| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | centrosomal protein 170kDa|The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9859) |
| External Link | https://ncbi.nlm.nih.gov/gene/9859 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CEP170 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0223822 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.020668 |
| OLFM4 | olfactomedin 4 | 0.0186986 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0173742 |
| HTRA1 | HtrA serine peptidase 1 | 0.0167957 |
| FABP1 | fatty acid binding protein 1, liver | 0.0154623 |
| METTL7A | methyltransferase like 7A | 0.0153781 |
| SDC1 | syndecan 1 | 0.0153617 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.0150599 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0145115 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0142686 |
| CLCA1 | chloride channel accessory 1 | 0.0140255 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0139161 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0135111 |
| AOC1 | amine oxidase, copper containing 1 | 0.0134242 |
| RPA3 | replication protein A3, 14kDa | 0.0133295 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.0131984 |
| PLK1 | polo-like kinase 1 | 0.0128627 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0128312 |
| ADIRF | adipogenesis regulatory factor | 0.0127858 |
| CCNF | cyclin F | 0.012641 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0124855 |
| BRCA1 | breast cancer 1, early onset | 0.0124821 |
| PITX3 | paired-like homeodomain 3 | 0.0124248 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.0122654 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.0122017 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.012156 |
| ICAM2 | intercellular adhesion molecule 2 | 0.0121078 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.0121046 |
| THBS1 | thrombospondin 1 | 0.0119626 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.0119535 |
| TMEM38B | transmembrane protein 38B | 0.011908 |
| LEFTY1 | left-right determination factor 1 | 0.0118953 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0117424 |
| IFRD2 | interferon-related developmental regulator 2 | 0.0116717 |
| FST | follistatin | 0.0116585 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0115458 |
| CDC20 | cell division cycle 20 | 0.0115412 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.0114486 |
| TXNDC9 | thioredoxin domain containing 9 | 0.011354 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0112576 |
| PLPBP | pyridoxal phosphate binding protein | 0.0112574 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0112322 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.0111072 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.0109752 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0109153 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.0108616 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.010818 |
| AGTR1 | angiotensin II receptor, type 1 | 0.0107647 |
| FCGBP | Fc fragment of IgG binding protein | 0.0107007 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0106917 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.0106187 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.0105935 |
| KRT20 | keratin 20, type I | 0.0104745 |
| LRRC17 | leucine rich repeat containing 17 | 0.0104086 |
| SELENOW | selenoprotein W | 0.010398 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.0103939 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.0103746 |
| DPEP1 | dipeptidase 1 (renal) | 0.010274 |
| ADD3 | adducin 3 (gamma) | 0.0102563 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.0102354 |
| PLN | phospholamban | 0.010195 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.0101831 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0101383 |
| ERLIN2 | ER lipid raft associated 2 | 0.0101002 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0100979 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.0100894 |
| LAGE3 | L antigen family, member 3 | 0.0100763 |
| WDR7 | WD repeat domain 7 | 0.0100088 |
| DIPK1A | divergent protein kinase domain 1A | 0.0099704 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.009926 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00992186 |
| SRGN | serglycin | 0.00980572 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00979229 |
| HBD | hemoglobin, delta | 0.00978067 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.00970935 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00961913 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00959986 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 0.00959175 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00959098 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00956714 |
| CA12 | carbonic anhydrase XII | 0.0095498 |
| H1-10 | H1.10 linker histone | 0.0095457 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.0095318 |
| CDCA4 | cell division cycle associated 4 | 0.00950331 |
| EAF2 | ELL associated factor 2 | 0.00949667 |
| SURF1 | surfeit 1 | 0.00942612 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.00937829 |
| AREG | amphiregulin | 0.00937367 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00931392 |
| CRYM | crystallin, mu | 0.00929072 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.00927764 |
| TMEM160 | transmembrane protein 160 | 0.00926519 |
| TSPAN7 | tetraspanin 7 | 0.00926375 |
| NNMT | nicotinamide N-methyltransferase | 0.0092603 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00925581 |
| REG1B | regenerating islet-derived 1 beta | 0.00924873 |
| DAXX | death-domain associated protein | 0.00923449 |
