2 | nuclear transport factor 2 | -0.00655992 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00655141 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00654963 |
| TSPAN31 | tetraspanin 31 | -0.0065401 |
| COPZ2 | coatomer protein complex, subunit zeta 2 | -0.00653962 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.00652089 |
| MFAP5 | microfibrillar associated protein 5 | -0.00651212 |
| APOD | apolipoprotein D | -0.00646385 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00646171 |
| S100A7 | S100 calcium binding protein A7 | -0.00645423 |
| CD99 | CD99 molecule | -0.00644745 |
| METTL7A | methyltransferase like 7A | -0.00644744 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00644284 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00642902 |
| ITM2A | integral membrane protein 2A | -0.00639175 |
| PRKCA | protein kinase C, alpha | -0.00638905 |
| RNASET2 | ribonuclease T2 | -0.00638217 |
| ANO10 | anoctamin 10 | -0.00637866 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00636736 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00633839 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00632902 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00632372 |
| SSPN | sarcospan | -0.0063124 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00630251 |
| GLOD4 | glyoxalase domain containing 4 | -0.00629209 |
| TCTN2 | tectonic family member 2 | -0.00627801 |
| CCDC90B | coiled-coil domain containing 90B | -0.00626346 |
| CCNG1 | cyclin G1 | -0.00622276 |
| RPL36 | ribosomal protein L36 | -0.0062088 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00619122 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -0.00617228 |
| EGR2 | early growth response 2 | -0.00616815 |
| MT1E | metallothionein 1E | -0.00615731 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00615456 |
| BEX1 | brain expressed, X-linked 1 | -0.00612476 |
| NGRN | neugrin, neurite outgrowth associated | -0.00612103 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00611417 |
| CHRDL1 | chordin-like 1 | -0.0060829 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00608099 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00607467 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00607364 |
| GDF3 | growth differentiation factor 3 | -0.0060695 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -0.00606868 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00606481 |
| ESD | esterase D | -0.00603775 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | -0.00603143 |
| ATP10A | ATPase, class V, type 10A | -0.00602936 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00599524 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00598596 |
| KRT1 | keratin 1, type II | -0.00598115 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00597516 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00597356 |
| GPX2 | glutathione peroxidase 2 | -0.00597053 |
| DAXX | death-domain associated protein | -0.00596734 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00596343 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00595248 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.00595205 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | -0.00594935 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00594127 |
| PLK1 | polo-like kinase 1 | -0.00593331 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00592255 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00592219 |
| AREG | amphiregulin | -0.00590915 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00590003 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0058876 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00588201 |
| RAB8B | RAB8B, member RAS oncogene family | -0.00587187 |
| TRIM22 | tripartite motif containing 22 | -0.00585931 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00585741 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00585125 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00584617 |
| ADD3 | adducin 3 (gamma) | -0.00583712 |
| PLLP | plasmolipin | -0.00583399 |
| GAS2 | growth arrest-specific 2 | -0.0058201 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00580559 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | -0.00579769 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00577619 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00577107 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00576295 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.00576264 |
| TSPAN3 | tetraspanin 3 | -0.00575371 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00574442 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.0057269 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00572358 |
| GMFB | glia maturation factor, beta | -0.00571335 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -0.00571013 |
| COX5B | cytochrome c oxidase subunit Vb | -0.00570214 |
| ASS1 | argininosuccinate synthase 1 | -0.00567058 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00565603 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -0.00565358 |
| SMAD2 | SMAD family member 2 | -0.00564041 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.00562964 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.0056203 |
| OLFM1 | olfactomedin 1 | -0.00561352 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.0056052 |
| HOMER1 | homer scaffolding protein 1 | -0.00559305 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00559024 |
| COQ8A | coenzyme Q8A | -0.00558603 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00558096 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00557938 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00555652 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00554897 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.00554103 |
| EPHB2 | EPH receptor B2 | -0.00552608 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.0055245 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00551833 |
| RPL36AL | ribosomal protein L36a-like | -0.00551692 |
| SLC35E3 | solute carrier family 35, member E3 | -0.00551135 |
| FNTA | farnesyltransferase, CAAX box, alpha | -0.00551127 |
| MIA | melanoma inhibitory activity | -0.00549227 |
| EAPP | E2F-associated phosphoprotein | -0.0054754 |
| APOA2 | apolipoprotein A-II | -0.00547537 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00547527 |
| XIC | X chromosome inactivation center | -0.00546945 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00545365 |
| PHF20 | PHD finger protein 20 | -0.0054476 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -0.00542717 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00542686 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00541615 |
| PITX3 | paired-like homeodomain 3 | -0.00540507 |
| LY86 | lymphocyte antigen 86 | -0.00540303 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00538338 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0053819 |
| OPHN1 | oligophrenin 1 | -0.00536024 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.00533742 |
| SPAG16 | sperm associated antigen 16 | -0.00532781 |
| DUOX2 | dual oxidase 2 | -0.00532666 |
| CHMP1B | charged multivesicular body protein 1B | -0.00532359 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00531591 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00530717 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -0.00530055 |
| GPX7 | glutathione peroxidase 7 | -0.00530007 |
| MAP1A | microtubule-associated protein 1A | -0.00529365 |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) | -0.00529161 |
| MAGT1 | magnesium transporter 1 | -0.00529054 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00529037 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00528767 |
| CHEK2 | checkpoint kinase 2 | -0.00528148 |
| CFI | complement factor I | -0.0052786 |
