CENPE Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description centromere protein E, 312kDa|Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014] (NCBI Entrez Gene Database, 1062)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_CENPE
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Genes

41 co-expressed genes for CENPE from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CCNB2 cyclin B2
CCNF cyclin F
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FOXM1 forkhead box M1
H2AFX H2A histone family, member X
HMMR hyaluronan-mediated motility receptor (RHAMM)
KIF11 kinesin family member 11
KIF18B kinesin family member 18B
MKI67 marker of proliferation Ki-67
MT1JP metallothionein 1J, pseudogene
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NDC80 NDC80 kinetochore complex component
NUSAP1 nucleolar and spindle associated protein 1
PCNA proliferating cell nuclear antigen
PRC1 protein regulator of cytokinesis 1
PRIM1 primase, DNA, polypeptide 1 (49kDa)
RFC3 replication factor C (activator 1) 3, 38kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SHCBP1 SHC SH2-domain binding protein 1
SMC2 structural maintenance of chromosomes 2
TMPO thymopoietin
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZWINT ZW10 interacting kinetochore protein