CEBPD Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description CCAAT/enhancer binding protein (C/EBP), delta|The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 1052)
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Genes

342 genes differentially expressed following the CEBPD gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GGT5 gamma-glutamyltransferase 5 3.07274
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.07274
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 3.07274
SCG2 secretogranin II 3.07274
GPR55 G protein-coupled receptor 55 3.07274
GPR52 G protein-coupled receptor 52 3.07274
RXFP2 relaxin/insulin-like family peptide receptor 2 3.07274
BTC betacellulin 3.07274
SLC35G5 solute carrier family 35, member G5 3.07274
OR10A3 olfactory receptor, family 10, subfamily A, member 3 3.07274
PERM1 PPARGC1 and ESRR induced regulator, muscle 1 3.07274
CD6 CD6 molecule 3.07274
FOLR1 folate receptor 1 (adult) 3.07274
RHOXF2 Rhox homeobox family, member 2 3.07274
RAB44 RAB44, member RAS oncogene family 3.07274
OR5H1 olfactory receptor, family 5, subfamily H, member 1 3.07274
TM6SF1 transmembrane 6 superfamily member 1 3.07274
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.07274
OR2A1 olfactory receptor, family 2, subfamily A, member 1 3.07274
FPR2 formyl peptide receptor 2 3.07274
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.07274
CFHR3 complement factor H-related 3 3.07274
SIX1 SIX homeobox 1 3.07274
MUC5B mucin 5B, oligomeric mucus/gel-forming 3.07274
FOXR1 forkhead box R1 3.07274
DSG3 desmoglein 3 3.07274
OCSTAMP osteoclast stimulatory transmembrane protein 3.07274
F2 coagulation factor II (thrombin) 3.07274
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 3.07274
FAM216B family with sequence similarity 216, member B 3.07274
DIO3 deiodinase, iodothyronine, type III 3.07274
PRDM12 PR domain containing 12 3.07274
LDHC lactate dehydrogenase C 3.07274
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 3.07274
FAM81B family with sequence similarity 81, member B 3.07274
DHRS9 dehydrogenase/reductase (SDR family) member 9 3.07274
C1QB complement component 1, q subcomponent, B chain 3.07274
PTGER3 prostaglandin E receptor 3 (subtype EP3) 3.07274
PTH2 parathyroid hormone 2 3.07274
FOLR2 folate receptor 2 (fetal) 3.07274
RPE65 retinal pigment epithelium-specific protein 65kDa 3.07274
SSTR5 somatostatin receptor 5 3.07274
SSTR3 somatostatin receptor 3 3.07274
NUGGC nuclear GTPase, germinal center associated 3.07274
SPINT3 serine peptidase inhibitor, Kunitz type, 3 3.07274
REN renin 3.07274
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 3.07274
GADL1 glutamate decarboxylase-like 1 3.07274
TWIST1 twist family bHLH transcription factor 1 3.07274
ARL5C ADP-ribosylation factor-like 5C 3.07274
CPNE8-AS1 CPNE8 antisense RNA 1 3.07274
CES4A carboxylesterase 4A 3.07274
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 3.07274
ALDOA aldolase A, fructose-bisphosphate 3.07274
GBP2 guanylate binding protein 2, interferon-inducible 3.07274
ZAR1 zygote arrest 1 3.07274
TBC1D3L TBC1 domain family, member 3L 3.07274
ASB5 ankyrin repeat and SOCS box containing 5 3.07274
ASB4 ankyrin repeat and SOCS box containing 4 3.07274
BDKRB1 bradykinin receptor B1 3.07274
SPATA22 spermatogenesis associated 22 3.07274
H2BC1 H2B clustered histone 1 3.07274
ASDURF ASNSD1 upstream open reading frame 3.07274
SPMIP3 sperm microtubule inner protein 3 3.07274
CIMAP1D CIMAP1 family member D 3.07274
GREP1 glycine rich extracellular protein 1 3.07274
SMIM43 small integral membrane protein 43 3.07274
MINDY4B MINDY family member 4B 3.07274
GARIN6 golgi associated RAB2 interactor family member 6 3.07274
DUSP29 dual specificity phosphatase 29 3.07274
FLACC1 flagellum associated containing coiled-coil domains 1 3.07274
PLPP4 phospholipid phosphatase 4 3.07274
VEGFD vascular endothelial growth factor D 3.07274
SELL selectin L 3.07274
DYNLRB2 dynein, light chain, roadblock-type 2 3.07274
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 3.07274
BARX2 BARX homeobox 2 3.07274
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 3.07274
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.07274
RASAL3 RAS protein activator like 3 3.07274
PROX2 prospero homeobox 2 3.07274
