CEP170 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description centrosomal protein 170kDa|The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9859)
External Link https://ncbi.nlm.nih.gov/gene/9859
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Genes

500 genes differentially expressed following the CEP170 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL12 chemokine (C-X-C motif) ligand 12 0.0223822
DCXR dicarbonyl/L-xylulose reductase 0.020668
OLFM4 olfactomedin 4 0.0186986
FGFR3 fibroblast growth factor receptor 3 0.0173742
HTRA1 HtrA serine peptidase 1 0.0167957
FABP1 fatty acid binding protein 1, liver 0.0154623
METTL7A methyltransferase like 7A 0.0153781
SDC1 syndecan 1 0.0153617
BIRC5 baculoviral IAP repeat containing 5 0.0150599
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.0145115
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0142686
CLCA1 chloride channel accessory 1 0.0140255
CXCL14 chemokine (C-X-C motif) ligand 14 0.0139161
GJA1 gap junction protein, alpha 1, 43kDa 0.0135111
AOC1 amine oxidase, copper containing 1 0.0134242
RPA3 replication protein A3, 14kDa 0.0133295
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.0131984
PLK1 polo-like kinase 1 0.0128627
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0128312
ADIRF adipogenesis regulatory factor 0.0127858
CCNF cyclin F 0.012641
JCHAIN joining chain of multimeric IgA and IgM 0.0124855
BRCA1 breast cancer 1, early onset 0.0124821
PITX3 paired-like homeodomain 3 0.0124248
TECR trans-2,3-enoyl-CoA reductase 0.0122654
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.0122017
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.012156
ICAM2 intercellular adhesion molecule 2 0.0121078
ACAT2 acetyl-CoA acetyltransferase 2 0.0121046
THBS1 thrombospondin 1 0.0119626
ECI2 enoyl-CoA delta isomerase 2 0.0119535
TMEM38B transmembrane protein 38B 0.011908
LEFTY1 left-right determination factor 1 0.0118953
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0117424
IFRD2 interferon-related developmental regulator 2 0.0116717
FST follistatin 0.0116585
BAMBI BMP and activin membrane-bound inhibitor 0.0115458
CDC20 cell division cycle 20 0.0115412
DNASE1L3 deoxyribonuclease I-like 3 0.0114486
TXNDC9 thioredoxin domain containing 9 0.011354
EIF5A eukaryotic translation initiation factor 5A 0.0112576
PLPBP pyridoxal phosphate binding protein 0.0112574
IGFBP5 insulin-like growth factor binding protein 5 0.0112322
CRELD2 cysteine-rich with EGF-like domains 2 0.0111072
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.0109752
VCAM1 vascular cell adhesion molecule 1 0.0109153
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0108616
FGFR4 fibroblast growth factor receptor 4 0.010818
AGTR1 angiotensin II receptor, type 1 0.0107647
FCGBP Fc fragment of IgG binding protein 0.0107007
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.0106917
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.0106187
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 0.0105935
KRT20 keratin 20, type I 0.0104745
LRRC17 leucine rich repeat containing 17 0.0104086
SELENOW selenoprotein W 0.010398
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.0103939
GSTM3 glutathione S-transferase mu 3 (brain) 0.0103746
DPEP1 dipeptidase 1 (renal) 0.010274
ADD3 adducin 3 (gamma) 0.0102563
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.0102354
PLN phospholamban 0.010195
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.0101831
ANPEP alanyl (membrane) aminopeptidase 0.0101383
ERLIN2 ER lipid raft associated 2 0.0101002
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0100979
SPINK4 serine peptidase inhibitor, Kazal type 4 0.0100894
LAGE3 L antigen family, member 3 0.0100763
WDR7 WD repeat domain 7 0.0100088
DIPK1A divergent protein kinase domain 1A 0.0099704
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.009926
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00992186
SRGN serglycin 0.00980572
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00979229
HBD hemoglobin, delta 0.00978067
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.00970935
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00961913
FXYD2 FXYD domain containing ion transport regulator 2 0.00959986
