CDX2 Gene Set

Dataset TRANSFAC Curated Transcription Factor Targets
Category genomics
Type transcription factor
Description caudal type homeobox 2|This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 1045)
External Link http://www.ncbi.nlm.nih.gov/gene/1045
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Genes

255 target genes of the CDX2 transcription factor in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.

Symbol Name
ADAM11 ADAM metallopeptidase domain 11
ADAMTSL1 ADAMTS-like 1
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGBL4 ATP/GTP binding protein-like 4
AGR3 anterior gradient 3
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
AMOT angiomotin
ANGPT1 angiopoietin 1
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
AOC1 amine oxidase, copper containing 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARL4A ADP-ribosylation factor-like 4A
ARX aristaless related homeobox
ASB2 ankyrin repeat and SOCS box containing 2
ASIC5 acid sensing (proton gated) ion channel family member 5
ATP13A4 ATPase type 13A4
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATXN7L1 ataxin 7-like 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BBS1 Bardet-Biedl syndrome 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BNC2 basonuclin 2
BTK Bruton agammaglobulinemia tyrosine kinase
C10ORF107 chromosome 10 open reading frame 107
C10ORF12 chromosome 10 open reading frame 12
C1QTNF7 C1q and tumor necrosis factor related protein 7
C22ORF29 chromosome 22 open reading frame 29
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC68 coiled-coil domain containing 68
CCDC92 coiled-coil domain containing 92
CCER1 coiled-coil glutamate-rich protein 1
CDAN1 codanin 1
CER1 cerberus 1, DAN family BMP antagonist
CFL2 cofilin 2 (muscle)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLTC clathrin, heavy chain (Hc)
CNTLN centlein, centrosomal protein
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB5 cAMP responsive element binding protein 5
CTAGE4 CTAGE family, member 4
CTTNBP2NL CTTNBP2 N-terminal like
CXCL13 chemokine (C-X-C motif) ligand 13
CYB561D1 cytochrome b561 family, member D1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DARS aspartyl-tRNA synthetase
DCAKD dephospho-CoA kinase domain containing
DCHS1 dachsous cadherin-related 1
DLX1 distal-less homeobox 1
DMD dystrophin
DPF3 D4, zinc and double PHD fingers, family 3
DPYD dihydropyrimidine dehydrogenase
DTNA dystrobrevin, alpha
DVL2 dishevelled segment polarity protein 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELP4 elongator acetyltransferase complex subunit 4
EPHA7 EPH receptor A7
EREG epiregulin
FAM91A1 family with sequence similarity 91, member A1
FOXA2 forkhead box A2
FOXD3 forkhead box D3
FOXN3 forkhead box N3
FOXP1 forkhead box P1
FRMD5 FERM domain containing 5
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GCG glucagon
GMPR guanosine monophosphate reductase
GPATCH11 G patch domain containing 11
GPR153 G protein-coupled receptor 153
GRIK3 glutamate receptor, ionotropic, kainate 3
H3F3B H3 histone, family 3B (H3.3B)
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HEXIM1 hexamethylene bis-acetamide inducible 1
HMBOX1 homeobox containing 1
HMGA2 high mobility group AT-hook 2
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HOXA11 homeobox A11
HOXA2 homeobox A2
HOXA3 homeobox A3
HOXA7 homeobox A7
HOXA9 homeobox A9
HOXB3 homeobox B3
HOXB6 homeobox B6
HOXC10 homeobox C10
HOXC12 homeobox C12
HOXC4 homeobox C4
HOXC6 homeobox C6
HOXD3 homeobox D3
HOXD9 homeobox D9
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
HTN1 histatin 1
IFIH1 interferon induced with helicase C domain 1
IGSF22 immunoglobulin superfamily, member 22
IKZF2 IKAROS family zinc finger 2 (Helios)
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
INPPL1 inositol polyphosphate phosphatase-like 1
INS insulin
IRX4 iroquois homeobox 4
IRX6 iroquois homeobox 6
JAG1 jagged 1
KCTD15 potassium channel tetramerization domain containing 15
KCTD4 potassium channel tetramerization domain containing 4
KDM6A lysine (K)-specific demethylase 6A
KIAA1549L KIAA1549-like
KIF1C kinesin family member 1C
KRT20 keratin 20, type I
KRT36 keratin 36, type I
LEPR leptin receptor
LEPROT leptin receptor overlapping transcript
LHX6 LIM homeobox 6
LINC00670 long intergenic non-protein coding RNA 670
LMO3 LIM domain only 3 (rhombotin-like 2)
LOX lysyl oxidase
LPL lipoprotein lipase
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP2 low density lipoprotein receptor-related protein 2
