| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | complement factor H-related 5|This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 81494) |
| External Link | https://ncbi.nlm.nih.gov/gene/81494 |
| Similar Terms | |
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499 genes differentially expressed following the CFHR5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0199925 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0109043 |
| SORD | sorbitol dehydrogenase | 0.0108726 |
| CTSH | cathepsin H | 0.0106139 |
| IFI44 | interferon-induced protein 44 | 0.0105418 |
| HOPX | HOP homeobox | 0.0103972 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00977539 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00941709 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00916238 |
| CD99 | CD99 molecule | 0.00915251 |
| MARCKSL1 | MARCKS-like 1 | 0.00901509 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00895335 |
| CD93 | CD93 molecule | 0.00895057 |
| NID1 | nidogen 1 | 0.00869582 |
| S100A2 | S100 calcium binding protein A2 | 0.00862251 |
| MX2 | MX dynamin-like GTPase 2 | 0.00861629 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00854068 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.0085194 |
| NELL2 | NEL-like 2 (chicken) | 0.00851732 |
| GPC3 | glypican 3 | 0.00851618 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00845159 |
| SELENOF | selenoprotein F | 0.00842883 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00838986 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00838664 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00823472 |
| FGG | fibrinogen gamma chain | 0.00823246 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00819088 |
| AK4 | adenylate kinase 4 | 0.00818633 |
| CFI | complement factor I | 0.00812546 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00811395 |
| GLO1 | glyoxalase I | 0.00797953 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00791484 |
| IFI44L | interferon-induced protein 44-like | 0.00791354 |
| A2M | alpha-2-macroglobulin | 0.00786967 |
| SNX10 | sorting nexin 10 | 0.00783952 |
| KRT1 | keratin 1, type II | 0.00780871 |
| FRZB | frizzled-related protein | 0.00773436 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0076768 |
| DSP | desmoplakin | 0.00767585 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00759092 |
| CHKB | choline kinase beta | 0.00755979 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00754378 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.0075163 |
| MAGEA3 | melanoma antigen family A3 | 0.00746586 |
| CD69 | CD69 molecule | 0.00742762 |
| RHOA | ras homolog family member A | 0.00742131 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00738164 |
| COL5A2 | collagen, type V, alpha 2 | 0.0073778 |
| PRKCB | protein kinase C, beta | 0.00736257 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00733327 |
| ESD | esterase D | 0.00732895 |
| F2R | coagulation factor II (thrombin) receptor | 0.00732447 |
| MMP11 | matrix metallopeptidase 11 | 0.00730589 |
| LOXL1 | lysyl oxidase-like 1 | 0.00729581 |
| MMD | monocyte to macrophage differentiation-associated | 0.00729032 |
| PRAME | preferentially expressed antigen in melanoma | 0.00729021 |
| USP18 | ubiquitin specific peptidase 18 | 0.00723794 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00716513 |
| CD2 | CD2 molecule | 0.00714844 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00713839 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00708342 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.00707495 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00702388 |
| CD200 | CD200 molecule | 0.00698516 |
| MGP | matrix Gla protein | 0.0069439 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00689873 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00680425 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00676523 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00671343 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00668524 |
| CHPT1 | choline phosphotransferase 1 | 0.00668453 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00667797 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.0066409 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00658174 |
| BCHE | butyrylcholinesterase | 0.0065735 |
| LYZ | lysozyme | 0.00656106 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00653518 |
| FZD6 | frizzled class receptor 6 | 0.00650513 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.0064779 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00647176 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00645806 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00643711 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00642276 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00641662 |
| TMEM14A | transmembrane protein 14A | 0.0063842 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0063794 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00633783 |
| WDR61 | WD repeat domain 61 | 0.00633755 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0063314 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00633032 |
| AFP | alpha-fetoprotein | 0.00632406 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00628235 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00627374 |
| NCK1 | NCK adaptor protein 1 | 0.00626981 |
| DCK | deoxycytidine kinase | 0.00624592 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00623468 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00623425 |
| EMP2 | epithelial membrane protein 2 | 0.00617768 |
| RPS5 | ribosomal protein S5 | 0.00614869 |
| EDNRB | endothelin receptor type B | 0.00609446 |
| MX1 | MX dynamin-like GTPase 1 | 0.00607455 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00604871 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00604802 |
| PRF1 | perforin 1 (pore forming protein) | 0.00603436 |
| SELL | selectin L | 0.00602437 |
| C7 | complement component 7 | 0.00602102 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00599548 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00599429 |
| SFTPC | surfactant protein C | 0.00598351 |
| TCTA | T-cell leukemia translocation altered | 0.00598334 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00595603 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00594434 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00594252 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00593517 |
| HP | haptoglobin | 0.00592202 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0059196 |
| COLEC12 | collectin sub-family member 12 | 0.00591726 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00588475 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00587487 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00584668 |
| ITM2A | integral membrane protein 2A | 0.00583435 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00582452 |
| AGR2 | anterior gradient 2 | 0.00581341 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00579712 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.00578979 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00578702 |
