CDX2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description caudal type homeobox 2|This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 1045)
External Link https://ncbi.nlm.nih.gov/gene/1045
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Genes

498 genes differentially expressed following the CDX2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
VEGFA vascular endothelial growth factor A 0.0149168
TRIB2 tribbles pseudokinase 2 0.0134507
IDO1 indoleamine 2,3-dioxygenase 1 0.0112186
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.0112132
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0110527
COPS7A COP9 signalosome subunit 7A 0.0106585
PEG10 paternally expressed 10 0.0106477
RRAGA Ras-related GTP binding A 0.0104831
WT1 Wilms tumor 1 0.0104501
ENO2 enolase 2 (gamma, neuronal) 0.0103739
CD9 CD9 molecule 0.0102651
LPAR6 lysophosphatidic acid receptor 6 0.0102173
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00987373
LEF1 lymphoid enhancer-binding factor 1 0.00981504
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00975835
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00959708
GCLC glutamate-cysteine ligase, catalytic subunit 0.009489
PDGFC platelet derived growth factor C 0.0093895
ACP3 acid phosphatase 3 0.00922664
GPR88 G protein-coupled receptor 88 0.0092055
COL9A2 collagen, type IX, alpha 2 0.00916746
CXCL13 chemokine (C-X-C motif) ligand 13 0.0091645
XCL1 chemokine (C motif) ligand 1 0.0089945
IL2RB interleukin 2 receptor, beta 0.00898095
CXCL10 chemokine (C-X-C motif) ligand 10 0.00897564
CADM1 cell adhesion molecule 1 0.00879323
SPEN spen family transcriptional repressor 0.00877375
PTK2B protein tyrosine kinase 2 beta 0.00864692
CXCL11 chemokine (C-X-C motif) ligand 11 0.00858447
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0085515
BASP1 brain abundant, membrane attached signal protein 1 0.00844498
PIR pirin (iron-binding nuclear protein) 0.00842828
EFNB2 ephrin-B2 0.00837807
LGALS2 lectin, galactoside-binding, soluble, 2 0.00816869
RORA RAR-related orphan receptor A 0.00814149
KLK2 kallikrein-related peptidase 2 0.00802792
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00789916
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00782405
ALOX5 arachidonate 5-lipoxygenase 0.00781253
MPPED2 metallophosphoesterase domain containing 2 0.0078031
BCHE butyrylcholinesterase 0.00772984
CLEC10A C-type lectin domain family 10, member A 0.0077221
MTMR2 myotubularin related protein 2 0.00771842
RNPS1 RNA binding protein S1, serine-rich domain 0.00764935
IGFBP1 insulin-like growth factor binding protein 1 0.00763744
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00763114
TGFBI transforming growth factor, beta-induced, 68kDa 0.00762256
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.00760269
SIDT2 SID1 transmembrane family, member 2 0.00757567
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00755493
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0075483
RNF167 ring finger protein 167 0.00753416
IGSF6 immunoglobulin superfamily, member 6 0.00752018
RAB6A RAB6A, member RAS oncogene family 0.0074208
KLK3 kallikrein-related peptidase 3 0.00739879
NPC2 Niemann-Pick disease, type C2 0.00738246
CCL5 chemokine (C-C motif) ligand 5 0.00737396
VCAM1 vascular cell adhesion molecule 1 0.00735445
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.00735188
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00734982
SMAD7 SMAD family member 7 0.00734841
CLGN calmegin 0.00732438
MEIS2 Meis homeobox 2 0.00731911
TRIM13 tripartite motif containing 13 0.0073152
IL10RA interleukin 10 receptor, alpha 0.00730067
EPHA4 EPH receptor A4 0.00728199
PAEP progestagen-associated endometrial protein 0.00726098
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00725602
SUN1 Sad1 and UNC84 domain containing 1 0.00722315
RAB20 RAB20, member RAS oncogene family 0.00719277
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00715406
GPR65 G protein-coupled receptor 65 0.00713629
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00713252
IPO13 importin 13 0.0070388
CTNND1 catenin (cadherin-associated protein), delta 1 0.00703554
