CEBPA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description CCAAT/enhancer binding protein (C/EBP), alpha|This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 1050)
External Link http://www.ncbi.nlm.nih.gov/gene/1050
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Genes

114 interacting proteins for CEBPA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTN1 actinin, alpha 1
AK5 adenylate kinase 5
AKAP9 A kinase (PRKA) anchor protein 9
AR androgen receptor
ASXL1 additional sex combs like transcriptional regulator 1
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATF5 activating transcription factor 5
ATF7 activating transcription factor 7
BATF basic leucine zipper transcription factor, ATF-like
BATF2 basic leucine zipper transcription factor, ATF-like 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BHLHE41 basic helix-loop-helix family, member e41
C1QBP complement component 1, q subcomponent binding protein
CAPN2 calpain 2, (m/II) large subunit
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CDX1 caudal type homeobox 1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHD1 chromodomain helicase DNA binding protein 1
CREB5 cAMP responsive element binding protein 5
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DBP D site of albumin promoter (albumin D-box) binding protein
DDIT3 DNA-damage-inducible transcript 3
E2F4 E2F transcription factor 4, p107/p130-binding
EDF1 endothelial differentiation-related factor 1
ELAVL1 ELAV like RNA binding protein 1
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GATA2 GATA binding protein 2
GFAP glial fibrillary acidic protein
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
MACF1 microtubule-actin crosslinking factor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAX MYC associated factor X
MCM5 minichromosome maintenance complex component 5
MNT MAX network transcriptional repressor
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSX2 msh homeobox 2
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NCOA6 nuclear receptor coactivator 6
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFYA nuclear transcription factor Y, alpha
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARP1 poly (ADP-ribose) polymerase 1
PGAM1 phosphoglycerate mutase 1 (brain)
PIAS1 protein inhibitor of activated STAT, 1
PKN2 protein kinase N2
POLR1E polymerase (RNA) I polypeptide E, 53kDa
RAB34 RAB34, member RAS oncogene family
RANBP2 RAN binding protein 2
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RB1 retinoblastoma 1
RBL1 retinoblastoma-like 1
RFC1 replication factor C (activator 1) 1, 145kDa
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RUNX1 runt-related transcription factor 1
SFPQ splicing factor proline/glutamine-rich
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SOX10 SRY (sex determining region Y)-box 10
SOX8 SRY (sex determining region Y)-box 8
SP110 SP110 nuclear body protein
SPI1 Spi-1 proto-oncogene
SPTBN1 spectrin, beta, non-erythrocytic 1
SRA1 steroid receptor RNA activator 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TFDP1 transcription factor Dp-1
TGFB2 transforming growth factor, beta 2
TRA2B transformer 2 beta homolog (Drosophila)
UBC ubiquitin C
UBE3A ubiquitin protein ligase E3A
UBTF upstream binding transcription factor, RNA polymerase I
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YY1AP1 YY1 associated protein 1
ZBTB16 zinc finger and BTB domain containing 16
ZEB2 zinc finger E-box binding homeobox 2
ZNF45 zinc finger protein 45