| GANAB | glucosidase, alpha; neutral AB | 0.00577668 |
| RBBP4 | retinoblastoma binding protein 4 | 0.0057552 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00571085 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00569641 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00568075 |
| RRAGA | Ras-related GTP binding A | 0.00567018 |
| EMP1 | epithelial membrane protein 1 | 0.00566953 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00565743 |
| KIFAP3 | kinesin-associated protein 3 | 0.00563699 |
| MDFIC | MyoD family inhibitor domain containing | 0.0056312 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00562411 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00561526 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00561192 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00560757 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00556989 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0055578 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00555506 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00555087 |
| FLOT1 | flotillin 1 | 0.0055167 |
| MAGEA12 | melanoma antigen family A12 | 0.00551182 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00551042 |
| DDHD2 | DDHD domain containing 2 | 0.00550384 |
| METRN | meteorin, glial cell differentiation regulator | 0.00550021 |
| VSNL1 | visinin-like 1 | 0.00548357 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00547702 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.005469 |
| PIR | pirin (iron-binding nuclear protein) | 0.00545107 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00544492 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00544422 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00544199 |
| HYAL1 | hyaluronoglucosaminidase 1 | 0.00544171 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.0054387 |
| SPP1 | secreted phosphoprotein 1 | 0.00543682 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00543388 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00541752 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00541258 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.0053997 |
| CCNA2 | cyclin A2 | 0.00539848 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00534702 |
| IL10RB | interleukin 10 receptor, beta | 0.00530714 |
| HOMER1 | homer scaffolding protein 1 | 0.00530266 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00530079 |
| TFDP1 | transcription factor Dp-1 | 0.00529226 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00528253 |
| NRN1 | neuritin 1 | 0.00527341 |
| MEAF6 | MYST/Esa1-associated factor 6 | 0.00526792 |
| PGC | progastricsin (pepsinogen C) | 0.00526652 |
| REEP5 | receptor accessory protein 5 | 0.0052653 |
| S100A7 | S100 calcium binding protein A7 | 0.00526448 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00525808 |
| APOA2 | apolipoprotein A-II | 0.00524657 |
| S100B | S100 calcium binding protein B | 0.0052439 |
| COPS4 | COP9 signalosome subunit 4 | 0.00523655 |
| GLTP | glycolipid transfer protein | 0.00523376 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | 0.00523358 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00522184 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | 0.00522183 |
| KRT2 | keratin 2, type II | 0.00521134 |
| COL3A1 | collagen, type III, alpha 1 | 0.00520173 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00519357 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00519325 |
| CD53 | CD53 molecule | 0.00519218 |
| TYRP1 | tyrosinase-related protein 1 | 0.00518497 |
| SFTPA2 | surfactant protein A2 | 0.00517097 |
| MMP12 | matrix metallopeptidase 12 | 0.00515675 |
| ITK | IL2-inducible T-cell kinase | 0.00515095 |
| GPR65 | G protein-coupled receptor 65 | 0.00514758 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00514679 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00514154 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0051413 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00512811 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00512723 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00510746 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 0.00510745 |
| SELENBP1 | selenium binding protein 1 | 0.00509537 |
| APOB | apolipoprotein B | 0.00509329 |
| DMXL1 | Dmx-like 1 | 0.00507737 |
| MEN1 | multiple endocrine neoplasia I | 0.00507185 |
| HDAC1 | histone deacetylase 1 | 0.0050685 |
| INHBB | inhibin, beta B | 0.00506144 |
| TSPAN6 | tetraspanin 6 | 0.00504941 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 0.00504897 |
| FASTKD3 | FAST kinase domains 3 | 0.00504832 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00504603 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.0050419 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00502728 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.0050048 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00500477 |
| STK17A | serine/threonine kinase 17a | 0.00500417 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.0049903 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00498956 |
| TSPAN8 | tetraspanin 8 | 0.00498414 |
| RTN1 | reticulon 1 | 0.00498307 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00497643 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00497054 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00496734 |
| DMD | dystrophin | 0.00495625 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0049537 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00495201 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.00494864 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00494061 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.00493965 |
| APOA1 | apolipoprotein A-I | 0.00493466 |
| SSR1 | signal sequence receptor, alpha | 0.00493153 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00492769 |
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.00492078 |
| CD96 | CD96 molecule | 0.00491419 |
| ZNF217 | zinc finger protein 217 | 0.00491162 |
| TMEM14B | transmembrane protein 14B | 0.00491085 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.00489942 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00489745 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00489506 |
| SMYD2 | SET and MYND domain containing 2 | 0.00488279 |
| TXN | thioredoxin | 0.00487961 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00487314 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.0048668 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00486109 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00485363 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00483557 |
| CD320 | CD320 molecule | 0.00483398 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00483204 |