EPS8 epidermal growth factor receptor pathway substrate 8 0.00699592
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00698389
MLF2 myeloid leukemia factor 2 0.00695223
PPT1 palmitoyl-protein thioesterase 1 0.00690601
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00685941
CUX2 cut-like homeobox 2 0.006845
GLUD1 glutamate dehydrogenase 1 0.00680672
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00680473
ELOVL5 ELOVL fatty acid elongase 5 0.00679631
CREB1 cAMP responsive element binding protein 1 0.00677342
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00675403
KIF5B kinesin family member 5B 0.00672752
YME1L1 YME1-like 1 ATPase 0.00672544
IFI44 interferon-induced protein 44 0.00670942
NOTCH2 notch 2 0.00668973
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.00666697
TASP1 taspase, threonine aspartase, 1 0.00664342
CD86 CD86 molecule 0.00660431
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00660217
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00659504
GPR183 G protein-coupled receptor 183 0.00652066
PDLIM4 PDZ and LIM domain 4 0.00651944
JAG1 jagged 1 0.00648535
GSAP gamma-secretase activating protein 0.00647895
PHACTR1 phosphatase and actin regulator 1 0.00646797
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.00646786
MAPK1 mitogen-activated protein kinase 1 0.00644275
ZNF266 zinc finger protein 266 0.0064267
HIC2 hypermethylated in cancer 2 0.0063915
CXCL9 chemokine (C-X-C motif) ligand 9 0.00634861
ARG2 arginase 2 0.00634624
DAPK1 death-associated protein kinase 1 0.0063428
RXRA retinoid X receptor, alpha 0.00632434
CCL20 chemokine (C-C motif) ligand 20 0.00629044
DPP4 dipeptidyl-peptidase 4 0.00628427
ACSL3 acyl-CoA synthetase long-chain family member 3 0.00628393
FGL2 fibrinogen-like 2 0.00627188
CHKB choline kinase beta 0.00623977
DENND2B DENN domain containing 2B 0.00623264
PICALM phosphatidylinositol binding clathrin assembly protein 0.00622506
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.0062129
GZMK granzyme K (granzyme 3; tryptase II) 0.00618786
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.00617993
TFAM transcription factor A, mitochondrial 0.00617191
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00615631
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 0.0061351
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00612538
CRYBG1 crystallin beta-gamma domain containing 1 0.00610777
IFNG interferon, gamma 0.0061056
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00609624
TUG1 taurine up-regulated 1 (non-protein coding) 0.00609511
KYNU kynureninase 0.00608624
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.00608607
PCP4 Purkinje cell protein 4 0.00606182
TLK2 tousled-like kinase 2 0.00605814
PFKP phosphofructokinase, platelet 0.00605455
TTC3 tetratricopeptide repeat domain 3 0.0060533
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00603978
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.00603795
TKTL1 transketolase-like 1 0.00603426
CCN3 cellular communication network factor 3 0.00603004
SNX10 sorting nexin 10 0.00602138
PRKCA protein kinase C, alpha 0.00601909
CCR2 chemokine (C-C motif) receptor 2 0.00601709
GIMAP6 GTPase, IMAP family member 6 0.00597156
HMGN4 high mobility group nucleosomal binding domain 4 0.00596658
TPSAB1 tryptase alpha/beta 1 0.00596544
AGRN agrin 0.00596429
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00595347
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.00594515
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00594253
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00594189
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00592496
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00590256
CTH cystathionine gamma-lyase 0.00589523
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00588909
CRYL1 crystallin, lambda 1 0.00588506
PSPH phosphoserine phosphatase 0.0058722
DNM1L dynamin 1-like 0.00587079
SCO2 SCO2 cytochrome c oxidase assembly protein 0.00586701
CDC20 cell division cycle 20 0.00586272
NPTN neuroplastin 0.00586053
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0058446
BTN3A1 butyrophilin, subfamily 3, member A1 0.00584316