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.00959175
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00959098
SORBS3 sorbin and SH3 domain containing 3 0.00956714
CA12 carbonic anhydrase XII 0.0095498
H1-10 H1.10 linker histone 0.0095457
SIVA1 SIVA1, apoptosis-inducing factor 0.0095318
CDCA4 cell division cycle associated 4 0.00950331
EAF2 ELL associated factor 2 0.00949667
SURF1 surfeit 1 0.00942612
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00937829
AREG amphiregulin 0.00937367
C1QBP complement component 1, q subcomponent binding protein 0.00931392
CRYM crystallin, mu 0.00929072
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00927764
TMEM160 transmembrane protein 160 0.00926519
TSPAN7 tetraspanin 7 0.00926375
NNMT nicotinamide N-methyltransferase 0.0092603
GMDS GDP-mannose 4,6-dehydratase 0.00925581
REG1B regenerating islet-derived 1 beta 0.00924873
DAXX death-domain associated protein 0.00923449
C21ORF33 chromosome 21 open reading frame 33 0.00923348
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00921202
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00919375
CD320 CD320 molecule 0.0091134
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00910526
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00905951
ACAA2 acetyl-CoA acyltransferase 2 0.00905747
CENPX centromere protein X 0.00905076
CLC Charcot-Leyden crystal galectin 0.00900515
ALCAM activated leukocyte cell adhesion molecule 0.00894536
RUVBL1 RuvB-like AAA ATPase 1 0.00894523
WDR61 WD repeat domain 61 0.00887888
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00885569
MMP9 matrix metallopeptidase 9 0.00883288
ALDOB aldolase B, fructose-bisphosphate 0.00877305
DHCR24 24-dehydrocholesterol reductase 0.00876106
COA3 cytochrome c oxidase assembly factor 3 0.00874653
DEFA4 defensin, alpha 4, corticostatin 0.00874426
LGALS4 lectin, galactoside-binding, soluble, 4 0.00866829
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0086541
GPX2 glutathione peroxidase 2 0.00865381
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00864815
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.00864808
UROS uroporphyrinogen III synthase 0.0086432
HMGB3 high mobility group box 3 0.00863052
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00862884
PADI2 peptidyl arginine deiminase, type II 0.00862421
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00858593
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) 0.00858366
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00857615
NOTCH1 notch 1 0.00856675
ZNF329 zinc finger protein 329 0.00856225
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00854846
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.00853484
NOX1 NADPH oxidase 1 0.00852602
MT1E metallothionein 1E 0.00849819
CHEK2 checkpoint kinase 2 0.00846939
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00846762
SCAND1 SCAN domain containing 1 0.00845262
RUVBL2 RuvB-like AAA ATPase 2 0.00845102
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00842888
VAV3 vav 3 guanine nucleotide exchange factor 0.00842083
AMD1 adenosylmethionine decarboxylase 1 0.00839358
GSTO1 glutathione S-transferase omega 1 0.00836909
B3GNT1 0.00834078
DOK5 docking protein 5 0.00832551
ISYNA1 inositol-3-phosphate synthase 1 0.00830905
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00830398
ALDOA aldolase A, fructose-bisphosphate 0.00825614
LXN latexin 0.00825083
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00823457
CRIP2 cysteine-rich protein 2 0.00821963
CD38 CD38 molecule 0.00820862
ERI2 ERI1 exoribonuclease family member 2 0.00818707
MLF1 myeloid leukemia factor 1 0.00817372
RGS1 regulator of G-protein signaling 1 0.00816773
POLD2 polymerase (DNA directed), delta 2, accessory subunit 0.00815675
LST1 leukocyte specific transcript 1 0.00815658
TSNAX translin-associated factor X 0.00815201
DCTPP1 dCTP pyrophosphatase 1 0.00814786
LYRM4 LYR motif containing 4 0.00814105
UFSP2 UFM1-specific peptidase 2 0.00812688
SRM spermidine synthase 0.00811218
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00810465
CFI complement factor I 0.00810453
PIMREG PICALM interacting mitotic regulator 0.00809859
LBR lamin B receptor 0.00809552
NXT1 nuclear transport factor 2-like export factor 1 0.00809321