| YEATS4 | YEATS domain containing 4 | 0.00483123 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00482917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0207334 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0195784 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0141233 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0130208 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0111887 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.0101327 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0101239 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00981141 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00975023 |
| BMP2 | bone morphogenetic protein 2 | -0.00970613 |
| PLK2 | polo-like kinase 2 | -0.00966082 |
| RND3 | Rho family GTPase 3 | -0.00948621 |
| HOMER3 | homer scaffolding protein 3 | -0.00942112 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0093185 |
| PTHLH | parathyroid hormone-like hormone | -0.00921867 |
| SIRPA | signal-regulatory protein alpha | -0.00906994 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00901891 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00901474 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00895853 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0089286 |
| MPO | myeloperoxidase | -0.00884889 |
| ANXA3 | annexin A3 | -0.00881361 |
| MMP1 | matrix metallopeptidase 1 | -0.00868587 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00866946 |
| MGLL | monoglyceride lipase | -0.00864352 |
| ELANE | elastase, neutrophil expressed | -0.00863896 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00857634 |
| AZU1 | azurocidin 1 | -0.00856102 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00853858 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00847394 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00834635 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00832536 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00827091 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0082097 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00819486 |
| FBN2 | fibrillin 2 | -0.00818261 |
| PEG10 | paternally expressed 10 | -0.00809649 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00804914 |
| PROM1 | prominin 1 | -0.00797029 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.0079403 |
| CTBP2 | C-terminal binding protein 2 | -0.00791403 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00786831 |
| NOTCH2NL | notch 2 N-terminal like | -0.00775942 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00755037 |
| IPO13 | importin 13 | -0.00754797 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00754724 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00753702 |
| SGCE | sarcoglycan, epsilon | -0.00747849 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00746658 |
| GOLGA8A | golgin A8 family, member A | -0.00739679 |
| XIC | X chromosome inactivation center | -0.00735235 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00730191 |
| IRX5 | iroquois homeobox 5 | -0.00723174 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00722575 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00721215 |
| ZNF423 | zinc finger protein 423 | -0.00720108 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00718651 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00715958 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00714311 |
| CRYAB | crystallin, alpha B | -0.00710669 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00708834 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00708518 |
| RTN2 | reticulon 2 | -0.00704691 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00704083 |
| AMOTL2 | angiomotin like 2 | -0.00703364 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00702452 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00701957 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00698766 |
| TUFT1 | tuftelin 1 | -0.00695396 |
| CLC | Charcot-Leyden crystal galectin | -0.00691032 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00685991 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0068325 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00680598 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00679952 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00677682 |
| EIF6 | eukaryotic translation initiation factor 6 | -0.00675117 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.00672125 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00669713 |
| IRS2 | insulin receptor substrate 2 | -0.00668797 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00665091 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.006646 |
| CDV3 | CDV3 homolog (mouse) | -0.00661844 |
| CLU | clusterin | -0.0066172 |
| CTSG | cathepsin G | -0.00661206 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00660535 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.00654758 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00653201 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00652526 |
| KAZN | kazrin, periplakin interacting protein | -0.00650085 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00648723 |
| LONP1 | lon peptidase 1, mitochondrial | -0.00641714 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00641331 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00641245 |
| BBX | bobby sox homolog (Drosophila) | -0.00638473 |
| S100A8 | S100 calcium binding protein A8 | -0.00637616 |
| MMP3 | matrix metallopeptidase 3 | -0.00637604 |
| KRT7 | keratin 7, type II | -0.00637576 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00634103 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00632331 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0063157 |
| FRY | furry homolog (Drosophila) | -0.00630199 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00629679 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00628398 |
| PXDN | peroxidasin | -0.00621353 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00621298 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00620499 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.00619797 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00614997 |
| HTRA1 | HtrA serine peptidase 1 | -0.00614934 |
| PRTN3 | proteinase 3 | -0.00613907 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00613723 |
| AREG | amphiregulin | -0.00613543 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00608644 |
| NNMT | nicotinamide N-methyltransferase | -0.00608114 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.0060728 |
| MIR22HG | MIR22 host gene | -0.00605122 |
| PFKM | phosphofructokinase, muscle | -0.00600311 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00599633 |
| GAS6 | growth arrest-specific 6 | -0.00599285 |
| KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 | -0.00594246 |
| TRRAP | transformation/transcription domain-associated protein | -0.00592505 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00591874 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0059144 |
| OSBPL1A | oxysterol binding protein-like 1A | -0.00588131 |
| FBXO11 | F-box protein 11 | -0.00587387 |
| KIAA0930 | KIAA0930 | -0.00587376 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0058251 |
| RRAGD | Ras-related GTP binding D | -0.00580229 |