SOAT1 sterol O-acyltransferase 1 0.00584187
MYO5A myosin VA (heavy chain 12, myoxin) 0.0058357
EBAG9 estrogen receptor binding site associated, antigen, 9 0.00583064
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.00582615
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.00582254
PFN2 profilin 2 0.0058203
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.00582018
GNLY granulysin 0.00581843
NUMA1 nuclear mitotic apparatus protein 1 0.00579528
GTPBP1 GTP binding protein 1 0.00578242
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00577623
GPR18 G protein-coupled receptor 18 0.0057637
FOLH1B folate hydrolase 1B 0.00574933
ZMYM2 zinc finger, MYM-type 2 0.00574777
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00574056
ZBTB10 zinc finger and BTB domain containing 10 0.00573587
PAK1IP1 PAK1 interacting protein 1 0.00573009
SEC23A Sec23 homolog A (S. cerevisiae) 0.00572965
PSME4 proteasome (prosome, macropain) activator subunit 4 0.00572677
BTN3A3 butyrophilin, subfamily 3, member A3 0.00572223
TMEM184B transmembrane protein 184B 0.00572155
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.00571298
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00571086
OPN3 opsin 3 0.00570919
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00568695
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00568629
DCT dopachrome tautomerase 0.00568613
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00568357
ATXN10 ataxin 10 0.00567987
GRSF1 G-rich RNA sequence binding factor 1 0.00566847
WDR41 WD repeat domain 41 0.00566552
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00565971
M6PR mannose-6-phosphate receptor (cation dependent) 0.00564865
ANXA4 annexin A4 0.00564707
CLEC7A C-type lectin domain family 7, member A 0.00564182
CCDC88A coiled-coil domain containing 88A 0.00563706
TFEC transcription factor EC 0.00562726
TARP TCR gamma alternate reading frame protein 0.00561584
METAP1 methionyl aminopeptidase 1 0.00559179
RIT1 Ras-like without CAAX 1 0.00558798
PBLD phenazine biosynthesis-like protein domain containing 0.00558559
PXN paxillin 0.00557925
RPS5 ribosomal protein S5 0.00557856
STK38L serine/threonine kinase 38 like 0.00557066
TPI1 triosephosphate isomerase 1 0.00556078
PKM pyruvate kinase, muscle 0.00555749
IFI44L interferon-induced protein 44-like 0.0055566
SSX1 synovial sarcoma, X breakpoint 1 0.00553264
NCKAP1 NCK-associated protein 1 0.00552922
GLIPR1 GLI pathogenesis-related 1 0.00552422
ZDHHC4 zinc finger, DHHC-type containing 4 0.00551884
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 0.00551744
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00550801
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00549838
IL18RAP interleukin 18 receptor accessory protein 0.00548877
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.00548336
IL7 interleukin 7 0.00547936
INSL3 insulin-like 3 (Leydig cell) 0.00547758
CD46 CD46 molecule, complement regulatory protein 0.00547295
TBL1X transducin (beta)-like 1X-linked 0.00547023
NISCH nischarin 0.00546402
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.00546166
MPRIP myosin phosphatase Rho interacting protein 0.00544906
CNN3 calponin 3, acidic 0.0054489
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00544632
PMEPA1 prostate transmembrane protein, androgen induced 1 0.00544601
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.00543602
PRF1 perforin 1 (pore forming protein) 0.00541586
USP48 ubiquitin specific peptidase 48 0.00540307
NEK3 NIMA-related kinase 3 0.00538602
WNT5B wingless-type MMTV integration site family, member 5B 0.00537964
CREBL2 cAMP responsive element binding protein-like 2 0.00537794
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 0.00537751
BCAS3 breast carcinoma amplified sequence 3 0.00537361
TMEM14A transmembrane protein 14A 0.00537156
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.00535602
ANKMY2 ankyrin repeat and MYND domain containing 2 0.0053507
CTBS chitobiase, di-N-acetyl- 0.00534548
RGS1 regulator of G-protein signaling 1 0.00534299
RAD17 RAD17 homolog (S. pombe) 0.00533998
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.00532931