PRRT4 proline-rich transmembrane protein 4 3.07274
LEF1 lymphoid enhancer-binding factor 1 3.07274
TLR7 toll-like receptor 7 3.07274
NHLRC4 NHL repeat containing 4 3.07274
NPIPB9 nuclear pore complex interacting protein family, member B9 3.07274
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.07274
SAMD11 sterile alpha motif domain containing 11 3.07274
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.07274
GATA6 GATA binding protein 6 3.07274
MROH5 maestro heat-like repeat family member 5 3.07274
CCDC42 coiled-coil domain containing 42 3.07274
HNF1A HNF1 homeobox A 3.07274
ASIC4 acid sensing (proton gated) ion channel family member 4 3.07274
TMEM119 transmembrane protein 119 3.07274
LRRC72 leucine rich repeat containing 72 3.07274
TAS1R1 taste receptor, type 1, member 1 3.07274
FGFBP1 fibroblast growth factor binding protein 1 3.07274
CLDN5 claudin 5 3.07274
KLK7 kallikrein-related peptidase 7 3.07274
B9D2 B9 protein domain 2 3.07274
EFCAB3 EF-hand calcium binding domain 3 3.07274
RAD51AP2 RAD51 associated protein 2 3.07274
LHX2 LIM homeobox 2 3.07274
KCNK9 potassium channel, two pore domain subfamily K, member 9 3.07274
A3GALT2 alpha 1,3-galactosyltransferase 2 3.07274
GP1BB glycoprotein Ib (platelet), beta polypeptide 3.07274
TYR tyrosinase 3.07274
PMP2 peripheral myelin protein 2 3.07274
PRSS57 protease, serine, 57 3.07274
IER5L immediate early response 5-like 3.07274
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 3.07274
ACKR2 atypical chemokine receptor 2 3.07274
CARD6 caspase recruitment domain family, member 6 3.07274
POU3F2 POU class 3 homeobox 2 3.07274
SLITRK1 SLIT and NTRK-like family, member 1 3.07274
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.07274
C6ORF163 chromosome 6 open reading frame 163 3.07274
ADORA3 adenosine A3 receptor 3.07274
EGR2 early growth response 2 3.07274
VWA7 von Willebrand factor A domain containing 7 3.07274
RRH retinal pigment epithelium-derived rhodopsin homolog 3.07274
FOXRED1 FAD-dependent oxidoreductase domain containing 1 3.07274
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 3.07274
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.07274
CPA2 carboxypeptidase A2 (pancreatic) 3.07274
AKNAD1 AKNA domain containing 1 3.07274
PTPN20 protein tyrosine phosphatase, non-receptor type 20 3.07274
TF transferrin 3.07274
KLF4 Kruppel-like factor 4 (gut) 3.07274
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.07274
DUOX2 dual oxidase 2 3.07274
ANKRD63 ankyrin repeat domain 63 3.07274
C9ORF64 chromosome 9 open reading frame 64 3.07274
CRYBB3 crystallin, beta B3 3.07274
DLX5 distal-less homeobox 5 3.07274
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 3.07274
NPR3 natriuretic peptide receptor 3 3.07274
CFI complement factor I 3.07274
RXFP1 relaxin/insulin-like family peptide receptor 1 3.07274
NKPD1 NTPase, KAP family P-loop domain containing 1 3.07274
FOXS1 forkhead box S1 3.07274
SPNS3 spinster homolog 3 (Drosophila) 3.07274
LY6G6C lymphocyte antigen 6 complex, locus G6C 3.07274
BTG4 B-cell translocation gene 4 3.07274
ST18 suppression of tumorigenicity 18, zinc finger 3.07274
RP1 retinitis pigmentosa 1 (autosomal dominant) 3.07274
AOC1 amine oxidase, copper containing 1 3.07274
RBP4 retinol binding protein 4, plasma 3.07274
AREG amphiregulin 3.07274
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.07274
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.07274
NEUROD4 neuronal differentiation 4 3.07274
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.07274
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3.07274
NLRP14 NLR family, pyrin domain containing 14 3.07274
A1CF APOBEC1 complementation factor 3.07274
OSR1 odd-skipped related transciption factor 1 3.07274
LAMB4 laminin, beta 4 3.07274
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.07274
CD8A CD8a molecule 3.07274
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 3.07274
CLCA1 chloride channel accessory 1 3.07274
LRRC31 leucine rich repeat containing 31 3.07274
CNGB1 cyclic nucleotide gated channel beta 1 3.07274
AGBL4 ATP/GTP binding protein-like 4 3.07274
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 3.07274
POMC proopiomelanocortin 3.05919
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.97279