| C21ORF33 | chromosome 21 open reading frame 33 | 0.00923348 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00921202 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00919375 |
| CD320 | CD320 molecule | 0.0091134 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00910526 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00905951 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00905747 |
| CENPX | centromere protein X | 0.00905076 |
| CLC | Charcot-Leyden crystal galectin | 0.00900515 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00894536 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00894523 |
| WDR61 | WD repeat domain 61 | 0.00887888 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00885569 |
| MMP9 | matrix metallopeptidase 9 | 0.00883288 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00877305 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00876106 |
| COA3 | cytochrome c oxidase assembly factor 3 | 0.00874653 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00874426 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00866829 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.0086541 |
| GPX2 | glutathione peroxidase 2 | 0.00865381 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.00864815 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | 0.00864808 |
| UROS | uroporphyrinogen III synthase | 0.0086432 |
| HMGB3 | high mobility group box 3 | 0.00863052 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00862884 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00862421 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00858593 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | 0.00858366 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00857615 |
| NOTCH1 | notch 1 | 0.00856675 |
| ZNF329 | zinc finger protein 329 | 0.00856225 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00854846 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00853484 |
| NOX1 | NADPH oxidase 1 | 0.00852602 |
| MT1E | metallothionein 1E | 0.00849819 |
| CHEK2 | checkpoint kinase 2 | 0.00846939 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00846762 |
| SCAND1 | SCAN domain containing 1 | 0.00845262 |
| RUVBL2 | RuvB-like AAA ATPase 2 | 0.00845102 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00842888 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00842083 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00839358 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00836909 |
| B3GNT1 | 0.00834078 | |
| DOK5 | docking protein 5 | 0.00832551 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00830905 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00830398 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00825614 |
| LXN | latexin | 0.00825083 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00823457 |
| CRIP2 | cysteine-rich protein 2 | 0.00821963 |
| CD38 | CD38 molecule | 0.00820862 |
| ERI2 | ERI1 exoribonuclease family member 2 | 0.00818707 |
| MLF1 | myeloid leukemia factor 1 | 0.00817372 |
| RGS1 | regulator of G-protein signaling 1 | 0.00816773 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.00815675 |
| LST1 | leukocyte specific transcript 1 | 0.00815658 |
| TSNAX | translin-associated factor X | 0.00815201 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.00814786 |
| LYRM4 | LYR motif containing 4 | 0.00814105 |
| UFSP2 | UFM1-specific peptidase 2 | 0.00812688 |
| SRM | spermidine synthase | 0.00811218 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00810465 |
| CFI | complement factor I | 0.00810453 |
| PIMREG | PICALM interacting mitotic regulator | 0.00809859 |
| LBR | lamin B receptor | 0.00809552 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.00809321 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00809227 |
| CCNA2 | cyclin A2 | 0.0080849 |
| KIF4A | kinesin family member 4A | 0.00808357 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00805483 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00805002 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00804495 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00800681 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0080067 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00797338 |
| RWDD2B | RWD domain containing 2B | 0.007964 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00793854 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | 0.007926 |
| TSPO | translocator protein (18kDa) | 0.00792544 |
| PLAT | plasminogen activator, tissue | 0.00791105 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | 0.00789335 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00788823 |
| FASN | fatty acid synthase | 0.00788323 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00786937 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00784992 |
| ISOC2 | isochorismatase domain containing 2 | 0.00783664 |
| GAS1 | growth arrest-specific 1 | 0.00783387 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00782964 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.00781178 |
| RGS4 | regulator of G-protein signaling 4 | 0.00780734 |
| CREBL2 | cAMP responsive element binding protein-like 2 | 0.00779427 |
| NDUFB11 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa | 0.00778234 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 0.00774667 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00773011 |
| S100A8 | S100 calcium binding protein A8 | 0.00772825 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00772741 |
| LRRC19 | leucine rich repeat containing 19 | 0.00771649 |
| TMEM50B | transmembrane protein 50B | 0.00771413 |