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00532793
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.00531674
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.00531379
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00531143
APOC1 apolipoprotein C-I 0.00529902
GNMT glycine N-methyltransferase 0.00529862
CCNA1 cyclin A1 0.00529073
CD7 CD7 molecule 0.00528244

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0187058
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0186863
CLU clusterin -0.0184544
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0175597
CXCL12 chemokine (C-X-C motif) ligand 12 -0.016493
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0159108
S100A7 S100 calcium binding protein A7 -0.0148476
S100P S100 calcium binding protein P -0.0147515
HBB hemoglobin, beta -0.0143825
TFF1 trefoil factor 1 -0.013691
CA2 carbonic anhydrase II -0.0133763
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0131536
FABP4 fatty acid binding protein 4, adipocyte -0.01311
CRYAB crystallin, alpha B -0.013068
HSPB8 heat shock 22kDa protein 8 -0.0127479
STXBP2 syntaxin binding protein 2 -0.0125405
GAS1 growth arrest-specific 1 -0.0124229
DCN decorin -0.0122782
ABLIM1 actin binding LIM protein 1 -0.0120804
SFRP1 secreted frizzled-related protein 1 -0.0120718
MMP3 matrix metallopeptidase 3 -0.0117949
CLTB clathrin, light chain B -0.011605
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0115102
MGLL monoglyceride lipase -0.0113685
MFAP5 microfibrillar associated protein 5 -0.0111246
FHL1 four and a half LIM domains 1 -0.0111048
MAB21L2 mab-21-like 2 (C. elegans) -0.0110083
NEBL nebulette -0.0109131
RELN reelin -0.0108673
SPRR1A small proline-rich protein 1A -0.0107698
LAMA2 laminin, alpha 2 -0.0105241
SYT1 synaptotagmin I -0.010492
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0103907
FBLN5 fibulin 5 -0.0102891
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0101644
AKAP8 A kinase (PRKA) anchor protein 8 -0.0101221
SCGB2A2 secretoglobin, family 2A, member 2 -0.0100676
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0100462
TFF3 trefoil factor 3 (intestinal) -0.00999025
CHGB chromogranin B -0.00992584
SLPI secretory leukocyte peptidase inhibitor -0.00990234
DSG3 desmoglein 3 -0.00985301
MT1X metallothionein 1X -0.00982182
HOPX HOP homeobox -0.00979665
CYB5R2 cytochrome b5 reductase 2 -0.00979607
S100A8 S100 calcium binding protein A8 -0.00974639
MT1F metallothionein 1F -0.00973177
RETREG1 reticulophagy regulator 1 -0.00969626
KRT23 keratin 23, type I -0.00966484
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.0095979
PSAT1 phosphoserine aminotransferase 1 -0.00959125
STMN2 stathmin 2 -0.00955737
S100A9 S100 calcium binding protein A9 -0.00950146
CYBA cytochrome b-245, alpha polypeptide -0.00944478
IFRD2 interferon-related developmental regulator 2 -0.00943468
KLK10 kallikrein-related peptidase 10 -0.00932276
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00931058
CFD complement factor D (adipsin) -0.0092944
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.0092684
MTUS1 microtubule associated tumor suppressor 1 -0.00926499
LYZ lysozyme -0.0092575
NNMT nicotinamide N-methyltransferase -0.00925091
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0092262
WASHC4 WASH complex subunit 4 -0.0092138
CFH complement factor H -0.00920178
SSBP2 single-stranded DNA binding protein 2 -0.00918074
PIP prolactin-induced protein -0.00910666
CCN2 cellular communication network factor 2 -0.00910432
PDGFRL platelet-derived growth factor receptor-like -0.00905412
HOXC6 homeobox C6 -0.00901485
INSR insulin receptor -0.00896767
COQ8A coenzyme Q8A -0.00894852
CTSG cathepsin G -0.00879129
RET ret proto-oncogene -0.00877226
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00874151
EGR3 early growth response 3 -0.0087326
GLTP glycolipid transfer protein -0.00868035
LMO2 LIM domain only 2 (rhombotin-like 1) -0.0086563
C1S complement component 1, s subcomponent -0.00863916
L1CAM L1 cell adhesion molecule -0.00861905
SPRR2B small proline-rich protein 2B -0.00857561
SPRR3 small proline-rich protein 3 -0.00856544