LSAMP limbic system-associated membrane protein
LUC7L LUC7-like (S. cerevisiae)
LY6G6E lymphocyte antigen 6 complex, locus G6E (pseudogene)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K5 mitogen-activated protein kinase kinase 5
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MBNL1 muscleblind-like splicing regulator 1
MBNL2 muscleblind-like splicing regulator 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP7 matrix metallopeptidase 7
MN1 meningioma (disrupted in balanced translocation) 1
MNT MAX network transcriptional repressor
MRFAP1 Morf4 family associated protein 1
MZB1 marginal zone B and B1 cell-specific protein
NAV3 neuron navigator 3
NCKAP5 NCK-associated protein 5
NCOR1 nuclear receptor corepressor 1
NDRG3 NDRG family member 3
NEO1 neogenin 1
NFIB nuclear factor I/B
NHLH2 nescient helix loop helix 2
NID2 nidogen 2 (osteonidogen)
NKRF NFKB repressing factor
NKX6-1 NK6 homeobox 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NMT1 N-myristoyltransferase 1
NPVF neuropeptide VF precursor
NR6A1 nuclear receptor subfamily 6, group A, member 1
NREP neuronal regeneration related protein
NRP1 neuropilin 1
NRXN1 neurexin 1
NTF3 neurotrophin 3
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX1 paired box 1
PAX6 paired box 6
PCDH7 protocadherin 7
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PDAP1 PDGFA associated protein 1
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDZRN4 PDZ domain containing ring finger 4
PGBD3 piggyBac transposable element derived 3
PHF21A PHD finger protein 21A
PHOX2B paired-like homeobox 2b
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLAG1 pleiomorphic adenoma gene 1
PLAGL2 pleiomorphic adenoma gene-like 2
PLSCR4 phospholipid scramblase 4
PMF1 polyamine-modulated factor 1
PNMA1 paraneoplastic Ma antigen 1
PNRC1 proline-rich nuclear receptor coactivator 1
POFUT1 protein O-fucosyltransferase 1
POU3F3 POU class 3 homeobox 3
POU4F2 POU class 4 homeobox 2
POU4F3 POU class 4 homeobox 3
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRDM1 PR domain containing 1, with ZNF domain
PRDX5 peroxiredoxin 5
PRPH peripherin
PTGES2 prostaglandin E synthase 2
PTH1R parathyroid hormone 1 receptor
PTPRR protein tyrosine phosphatase, receptor type, R
RAX retina and anterior neural fold homeobox
RGN regucalcin
RIMS2 regulating synaptic membrane exocytosis 2
RNASEH2C ribonuclease H2, subunit C
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL38 ribosomal protein L38
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SCML1 sex comb on midleg-like 1 (Drosophila)
SERTAD4 SERTA domain containing 4
SESTD1 SEC14 and spectrin domains 1
SEZ6 seizure related 6 homolog (mouse)
SI sucrase-isomaltase (alpha-glucosidase)
SKIDA1 SKI/DACH domain containing 1
SKP1 S-phase kinase-associated protein 1
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLIT3 slit homolog 3 (Drosophila)
SMAD1 SMAD family member 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX14 SRY (sex determining region Y)-box 14
SOX4 SRY (sex determining region Y)-box 4
SRPK2 SRSF protein kinase 2
SSBP3 single stranded DNA binding protein 3
STAG1 stromal antigen 1
SUMO4 small ubiquitin-like modifier 4
SYTL2 synaptotagmin-like 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TASP1 taspase, threonine aspartase, 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX5 T-box 5
TCF21 transcription factor 21
TEKT3 tektin 3
TLE4 transducin-like enhancer of split 4
TMEM126B transmembrane protein 126B
TMOD4 tropomodulin 4 (muscle)
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TOB1 transducer of ERBB2, 1
TRERF1 transcriptional regulating factor 1
TRIM2 tripartite motif containing 2
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TSPYL2 TSPY-like 2
TTC12 tetratricopeptide repeat domain 12
TWIST1 twist family bHLH transcription factor 1
UBE2C ubiquitin-conjugating enzyme E2C
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
VANGL1 VANGL planar cell polarity protein 1
VIS1 viral integration site 1
VIT vitrin
VLDLR very low density lipoprotein receptor
VWA7 von Willebrand factor A domain containing 7
WDR47 WD repeat domain 47
WNT8B wingless-type MMTV integration site family, member 8B
WSB2 WD repeat and SOCS box containing 2
XPO7 exportin 7
ZBTB10 zinc finger and BTB domain containing 10
ZFPM2 zinc finger protein, FOG family member 2
ZIC4 Zic family member 4
ZMYM4 zinc finger, MYM-type 4
ZNF362 zinc finger protein 362
ZRANB1 zinc finger, RAN-binding domain containing 1