| ZC3H4 | zinc finger CCCH-type containing 4 | 0.00770109 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0076946 |
| FAM162A | family with sequence similarity 162, member A | 0.00767619 |
| TMEM14B | transmembrane protein 14B | 0.00766347 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00765466 |
| LTF | lactotransferrin | 0.00765428 |
| GPER1 | G protein-coupled estrogen receptor 1 | 0.00765308 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.0076462 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.0076414 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00763875 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00763839 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00762685 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00762499 |
| NANOG | Nanog homeobox | 0.00761506 |
| STOM | stomatin | 0.00759658 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00758586 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 0.00756904 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00755899 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 0.00755783 |
| ADI1 | acireductone dioxygenase 1 | 0.00755227 |
| CLIC5 | chloride intracellular channel 5 | 0.00754481 |
| ZG16 | zymogen granule protein 16 | 0.00753967 |
| TYRP1 | tyrosinase-related protein 1 | 0.00753748 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00751997 |
| SIRT5 | sirtuin 5 | 0.00751376 |
| ECHS1 | enoyl CoA hydratase, short chain, 1, mitochondrial | 0.00751304 |
| CBR3 | carbonyl reductase 3 | 0.00751078 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00750731 |
| SLC2A4RG | SLC2A4 regulator | 0.00750696 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | 0.00750588 |
| IFT46 | intraflagellar transport 46 | 0.00749957 |
| RPS5 | ribosomal protein S5 | 0.00748945 |
| JAG2 | jagged 2 | 0.00748405 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00747351 |
| OIP5 | Opa interacting protein 5 | 0.00746347 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00746198 |
| COPS4 | COP9 signalosome subunit 4 | 0.00745194 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.00743567 |
| GLB1 | galactosidase, beta 1 | 0.00740757 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00740108 |
| HPF1 | histone PARylation factor 1 | 0.00739676 |
| JADE2 | jade family PHD finger 2 | 0.00739162 |
| AK4 | adenylate kinase 4 | 0.00738299 |
| HMBS | hydroxymethylbilane synthase | 0.00736213 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00736073 |
| SEH1L | SEH1-like (S. cerevisiae) | 0.00735752 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00735253 |
| CAMP | cathelicidin antimicrobial peptide | 0.00734778 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00733346 |
| RAD51 | RAD51 recombinase | 0.00732287 |
| AHCY | adenosylhomocysteinase | 0.00730815 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00729629 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | -0.0265959 |
| IFI44L | interferon-induced protein 44-like | -0.0247936 |
| MX1 | MX dynamin-like GTPase 1 | -0.0233422 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0203179 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0186789 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0170869 |
| FN1 | fibronectin 1 | -0.0170058 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0169865 |
| IFI44 | interferon-induced protein 44 | -0.0166395 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0160433 |
| YBX3 | Y box binding protein 3 | -0.0158845 |
| HMOX1 | heme oxygenase 1 | -0.0156974 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0150604 |
| XIC | X chromosome inactivation center | -0.0146153 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0145309 |
| DUSP10 | dual specificity phosphatase 10 | -0.0141818 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0141766 |
| HSPB8 | heat shock 22kDa protein 8 | -0.01406 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.0139985 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0138669 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0135371 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.01344 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0133439 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0131366 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0130117 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0129947 |
| GOLGA8A | golgin A8 family, member A | -0.0129579 |
| GNAS | GNAS complex locus | -0.0129263 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.0129136 |
| EGR2 | early growth response 2 | -0.0128278 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0127408 |
| S100A11 | S100 calcium binding protein A11 | -0.0126621 |
| TGM2 | transglutaminase 2 | -0.0124914 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0124486 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0121297 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0120988 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0118939 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0118568 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0117735 |
| GAB2 | GRB2-associated binding protein 2 | -0.0117722 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0117686 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0117252 |
| NIT1 | nitrilase 1 | -0.0117196 |
| IRS2 | insulin receptor substrate 2 | -0.0117133 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0116742 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0116579 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0115646 |
| ANXA3 | annexin A3 | -0.0114995 |