TTC6 tetratricopeptide repeat domain 6 2.97279
SPATA18 spermatogenesis associated 18 2.97279
STX19 syntaxin 19 2.97279
ANKRD17 ankyrin repeat domain 17 2.9484
AZGP1 alpha-2-glycoprotein 1, zinc-binding 2.72744
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.72744
ZNF765 zinc finger protein 765 2.66199
USP34 ubiquitin specific peptidase 34 2.66199
CYB5D2 cytochrome b5 domain containing 2 2.62278
RPE ribulose-5-phosphate-3-epimerase 2.61161
FNDC3A fibronectin type III domain containing 3A 2.51433
WAPL WAPL cohesin release factor 2.5056
TPD52L2 tumor protein D52-like 2 2.50233
SCUBE1 signal peptide, CUB domain, EGF-like 1 2.4735
IFRD1 interferon-related developmental regulator 1 2.4692
JAK3 Janus kinase 3 2.46859
TP53 tumor protein p53 2.46807
TEX9 testis expressed 9 2.45948
DCLK3 doublecortin-like kinase 3 2.45813
ZNF384 zinc finger protein 384 2.44287
SUCLG1 succinate-CoA ligase, alpha subunit 2.41907
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.41444
CFAP100 cilia and flagella associated protein 100 2.41444
COBL cordon-bleu WH2 repeat protein 2.38902
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 2.38589
MRPL43 mitochondrial ribosomal protein L43 2.38236
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.35511
CZIB CXXC motif containing zinc binding protein 2.34963
MSL1 male-specific lethal 1 homolog (Drosophila) 2.33941
VRK1 vaccinia related kinase 1 2.33016
GTF2A1 general transcription factor IIA, 1, 19/37kDa 2.32606
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2.32563
MAP9 microtubule-associated protein 9 2.32271
DBN1 drebrin 1 2.30917
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 2.30857
CIART circadian associated repressor of transcription 2.24591
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 2.2438
CERS3 ceramide synthase 3 2.23701
GLTP glycolipid transfer protein 2.23701
DPRX divergent-paired related homeobox 2.23701
RABL2B RAB, member of RAS oncogene family-like 2B 2.20211
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 2.16507
CLDN19 claudin 19 2.16139
C17ORF107 chromosome 17 open reading frame 107 2.15951
ACSS1 acyl-CoA synthetase short-chain family member 1 2.15951
PGAM2 phosphoglycerate mutase 2 (muscle) 2.15951
RIN1 Ras and Rab interactor 1 2.15951
TMEM86A transmembrane protein 86A 2.15951
ADAM9 ADAM metallopeptidase domain 9 2.15951
FOSL2 FOS-like antigen 2 2.15951
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.15951
RAG2 recombination activating gene 2 2.15951
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 2.15951
FANCI Fanconi anemia, complementation group I 2.15951
BIRC6 baculoviral IAP repeat containing 6 2.14776
HELLS helicase, lymphoid-specific 2.14776
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.12567
TRMT5 tRNA methyltransferase 5 2.12111
H3C4 H3 clustered histone 4 2.10232
BTBD9 BTB (POZ) domain containing 9 2.09292
PGS1 phosphatidylglycerophosphate synthase 1 2.09131
SHANK3 SH3 and multiple ankyrin repeat domains 3 2.0845
CFAP144 cilia and flagella associated protein 144 2.05224
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.05224
GPR19 G protein-coupled receptor 19 2.03837
CLDND2 claudin domain containing 2 2.02916
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 2.01654
TRIP6 thyroid hormone receptor interactor 6 2.01654
TONSL tonsoku-like, DNA repair protein 2.01542

decreased expression

Symbol Name Standardized Value
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 -3.07274
MROH9 maestro heat-like repeat family member 9 -3.07274
SYNPO2L synaptopodin 2-like -3.07274
CXCL17 chemokine (C-X-C motif) ligand 17 -3.07274
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -3.07274
MAPT microtubule-associated protein tau -3.07274
FGF1 fibroblast growth factor 1 (acidic) -3.07274
ASB16 ankyrin repeat and SOCS box containing 16 -3.07274
C16ORF89 chromosome 16 open reading frame 89 -3.07274
PODNL1 podocan-like 1 -3.07274
ZNF532 zinc finger protein 532 -3.07274
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -3.07274
LNPEP leucyl/cystinyl aminopeptidase -2.97279
FAM3D family with sequence similarity 3, member D -2.9484
FNDC11 fibronectin type III domain containing 11 -2.9484
TSHR thyroid stimulating hormone receptor -2.9484