GLDC glycine dehydrogenase (decarboxylating) 0.00809227
CCNA2 cyclin A2 0.0080849
KIF4A kinesin family member 4A 0.00808357
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00805483
RNASEH2A ribonuclease H2, subunit A 0.00805002
GPA33 glycoprotein A33 (transmembrane) 0.00804495
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00800681
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0080067
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00797338
RWDD2B RWD domain containing 2B 0.007964
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00793854
ASB13 ankyrin repeat and SOCS box containing 13 0.007926
TSPO translocator protein (18kDa) 0.00792544
PLAT plasminogen activator, tissue 0.00791105
TPGS2 tubulin polyglutamylase complex subunit 2 0.00789335
ZDHHC4 zinc finger, DHHC-type containing 4 0.00788823
FASN fatty acid synthase 0.00788323
PRPF4 pre-mRNA processing factor 4 0.00786937
ATRAID all-trans retinoic acid-induced differentiation factor 0.00784992
ISOC2 isochorismatase domain containing 2 0.00783664
GAS1 growth arrest-specific 1 0.00783387
C1ORF54 chromosome 1 open reading frame 54 0.00782964
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 0.00781178
RGS4 regulator of G-protein signaling 4 0.00780734
CREBL2 cAMP responsive element binding protein-like 2 0.00779427
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.00778234
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.00774667
SRPX sushi-repeat containing protein, X-linked 0.00773011
S100A8 S100 calcium binding protein A8 0.00772825
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00772741
LRRC19 leucine rich repeat containing 19 0.00771649
TMEM50B transmembrane protein 50B 0.00771413
ZC3H4 zinc finger CCCH-type containing 4 0.00770109
UBE2C ubiquitin-conjugating enzyme E2C 0.0076946
FAM162A family with sequence similarity 162, member A 0.00767619
TMEM14B transmembrane protein 14B 0.00766347
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00765466
LTF lactotransferrin 0.00765428
GPER1 G protein-coupled estrogen receptor 1 0.00765308
PBLD phenazine biosynthesis-like protein domain containing 0.0076462
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.0076414
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00763875
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00763839
ATP5F1D ATP synthase F1 subunit delta 0.00762685
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00762499
NANOG Nanog homeobox 0.00761506
STOM stomatin 0.00759658
NPY1R neuropeptide Y receptor Y1 0.00758586
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.00756904
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00755899
ALPL alkaline phosphatase, liver/bone/kidney 0.00755783
ADI1 acireductone dioxygenase 1 0.00755227
CLIC5 chloride intracellular channel 5 0.00754481
ZG16 zymogen granule protein 16 0.00753967
TYRP1 tyrosinase-related protein 1 0.00753748
NT5DC2 5'-nucleotidase domain containing 2 0.00751997
SIRT5 sirtuin 5 0.00751376
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 0.00751304
CBR3 carbonyl reductase 3 0.00751078
ELOVL6 ELOVL fatty acid elongase 6 0.00750731
SLC2A4RG SLC2A4 regulator 0.00750696
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.00750588
IFT46 intraflagellar transport 46 0.00749957
RPS5 ribosomal protein S5 0.00748945
JAG2 jagged 2 0.00748405
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00747351
OIP5 Opa interacting protein 5 0.00746347
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00746198
COPS4 COP9 signalosome subunit 4 0.00745194
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.00743567
GLB1 galactosidase, beta 1 0.00740757
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00740108
HPF1 histone PARylation factor 1 0.00739676
JADE2 jade family PHD finger 2 0.00739162
AK4 adenylate kinase 4 0.00738299
HMBS hydroxymethylbilane synthase 0.00736213
ARL3 ADP-ribosylation factor-like 3 0.00736073
SEH1L SEH1-like (S. cerevisiae) 0.00735752
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00735253
CAMP cathelicidin antimicrobial peptide 0.00734778
SV2A synaptic vesicle glycoprotein 2A 0.00733346
RAD51 RAD51 recombinase 0.00732287
AHCY adenosylhomocysteinase 0.00730815
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00729629