| XAF1 | XIAP associated factor 1 | -0.0114319 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.0114277 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0114011 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0113887 |
| LYST | lysosomal trafficking regulator | -0.0113857 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0113502 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0112101 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | -0.0111666 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0111567 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0111303 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0111117 |
| S100A10 | S100 calcium binding protein A10 | -0.0110648 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0110312 |
| EGR1 | early growth response 1 | -0.0110116 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0109747 |
| JAK1 | Janus kinase 1 | -0.0109004 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0108685 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0108655 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0108469 |
| HLA-B | major histocompatibility complex, class I, B | -0.0108358 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.010815 |
| NELL2 | NEL-like 2 (chicken) | -0.0107747 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.0107595 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0107121 |
| PLK2 | polo-like kinase 2 | -0.0106814 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0106761 |
| CST1 | cystatin SN | -0.0106304 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0106042 |
| KRT7 | keratin 7, type II | -0.0105813 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | -0.0105505 |
| IRF9 | interferon regulatory factor 9 | -0.010539 |
| COPA | coatomer protein complex, subunit alpha | -0.0104496 |
| FNBP1 | formin binding protein 1 | -0.0104438 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0104201 |
| JMJD1C | jumonji domain containing 1C | -0.0104107 |
| MXRA5 | matrix-remodelling associated 5 | -0.0103571 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -0.0103463 |
| SHTN1 | shootin 1 | -0.0103442 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0103378 |
| TCTA | T-cell leukemia translocation altered | -0.0102819 |
| CD99 | CD99 molecule | -0.0102154 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0101134 |
| PEG10 | paternally expressed 10 | -0.0100849 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0100299 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0100221 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00995715 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00994532 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00993682 |
| G0S2 | G0/G1 switch 2 | -0.00991114 |
| TRIM22 | tripartite motif containing 22 | -0.00986176 |
| MYO10 | myosin X | -0.0098318 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00982326 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00982326 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00976724 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | -0.00970305 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00968243 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00966068 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00962436 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00962262 |
| IL32 | interleukin 32 | -0.00955269 |
| ZNF281 | zinc finger protein 281 | -0.00955166 |
| COG7 | component of oligomeric golgi complex 7 | -0.00951519 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0095105 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00949924 |
| CTSL | cathepsin L | -0.00949057 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00945542 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00943455 |
| KLF6 | Kruppel-like factor 6 | -0.00942706 |
| TYMP | thymidine phosphorylase | -0.00942156 |
| DUSP4 | dual specificity phosphatase 4 | -0.00940094 |
| PTER | phosphotriesterase related | -0.00939701 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00939318 |
| HOMER2 | homer scaffolding protein 2 | -0.00936904 |
| HLA-F | major histocompatibility complex, class I, F | -0.00936311 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00935239 |
| TRIB3 | tribbles pseudokinase 3 | -0.00932277 |
| EZR | ezrin | -0.00931258 |
| GSN | gelsolin | -0.00930754 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00929916 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0092943 |
| CD14 | CD14 molecule | -0.00928106 |
| IRF7 | interferon regulatory factor 7 | -0.00925013 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.009231 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00921974 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00921099 |
| VLDLR | very low density lipoprotein receptor | -0.00920869 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00920376 |
| GLRX | glutaredoxin (thioltransferase) | -0.00919788 |
| USP18 | ubiquitin specific peptidase 18 | -0.00918432 |
| SERTAD2 | SERTA domain containing 2 | -0.00916569 |
| FHL2 | four and a half LIM domains 2 | -0.00916461 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.00916352 |
| PNN | pinin, desmosome associated protein | -0.00914944 |
| DUSP5 | dual specificity phosphatase 5 | -0.00914041 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.00911725 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00909592 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00909255 |
| TAOK3 | TAO kinase 3 | -0.00907725 |
| DMXL2 | Dmx-like 2 | -0.00907628 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0090219 |
| FMOD | fibromodulin | -0.00901937 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0089959 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00897635 |
