CENPA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description centromere protein A|Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1058)
External Link http://www.ncbi.nlm.nih.gov/gene/1058
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83 interacting proteins for CENPA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
CBX3 chromobox homolog 3
CBX8 chromobox homolog 8
CCNB1 cyclin B1
CCNB2 cyclin B2
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CENPB centromere protein B, 80kDa
CENPH centromere protein H
CENPI centromere protein I
CENPK centromere protein K
CENPM centromere protein M
CENPN centromere protein N
CENPO centromere protein O
CENPT centromere protein T
CHAF1A chromatin assembly factor 1, subunit A (p150)
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DIAPH1 diaphanous-related formin 1
DIAPH2 diaphanous-related formin 2
DIAPH3 diaphanous-related formin 3
DSP desmoplakin
E2F1 E2F transcription factor 1
EIF4A1 eukaryotic translation initiation factor 4A1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FBL fibrillarin
FLNA filamin A, alpha
FYN FYN proto-oncogene, Src family tyrosine kinase
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
H2AFZ H2A histone family, member Z
H3F3A H3 histone, family 3A
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H2AB histone cluster 1, H2ab
HIST1H2AD histone cluster 1, H2ad
HIST1H2BB histone cluster 1, H2bb
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AC histone cluster 2, H2ac
HIST2H2BE histone cluster 2, H2be
HIST3H2BB histone cluster 3, H2bb
HJURP Holliday junction recognition protein
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPA8 heat shock 70kDa protein 8
INCENP inner centromere protein antigens 135/155kDa
KIAA1429 KIAA1429
KIF23 kinesin family member 23
LMO7 LIM domain 7
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PHIP pleckstrin homology domain interacting protein
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RING1 ring finger protein 1
RNF2 ring finger protein 2
RPA1 replication protein A1, 70kDa
RSF1 remodeling and spacing factor 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SHCBP1 SHC SH2-domain binding protein 1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SRRT serrate, RNA effector molecule
SSRP1 structure specific recognition protein 1
STAG2 stromal antigen 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
WTAP Wilms tumor 1 associated protein
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZC3H13 zinc finger CCCH-type containing 13
ZFP91 ZFP91 zinc finger protein