decreased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 -0.0265959
IFI44L interferon-induced protein 44-like -0.0247936
MX1 MX dynamin-like GTPase 1 -0.0233422
ISG15 ISG15 ubiquitin-like modifier -0.0203179
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0186789
TENT5A terminal nucleotidyltransferase 5A -0.0170869
FN1 fibronectin 1 -0.0170058
HSPA1A heat shock 70kDa protein 1A -0.0169865
IFI44 interferon-induced protein 44 -0.0166395
COL15A1 collagen, type XV, alpha 1 -0.0160433
YBX3 Y box binding protein 3 -0.0158845
HMOX1 heme oxygenase 1 -0.0156974
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0150604
XIC X chromosome inactivation center -0.0146153
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0145309
DUSP10 dual specificity phosphatase 10 -0.0141818
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0141766
HSPB8 heat shock 22kDa protein 8 -0.01406
EGFL6 EGF-like-domain, multiple 6 -0.0139985
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0138669
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.0135371
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.01344
IGF2R insulin-like growth factor 2 receptor -0.0133439
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.0131366
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0130117
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0129947
GOLGA8A golgin A8 family, member A -0.0129579
GNAS GNAS complex locus -0.0129263
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.0129136
EGR2 early growth response 2 -0.0128278
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0127408
S100A11 S100 calcium binding protein A11 -0.0126621
TGM2 transglutaminase 2 -0.0124914
NPC1 Niemann-Pick disease, type C1 -0.0124486
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0121297
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0120988
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0118939
BST2 bone marrow stromal cell antigen 2 -0.0118568
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0117735
GAB2 GRB2-associated binding protein 2 -0.0117722
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0117686
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.0117252
NIT1 nitrilase 1 -0.0117196
IRS2 insulin receptor substrate 2 -0.0117133
TGFBI transforming growth factor, beta-induced, 68kDa -0.0116742
TACSTD2 tumor-associated calcium signal transducer 2 -0.0116579
SAMD9 sterile alpha motif domain containing 9 -0.0115646
ANXA3 annexin A3 -0.0114995
XAF1 XIAP associated factor 1 -0.0114319
NBPF10 neuroblastoma breakpoint family, member 10 -0.0114277
RSRC2 arginine/serine-rich coiled-coil 2 -0.0114011
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0113887
LYST lysosomal trafficking regulator -0.0113857
IFI6 interferon, alpha-inducible protein 6 -0.0113502
COL4A5 collagen, type IV, alpha 5 -0.0112101
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.0111666
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0111567
SOX4 SRY (sex determining region Y)-box 4 -0.0111303
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0111117
S100A10 S100 calcium binding protein A10 -0.0110648
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.0110312
EGR1 early growth response 1 -0.0110116
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0109747
JAK1 Janus kinase 1 -0.0109004
IFI16 interferon, gamma-inducible protein 16 -0.0108685
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0108655
ANO1 anoctamin 1, calcium activated chloride channel -0.0108469
HLA-B major histocompatibility complex, class I, B -0.0108358
SSX1 synovial sarcoma, X breakpoint 1 -0.010815
NELL2 NEL-like 2 (chicken) -0.0107747
ADGRG2 adhesion G protein-coupled receptor G2 -0.0107595
TARS1 threonyl-tRNA synthetase 1 -0.0107121
PLK2 polo-like kinase 2 -0.0106814
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.0106761
CST1 cystatin SN -0.0106304
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0106042
KRT7 keratin 7, type II -0.0105813
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.0105505
IRF9 interferon regulatory factor 9 -0.010539
COPA coatomer protein complex, subunit alpha -0.0104496
FNBP1 formin binding protein 1 -0.0104438
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.0104201
JMJD1C jumonji domain containing 1C -0.0104107