PRSS21 protease, serine, 21 (testisin) -2.9484
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.9484
EMCN endomucin -2.9484
SQOR sulfide quinone oxidoreductase -2.9484
CPLX1 complexin 1 -2.9484
LGALS9 lectin, galactoside-binding, soluble, 9 -2.9484
LOC114841035 uncharacterized LOC114841035 -2.9484
FAM89A family with sequence similarity 89, member A -2.9484
SPI1 Spi-1 proto-oncogene -2.9484
MLANA melan-A -2.9484
SP140 SP140 nuclear body protein -2.9484
ZNF467 zinc finger protein 467 -2.9484
CCDC17 coiled-coil domain containing 17 -2.9484
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -2.9484
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) -2.9484
FAM209B family with sequence similarity 209, member B -2.9484
FNDC1 fibronectin type III domain containing 1 -2.9484
AMIGO1 adhesion molecule with Ig-like domain 1 -2.9484
ZMYND15 zinc finger, MYND-type containing 15 -2.9484
CFAP47 cilia and flagella associated protein 47 -2.9484
ZNF674 zinc finger protein 674 -2.9484
PRSS51 protease, serine, 51 -2.9484
GTF2A1L general transcription factor IIA, 1-like -2.9484
MST1 macrophage stimulating 1 -2.9484
CTSO cathepsin O -2.9484
DMRT1 doublesex and mab-3 related transcription factor 1 -2.9484
CLPSL1 colipase-like 1 -2.9484
PCDHGA1 protocadherin gamma subfamily A, 1 -2.9484
GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 -2.88459
MAGEL2 melanoma antigen family L2 -2.85301
IL6ST-DT IL6ST divergent transcript -2.78211
CC2D2A coiled-coil and C2 domain containing 2A -2.68377
COX20 COX20 cytochrome c oxidase assembly factor -2.52797
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.51626
ZNF641 zinc finger protein 641 -2.5056
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.50233
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.4707
PPP1R12C protein phosphatase 1, regulatory subunit 12C -2.46807
ATRIP ATR interacting protein -2.46192
CNGA4 cyclic nucleotide gated channel alpha 4 -2.45813
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -2.45813
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -2.45813
TRIM34 tripartite motif containing 34 -2.45813
DUSP28 dual specificity phosphatase 28 -2.45813
TMEM220 transmembrane protein 220 -2.45813
IFIH1 interferon induced with helicase C domain 1 -2.45813
MT2A metallothionein 2A -2.45606
RPN1 ribophorin I -2.45407
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 -2.443
NIT1 nitrilase 1 -2.443
KANSL2 KAT8 regulatory NSL complex subunit 2 -2.4394
SOAT1 sterol O-acyltransferase 1 -2.4381
SHROOM1 shroom family member 1 -2.4381
ZNF469 zinc finger protein 469 -2.36068
SNU13 small nuclear ribonucleoprotein 13 -2.35855
CLK1 CDC-like kinase 1 -2.32305
GSTO1 glutathione S-transferase omega 1 -2.32015
ACHE acetylcholinesterase (Yt blood group) -2.30917
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.28536
NET1 neuroepithelial cell transforming 1 -2.28115
EIF5 eukaryotic translation initiation factor 5 -2.27606
TMED2 transmembrane emp24 domain trafficking protein 2 -2.27195
AMPD3 adenosine monophosphate deaminase 3 -2.2619
ISG15 ISG15 ubiquitin-like modifier -2.26161
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -2.25903
AKAP8L A kinase (PRKA) anchor protein 8-like -2.25552
ZNF221 zinc finger protein 221 -2.25098
PROKR1 prokineticin receptor 1 -2.25098
ACVR1C activin A receptor, type IC -2.25098
LEAP2 liver expressed antimicrobial peptide 2 -2.23793
INTS15 integrator complex subunit 15 -2.20588
LAT linker for activation of T cells -2.20588
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 -2.20211
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.17518
POGLUT3 protein O-glucosyltransferase 3 -2.16889
OLFM2 olfactomedin 2 -2.14743
SNX11 sorting nexin 11 -2.12341
TSPAN2 tetraspanin 2 -2.10813
HPS1 Hermansky-Pudlak syndrome 1 -2.09894
SLC43A3 solute carrier family 43, member 3 -2.0923
ITSN2 intersectin 2 -2.05515
LTBP1 latent transforming growth factor beta binding protein 1 -2.04965
ZNF517 zinc finger protein 517 -2.04769
SERTAD2 SERTA domain containing 2 -2.04628
LSG1 large 60S subunit nuclear export GTPase 1 -2.0227
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -2.01511
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 -2.01391
SMIM7 small integral membrane protein 7 -2.00002