| BLNK | B-cell linker | -0.00579543 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00578521 |
| CDK14 | cyclin-dependent kinase 14 | -0.00578332 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.00577876 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -0.00577806 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -0.00577042 |
| PXDC1 | PX domain containing 1 | -0.00575679 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00574774 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.005743 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00572819 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | -0.00571375 |
| CAMP | cathelicidin antimicrobial peptide | -0.0057086 |
| AUTS2 | autism susceptibility candidate 2 | -0.00570303 |
| JMJD6 | jumonji domain containing 6 | -0.00569947 |
| APOD | apolipoprotein D | -0.00569674 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00568143 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00567347 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00566823 |
| USP47 | ubiquitin specific peptidase 47 | -0.00565887 |
| OLFM4 | olfactomedin 4 | -0.00565441 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.0056443 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00564247 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00561503 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00561182 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00558845 |
| CA2 | carbonic anhydrase II | -0.00554631 |
| LTF | lactotransferrin | -0.00554334 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00553177 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00553103 |
| FAIM | Fas apoptotic inhibitory molecule | -0.00551155 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00550395 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00550067 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00549153 |
| TARP | TCR gamma alternate reading frame protein | -0.00548377 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00547171 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00547083 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00546678 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00544174 |
| BPI | bactericidal/permeability-increasing protein | -0.0054374 |
| TLE4 | transducin-like enhancer of split 4 | -0.00543594 |
| BICC1 | BicC family RNA binding protein 1 | -0.00542566 |
| ZNF160 | zinc finger protein 160 | -0.00541453 |
| MITF | microphthalmia-associated transcription factor | -0.00541302 |
| RIN2 | Ras and Rab interactor 2 | -0.0053922 |
| BMP4 | bone morphogenetic protein 4 | -0.00538199 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00537988 |
| PERP | PERP, TP53 apoptosis effector | -0.00536379 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00535748 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00533946 |
| AK1 | adenylate kinase 1 | -0.00532065 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00531068 |
| ADIRF | adipogenesis regulatory factor | -0.00530954 |
| LDB3 | LIM domain binding 3 | -0.00530754 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00530514 |
| PYCARD | PYD and CARD domain containing | -0.0053044 |
| FAM13A | family with sequence similarity 13, member A | -0.00529816 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00526119 |
| LCN2 | lipocalin 2 | -0.00525585 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00525327 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | -0.00524189 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00523538 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00523461 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00523456 |
| ZNF721 | zinc finger protein 721 | -0.00522917 |
| SETD6 | SET domain containing 6 | -0.00521871 |
| WASF1 | WAS protein family, member 1 | -0.00521085 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.00519684 |
| PDZK1 | PDZ domain containing 1 | -0.00518472 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00517844 |
| PIP | prolactin-induced protein | -0.0051729 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.00516802 |
| NFASC | neurofascin | -0.00513843 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00511008 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00510177 |
| NBEA | neurobeachin | -0.0050889 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00508556 |
| TSPO | translocator protein (18kDa) | -0.00506821 |
| FLII | flightless I homolog (Drosophila) | -0.00506805 |
| SRRT | serrate, RNA effector molecule | -0.00505871 |
| EREG | epiregulin | -0.00502539 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | -0.00499173 |
| KLHL24 | kelch-like family member 24 | -0.00498652 |
| NAV2 | neuron navigator 2 | -0.00498486 |
| TPCN1 | two pore segment channel 1 | -0.00495563 |
| TSPAN1 | tetraspanin 1 | -0.00493607 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00491862 |
| S100A11 | S100 calcium binding protein A11 | -0.00491745 |
| MYLIP | myosin regulatory light chain interacting protein | -0.00490257 |
| CUX1 | cut-like homeobox 1 | -0.00490068 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.004896 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00487925 |
| STXBP2 | syntaxin binding protein 2 | -0.00487409 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00485808 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00485717 |
| MMP8 | matrix metallopeptidase 8 | -0.00485232 |
| HIP1R | huntingtin interacting protein 1 related | -0.0048522 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00484411 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | -0.00484409 |
| TWNK | twinkle mtDNA helicase | -0.00482277 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00482236 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00482156 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00480689 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.00480166 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00477437 |
| STK39 | serine threonine kinase 39 | -0.00474981 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.00473107 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00472832 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00471793 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00471584 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00471576 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00470982 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0046943 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00469175 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00468888 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00467868 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.0046679 |
| LEFTY1 | left-right determination factor 1 | -0.00466008 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00465391 |
| ACKR3 | atypical chemokine receptor 3 | -0.00463911 |
| L1CAM | L1 cell adhesion molecule | -0.0046364 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | -0.00463071 |
| KRT19 | keratin 19, type I | -0.00462691 |