MXRA5 matrix-remodelling associated 5 -0.0103571
LGALS8 lectin, galactoside-binding, soluble, 8 -0.0103463
SHTN1 shootin 1 -0.0103442
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.0103378
TCTA T-cell leukemia translocation altered -0.0102819
CD99 CD99 molecule -0.0102154
RHOBTB3 Rho-related BTB domain containing 3 -0.0101134
PEG10 paternally expressed 10 -0.0100849
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0100299
ZBTB35 zinc finger and BTB domain containing 35 -0.0100221
CSAD cysteine sulfinic acid decarboxylase -0.00995715
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.00994532
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00993682
G0S2 G0/G1 switch 2 -0.00991114
TRIM22 tripartite motif containing 22 -0.00986176
MYO10 myosin X -0.0098318
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00982326
AKAP8 A kinase (PRKA) anchor protein 8 -0.00982326
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.00976724
AKAP17A A kinase (PRKA) anchor protein 17A -0.00970305
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00968243
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00966068
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.00962436
NCF2 neutrophil cytosolic factor 2 -0.00962262
IL32 interleukin 32 -0.00955269
ZNF281 zinc finger protein 281 -0.00955166
COG7 component of oligomeric golgi complex 7 -0.00951519
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0095105
MCM2 minichromosome maintenance complex component 2 -0.00949924
CTSL cathepsin L -0.00949057
SSBP2 single-stranded DNA binding protein 2 -0.00945542
DOCK9 dedicator of cytokinesis 9 -0.00943455
KLF6 Kruppel-like factor 6 -0.00942706
TYMP thymidine phosphorylase -0.00942156
DUSP4 dual specificity phosphatase 4 -0.00940094
PTER phosphotriesterase related -0.00939701
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00939318
HOMER2 homer scaffolding protein 2 -0.00936904
HLA-F major histocompatibility complex, class I, F -0.00936311
NIBAN1 niban apoptosis regulator 1 -0.00935239
TRIB3 tribbles pseudokinase 3 -0.00932277
EZR ezrin -0.00931258
GSN gelsolin -0.00930754
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00929916
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0092943
CD14 CD14 molecule -0.00928106
IRF7 interferon regulatory factor 7 -0.00925013
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.009231
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00921974
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00921099
VLDLR very low density lipoprotein receptor -0.00920869
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00920376
GLRX glutaredoxin (thioltransferase) -0.00919788
USP18 ubiquitin specific peptidase 18 -0.00918432
SERTAD2 SERTA domain containing 2 -0.00916569
FHL2 four and a half LIM domains 2 -0.00916461
UBE2H ubiquitin-conjugating enzyme E2H -0.00916352
PNN pinin, desmosome associated protein -0.00914944
DUSP5 dual specificity phosphatase 5 -0.00914041
PARP8 poly (ADP-ribose) polymerase family, member 8 -0.00911725
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00909592
MKNK1 MAP kinase interacting serine/threonine kinase 1 -0.00909255
TAOK3 TAO kinase 3 -0.00907725
DMXL2 Dmx-like 2 -0.00907628
LEF1 lymphoid enhancer-binding factor 1 -0.0090219
FMOD fibromodulin -0.00901937
NIPBL Nipped-B homolog (Drosophila) -0.0089959
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00897635
TTN titin -0.00895018
DDIT3 DNA-damage-inducible transcript 3 -0.00892546
IFIH1 interferon induced with helicase C domain 1 -0.00891553
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00891467
BRD4 bromodomain containing 4 -0.00890468
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00888635
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00883819
CES1 carboxylesterase 1 -0.00882379
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00881621
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00881331
ATF3 activating transcription factor 3 -0.00880877
CPD carboxypeptidase D -0.00879404
CCN3 cellular communication network factor 3 -0.00878786
LAMB3 laminin, beta 3 -0.00876614
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00876513
TRIB1 tribbles pseudokinase 1 -0.00874119
CFD complement factor D (adipsin) -0.00865491