| TTN | titin | -0.00895018 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00892546 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00891553 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00891467 |
| BRD4 | bromodomain containing 4 | -0.00890468 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00888635 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00883819 |
| CES1 | carboxylesterase 1 | -0.00882379 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00881621 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00881331 |
| ATF3 | activating transcription factor 3 | -0.00880877 |
| CPD | carboxypeptidase D | -0.00879404 |
| CCN3 | cellular communication network factor 3 | -0.00878786 |
| LAMB3 | laminin, beta 3 | -0.00876614 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00876513 |
| TRIB1 | tribbles pseudokinase 1 | -0.00874119 |
| CFD | complement factor D (adipsin) | -0.00865491 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00865203 |
| PELO | pelota homolog (Drosophila) | -0.00863601 |
| KHNYN | KH and NYN domain containing | -0.00862625 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00861187 |
| SDCBP | syndecan binding protein (syntenin) | -0.0085836 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.00857916 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00857211 |
| MYRF | myelin regulatory factor | -0.0085704 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.00856013 |
| ANXA5 | annexin A5 | -0.00855987 |
| PFKP | phosphofructokinase, platelet | -0.00854475 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00851599 |
| BAG3 | BCL2-associated athanogene 3 | -0.00851534 |
| RBM47 | RNA binding motif protein 47 | -0.00850916 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.00850235 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00845733 |
| STK26 | serine/threonine protein kinase 26 | -0.00845663 |
| APOD | apolipoprotein D | -0.00839899 |
| HIST1H2BK | histone cluster 1, H2bk | -0.0083602 |
| GOLGB1 | golgin B1 | -0.0083537 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.00834708 |
| HLA-C | major histocompatibility complex, class I, C | -0.00832383 |
| COL1A1 | collagen, type I, alpha 1 | -0.0083238 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00832289 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.00830738 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.00830058 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00829737 |
| PRSS23 | protease, serine, 23 | -0.0082724 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00826002 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00824706 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00824278 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00822229 |
| RSRP1 | arginine/serine-rich protein 1 | -0.00820524 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00820329 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.00819724 |
| BAG2 | BCL2-associated athanogene 2 | -0.008184 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.00817159 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00816646 |
| KRT17 | keratin 17, type I | -0.00816436 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00815225 |
| CCDC88A | coiled-coil domain containing 88A | -0.00814496 |
| MYOF | myoferlin | -0.00813784 |
| MMP2 | matrix metallopeptidase 2 | -0.00813691 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0081238 |
| PRNP | prion protein | -0.00810382 |
| AHNAK | AHNAK nucleoprotein | -0.00810135 |
| STXBP2 | syntaxin binding protein 2 | -0.00807981 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00807585 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00805922 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00804844 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00801604 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00801601 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.00801038 |
| STX16 | syntaxin 16 | -0.00799823 |
| KLK11 | kallikrein-related peptidase 11 | -0.00799361 |
| AIM2 | absent in melanoma 2 | -0.00796403 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00796361 |
| WASHC5 | WASH complex subunit 5 | -0.00793132 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00792692 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00792563 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00792444 |
| RAB7A | RAB7A, member RAS oncogene family | -0.00792192 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00790395 |
| MSX1 | msh homeobox 1 | -0.00790381 |
| FNBP4 | formin binding protein 4 | -0.007903 |
| KIF5B | kinesin family member 5B | -0.007903 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00790172 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00790037 |
| MIR22HG | MIR22 host gene | -0.00787099 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00785998 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00785475 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00781869 |
| SYCP2 | synaptonemal complex protein 2 | -0.00781257 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00778614 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.00778083 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0077792 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.00777156 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00775784 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00775457 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.00773758 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00773727 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00773468 |