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00855966
MT1H metallothionein 1H -0.0085378
OPHN1 oligophrenin 1 -0.00845436
EIF5A eukaryotic translation initiation factor 5A -0.00843727
SCGB1D2 secretoglobin, family 1D, member 2 -0.00841355
FBLN2 fibulin 2 -0.0083615
PI3 peptidase inhibitor 3, skin-derived -0.00835817
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00826404
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00826294
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00825982
LY6D lymphocyte antigen 6 complex, locus D -0.00824746
ESRP1 epithelial splicing regulatory protein 1 -0.00824663
RHCG Rh family, C glycoprotein -0.00819212
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00816274
ACKR3 atypical chemokine receptor 3 -0.00815225
CD36 CD36 molecule (thrombospondin receptor) -0.00815124
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00811899
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00811812
COL14A1 collagen, type XIV, alpha 1 -0.00811779
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00811552
LRRN3 leucine rich repeat neuronal 3 -0.00811072
PPL periplakin -0.00808411
TWF2 twinfilin actin binding protein 2 -0.00805339
THBS4 thrombospondin 4 -0.00802132
RASA4 RAS p21 protein activator 4 -0.00799705
OLFM1 olfactomedin 1 -0.00794984
SPRR1B small proline-rich protein 1B -0.00793991
FKBP5 FK506 binding protein 5 -0.00793883
ECM1 extracellular matrix protein 1 -0.00792178
AREG amphiregulin -0.007917
BMP4 bone morphogenetic protein 4 -0.0078648
DEFB1 defensin, beta 1 -0.00784651
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00784623
SEPP1 selenoprotein P, plasma, 1 -0.00782594
LMCD1 LIM and cysteine-rich domains 1 -0.00782204
TPM2 tropomyosin 2 (beta) -0.00780663
BEX1 brain expressed, X-linked 1 -0.00780645
CHRDL1 chordin-like 1 -0.00778705
ELANE elastase, neutrophil expressed -0.00775491
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.0077537
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -0.00772056
APOD apolipoprotein D -0.00769816
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.0076888
HSPB1 heat shock 27kDa protein 1 -0.00768741
PRPH peripherin -0.00766875
DAXX death-domain associated protein -0.00766019
ITGA6 integrin, alpha 6 -0.00762637
SYBU syntabulin (syntaxin-interacting) -0.00760342
PLSCR4 phospholipid scramblase 4 -0.00758529
RUVBL1 RuvB-like AAA ATPase 1 -0.00756162
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00755737
MEN1 multiple endocrine neoplasia I -0.00748282
CLIC5 chloride intracellular channel 5 -0.0074756
RGS5 regulator of G-protein signaling 5 -0.00747257
FSTL1 follistatin-like 1 -0.00746673
PADI2 peptidyl arginine deiminase, type II -0.0074619
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00746135
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00745503
MT1HL1 metallothionein 1H-like 1 -0.00742478
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00741135
PEBP1 phosphatidylethanolamine binding protein 1 -0.00740771
C1R complement component 1, r subcomponent -0.00740672
PLIN3 perilipin 3 -0.00740635
KLF6 Kruppel-like factor 6 -0.00739388
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00737012
PCOLCE procollagen C-endopeptidase enhancer -0.00735738
MFAP4 microfibrillar-associated protein 4 -0.00734135
MPO myeloperoxidase -0.00733276
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00731062
LIMCH1 LIM and calponin homology domains 1 -0.0072997
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0072757
SYNM synemin, intermediate filament protein -0.00725793
MYBPC1 myosin binding protein C, slow type -0.0072424
ANXA1 annexin A1 -0.0072406
RHOF ras homolog family member F (in filopodia) -0.00722082
OXTR oxytocin receptor -0.00720357
PTGES prostaglandin E synthase -0.00720326
ATP10B ATPase, class V, type 10B -0.007203
CSTA cystatin A (stefin A) -0.00720202
CALML5 calmodulin-like 5 -0.00717148
KLK7 kallikrein-related peptidase 7 -0.00716756
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00716505
EDN3 endothelin 3 -0.00715481
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00715237
MT1E metallothionein 1E -0.00713049
PDZK1IP1 PDZK1 interacting protein 1 -0.00712176