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00865203
PELO pelota homolog (Drosophila) -0.00863601
KHNYN KH and NYN domain containing -0.00862625
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00861187
SDCBP syndecan binding protein (syntenin) -0.0085836
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00857916
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.00857211
MYRF myelin regulatory factor -0.0085704
DKK2 dickkopf WNT signaling pathway inhibitor 2 -0.00856013
ANXA5 annexin A5 -0.00855987
PFKP phosphofructokinase, platelet -0.00854475
ADAM10 ADAM metallopeptidase domain 10 -0.00851599
BAG3 BCL2-associated athanogene 3 -0.00851534
RBM47 RNA binding motif protein 47 -0.00850916
PTPRM protein tyrosine phosphatase, receptor type, M -0.00850235
RAB9A RAB9A, member RAS oncogene family -0.00845733
STK26 serine/threonine protein kinase 26 -0.00845663
APOD apolipoprotein D -0.00839899
HIST1H2BK histone cluster 1, H2bk -0.0083602
GOLGB1 golgin B1 -0.0083537
ZC3H11A zinc finger CCCH-type containing 11A -0.00834708
HLA-C major histocompatibility complex, class I, C -0.00832383
COL1A1 collagen, type I, alpha 1 -0.0083238
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00832289
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.00830738
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -0.00830058
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00829737
PRSS23 protease, serine, 23 -0.0082724
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00826002
LRP4 low density lipoprotein receptor-related protein 4 -0.00824706
PILRB paired immunoglobin-like type 2 receptor beta -0.00824278
KDM6A lysine (K)-specific demethylase 6A -0.00822229
RSRP1 arginine/serine-rich protein 1 -0.00820524
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.00820329
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.00819724
BAG2 BCL2-associated athanogene 2 -0.008184
NNT nicotinamide nucleotide transhydrogenase -0.00817159
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00816646
KRT17 keratin 17, type I -0.00816436
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00815225
CCDC88A coiled-coil domain containing 88A -0.00814496
MYOF myoferlin -0.00813784
MMP2 matrix metallopeptidase 2 -0.00813691
PLAAT3 phospholipase A and acyltransferase 3 -0.0081238
PRNP prion protein -0.00810382
AHNAK AHNAK nucleoprotein -0.00810135
STXBP2 syntaxin binding protein 2 -0.00807981
F13A1 coagulation factor XIII, A1 polypeptide -0.00807585
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00805922
FNDC3B fibronectin type III domain containing 3B -0.00804844
TRIO trio Rho guanine nucleotide exchange factor -0.00801604
AMDHD2 amidohydrolase domain containing 2 -0.00801601
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -0.00801038
STX16 syntaxin 16 -0.00799823
KLK11 kallikrein-related peptidase 11 -0.00799361
AIM2 absent in melanoma 2 -0.00796403
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00796361
WASHC5 WASH complex subunit 5 -0.00793132
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00792692
PNISR PNN-interacting serine/arginine-rich protein -0.00792563
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00792444
RAB7A RAB7A, member RAS oncogene family -0.00792192
TIGAR TP53 induced glycolysis regulatory phosphatase -0.00790395
MSX1 msh homeobox 1 -0.00790381
FNBP4 formin binding protein 4 -0.007903
KIF5B kinesin family member 5B -0.007903
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00790172
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00790037
MIR22HG MIR22 host gene -0.00787099
FRS2 fibroblast growth factor receptor substrate 2 -0.00785998
OFD1 oral-facial-digital syndrome 1 -0.00785475
BHLHE40 basic helix-loop-helix family, member e40 -0.00781869
SYCP2 synaptonemal complex protein 2 -0.00781257
HSPA4L heat shock 70kDa protein 4-like -0.00778614
SENP6 SUMO1/sentrin specific peptidase 6 -0.00778083
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.0077792
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.00777156
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00775784
CCR7 chemokine (C-C motif) receptor 7 -0.00775457
KTN1 kinectin 1 (kinesin receptor) -0.00773758
ACTA1 actin, alpha 1, skeletal muscle -0.00773727
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00773468