CERIVASTATIN Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. (Chemical Entities of Biological Interest Ontology, CHEBI_3558)
External Link https://dgidb.org/results?searchType=drug&searchTerms=CERIVASTATIN
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Genes

4 interacting proteins for the CERIVASTATIN drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
RYR2 ryanodine receptor 2 (cardiac) 2.406
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.03788
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.980222
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.653481