S100A12 S100 calcium binding protein A12 -0.00710367
TRIM16 tripartite motif containing 16 -0.00709129
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00708995
ISG20 interferon stimulated exonuclease gene 20kDa -0.00707957
TENT5A terminal nucleotidyltransferase 5A -0.00707828
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.00706565
HSPA2 heat shock 70kDa protein 2 -0.00706119
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00705566
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00704949
TNNC1 troponin C type 1 (slow) -0.00703763
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00702995
LCN2 lipocalin 2 -0.00699104
ADRA2A adrenoceptor alpha 2A -0.00697027
PRDX2 peroxiredoxin 2 -0.00694984
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.0069314
DEFB4A defensin, beta 4A -0.00692645
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00691169
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00690693
COX5A cytochrome c oxidase subunit Va -0.00690474
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00687046
STOM stomatin -0.00684382
SCGB2A1 secretoglobin, family 2A, member 1 -0.00682681
ZNF185 zinc finger protein 185 (LIM domain) -0.00682491
FABP7 fatty acid binding protein 7, brain -0.00680467
AHNAK2 AHNAK nucleoprotein 2 -0.00679308
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00679294
GREM1 gremlin 1, DAN family BMP antagonist -0.0067843
TCTN2 tectonic family member 2 -0.00675337
TESC tescalcin -0.00675056
TPD52L1 tumor protein D52-like 1 -0.00674529
NUTF2 nuclear transport factor 2 -0.00674252
SCD5 stearoyl-CoA desaturase 5 -0.00673815
APLP1 amyloid beta (A4) precursor-like protein 1 -0.00673178
CCNA2 cyclin A2 -0.00672065
TPPP3 tubulin polymerization-promoting protein family member 3 -0.0067025
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00665351
MEOX2 mesenchyme homeobox 2 -0.00663964
SORBS3 sorbin and SH3 domain containing 3 -0.00663581
C3 complement component 3 -0.0066191
GSTP1 glutathione S-transferase pi 1 -0.00661849
TNNT1 troponin T type 1 (skeletal, slow) -0.00660561
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00659962
ASF1B anti-silencing function 1B histone chaperone -0.00659076
RRAGD Ras-related GTP binding D -0.00658544
KLK6 kallikrein-related peptidase 6 -0.00656311
SRPX sushi-repeat containing protein, X-linked -0.0065621
CLC Charcot-Leyden crystal galectin -0.00655295
GUSBP3 glucuronidase, beta pseudogene 3 -0.00654267
ZMAT3 zinc finger, matrin-type 3 -0.00653073
COLEC11 collectin sub-family member 11 -0.0065285
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00652158
BMP7 bone morphogenetic protein 7 -0.00651553
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0065026
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0064856
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00647749
COL15A1 collagen, type XV, alpha 1 -0.00647648
PLPP2 phospholipid phosphatase 2 -0.00647209
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.00646755
ADGRG6 adhesion G protein-coupled receptor G6 -0.00646596
PDE4B phosphodiesterase 4B, cAMP-specific -0.00645132
PERP PERP, TP53 apoptosis effector -0.0064348
AOX1 aldehyde oxidase 1 -0.00642933
BMP6 bone morphogenetic protein 6 -0.0064291
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.00642879
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00639249
CD82 CD82 molecule -0.00637964
TRH thyrotropin-releasing hormone -0.0063763
BAG1 BCL2-associated athanogene -0.00637268
RBBP4 retinoblastoma binding protein 4 -0.0063669
THBS2 thrombospondin 2 -0.00635961
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00634184
DSG1 desmoglein 1 -0.00633902
ARHGAP29 Rho GTPase activating protein 29 -0.00632563
KLF5 Kruppel-like factor 5 (intestinal) -0.0062921
NOVA1 neuro-oncological ventral antigen 1 -0.00626231
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00625855
SNAP25 synaptosomal-associated protein, 25kDa -0.00625714
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.0062365
RAB25 RAB25, member RAS oncogene family -0.00623606
KRT1 keratin 1, type II -0.00622607
KRT20 keratin 20, type I -0.00621901
GPM6B glycoprotein M6B -0.00621509